Class information for: |
Basic class information |
Class id | #P | Avg. number of references |
Database coverage of references |
---|---|---|---|
4059 | 1855 | 49.0 | 89% |
Hierarchy of classes |
The table includes all classes above and classes immediately below the current class. |
Cluster id | Level | Cluster label | #P |
---|---|---|---|
0 | 4 | BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY | 4064930 |
230 | 3 | P GLYCOPROTEIN//FMO3//TRIMETHYLAMINURIA | 49374 |
747 | 2 | P GLYCOPROTEIN//MULTIDRUG RESISTANCE//MDR1 | 12474 |
4059 | 1 | P GLYCOPROTEIN//MULTIDRUG RESISTANCE//LMRA | 1855 |
Terms with highest relevance score |
rank | Term | termType | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|---|
1 | P GLYCOPROTEIN | authKW | 834130 | 28% | 10% | 527 |
2 | MULTIDRUG RESISTANCE | authKW | 443615 | 21% | 7% | 397 |
3 | LMRA | authKW | 206807 | 1% | 74% | 17 |
4 | ABC TRANSPORTER | authKW | 201165 | 7% | 10% | 128 |
5 | MDR MODULATORS | authKW | 156831 | 1% | 53% | 18 |
6 | HZ08 | authKW | 121197 | 0% | 82% | 9 |
7 | MSBA | authKW | 118498 | 1% | 60% | 12 |
8 | NUCLEOTIDE BINDING DOMAIN | authKW | 110577 | 1% | 27% | 25 |
9 | GRP MEMBRANE BIOL | address | 101186 | 1% | 36% | 17 |
10 | KB C2 CELL | authKW | 82297 | 0% | 100% | 5 |
Web of Science journal categories |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | Biochemistry & Molecular Biology | 6284 | 49% | 0% | 904 |
2 | Chemistry, Medicinal | 4635 | 15% | 0% | 284 |
3 | Pharmacology & Pharmacy | 2904 | 25% | 0% | 458 |
4 | Biophysics | 2166 | 13% | 0% | 245 |
5 | Oncology | 333 | 9% | 0% | 167 |
6 | Cell Biology | 322 | 9% | 0% | 162 |
7 | Biochemical Research Methods | 102 | 3% | 0% | 64 |
8 | Mathematical & Computational Biology | 65 | 1% | 0% | 26 |
9 | Computer Science, Interdisciplinary Applications | 56 | 2% | 0% | 40 |
10 | Chemistry, Multidisciplinary | 35 | 6% | 0% | 114 |
Address terms |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | GRP MEMBRANE BIOL | 101186 | 1% | 36% | 17 |
2 | CANADIAN HLTH GRP MEMBRANE BIOL | 75236 | 0% | 57% | 8 |
3 | PHYSICOCHIM BIOMOL CELLULAIRE | 53499 | 1% | 17% | 19 |
4 | QUIM MED CEQUIMED UP | 52668 | 0% | 80% | 4 |
5 | BIO N210 | 39495 | 0% | 40% | 6 |
6 | UP A 7033 | 34285 | 0% | 42% | 5 |
7 | BIOCHIM STRUCT FONCT | 32919 | 0% | 100% | 2 |
8 | DRDC BIOPHYS MOL CELLULAIRE | 32919 | 0% | 100% | 2 |
9 | LEHRSTUHL TECH MIKROBIOL WEIHENSTEPHAN | 32919 | 0% | 100% | 2 |
10 | NAN JING DEV | 32919 | 0% | 100% | 2 |
Journals |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
---|---|---|---|---|---|
1 | BIOCHEMISTRY | 6336 | 8% | 0% | 145 |
2 | JOURNAL OF BIOLOGICAL CHEMISTRY | 3272 | 10% | 0% | 179 |
3 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 3177 | 2% | 1% | 35 |
4 | MOLECULAR PHARMACOLOGY | 2129 | 2% | 0% | 36 |
5 | JOURNAL OF BIOENERGETICS AND BIOMEMBRANES | 1916 | 1% | 1% | 15 |
6 | JOURNAL OF MEDICINAL CHEMISTRY | 1692 | 3% | 0% | 48 |
7 | EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES | 1656 | 1% | 1% | 19 |
8 | BIOORGANIC & MEDICINAL CHEMISTRY | 1409 | 2% | 0% | 34 |
9 | BIOCHEMICAL PHARMACOLOGY | 1361 | 2% | 0% | 40 |
10 | DRUG RESISTANCE UPDATES | 1212 | 0% | 1% | 6 |
Author Key Words |
Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
LCSH search | Wikipedia search |
---|---|---|---|---|---|---|---|
1 | P GLYCOPROTEIN | 834130 | 28% | 10% | 527 | Search P+GLYCOPROTEIN | Search P+GLYCOPROTEIN |
2 | MULTIDRUG RESISTANCE | 443615 | 21% | 7% | 397 | Search MULTIDRUG+RESISTANCE | Search MULTIDRUG+RESISTANCE |
