Class information for:
Level 2: ALZHEIMERS DISEASE//AMYLOID PRECURSOR PROTEIN//TAU

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
35 32531 52.2 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
49 3       ALZHEIMERS DISEASE//AMYOTROPHIC LATERAL SCLEROSIS//DEMENTIA 92146
35 2             ALZHEIMERS DISEASE//AMYLOID PRECURSOR PROTEIN//TAU 32531
361 1                   TAU//TAUOPATHY//PAIRED HELICAL FILAMENTS 3588
478 1                   AMYLOID BETA PEPTIDE//AMYLOID BETA PROTEIN//ALZHEIMERS DISEASE 3390
1390 1                   PRESENILIN//GAMMA SECRETASE//PRESENILIN 1 2684
1430 1                   AMYLOID PRECURSOR PROTEIN//BETA AMYLOID PRECURSOR PROTEIN//ALZHEIMERS DISEASE 2670
1446 1                   APOLIPOPROTEIN E//APOE//APOLIPOPROTEIN E4 2660
3379 1                   ALZHEIMERS DISEASE//BAPINEUZUMAB//AMYLOID BETA 1997
4001 1                   MEMBRANE SCI//SANDERS BROWN AGING//ALZHEIMERS DISEASE 1865
4073 1                   CEREBRAL AMYLOID ANGIOPATHY//CEREBRAL MICROBLEEDS//MICROBLEEDS 1852
5058 1                   CEREBROSPINAL FLUID//PSYCHIAT NEUROCHEM//CLIN MEMORY UNIT 1680
6474 1                   24S HYDROXYCHOLESTEROL//CYP46//CYP46A1 1479
9059 1                   BACE1//BETA SECRETASE//BACE1 INHIBITOR 1191
9210 1                   FE65//AMYLOID PRECURSOR PROTEIN//APP 1177
10591 1                   STUDY NEURODEGENERAT DIS//BURKE MED//MITOCHONDRIA 1050
11336 1                   SORL1//TOMM40//PICALM 990
14129 1                   NEUROFIBRILLARY TANGLES//SENILE PLAQUES//BETA A4 DEPOSITS 790
18624 1                   APP RATIO//CONFORMATIONALLY ALTERED P53//GERIATR MEDKFC 544
19190 1                   CALHM1//CALCIUM HOMEOSTASIS MODULATOR 1//MOL NEUROPATHOGENESIS 517
20963 1                   GLUTAMINYL CYCLASE//INTRANEURONAL A BETA//PYROGLUTAMATE 439
21946 1                   APOPTOSIS AND CEREBROVASCULAR INJURY//APOPTOSIS AND NEURODEGENERATION//BRAIN AGING DEMENTIA 399
22032 1                   ALPHA 1 ANTICHYMOTRYPSIN//ALPHA1 ANTICHYMOTRYPSIN POLYMORPHISM//SERUM ALPHA1 ANTICHYMOTRYPSIN 396
22367 1                   CELLULAR NEUROSCI NEURODEGENERAT REPAIR PROGRAM//AMYLOID BETA PEPTIDE 25 35//AMYLOID BETA PROTEIN OLIGOMERS 384
24950 1                   MEMORY AND LEARNING IMPAIRMENT//GAMMA SECRETASE ACTIVATING PROTEIN//ALZHEIMER KOR KUTATOCSOPORT 296
28746 1                   HUMANIN//COLIVELIN//S14G HUMANIN 200
31869 1                   FAMILIAL BRITISH DEMENTIA//FAMILIAL DANISH DEMENTIA//BRI2 147
31950 1                   CLINICAL DEMENTIA//MENTAL IMPAIRMENTS NEUROL DISORDERS MIND//PHARMACONEUROIMMUNOL PROGRAM 146

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 ALZHEIMERS DISEASE authKW 3007325 36% 28% 11714
2 AMYLOID PRECURSOR PROTEIN authKW 621973 3% 64% 1032
3 TAU authKW 607655 4% 44% 1462
4 AMYLOID BETA authKW 541227 4% 44% 1312
5 PRESENILIN authKW 454722 2% 75% 649
6 BETA AMYLOID authKW 440024 3% 42% 1114
7 APOLIPOPROTEIN E authKW 413329 4% 37% 1213
8 AMYLOID authKW 397544 5% 29% 1469
9 AMYLOID BETA PEPTIDE authKW 367897 2% 54% 731
10 JOURNAL OF ALZHEIMERS DISEASE journal 321371 4% 28% 1247

