Class information for:
Level 1: P GLYCOPROTEIN//PHARMACORESISTANCE//TARIQUIDAR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9862 1114 48.6 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
230 3       P GLYCOPROTEIN//FMO3//TRIMETHYLAMINURIA 49374
747 2             P GLYCOPROTEIN//MULTIDRUG RESISTANCE//MDR1 12474
9862 1                   P GLYCOPROTEIN//PHARMACORESISTANCE//TARIQUIDAR 1114

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 P GLYCOPROTEIN authKW 784462 36% 7% 396
2 PHARMACORESISTANCE authKW 645133 6% 37% 64
3 TARIQUIDAR authKW 548159 3% 67% 30
4 PHARMACOL TOXICOL PHARM address 463607 9% 17% 100
5 C 11VERAPAMIL authKW 438544 1% 100% 16
6 R C 11VERAPAMIL authKW 416901 2% 89% 17
7 BLOOD BRAIN BARRIER authKW 391125 30% 4% 339
8 MULTIDRUG TRANSPORTER authKW 341143 3% 33% 38
9 C 11TARIQUIDAR authKW 164454 1% 100% 6
10 BREAST CANCER RESISTANCE PROTEIN authKW 154669 3% 16% 35

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 3927 36% 0% 396
2 Clinical Neurology 2517 22% 0% 241
3 Neurosciences 2273 28% 0% 308
4 Chemistry, Medicinal 308 6% 0% 63
5 Radiology, Nuclear Medicine & Medical Imaging 233 7% 0% 76
6 Medicine, Research & Experimental 118 5% 0% 56
7 Biochemistry & Molecular Biology 40 10% 0% 111
8 Endocrinology & Metabolism 12 3% 0% 29
9 Neuroimaging 11 1% 0% 6
10 Geriatrics & Gerontology 11 1% 0% 9

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACOL TOXICOL PHARM 463607 9% 17% 100
2 BIOFORDRUG SRL 122089 1% 64% 7
3 PROBE SECTINAGE KU 82227 0% 100% 3
4 UNITE NEURO PHARMACO NUTR 82227 0% 100% 3
5 MEMBRANE TRANSPORT DRUG TARGETING 56364 1% 17% 12
6 AAB BIOMED SCI NEUROVASC BIOL 54818 0% 100% 2
7 CELL BIOL NEUROBIOL DR E DE ROBERTIS 54818 0% 100% 2
8 EPILEPSY UNITSECT CLIN PHARMACOL STROKE MED 54818 0% 100% 2
9 MOL PROBE 48723 0% 44% 4
10 EA 2706 38061 0% 28% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EPILEPSIA 12154 6% 1% 63
2 PHARMACOGENOMICS 11242 2% 2% 27
3 EPILEPSY RESEARCH 7208 3% 1% 32
4 NUCLEAR MEDICINE AND BIOLOGY 2949 2% 1% 20
5 PHARMACOGENETICS AND GENOMICS 2905 1% 1% 11
6 EJNMMI RESEARCH 2241 1% 1% 6
7 JOURNAL OF NUCLEAR MEDICINE 2074 3% 0% 28
8 JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 2025 2% 0% 20
9 CURRENT PHARMACEUTICAL DESIGN 1740 2% 0% 20
10 SEIZURE-EUROPEAN JOURNAL OF EPILEPSY 1605 1% 0% 12

