Class information for:
Level 1: MRP1//MULTIDRUG RESISTANCE ASSOCIATED PROTEIN//MULTIDRUG RESISTANCE PROTEIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4616 1755 48.2 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
230 3       P GLYCOPROTEIN//FMO3//TRIMETHYLAMINURIA 49374
747 2             P GLYCOPROTEIN//MULTIDRUG RESISTANCE//MDR1 12474
4616 1                   MRP1//MULTIDRUG RESISTANCE ASSOCIATED PROTEIN//MULTIDRUG RESISTANCE PROTEIN 1755

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MRP1 authKW 675495 6% 35% 112
2 MULTIDRUG RESISTANCE ASSOCIATED PROTEIN authKW 463863 5% 30% 89
3 MULTIDRUG RESISTANCE PROTEIN authKW 421343 4% 34% 72
4 MRP authKW 312027 5% 19% 93
5 MRP2 authKW 278815 4% 24% 67
6 DUBIN JOHNSON SYNDROME authKW 258805 2% 55% 27
7 TUMOR BIOCHEM address 196215 2% 28% 41
8 CANC S address 171299 3% 18% 54
9 MRP4 authKW 164716 1% 38% 25
10 ABCC2 authKW 157608 2% 28% 32

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 4142 30% 0% 520
2 Oncology 3066 23% 0% 403
3 Biochemistry & Molecular Biology 1246 25% 0% 444
4 Biophysics 506 7% 0% 126
5 Gastroenterology & Hepatology 344 5% 0% 88
6 Toxicology 336 5% 0% 86
7 Cell Biology 214 8% 0% 135
8 Medicine, Research & Experimental 101 4% 0% 71
9 Chemistry, Medicinal 80 3% 0% 49
10 Genetics & Heredity 78 4% 0% 75

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TUMOR BIOCHEM 196215 2% 28% 41
2 CANC S 171299 3% 18% 54
3 SC JOHNSON MED 52483 1% 23% 13
4 CANC BIOL GENET 45987 3% 6% 46
5 U456 25996 1% 12% 13
6 NZ EYE 23195 0% 67% 2
7 REFERENCE MALAD INFLAMMATOI FOIE VO 23195 0% 67% 2
8 WALTHER ONCOL WALTHER CANC 22365 0% 43% 3
9 BILL WALSH CANC S 19562 0% 19% 6
10 FISIOL EXPT 19399 1% 9% 12

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DRUG METABOLISM AND DISPOSITION 7454 3% 1% 57
2 MOLECULAR PHARMACOLOGY 3871 3% 0% 47
3 PHARMACOGENETICS AND GENOMICS 3425 1% 1% 15
4 BIOCHEMICAL PHARMACOLOGY 2872 3% 0% 56
5 DRUG METABOLISM AND PHARMACOKINETICS 1937 1% 1% 9
6 PHARMACOGENOMICS JOURNAL 1768 1% 1% 9
7 DRUG METABOLISM REVIEWS 1400 1% 1% 9
8 BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1312 1% 0% 22
9 CANCER RESEARCH 1217 3% 0% 54
10 PHARMACEUTICAL RESEARCH 1212 1% 0% 24

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MRP1 675495 6% 35% 112 Search MRP1 Search MRP1
2 MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 463863 5% 30% 89 Search MULTIDRUG+RESISTANCE+ASSOCIATED+PROTEIN Search MULTIDRUG+RESISTANCE+ASSOCIATED+PROTEIN
3 MULTIDRUG RESISTANCE PROTEIN 421343 4% 34% 72 Search MULTIDRUG+RESISTANCE+PROTEIN Search MULTIDRUG+RESISTANCE+PROTEIN
4 MRP 312027 5% 19% 93 Search MRP Search MRP
5 MRP2 278815 4% 24% 67 Search MRP2 Search MRP2
6 DUBIN JOHNSON SYNDROME 258805 2% 55% 27 Search DUBIN+JOHNSON+SYNDROME Search DUBIN+JOHNSON+SYNDROME
7 MRP4 164716 1% 38% 25 Search MRP4 Search MRP4
8 ABCC2 157608 2% 28% 32 Search ABCC2 Search ABCC2
9 GS X PUMP 154736 1% 68% 13 Search GS+X+PUMP Search GS+X+PUMP
10 CMOAT 153562 1% 55% 16 Search CMOAT Search CMOAT