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Neurosciences 200103 46% 2% 14903
2 Clinical Neurology 52323 19% 1% 6027
3 Geriatrics & Gerontology 42867 6% 2% 2085
4 Biochemistry & Molecular Biology 27988 27% 1% 8879
5 Pathology 9697 6% 1% 1800
6 Biophysics 4628 5% 0% 1760
7 Cell Biology 4250 8% 0% 2565
8 Chemistry, Medicinal 2021 3% 0% 1015
9 Psychiatry 1901 4% 0% 1268
10 Medicine, Research & Experimental 908 3% 0% 1045

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 NEUROL 113966 17% 2% 5648
2 ALZHEIMERS DIS 84852 1% 23% 402
3 NEUROL DIS 73228 1% 22% 358
4 GENET AGING UNIT 62601 0% 57% 118
5 NEURODEGENERAT DIS 62275 1% 14% 473
6 SANDERS BROWN AGING 57017 1% 22% 285
7 NEUROSCI 56880 8% 3% 2580
8 ALZHEIMERS PARKINSONS DIS 53744 0% 64% 90
9 NEUROPATHOL NEUROSCI 53083 0% 49% 117
10 MEMBRANE SCI 42514 0% 36% 127

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 JOURNAL OF ALZHEIMERS DISEASE 321371 4% 28% 1247
2 NEUROBIOLOGY OF AGING 186500 3% 19% 1073
3 CURRENT ALZHEIMER RESEARCH 70278 1% 28% 267
4 MOLECULAR NEURODEGENERATION 48276 1% 30% 170
5 NEURODEGENERATIVE DISEASES 39554 1% 25% 171
6 ACTA NEUROPATHOLOGICA 33050 1% 8% 458
7 JOURNAL OF NEUROCHEMISTRY 29162 3% 4% 822
8 ALZHEIMERS RESEARCH & THERAPY 28166 0% 29% 103
9 NEUROBIOLOGY OF DISEASE 27525 1% 9% 331
10 ALZHEIMERS REPORTS 24911 0% 44% 60

