Class information for:
Level 1: LOPERAMIDE//LOPERAMIDE HYDROCHLORIDE//DESMETHYLLOPERAMIDE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
37593 53 19.7 56%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
587 3       DECOMPRESSION SICKNESS//HIGH ALTITUDE MEDICINE & BIOLOGY//ACUTE MOUNTAIN SICKNESS 15311
3113 2             JOURNAL OF TRAVEL MEDICINE//HYDROTROPY//HYDROTROPES 2303
37593 1                   LOPERAMIDE//LOPERAMIDE HYDROCHLORIDE//DESMETHYLLOPERAMIDE 53

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LOPERAMIDE authKW 1201919 42% 9% 22
2 LOPERAMIDE HYDROCHLORIDE authKW 1024255 8% 44% 4
3 DESMETHYLLOPERAMIDE authKW 576146 2% 100% 1
4 IATRONIC DISEASES authKW 576146 2% 100% 1
5 ILLICIT OPIOD USE authKW 576146 2% 100% 1
6 INTERNAL MED 6CLIN PHARMACOL PHARMACOEPID address 576146 2% 100% 1
7 LEGAL TRAFFIC MED address 576146 2% 100% 1
8 LOPERAMID HYDROCHLORIDE authKW 576146 2% 100% 1
9 LOPERAMIDE AND METABOLITES authKW 576146 2% 100% 1
10 N DEMETHYL LOPERAMIDE authKW 576146 2% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Analytical 221 28% 0% 15
2 Pharmacology & Pharmacy 190 36% 0% 19
3 Toxicology 68 11% 0% 6
4 Emergency Medicine 38 4% 0% 2
5 Biochemical Research Methods 35 9% 0% 5
6 Psychiatry 17 8% 0% 4
7 Medicine, Legal 15 2% 0% 1
8 Substance Abuse 7 2% 0% 1
9 Gastroenterology & Hepatology 5 4% 0% 2
10 Veterinary Sciences 3 4% 0% 2

