Class information for:
Level 1: CEFADROXIL INTESTINAL ABSORPTION//CAS 50370 12 2//QUINOLONE ANTIMICROBIAL AGENT

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
34850 105 26.1 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
230 3       P GLYCOPROTEIN//FMO3//TRIMETHYLAMINURIA 49374
1155 2             PEPT1//ORGANIC CATION TRANSPORTER//OATP1B1 9490
34850 1                   CEFADROXIL INTESTINAL ABSORPTION//CAS 50370 12 2//QUINOLONE ANTIMICROBIAL AGENT 105

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CEFADROXIL INTESTINAL ABSORPTION authKW 872446 3% 100% 3
2 CAS 50370 12 2 authKW 654333 3% 75% 3
3 QUINOLONE ANTIMICROBIAL AGENT authKW 654333 3% 75% 3
4 ABSORPTION PARTITION CORRELATION authKW 581631 2% 100% 2
5 CAS 151 21 3 authKW 581631 2% 100% 2
6 ORAL BIOAVAILABILITY PREDICTION authKW 581631 2% 100% 2
7 SODIUM LAURYL SULFATE EFFECT ON INTESTINAL DRUG ABSORPTION authKW 581631 2% 100% 2
8 STAGNANT DIFFUSION LAYER authKW 581631 2% 100% 2
9 SURFACTANTS ANIONIC authKW 581631 2% 100% 2
10 ABSORPTION LIPOPHILICITY APPROACH authKW 290815 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 2616 90% 0% 94
2 Chemistry, Medicinal 227 14% 0% 15
3 Microbiology 75 12% 0% 13
4 Chemistry, Multidisciplinary 62 18% 0% 19
5 Infectious Diseases 19 5% 0% 5
6 Substance Abuse 14 2% 0% 2
7 Toxicology 1 2% 0% 2
8 Mathematical & Computational Biology 1 1% 0% 1
9 Veterinary Sciences 0 2% 0% 2
10 Biophysics 0 2% 0% 2

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARM PHARMCEUT 290815 1% 100% 1
2 UNIT EXPT BACTERIOL 290815 1% 100% 1
3 UP PASSAGE MEMBRANAIRE MEDICAMENTS 290815 1% 100% 1
4 UNITE NUTR HUMAINE PHYSIOL INTESTINALE 89478 2% 15% 2
5 SERV PHARM CLIN BIOMAT 61221 2% 11% 2
6 AREA FARM TECNOL FARMACEUT 48468 1% 17% 1
7 PHARM PHARMACEUT 28364 4% 2% 4
8 SAFETY ASSESSMENT TRADIT CHINESE MED 26436 1% 9% 1
9 HOSP PHARM PHARMACOKINET 24233 1% 8% 1
10 PHARMACOBIODYNAM 24231 2% 4% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOPHARMACEUTICS & DRUG DISPOSITION 7396 7% 0% 7
2 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 6323 4% 1% 4
3 INTERNATIONAL JOURNAL OF PHARMACEUTICS 4706 15% 0% 16
4 JOURNAL OF PHARMACEUTICAL SCIENCES 2593 10% 0% 10
5 AAPS PHARMSCI 1660 1% 1% 1
6 ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH 1242 3% 0% 3
7 ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 989 9% 0% 9
8 PHARMACEUTICAL RESEARCH 904 5% 0% 5
9 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 878 8% 0% 8
10 JOURNAL OF DRUG TARGETING 745 2% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CEFADROXIL INTESTINAL ABSORPTION 872446 3% 100% 3 Search CEFADROXIL+INTESTINAL+ABSORPTION Search CEFADROXIL+INTESTINAL+ABSORPTION
2 CAS 50370 12 2 654333 3% 75% 3 Search CAS+50370+12+2 Search CAS+50370+12+2
3 QUINOLONE ANTIMICROBIAL AGENT 654333 3% 75% 3 Search QUINOLONE+ANTIMICROBIAL+AGENT Search QUINOLONE+ANTIMICROBIAL+AGENT
4 ABSORPTION PARTITION CORRELATION 581631 2% 100% 2 Search ABSORPTION+PARTITION+CORRELATION Search ABSORPTION+PARTITION+CORRELATION
5 CAS 151 21 3 581631 2% 100% 2 Search CAS+151+21+3 Search CAS+151+21+3
6 ORAL BIOAVAILABILITY PREDICTION 581631 2% 100% 2 Search ORAL+BIOAVAILABILITY+PREDICTION Search ORAL+BIOAVAILABILITY+PREDICTION
7 SODIUM LAURYL SULFATE EFFECT ON INTESTINAL DRUG ABSORPTION 581631 2% 100% 2 Search SODIUM+LAURYL+SULFATE+EFFECT+ON+INTESTINAL+DRUG+ABSORPTION Search SODIUM+LAURYL+SULFATE+EFFECT+ON+INTESTINAL+DRUG+ABSORPTION
8 STAGNANT DIFFUSION LAYER 581631 2% 100% 2 Search STAGNANT+DIFFUSION+LAYER Search STAGNANT+DIFFUSION+LAYER
9 SURFACTANTS ANIONIC 581631 2% 100% 2 Search SURFACTANTS+ANIONIC Search SURFACTANTS+ANIONIC
10 ABSORPTION LIPOPHILICITY APPROACH 290815 1% 100% 1 Search ABSORPTION+LIPOPHILICITY+APPROACH Search ABSORPTION+LIPOPHILICITY+APPROACH