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 DEELEY, RG , WESTLAKE, C , COLE, SPC , (2006) TRANSMEMBRANE TRANSPORT OF ENDO- AND XENOBIOTICS BY MAMMALIAN ATP-BINDING CASSETTE MULTIDRUG RESISTANCE PROTEINS.PHYSIOLOGICAL REVIEWS. VOL. 86. ISSUE 3. P. 849-899 297 54% 393
2 HAIMEUR, A , CONSEIL, G , DEELEY, RG , COLE, SPC , (2004) THE MRP-RELATED AND BCRP/ABCG2 MULTIDRUG RESISTANCE PROTEINS: BIOLOGY, SUBSTRATE SPECIFICITY AND REGULATION.CURRENT DRUG METABOLISM. VOL. 5. ISSUE 1. P. 21-53 260 64% 331
3 HE, SM , LI, R , KANWAR, JR , ZHOU, SF , (2011) STRUCTURAL AND FUNCTIONAL PROPERTIES OF HUMAN MULTIDRUG RESISTANCE PROTEIN 1 (MRP1/ABCC1).CURRENT MEDICINAL CHEMISTRY. VOL. 18. ISSUE 3. P. 439 -481 268 61% 42
4 ZHOU, SF , WANG, LL , DI, YM , XUE, CC , DUAN, W , LI, CG , LI, Y , (2008) SUBSTRATES AND INHIBITORS OF HUMAN MULTIDRUG RESISTANCE ASSOCIATED PROTEINS AND THE IMPLICATIONS IN DRUG DEVELOPMENT.CURRENT MEDICINAL CHEMISTRY. VOL. 15. ISSUE 20. P. 1981-2039 233 51% 169
5 CHEN, ZS , TIWARI, AK , (2011) MULTIDRUG RESISTANCE PROTEINS (MRPS/ABCCS) IN CANCER CHEMOTHERAPY AND GENETIC DISEASES.FEBS JOURNAL. VOL. 278. ISSUE 18. P. 3226 -3245 142 76% 84
6 BAKOS, E , HOMOLYA, L , (2007) PORTRAIT OF MULTIFACETED TRANSPORTER, THE MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1 (MRP1/ABCC1).PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 453. ISSUE 5. P. 621-641 142 78% 80
7 KRUH, GD , BELINSKY, MG , (2003) THE MRP FAMILY OF DRUG EFFLUX PUMPS.ONCOGENE. VOL. 22. ISSUE 47. P. 7537-7552 131 72% 389
8 SODANI, K , PATEL, A , KATHAWALA, RJ , CHEN, ZS , (2012) MULTIDRUG RESISTANCE ASSOCIATED PROTEINS IN MULTIDRUG RESISTANCE.CHINESE JOURNAL OF CANCER. VOL. 31. ISSUE 2. P. 58-72 131 72% 22
9 CHANG, XB , (2007) A MOLECULAR UNDERSTANDING OF ATP-DEPENDENT SOLUTE TRANSPORT BY MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN MRP1.CANCER AND METASTASIS REVIEWS. VOL. 26. ISSUE 1. P. 15-37 151 61% 32
10 TIAN, Q , ZHANG, J , CHAN, E , DUAN, W , ZHOU, SF , (2005) MULTIDRUG RESISTANCE PROTEINS (MRPS) AND IMPLICATION IN DRUG DEVELOPMENT.DRUG DEVELOPMENT RESEARCH. VOL. 64. ISSUE 1. P. 1 -18 134 72% 12

Classes with closest relation at Level 1


Rank Class id link
1 9334 ABCG2//BCRP//BREAST CANCER RESISTANCE PROTEIN
2 24945 MULTIXENOBIOTIC RESISTANCE//MXR//MOL ECOTOXICOL
3 4059 P GLYCOPROTEIN//MULTIDRUG RESISTANCE//LMRA
4 25795 MAJOR VAULT PROTEIN//VAULT//VPARP
5 5456 OATP1B1//SLCO1B1//OATP
6 216 MULTIDRUG RESISTANCE//P GLYCOPROTEIN//PSC 833
7 3044 ORGANIC ANIONS//CANALICULAR MEMBRANE//BILITRANSLOCASE
8 9862 P GLYCOPROTEIN//PHARMACORESISTANCE//TARIQUIDAR
9 33937 ROTOR SYNDROME//BLUE DIVISION//DUBIN JOHNSON
10 34850 CEFADROXIL INTESTINAL ABSORPTION//CAS 50370 12 2//QUINOLONE ANTIMICROBIAL AGENT

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