3 | LMRA | 206807 | 1% | 74% | 17 | Search LMRA | Search LMRA |
4 | ABC TRANSPORTER | 201165 | 7% | 10% | 128 | Search ABC+TRANSPORTER | Search ABC+TRANSPORTER |
5 | MDR MODULATORS | 156831 | 1% | 53% | 18 | Search MDR+MODULATORS | Search MDR+MODULATORS |
6 | HZ08 | 121197 | 0% | 82% | 9 | Search HZ08 | Search HZ08 |
7 | MSBA | 118498 | 1% | 60% | 12 | Search MSBA | Search MSBA |
8 | NUCLEOTIDE BINDING DOMAIN | 110577 | 1% | 27% | 25 | Search NUCLEOTIDE+BINDING+DOMAIN | Search NUCLEOTIDE+BINDING+DOMAIN |
9 | KB C2 CELL | 82297 | 0% | 100% | 5 | Search KB+C2+CELL | Search KB+C2+CELL |
10 | N N BISCYCLOHEXANOLAMINE ARYL ESTERS | 82297 | 0% | 100% | 5 | Search N+N+BISCYCLOHEXANOLAMINE+ARYL+ESTERS | Search N+N+BISCYCLOHEXANOLAMINE+ARYL+ESTERS |
Core articles |
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c: (1) Number of references referring to publications in the class. (2) Share of total number of active references referring to publications in the class. (3) Age of the article. New articles get higher score than old articles. (4) Citation rate, normalized to year. |
Rank | Reference | # ref. in cl. |
Shr. of ref. in cl. |
Citations |
---|---|---|---|---|
1 | FERREIRA, RJ , FERREIRA, MJU , DOS SANTOS, DJVA , (2015) REVERSING CANCER MULTIDRUG RESISTANCE: INSIGHTS INTO THE EFFLUX BY ABC TRANSPORTS FROM IN SILICO STUDIES.WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE. VOL. 5. ISSUE 1. P. 27 -55 | 126 | 69% | 5 |
2 | ECKFORD, PDW , SHAROM, FJ , (2009) ABC EFFLUX PUMP-BASED RESISTANCE TO CHEMOTHERAPY DRUGS.CHEMICAL REVIEWS. VOL. 109. ISSUE 7. P. 2989-3011 | 146 | 48% | 236 |
3 | HENNESSY, M , SPIERS, JP , (2007) A PRIMER ON THE MECHANICS OF P-GLYCOPROTEIN THE MULTIDRUG TRANSPORTER.PHARMACOLOGICAL RESEARCH. VOL. 55. ISSUE 1. P. 1-15 | 126 | 68% | 103 |
4 | SHAROM, FJ , (2006) SHEDDING LIGHT ON DRUG TRANSPORT: STRUCTURE AND FUNCTION OF THE P-GLYCOPROTEIN MULTIDRUG TRANSPORTER (ABCB1).BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE. VOL. 84. ISSUE 6. P. 979 -992 | 110 | 87% | 52 |
5 | SEEGER, MA , VAN VEEN, HW , (2009) MOLECULAR BASIS OF MULTIDRUG TRANSPORT BY ABC TRANSPORTERS.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1794. ISSUE 5. P. 725 -737 | 101 | 78% | 75 |
6 | AMBUDKAR, SV , DEY, S , HRYCYNA, CA , RAMACHANDRA, M , PASTAN, I , GOTTESMAN, MM , (1999) BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTER.ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. VOL. 39. ISSUE . P. 361 -398 | 92 | 58% | 1365 |
7 | LOO, TW , CLARKE, DM , (2005) RECENT PROGRESS IN UNDERSTANDING THE MECHANISM OF P-GLYCOPROTEIN-MEDIATED DRUG EFFLUX.JOURNAL OF MEMBRANE BIOLOGY. VOL. 206. ISSUE 3. P. 173-185 | 108 | 78% | 127 |
8 | PRAJAPATI, R , SANGAMWAR, AT , (2014) TRANSLOCATION MECHANISM OF P-GLYCOPROTEIN AND CONFORMATIONAL CHANGES OCCURRING AT DRUG-BINDING SITE: INSIGHTS FROM MULTI-TARGETED MOLECULAR DYNAMICS.BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. VOL. 1838. ISSUE 11. P. 2882 -2898 | 70 | 95% | 10 |
9 | GEORGE, AM , JONES, PM , (2012) PERSPECTIVES ON THE STRUCTURE-FUNCTION OF ABC TRANSPORTERS: THE SWITCH AND CONSTANT CONTACT MODELS.PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY. VOL. 109. ISSUE 3. P. 95 -107 | 90 | 69% | 41 |
10 | LAWSON, J , O'MARA, ML , KERR, ID , (2008) STRUCTURE-BASED INTERPRETATION OF THE MUTAGENESIS DATABASE FOR THE NUCLEOTIDE BINDING DOMAINS OF P-GLYCOPROTEIN.BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. VOL. 1778. ISSUE 2. P. 376-391 | 86 | 81% | 20 |
Classes with closest relation at Level 1 |