Class information for:
Level 1: AMYLOID BETA PEPTIDE//AMYLOID BETA PROTEIN//ALZHEIMERS DISEASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
478 3390 55.2 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
49 3       ALZHEIMERS DISEASE//AMYOTROPHIC LATERAL SCLEROSIS//DEMENTIA 92146
35 2             ALZHEIMERS DISEASE//AMYLOID PRECURSOR PROTEIN//TAU 32531
478 1                   AMYLOID BETA PEPTIDE//AMYLOID BETA PROTEIN//ALZHEIMERS DISEASE 3390

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMYLOID BETA PEPTIDE authKW 251830 6% 14% 195
2 AMYLOID BETA PROTEIN authKW 224470 4% 17% 147
3 ALZHEIMERS DISEASE authKW 198717 29% 2% 973
4 AMYLOID authKW 186301 10% 6% 324
5 PROTOFIBRILS authKW 184958 1% 45% 46
6 OLIGOMERS authKW 159001 6% 9% 201
7 AMYLOID BETA authKW 143650 6% 7% 218
8 AMYLOID FIBRILS authKW 121189 3% 13% 102
9 FIBRILS authKW 85755 2% 12% 80
10 BETA SHEET BREAKER authKW 80094 0% 68% 13

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 12039 50% 0% 1687
2 Biophysics 6154 16% 0% 548
3 Neurosciences 2355 17% 0% 589
4 Chemistry, Medicinal 1697 7% 0% 248
5 Chemistry, Physical 652 12% 0% 416
6 Chemistry, Multidisciplinary 590 11% 0% 388
7 Physics, Atomic, Molecular & Chemical 179 4% 0% 143
8 Biochemical Research Methods 177 3% 0% 115
9 Geriatrics & Gerontology 137 1% 0% 46
10 Cell Biology 117 5% 0% 176

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHIM THEOR 59839 1% 15% 44
2 NEUROL NEUROBIOL AGING 49227 1% 17% 33
3 STRUCT BIOCHEM ICS 6 35033 0% 32% 12
4 UPR 9080 34702 1% 15% 25
5 NEUROL DIS 30169 2% 5% 74
6 SECT DRUG DEPENDENCE 28816 0% 80% 4
7 TAN CHANH HIEP WARD 28808 0% 40% 8
8 ICMG FR 27017 0% 100% 3
9 PPSN EA4674 27017 0% 100% 3
10 STUDIES MOL IMAGING 27017 0% 100% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ACS CHEMICAL NEUROSCIENCE 61619 2% 9% 79
2 AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS 7715 1% 3% 26
3 JOURNAL OF ALZHEIMERS DISEASE 7315 2% 1% 61
4 BIOPHYSICAL JOURNAL 6818 4% 1% 123
5 JOURNAL OF MOLECULAR BIOLOGY 4596 3% 0% 111
6 BIOCHEMISTRY 4535 5% 0% 168
7 JOURNAL OF PEPTIDE SCIENCE 3874 1% 2% 28
8 JOURNAL OF PHYSICAL CHEMISTRY B 3774 4% 0% 130
9 CURRENT ALZHEIMER RESEARCH 3403 1% 2% 19
10 CHEMBIOCHEM 2147 1% 1% 33

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AMYLOID BETA PEPTIDE 251830 6% 14% 195 Search AMYLOID+BETA+PEPTIDE Search AMYLOID+BETA+PEPTIDE
2 AMYLOID BETA PROTEIN 224470 4% 17% 147 Search AMYLOID+BETA+PROTEIN Search AMYLOID+BETA+PROTEIN
3 ALZHEIMERS DISEASE 198717 29% 2% 973 Search ALZHEIMERS+DISEASE Search ALZHEIMERS+DISEASE
4 AMYLOID 186301 10% 6% 324 Search AMYLOID Search AMYLOID
5 PROTOFIBRILS 184958 1% 45% 46 Search PROTOFIBRILS Search PROTOFIBRILS
6 OLIGOMERS 159001 6% 9% 201 Search OLIGOMERS Search OLIGOMERS
7 AMYLOID BETA 143650 6% 7% 218 Search AMYLOID+BETA Search AMYLOID+BETA
8 AMYLOID FIBRILS 121189 3% 13% 102 Search AMYLOID+FIBRILS Search AMYLOID+FIBRILS
9 FIBRILS 85755 2% 12% 80 Search FIBRILS Search FIBRILS
10 BETA SHEET BREAKER 80094 0% 68% 13 Search BETA+SHEET+BREAKER Search BETA+SHEET+BREAKER