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 FERNANDEZ-TERUEL, C , GONZALEZ-ALVAREZ, I , CASABO, VG , RUIZ-GARCIA, A , BERMEJO, M , (2005) KINETIC MODELLING OF THE INTESTINAL TRANSPORT OF SARAFLOXACIN. STUDIES IN SITU IN RAT AND IN VITRO IN CACO-2 CELLS.JOURNAL OF DRUG TARGETING. VOL. 13. ISSUE 3. P. 199-212 21 53% 15
2 FERNANDEZ-TERUEL, C , MANGAS-SANJUAN, V , GONZALEZ-ALVAREZ, I , RUIZ-GARCIA, A , CASABO, VG , BERMEJO, M , (2013) MATHEMATICAL MODELING OF ORAL ABSORPTION AND BIOAVAILABILITY OF A FLUOROQUINOLONE AFTER ITS PRECIPITATION IN THE GASTROINTESTINAL TRACT.XENOBIOTICA. VOL. 43. ISSUE 9. P. 745-754 14 58% 1
3 RODRIGUEZ-IBANEZ, M , SANCHEZ-CASTANO, G , MONTALAR-MONTERO, M , GARRIGUES, TM , BERMEJO, M , MERINO, V , (2006) MATHEMATICAL MODELLING OF IN SITU AND IN VITRO EFFLUX OF CIPROFLOXACIN AND GREPAFLOXACIN.INTERNATIONAL JOURNAL OF PHARMACEUTICS. VOL. 307. ISSUE 1. P. 33-41 18 47% 5
4 FABRACAMPOS, S , CLIMENT, E , SANCHISCORTES, A , PLADELFINA, JM , (1994) COMPARED EFFECTS OF SYNTHETIC AND NATURAL BILE-ACID SURFACTANTS ON XENOBIOTIC ABSORPTION .4. STUDIES WITH TAUROCHOLATE IN THE RAT SMALL-INTESTINE.INTERNATIONAL JOURNAL OF PHARMACEUTICS. VOL. 109. ISSUE 3. P. 197-207 11 92% 6
5 PEREZBUENDIA, MD , GOMEZPEREZ, B , PLADELFINA, JM , (1993) PERMEATION MECHANISMS THROUGH ARTIFICIAL LIPOIDAL MEMBRANES AND EFFECTS OF SYNTHETIC SURFACTANTS ON XENOBIOTIC PERMEABILITY.ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH. VOL. 43-2. ISSUE 7. P. 789-794 11 79% 4
6 MARTINEZCOSCOLLA, A , MIRALLESLOYOLA, E , GARRIGUES, TM , SIRVENT, MD , SALINAS, E , CASABO, VG , (1993) STUDIES ON THE RELIABILITY OF A NOVEL ABSORPTION-LIPOPHILICITY APPROACH TO INTERPRET THE EFFECTS OF THE SYNTHETIC SURFACTANTS ON DRUG AND XENOBIOTIC ABSORPTION.ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH. VOL. 43-1. ISSUE 6. P. 699-705 10 83% 11
7 MONTALAR, M , NALDA-MOLINA, R , RODRIGUEZ-IBANEZ, M , GARCIA-VALCARCEL, I , GARRIGUES, TM , MERINO, V , BERMEJO, M , (2003) KINETIC MODELING OF TRIAMTERENE INTESTINAL ABSORPTION AND ITS INHIBITION BY FOLIC ACID AND METHOTREXATE.JOURNAL OF DRUG TARGETING. VOL. 11. ISSUE 4. P. 215-223 12 46% 4
8 MARTINALGARRA, RV , PASCUALCOSTA, RM , MERINO, M , CASABO, VG , (1995) EFFECTS OF POLYSORBATE-80 ON AMIODARONE INTESTINAL-ABSORPTION IN THE RAT.INTERNATIONAL JOURNAL OF PHARMACEUTICS. VOL. 122. ISSUE 1-2. P. 1-8 8 80% 5
9 GARRIGUES, TM , PEREZVARONA, AT , BERMEJO, MV , MARTINVILLODRE, A , (1992) ABSORPTION-PARTITION RELATIONSHIPS FOR TRUE HOMOLOGOUS SERIES OF XENOBIOTICS AS A POSSIBLE APPROACH TO STUDY MECHANISMS OF SURFACTANTS IN ABSORPTION .4. PHENYLACETIC ACID-DERIVATIVES AND ANIONIC SURFACTANTS.INTERNATIONAL JOURNAL OF PHARMACEUTICS. VOL. 79. ISSUE 2-3. P. 135-140 8 89% 2
10 ALVAREZ, AI , PEREZ, M , PRIETO, JG , MOLINA, AJ , REAL, R , MERINO, G , (2008) FLUOROQUINOLONE EFFLUX MEDIATED BY ABC TRANSPORTERS.JOURNAL OF PHARMACEUTICAL SCIENCES. VOL. 97. ISSUE 9. P. 3483-3493 15 22% 36

