Class information for:
Level 1: FE65//AMYLOID PRECURSOR PROTEIN//APP

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9210 1177 54.0 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
49 3       ALZHEIMERS DISEASE//AMYOTROPHIC LATERAL SCLEROSIS//DEMENTIA 92146
35 2             ALZHEIMERS DISEASE//AMYLOID PRECURSOR PROTEIN//TAU 32531
9210 1                   FE65//AMYLOID PRECURSOR PROTEIN//APP 1177

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FE65 authKW 1442139 6% 86% 65
2 AMYLOID PRECURSOR PROTEIN authKW 819403 19% 14% 225
3 APP authKW 329420 9% 12% 103
4 ALCADEIN authKW 233476 1% 100% 9
5 X11 authKW 224206 1% 79% 11
6 APP INTRACELLULAR DOMAIN authKW 216178 1% 83% 10
7 AICD authKW 210781 3% 25% 32
8 APLP1 authKW 199548 1% 77% 10
9 AMYLOID PRECURSOR LIKE PROTEIN authKW 185293 1% 71% 10
10 AMYLOID PRECURSOR LIKE PROTEIN 2 authKW 162363 1% 48% 13

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 8521 49% 0% 582
2 Biochemistry & Molecular Biology 2732 41% 0% 486
3 Cell Biology 1648 20% 0% 241
4 Geriatrics & Gerontology 212 3% 0% 30
5 Biophysics 184 6% 0% 66
6 Developmental Biology 80 2% 0% 24
7 Clinical Neurology 68 5% 0% 58
8 Biology 19 2% 0% 22
9 Genetics & Heredity 17 3% 0% 37
10 Cell & Tissue Engineering 9 0% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN BIOL HUMAN GENET 89669 1% 31% 11
2 CELL SIGNALING NEURODEGENERAT CSIN 77825 0% 100% 3
3 ZACHARY ELIZABETH M FISHER 77825 0% 100% 3
4 TRANSDUCAO SINAIS 69167 1% 33% 8
5 BONNER FORUM BIOMED 57054 1% 20% 11
6 PROT CRYSTALLOG GRP 47151 1% 18% 10
7 DIPARTIMENTO FARMACOL NEUROSCI 46693 0% 60% 3
8 DIPARTIMENTO BIOCHIM BIOTECNOL MED 39185 2% 6% 27
9 PHARM MOL BIOTECHNOL 38782 3% 4% 35
10 BIOINFORMAT FUNCT GEN 37728 0% 36% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEURODEGENERATIVE DISEASES 10864 1% 2% 17
2 JOURNAL OF ALZHEIMERS DISEASE 8678 3% 1% 39
3 MOLECULAR NEURODEGENERATION 6671 1% 2% 12
4 JOURNAL OF NEUROCHEMISTRY 4564 5% 0% 61
5 FRONTIERS IN MOLECULAR NEUROSCIENCE 4438 1% 2% 10
6 JOURNAL OF NEUROSCIENCE 4237 6% 0% 75
7 CURRENT ALZHEIMER RESEARCH 2725 1% 1% 10
8 JOURNAL OF BIOLOGICAL CHEMISTRY 2668 11% 0% 128
9 NEUROBIOLOGY OF AGING 1955 2% 0% 21
10 NEUROBIOLOGY OF DISEASE 1788 1% 0% 16

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FE65 1442139 6% 86% 65 Search FE65 Search FE65
2 AMYLOID PRECURSOR PROTEIN 819403 19% 14% 225 Search AMYLOID+PRECURSOR+PROTEIN Search AMYLOID+PRECURSOR+PROTEIN
3 APP 329420 9% 12% 103 Search APP Search APP
4 ALCADEIN 233476 1% 100% 9 Search ALCADEIN Search ALCADEIN
5 X11 224206 1% 79% 11 Search X11 Search X11
6 APP INTRACELLULAR DOMAIN 216178 1% 83% 10 Search APP+INTRACELLULAR+DOMAIN Search APP+INTRACELLULAR+DOMAIN
7 AICD 210781 3% 25% 32 Search AICD Search AICD
8 APLP1 199548 1% 77% 10 Search APLP1 Search APLP1
9 AMYLOID PRECURSOR LIKE PROTEIN 185293 1% 71% 10 Search AMYLOID+PRECURSOR+LIKE+PROTEIN Search AMYLOID+PRECURSOR+LIKE+PROTEIN
10 AMYLOID PRECURSOR LIKE PROTEIN 2 162363 1% 48% 13 Search AMYLOID+PRECURSOR+LIKE+PROTEIN+2 Search AMYLOID+PRECURSOR+LIKE+PROTEIN+2