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 ALZHEIMERS DISEASE 3007325 36% 28% 11714 Search ALZHEIMERS+DISEASE Search ALZHEIMERS+DISEASE
2 AMYLOID PRECURSOR PROTEIN 621973 3% 64% 1032 Search AMYLOID+PRECURSOR+PROTEIN Search AMYLOID+PRECURSOR+PROTEIN
3 TAU 607655 4% 44% 1462 Search TAU Search TAU
4 AMYLOID BETA 541227 4% 44% 1312 Search AMYLOID+BETA Search AMYLOID+BETA
5 PRESENILIN 454722 2% 75% 649 Search PRESENILIN Search PRESENILIN
6 BETA AMYLOID 440024 3% 42% 1114 Search BETA+AMYLOID Search BETA+AMYLOID
7 APOLIPOPROTEIN E 413329 4% 37% 1213 Search APOLIPOPROTEIN+E Search APOLIPOPROTEIN+E
8 AMYLOID 397544 5% 29% 1469 Search AMYLOID Search AMYLOID
9 AMYLOID BETA PEPTIDE 367897 2% 54% 731 Search AMYLOID+BETA+PEPTIDE Search AMYLOID+BETA+PEPTIDE
10 CEREBRAL AMYLOID ANGIOPATHY 312219 1% 75% 447 Search CEREBRAL+AMYLOID+ANGIOPATHY Search CEREBRAL+AMYLOID+ANGIOPATHY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 HAMLEY, IW , (2012) THE AMYLOID BETA PEPTIDE: A CHEMIST'S PERSPECTIVE. ROLE IN ALZHEIMER'S AND FIBRILLIZATION.CHEMICAL REVIEWS. VOL. 112. ISSUE 10. P. 5147 -5192 532 75% 181
2 NASICA-LABOUZE, J , NGUYEN, PH , STERPONE, F , BERTHOUMIEU, O , BUCHETE, NV , COTE, S , DE SIMONE, A , DOIG, AJ , FALLER, P , GARCIA, A , ET AL (2015) AMYLOID BETA PROTEIN AND ALZHEIMER'S DISEASE: WHEN COMPUTER SIMULATIONS COMPLEMENT EXPERIMENTAL STUDIES.CHEMICAL REVIEWS. VOL. 115. ISSUE 9. P. 3518 -3563 377 75% 51
3 SELKOE, DJ , (2001) ALZHEIMER'S DISEASE: GENES, PROTEINS, AND THERAPY.PHYSIOLOGICAL REVIEWS. VOL. 81. ISSUE 2. P. 741 -766 186 91% 3524
4 MATTSON, MP , (1997) CELLULAR ACTIONS OF BETA-AMYLOID PRECURSOR PROTEIN AND ITS SOLUBLE AND FIBRILLOGENIC DERIVATIVES.PHYSIOLOGICAL REVIEWS. VOL. 77. ISSUE 4. P. 1081-1132 412 75% 648
5 ARENDT, T , STIELER, JT , HOLZER, M , (2016) TAU AND TAUOPATHIES.BRAIN RESEARCH BULLETIN. VOL. 126. ISSUE . P. 238 -292 567 57% 0
6 DILLEN, K , ANNAERT, W , (2006) A TWO DECADE CONTRIBUTION OF MOLECULAR CELL BIOLOGY TO THE CENTENNIAL OF ALZHEIMER'S DISEASE: ARE WE PROGRESSING TOWARD THERAPY?.INTERNATIONAL REVIEW OF CYTOLOGY - A SURVEY OF CELL BIOLOGY, VOL 254. VOL. 254. ISSUE . P. 215-300 426 84% 19
7 ESKICI, G , AXELSEN, PH , (2012) COPPER AND OXIDATIVE STRESS IN THE PATHOGENESIS OF ALZHEIMER'S DISEASE.BIOCHEMISTRY. VOL. 51. ISSUE 32. P. 6289 -6311 314 75% 77
8 SUH, YH , CHECLER, F , (2002) AMYLOID PRECURSOR PROTEIN, PRESENILINS, AND ALPHA-SYNUCLEIN: MOLECULAR PATHOGENESIS AND PHARMACOLOGICAL APPLICATIONS IN ALZHEIMER'S DISEASE.PHARMACOLOGICAL REVIEWS. VOL. 54. ISSUE 3. P. 469 -525 451 62% 299
9 KIM, J , BASAK, JM , HOLTZMAN, DM , (2009) THE ROLE OF APOLIPOPROTEIN E IN ALZHEIMER'S DISEASE.NEURON. VOL. 63. ISSUE 3. P. 287-303 191 83% 469
10 DE STROOPER, B , (2010) PROTEASES AND PROTEOLYSIS IN ALZHEIMER DISEASE: A MULTIFACTORIAL VIEW ON THE DISEASE PROCESS.PHYSIOLOGICAL REVIEWS. VOL. 90. ISSUE 2. P. 465-494 265 75% 167

Classes with closest relation at Level 2


Rank Class id link
1 823 DIFFUSION TENSOR IMAGING//TRACTOGRAPHY//ALZHEIMERS DISEASE
2 2319 SENESCENCE ACCELERATED MOUSE//SAMP8//SENESCENCE ACCELERATED MOUSE SAM
3 2464 STREPTOZOTOCIN//KANGEN KARYU//HYPERCYTOLIPIDEMIA
4 967 AMYLOIDOSIS//TRANSTHYRETIN//AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
5 259 DEMENTIA//MILD COGNITIVE IMPAIRMENT//ALZHEIMERS DISEASE
6 3815 CLUSTERIN//APOLIPOPROTEIN J//SULFATED GLYCOPROTEIN 2
7 3099 ALPHA 2 MACROGLOBULIN//LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN//LRP1
8 903 MICROGLIA//BRAIN BEHAVIOR AND IMMUNITY//CYTOKINES
9 2731 DOWN SYNDROME//DYRK1A//TS65DN
10 1440 ACETYLCHOLINESTERASE//BUTYRYLCHOLINESTERASE//TACRINE

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