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 NASICA-LABOUZE, J , NGUYEN, PH , STERPONE, F , BERTHOUMIEU, O , BUCHETE, NV , COTE, S , DE SIMONE, A , DOIG, AJ , FALLER, P , GARCIA, A , ET AL (2015) AMYLOID BETA PROTEIN AND ALZHEIMER'S DISEASE: WHEN COMPUTER SIMULATIONS COMPLEMENT EXPERIMENTAL STUDIES.CHEMICAL REVIEWS. VOL. 115. ISSUE 9. P. 3518 -3563 290 58% 51
2 HAMLEY, IW , (2012) THE AMYLOID BETA PEPTIDE: A CHEMIST'S PERSPECTIVE. ROLE IN ALZHEIMER'S AND FIBRILLIZATION.CHEMICAL REVIEWS. VOL. 112. ISSUE 10. P. 5147 -5192 270 38% 181
3 SHEA, JE , URBANC, B , (2012) INSIGHTS INTO A BETA AGGREGATION: A MOLECULAR DYNAMICS PERSPECTIVE.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 12. ISSUE 22. P. 2596-2610 136 86% 25
4 NAGEL-STEGER, L , OWEN, MC , STRODEL, B , (2016) AN ACCOUNT OF AMYLOID OLIGOMERS: FACTS AND FIGURES OBTAINED FROM EXPERIMENTS AND SIMULATIONS.CHEMBIOCHEM. VOL. 17. ISSUE 8. P. 657 -676 115 54% 8
5 HUBIN, E , VAN NULAND, NAJ , BROERSEN, K , PAUWELS, K , (2014) TRANSIENT DYNAMICS OF A BETA CONTRIBUTE TO TOXICITY IN ALZHEIMER'S DISEASE.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 71. ISSUE 18. P. 3507 -3521 110 60% 28
6 DASILVA, KA , SHAW, JE , MCLAURIN, J , (2010) AMYLOID-BETA FIBRILLOGENESIS: STRUCTURAL INSIGHT AND THERAPEUTIC INTERVENTION.EXPERIMENTAL NEUROLOGY. VOL. 223. ISSUE 2. P. 311-321 98 77% 61
7 MASTERS, CL , SELKOE, DJ , (2012) BIOCHEMISTRY OF AMYLOID BETA-PROTEIN AND AMYLOID DEPOSITS IN ALZHEIMER DISEASE.COLD SPRING HARBOR PERSPECTIVES IN MEDICINE. VOL. 2. ISSUE 6. P. - 109 50% 142
8 JANG, H , ARCE, FT , RAMACHANDRAN, S , KAGAN, BL , LAL, R , NUSSINOV, R , (2014) DISORDERED AMYLOIDOGENIC PEPTIDES MAY INSERT INTO THE MEMBRANE AND ASSEMBLE INTO COMMON CYCLIC STRUCTURAL MOTIFS.CHEMICAL SOCIETY REVIEWS. VOL. 43. ISSUE 19. P. 6750 -6764 110 64% 12
9 MOHAMED, A , CORTEZ, L , DE CHAVES, EP , (2011) AGGREGATION STATE AND NEUROTOXIC PROPERTIES OF ALZHEIMER BETA-AMYLOID PEPTIDE.CURRENT PROTEIN & PEPTIDE SCIENCE. VOL. 12. ISSUE 3. P. 235-257 162 48% 13
10 RAHIMI, F , SHANMUGAM, A , BITAN, G , (2008) STRUCTURE-FUNCTION RELATIONSHIPS OF PRE-FIBRILLAR PROTEIN ASSEMBLIES IN ALZHEIMER'S DISEASE AND RELATED DISORDERS.CURRENT ALZHEIMER RESEARCH. VOL. 5. ISSUE 3. P. 319 -341 138 56% 52

Classes with closest relation at Level 1


Rank Class id link
1 2153 AMYLOID FIBRILS//AMYLOID//DIALYSIS RELATED AMYLOIDOSIS
2 22367 CELLULAR NEUROSCI NEURODEGENERAT REPAIR PROGRAM//AMYLOID BETA PEPTIDE 25 35//AMYLOID BETA PROTEIN OLIGOMERS
3 20963 GLUTAMINYL CYCLASE//INTRANEURONAL A BETA//PYROGLUTAMATE
4 30760 ACIDIC OLIGOSACCHARIDE SUGAR CHAIN//HEPARIN DERIVED OLIGOSACCHARIDE//NEUROPATHOL S
5 4001 MEMBRANE SCI//SANDERS BROWN AGING//ALZHEIMERS DISEASE
6 3379 ALZHEIMERS DISEASE//BAPINEUZUMAB//AMYLOID BETA
7 37210 SEVI//ULM PEPTIDE PHARMACEUT//BIOMOL SCI BURNETT BIOMED SCI
8 5248 AMYLIN//ISLET AMYLOID POLYPEPTIDE//IAPP
9 31869 FAMILIAL BRITISH DEMENTIA//FAMILIAL DANISH DEMENTIA//BRI2
10 14501 BETA AMYLOID PLAQUES//CHRYSAMINE G//WUHAN NEUROSCI NEUROENGN

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