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTERNAL MED 6CLIN PHARMACOL PHARMACOEPID 576146 2% 100% 1
2 LEGAL TRAFFIC MED 576146 2% 100% 1
3 BIOHLTH CONVERGENCE 288072 2% 50% 1
4 RUTH A LAWRENCE POISON DRUG INFORMAT 288072 2% 50% 1
5 LEAD GENERAT COMPOUND REALIZAT 144035 2% 25% 1
6 OHIO EXCELLENCE KNOWLEDGE ENABLED COMP KNO E 57613 2% 10% 1
7 JEDDAH COMMUNITY 17457 2% 3% 1
8 RONALD O PERELMAN EMERGENCY MED 12523 2% 2% 1
9 SAN DIEGO 9763 2% 2% 1
10 INTERVENT TREATMENT ADDICT 8000 2% 1% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 REVIEWS IN GASTROENTEROLOGICAL DISORDERS 33887 4% 3% 2
2 APPLIED BIOLOGICAL CHEMISTRY 5538 2% 1% 1
3 CLINICAL TOXICOLOGY 1548 4% 0% 2
4 VETERINARY AND HUMAN TOXICOLOGY 1059 4% 0% 2
5 PSYCHIATRIC QUARTERLY 848 2% 0% 1
6 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 840 8% 0% 4
7 HEMIJSKA INDUSTRIJA 795 2% 0% 1
8 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 766 8% 0% 4
9 JOURNAL OF PHARMACOLOGICAL METHODS 742 2% 0% 1
10 JOURNAL OF ANALYTICAL TOXICOLOGY 690 4% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LOPERAMIDE 1201919 42% 9% 22 Search LOPERAMIDE Search LOPERAMIDE
2 LOPERAMIDE HYDROCHLORIDE 1024255 8% 44% 4 Search LOPERAMIDE+HYDROCHLORIDE Search LOPERAMIDE+HYDROCHLORIDE
3 DESMETHYLLOPERAMIDE 576146 2% 100% 1 Search DESMETHYLLOPERAMIDE Search DESMETHYLLOPERAMIDE
4 IATRONIC DISEASES 576146 2% 100% 1 Search IATRONIC+DISEASES Search IATRONIC+DISEASES
5 ILLICIT OPIOD USE 576146 2% 100% 1 Search ILLICIT+OPIOD+USE Search ILLICIT+OPIOD+USE
6 LOPERAMID HYDROCHLORIDE 576146 2% 100% 1 Search LOPERAMID+HYDROCHLORIDE Search LOPERAMID+HYDROCHLORIDE
7 LOPERAMIDE AND METABOLITES 576146 2% 100% 1 Search LOPERAMIDE+AND+METABOLITES Search LOPERAMIDE+AND+METABOLITES
8 N DEMETHYL LOPERAMIDE 576146 2% 100% 1 Search N+DEMETHYL+LOPERAMIDE Search N+DEMETHYL+LOPERAMIDE
9 NIMEDIPINE 576146 2% 100% 1 Search NIMEDIPINE Search NIMEDIPINE
10 ZNOALPHA FE2O3 COMPOSITES 576146 2% 100% 1 Search ZNOALPHA+FE2O3+COMPOSITES Search ZNOALPHA+FE2O3+COMPOSITES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 EGGLESTON, W , CLARK, KH , MARRAFFA, JM , (2017) LOPERAMIDE ABUSE ASSOCIATED WITH CARDIAC DYSRHYTHMIA AND DEATH.ANNALS OF EMERGENCY MEDICINE. VOL. 69. ISSUE 1. P. 83 -86 8 38% 4
2 LASOFF, DR , KOH, CH , CORBETT, B , MINNS, AB , CANTRELL, FL , (2017) LOPERAMIDE TRENDS IN ABUSE AND MISUSE OVER 13 YEARS: 2002-2015.PHARMACOTHERAPY. VOL. 37. ISSUE 2. P. 249 -253 7 78% 0
3 ARAFAT, T , ARAFAT, B , AWAD, R , ABU AWWAD, A , (2014) DETERMINATION OF LOPERAMIDE IN HUMAN PLASMA AND SALIVA BY LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 972. ISSUE . P. 81 -88 8 67% 3
4 VAKKALANKA, JP , CHARLTON, NP , HOLSTEGE, CR , (2017) EPIDEMIOLOGIC TRENDS IN LOPERAMIDE ABUSE AND MISUSE.ANNALS OF EMERGENCY MEDICINE. VOL. 69. ISSUE 1. P. 73 -78 6 50% 1
5 SKLEROV, J , LEVINE, B , MOORE, KA , ALLAN, C , FOWLER, D , (2005) TISSUE DISTRIBUTION OF LOPERAMIDE AND N-DESMETHYLLOPERAMIDE FOLLOWING A FATAL OVERDOSE.JOURNAL OF ANALYTICAL TOXICOLOGY. VOL. 29. ISSUE 7. P. 750-754 8 80% 7
6 YU, JH , KIM, HJ , LEE, S , HWANG, SJ , KIM, W , MOON, CJ , (2004) LC-MS DETERMINATION AND BIOAVAILABILITY STUDY OF LOPERAMIDE HYDROCHLORIDE AFTER ORAL ADMINISTRATION OF LOPERAMIDE CAPSULE IN HUMAN VOLUNTEERS.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. VOL. 36. ISSUE 2. P. 421-427 8 80% 6
7 DIERKSEN, J , GONSOULIN, M , WALTERSCHEID, JP , (2015) POOR MAN'S METHADONE A CASE REPORT OF LOPERAMIDE TOXICITY.AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY. VOL. 36. ISSUE 4. P. 268 -270 6 75% 4
8 SAVIC, IM , NIKOLIC, GS , SAVIC, IM , MARINKOVIC, VD , (2009) QUANTITATIVE ANALYSIS OF LOPERAMIDE HYDROCHLORIDE IN THE PRESENCE ITS ACID DEGRADATION PRODUCTS.HEMIJSKA INDUSTRIJA. VOL. 63. ISSUE 1. P. 39-46 7 78% 2
9 GANSSMANN, B , KLINGMANN, A , BURHENNE, J , TAYROUZ, Y , ADERJAN, R , MIKUS, G , (2001) SIMULTANEOUS DETERMINATION OF LOPERAMIDE AND ITS DESMETHYLATED METABOLITES IN PLASMA AND URINE BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY - ATMOSPHERIC PRESSURE IONIZATION MASS SPECTROMETRY.CHROMATOGRAPHIA. VOL. 53. ISSUE 11-12. P. 656-660 7 88% 6
10 EGGLESTON, W , MARRAFFA, JM , STORK, CM , MERCURIO-ZAPPALA, M , SU, MK , WIGHTMAN, RS , CUMMINGS, KR , SCHIER, JG , (2016) CARDIAC DYSRHYTHMIAS AFTER LOPERAMIDE ABUSE - NEW YORK, 2008-2016.MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT. VOL. 65. ISSUE 45. P. 1276 -1277 4 100% 0

Classes with closest relation at Level 1


Rank Class id link
1 36640 CAS 56583 43 8//CAS 17692 39 6//2 HYDROXYPROPL BETA CYCLODEXTRIN
2 34050 2 OXO 3 HYDROXY LSD//LYSERGIC ACID DIETHYLAMIDE//LYSERGIC ACID DIETHYLAMIDE LSD
3 36569 ANTIBIOTIC ASSOCIATED HEMORRHAGIC COLITIS//NONPSEUDOMEMBRANOUS COLITIS//ANTIBIOTIC ASSOCIATED AND HAEMORRHAGIC COLITIS
4 5760 INTESTINAL SECRETION//SORBIN//E COLI STA
5 5525 JOURNAL OF TRAVEL MEDICINE//TRAVELERS DIARRHEA//TRAVEL MEDICINE
6 9862 P GLYCOPROTEIN//PHARMACORESISTANCE//TARIQUIDAR
7 22780 CHEMILUMINESCENCE RESONANCE ENERGY TRANSFER//ENGN CLEAN PROD DYEING PRINTING//POST CHEMILUMINESCENCE REACTION
8 8810 PERIPHERAL OPIOID RECEPTORS//PERIPHERAL OPIOID ANALGESIA//KLIN ANAESTHESIOL OPERAT INTENS MED
9 34514 LATHYRINE//LATHYRUS TINGITANUS//2 AMINO 4 CARBOXYPYRIMIDINE
10 16225 REPAGLINIDE//NATEGLINIDE//MITIGLINIDE

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