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 P GLYCOPROTEIN 784462 36% 7% 396 Search P+GLYCOPROTEIN Search P+GLYCOPROTEIN
2 PHARMACORESISTANCE 645133 6% 37% 64 Search PHARMACORESISTANCE Search PHARMACORESISTANCE
3 TARIQUIDAR 548159 3% 67% 30 Search TARIQUIDAR Search TARIQUIDAR
4 C 11VERAPAMIL 438544 1% 100% 16 Search C+11VERAPAMIL Search C+11VERAPAMIL
5 R C 11VERAPAMIL 416901 2% 89% 17 Search R+C+11VERAPAMIL Search R+C+11VERAPAMIL
6 BLOOD BRAIN BARRIER 391125 30% 4% 339 Search BLOOD+BRAIN+BARRIER Search BLOOD+BRAIN+BARRIER
7 MULTIDRUG TRANSPORTER 341143 3% 33% 38 Search MULTIDRUG+TRANSPORTER Search MULTIDRUG+TRANSPORTER
8 C 11TARIQUIDAR 164454 1% 100% 6 Search C+11TARIQUIDAR Search C+11TARIQUIDAR
9 BREAST CANCER RESISTANCE PROTEIN 154669 3% 16% 35 Search BREAST+CANCER+RESISTANCE+PROTEIN Search BREAST+CANCER+RESISTANCE+PROTEIN
10 ABCB1 150984 5% 9% 61 Search ABCB1 Search ABCB1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 FELDMANN, M , KOEPP, M , (2016) ABC TRANSPORTERS AND DRUG RESISTANCE IN PATIENTS WITH EPILEPSY.CURRENT PHARMACEUTICAL DESIGN. VOL. 22. ISSUE 38. P. 5793 -5807 101 63% 0
2 ARONICA, E , SISODIYA, SM , GORTER, JA , (2012) CEREBRAL EXPRESSION OF DRUG TRANSPORTERS IN EPILEPSY.ADVANCED DRUG DELIVERY REVIEWS. VOL. 64. ISSUE 10. P. 919 -929 99 56% 37
3 QOSA, H , MILLER, DS , PASINELLI, P , TROTTI, D , (2015) REGULATION OF ABC EFFLUX TRANSPORTERS AT BLOOD-BRAIN BARRIER IN HEALTH AND NEUROLOGICAL DISORDERS.BRAIN RESEARCH. VOL. 1628. ISSUE . P. 298 -316 95 50% 11
4 ZHANG, CB , KWAN, P , ZUO, Z , BAUM, L , (2012) THE TRANSPORT OF ANTIEPILEPTIC DRUGS BY P-GLYCOPROTEIN.ADVANCED DRUG DELIVERY REVIEWS. VOL. 64. ISSUE 10. P. 930-942 77 63% 50
5 POTSCHKA, H , (2010) TRANSPORTER HYPOTHESIS OF DRUG-RESISTANT EPILEPSY: CHALLENGES FOR PHARMACOGENETIC APPROACHES.PHARMACOGENOMICS. VOL. 11. ISSUE 10. P. 1427-1438 66 90% 9
6 CHOUCHI, M , KAABACHI, W , KLAA, H , TIZAOUI, K , TURKI, IBY , HILA, L , (2017) RELATIONSHIP BETWEEN ABCB1 3435TT GENOTYPE AND ANTIEPILEPTIC DRUGS RESISTANCE IN EPILEPSY: UPDATED SYSTEMATIC REVIEW AND META-ANALYSIS.BMC NEUROLOGY. VOL. 17. ISSUE . P. 1 -14 70 74% 0
7 POTSCHKA, H , LUNA-MUNGUIA, H , (2014) CNS TRANSPORTERS AND DRUG DELIVERY IN EPILEPSY.CURRENT PHARMACEUTICAL DESIGN. VOL. 20. ISSUE 10. P. 1534-1542 67 76% 7
8 SYVANEN, S , ERIKSSON, J , (2013) ADVANCES IN PET IMAGING OF P-GLYCOPROTEIN FUNCTION AT THE BLOOD-BRAIN BARRIER.ACS CHEMICAL NEUROSCIENCE. VOL. 4. ISSUE 2. P. 225-237 69 68% 19
9 HARTZ, AMS , BAUER, B , (2011) ABC TRANSPORTERS IN THE CNS - AN INVENTORY.CURRENT PHARMACEUTICAL BIOTECHNOLOGY. VOL. 12. ISSUE 4. P. 656-673 97 43% 33
10 LOSCHER, W , LUNA-TORTOS, C , ROMERMANN, K , FEDROWITZ, M , (2011) DO ATP-BINDING CASSETTE TRANSPORTERS CAUSE PHARMACORESISTANCE IN EPILEPSY? PROBLEMS AND APPROACHES IN DETERMINING WHICH ANTIEPILEPTIC DRUGS ARE AFFECTED.CURRENT PHARMACEUTICAL DESIGN. VOL. 17. ISSUE 26. P. 2808-2828 70 57% 40

Classes with closest relation at Level 1


Rank Class id link
1 20325 LOGBB//BLOOD BRAIN PARTITIONING//PAMPA BBB
2 9334 ABCG2//BCRP//BREAST CANCER RESISTANCE PROTEIN
3 37593 LOPERAMIDE//LOPERAMIDE HYDROCHLORIDE//DESMETHYLLOPERAMIDE
4 4989 BLOOD BRAIN BARRIER//BBB//TIGHT JUNCTION
5 5907 CYP3A5//ABCB1//MDR1
6 4059 P GLYCOPROTEIN//MULTIDRUG RESISTANCE//LMRA
7 4616 MRP1//MULTIDRUG RESISTANCE ASSOCIATED PROTEIN//MULTIDRUG RESISTANCE PROTEIN
8 30937 INNER BLOOD RETINAL BARRIER//PROTON COUPLED ORGANIC CATION ANTIPORTER//RETINAL CAPILLARY ENDOTHELIAL CELLS
9 5456 OATP1B1//SLCO1B1//OATP
10 34850 CEFADROXIL INTESTINAL ABSORPTION//CAS 50370 12 2//QUINOLONE ANTIMICROBIAL AGENT

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