Class information for:
Level 1: CALHM1//CALCIUM HOMEOSTASIS MODULATOR 1//MOL NEUROPATHOGENESIS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
19190 517 59.2 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
49 3       ALZHEIMERS DISEASE//AMYOTROPHIC LATERAL SCLEROSIS//DEMENTIA 92146
35 2             ALZHEIMERS DISEASE//AMYLOID PRECURSOR PROTEIN//TAU 32531
19190 1                   CALHM1//CALCIUM HOMEOSTASIS MODULATOR 1//MOL NEUROPATHOGENESIS 517

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CALHM1 authKW 551231 3% 67% 14
2 CALCIUM HOMEOSTASIS MODULATOR 1 authKW 413430 1% 100% 7
3 MOL NEUROPATHOGENESIS address 177178 1% 50% 6
4 REGULATION OF NEUROTRANSMITTER RELEASE authKW 118123 0% 100% 2
5 LITWIN ZUCKER STUDY ALZHEIMERS DIS address 111241 2% 21% 9
6 PRESENILIN authKW 93188 7% 4% 37
7 CORTICAL SYNAPTOSOMES authKW 78747 0% 67% 2
8 MOL NEURODEGENERAT address 72678 2% 15% 8
9 TRANSLAT BRAIN address 70304 1% 24% 5
10 3 X TG AD authKW 59061 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 4819 56% 0% 288
2 Geriatrics & Gerontology 3876 15% 0% 77
3 Cell Biology 651 20% 0% 101
4 Biochemistry & Molecular Biology 211 21% 0% 106
5 Physiology 102 6% 0% 30
6 Medicine, Research & Experimental 55 5% 0% 26
7 Pharmacology & Pharmacy 30 7% 0% 37
8 Clinical Neurology 25 5% 0% 24
9 Biophysics 12 3% 0% 15
10 CYTOLOGY & HISTOLOGY 6 0% 0% 1

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL NEUROPATHOGENESIS 177178 1% 50% 6
2 LITWIN ZUCKER STUDY ALZHEIMERS DIS 111241 2% 21% 9
3 MOL NEURODEGENERAT 72678 2% 15% 8
4 TRANSLAT BRAIN 70304 1% 24% 5
5 DEUT ZENTRUM NEURODEGENERAT ERKRANKUNGEN EV MU 59061 0% 100% 1
6 EDUC CHINA NEUROL DISORDERS 59061 0% 100% 1
7 GERIATR UNIT GERONTOL GERIATR 59061 0% 100% 1
8 GRP THOMAS OERTNER 59061 0% 100% 1
9 HRH PRINCE ALWALEED BIN TALAL BIN ABDULAZIX ALSAU 59061 0% 100% 1
10 KAROLINSKA SUMITOMO PHARMACEUT ALZHEIMER 59061 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROBIOLOGY OF AGING 11161 6% 1% 33
2 CELL CALCIUM 5272 3% 1% 16
3 AGING CELL 4805 2% 1% 10
4 JOURNAL OF ALZHEIMERS DISEASE 3753 3% 0% 17
5 MOLECULAR NEURODEGENERATION 2636 1% 1% 5
6 MECHANISMS OF AGEING AND DEVELOPMENT 2109 2% 0% 12
7 CHINESE LAW AND GOVERNMENT 1255 0% 2% 1
8 JOURNAL OF NEUROSCIENCE 1149 5% 0% 26
9 SCIENCE SIGNALING 948 1% 0% 5
10 JOURNAL OF NEUROCHEMISTRY 893 3% 0% 18