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MULLER, UC , ZHENG, H , (2012) PHYSIOLOGICAL FUNCTIONS OF APP FAMILY PROTEINS.COLD SPRING HARBOR PERSPECTIVES IN MEDICINE. VOL. 2. ISSUE 2. P. - 119 71% 67
2 MULLER, T , MEYER, HE , EGENSPERGER, R , MARCUS, K , (2008) THE AMYLOID PRECURSOR PROTEIN INTRACELLULAR DOMAIN (AICD) AS MODULATOR OF GENE EXPRESSION, APOPTOSIS, AND CYTOSKELETAL DYNAMICS - RELEVANCE FOR ALZHEIMER'S DISEASE.PROGRESS IN NEUROBIOLOGY. VOL. 85. ISSUE 4. P. 393 -406 104 71% 131
3 ZHENG, H , KOO, EH , (2011) BIOLOGY AND PATHOPHYSIOLOGY OF THE AMYLOID PRECURSOR PROTEIN.MOLECULAR NEURODEGENERATION. VOL. 6. ISSUE . P. - 114 56% 89
4 DEYTS, C , THINAKARAN, G , PARENT, AT , (2016) APP RECEPTOR? TO BE OR NOT TO BE.TRENDS IN PHARMACOLOGICAL SCIENCES. VOL. 37. ISSUE 5. P. 390 -411 114 48% 5
5 TARU, H , SUZUKI, T , (2009) REGULATION OF THE PHYSIOLOGICAL FUNCTION AND METABOLISM OF A BETA PP BY A BETA PP BINDING PROTEINS.JOURNAL OF ALZHEIMERS DISEASE. VOL. 18. ISSUE 2. P. 253 -265 92 79% 7
6 CHOW, WNV , CHEUNG, HNM , LI, W , LAU, KF , (2015) FE65: ROLES BEYOND AMYLOID PRECURSOR PROTEIN PROCESSING.CELLULAR & MOLECULAR BIOLOGY LETTERS. VOL. 20. ISSUE 1. P. 66 -87 64 86% 2
7 MCLOUGHLIN, DM , MILLER, CCJ , (2008) THE FE65 PROTEINS AND ALZHEIMER'S DISEASE.JOURNAL OF NEUROSCIENCE RESEARCH. VOL. 86. ISSUE 4. P. 744 -754 70 80% 74
8 AYDIN, D , WEYER, SW , MULLER, UC , (2012) FUNCTIONS OF THE APP GENE FAMILY IN THE NERVOUS SYSTEM: INSIGHTS FROM MOUSE MODELS.EXPERIMENTAL BRAIN RESEARCH. VOL. 217. ISSUE 3-4. P. 423-434 62 82% 37
9 JACOBSEN, KT , IVERFELDT, K , (2009) AMYLOID PRECURSOR PROTEIN AND ITS HOMOLOGUES: A FAMILY OF PROTEOLYSIS-DEPENDENT RECEPTORS.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 66. ISSUE 14. P. 2299 -2318 94 55% 65
10 LUDEWIG, S , KORTE, M , (2017) NOVEL INSIGHTS INTO THE PHYSIOLOGICAL FUNCTION OF THE APP (GENE) FAMILY AND ITS PROTEOLYTIC FRAGMENTS IN SYNAPTIC PLASTICITY.FRONTIERS IN MOLECULAR NEUROSCIENCE. VOL. 9. ISSUE . P. - 76 64% 0

Classes with closest relation at Level 1


Rank Class id link
1 1430 AMYLOID PRECURSOR PROTEIN//BETA AMYLOID PRECURSOR PROTEIN//ALZHEIMERS DISEASE
2 1390 PRESENILIN//GAMMA SECRETASE//PRESENILIN 1
3 9059 BACE1//BETA SECRETASE//BACE1 INHIBITOR
4 31869 FAMILIAL BRITISH DEMENTIA//FAMILIAL DANISH DEMENTIA//BRI2
5 28746 HUMANIN//COLIVELIN//S14G HUMANIN
6 22367 CELLULAR NEUROSCI NEURODEGENERAT REPAIR PROGRAM//AMYLOID BETA PEPTIDE 25 35//AMYLOID BETA PROTEIN OLIGOMERS
7 20963 GLUTAMINYL CYCLASE//INTRANEURONAL A BETA//PYROGLUTAMATE
8 35314 UBIQUILIN//UBIQUILIN 1//UBQLN1
9 27709 NATIONAL ALZHEIMERS COORDINATING CENTER NACC//BRAIN INJURY DEMENTIA//PUBL POLICY ADVOCACY
10 19190 CALHM1//CALCIUM HOMEOSTASIS MODULATOR 1//MOL NEUROPATHOGENESIS

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