Classes with closest relation at Level 1


Rank Class id link
1 1901 BIOPHARMACEUTICS CLASSIFICATION SYSTEM//ORAL ABSORPTION//CACO 2
2 7903 PEPT1//PEPT2//PEPTIDE TRANSPORTER
3 15405 MARBOFLOXACIN//ENROFLOXACIN//DANOFLOXACIN
4 13319 INTERACTION WITH CALF THYMUS DNA//NORFLOXACIN//AGR FOOD TECHNOL NUTR
5 1143 JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY//ANTIMICROBIAL AGENTS AND CHEMOTHERAPY//FLEROXACIN
6 35043 ALKYLPHENOL ETHYLENE OXIDE SURFACTANTS//CHLORHEXIDINE PHOSPHATIDYLCHOLINE NONIONIC TENZIDE COMPLEX//CYCLODEXTRIN INTERACTION
7 14170 ANTOFLOXACIN HYDROCHLORIDE//ANTOFLOXACIN//HOIGNES SYNDROME
8 4616 MRP1//MULTIDRUG RESISTANCE ASSOCIATED PROTEIN//MULTIDRUG RESISTANCE PROTEIN
9 27350 CHEMOTHERAPY-TOKYO//POLY VINYL PYROLIDONE//CIPROFLOXACIN TRIMETHOPRIM SYNERGISM
10 26970 MIZORIBINE//ORAL MIZORIBINE PULSE THERAPY//LS180 CELL

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