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CALHM1 551231 3% 67% 14 Search CALHM1 Search CALHM1
2 CALCIUM HOMEOSTASIS MODULATOR 1 413430 1% 100% 7 Search CALCIUM+HOMEOSTASIS+MODULATOR+1 Search CALCIUM+HOMEOSTASIS+MODULATOR+1
3 REGULATION OF NEUROTRANSMITTER RELEASE 118123 0% 100% 2 Search REGULATION+OF+NEUROTRANSMITTER+RELEASE Search REGULATION+OF+NEUROTRANSMITTER+RELEASE
4 PRESENILIN 93188 7% 4% 37 Search PRESENILIN Search PRESENILIN
5 CORTICAL SYNAPTOSOMES 78747 0% 67% 2 Search CORTICAL+SYNAPTOSOMES Search CORTICAL+SYNAPTOSOMES
6 3 X TG AD 59061 0% 100% 1 Search 3+X+TG+AD Search 3+X+TG+AD
7 A BETA 42 MONOMERS 59061 0% 100% 1 Search A+BETA+42+MONOMERS Search A+BETA+42+MONOMERS
8 A BETA 42 OLIGOMERS 59061 0% 100% 1 Search A+BETA+42+OLIGOMERS Search A+BETA+42+OLIGOMERS
9 A BETA42 OLIGOMERS 59061 0% 100% 1 Search A+BETA42+OLIGOMERS Search A+BETA42+OLIGOMERS
10 ACUTE DISSOCIATION OF NEURONS 59061 0% 100% 1 Search ACUTE+DISSOCIATION+OF+NEURONS Search ACUTE+DISSOCIATION+OF+NEURONS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 POPUGAEVA, E , BEZPROZVANNY, I , (2013) ROLE OF ENDOPLASMIC RETICULUM CA2+ SIGNALING IN THE PATHOGENESIS OF ALZHEIMER DISEASE.FRONTIERS IN MOLECULAR NEUROSCIENCE. VOL. 6. ISSUE . P. - 40 60% 17
2 LIANG, JY , KULASIRI, D , SAMARASINGHE, S , (2015) CA2+ DYSREGULATION IN THE ENDOPLASMIC RETICULUM RELATED TO ALZHEIMER'S DISEASE: A REVIEW ON EXPERIMENTAL PROGRESS AND COMPUTATIONAL MODELING.BIOSYSTEMS. VOL. 134. ISSUE . P. 1 -15 58 34% 4
3 THIBAULT, O , PANCANI, T , LANDFIELD, PW , NORRIS, CM , (2012) REDUCTION IN NEURONAL L-TYPE CALCIUM CHANNEL ACTIVITY IN A DOUBLE KNOCK-IN MOUSE MODEL OF ALZHEIMER'S DISEASE.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. VOL. 1822. ISSUE 4. P. 546-549 26 65% 9
4 SUPNET, C , BEZPROZVANNY, I , (2010) THE DYSREGULATION OF INTRACELLULAR CALCIUM IN ALZHEIMER DISEASE.CELL CALCIUM. VOL. 47. ISSUE 2. P. 183 -189 34 39% 101
5 YU, JT , CHANG, RCC , TAN, L , (2009) CALCIUM DYSREGULATION IN ALZHEIMER'S DISEASE: FROM MECHANISMS TO THERAPEUTIC OPPORTUNITIES.PROGRESS IN NEUROBIOLOGY. VOL. 89. ISSUE 3. P. 240-255 55 27% 69
6 SHILLING, D , MAK, DOD , KANG, DE , FOSKETT, JK , (2012) LACK OF EVIDENCE FOR PRESENILINS AS ENDOPLASMIC RETICULUM CA2+ LEAK CHANNELS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 287. ISSUE 14. P. 10933-10944 24 57% 35
7 LOPEZ, JR , LYCKMAN, A , ODDO, S , LAFERLA, FM , QUERFURTH, HW , SHTIFMAN, A , (2008) INCREASED INTRANEURONAL RESTING [CA2+] IN ADULT ALZHEIMER'S DISEASE MICE.JOURNAL OF NEUROCHEMISTRY. VOL. 105. ISSUE 1. P. 262-271 29 52% 70
8 CHEUNG, KH , SHINEMAN, D , MULLER, M , CARDENAS, C , MEI, LJ , YANG, J , TOMITA, T , IWATSUBO, T , LEE, VMY , FOSKETT, JK , (2008) MECHANISM OF CA2+ DISRUPTION IN ALZHEIMER'S DISEASE BY PRESENILIN REGULATION OF INSP(3) RECEPTOR CHANNEL GATING.NEURON. VOL. 58. ISSUE 6. P. 871-883 28 43% 212
9 DEL PRETE, D , CHECLER, F , CHAMI, M , (2014) RYANODINE RECEPTORS: PHYSIOLOGICAL FUNCTION AND DEREGULATION IN ALZHEIMER DISEASE.MOLECULAR NEURODEGENERATION. VOL. 9. ISSUE . P. - 45 27% 14
10 AGOSTINI, M , FASOLATO, C , (2016) WHEN, WHERE AND HOW? FOCUS ON NEURONAL CALCIUM DYSFUNCTIONS IN ALZHEIMER'S DISEASE.CELL CALCIUM. VOL. 60. ISSUE 5. P. 289 -298 40 32% 0

Classes with closest relation at Level 1


Rank Class id link
1 22367 CELLULAR NEUROSCI NEURODEGENERAT REPAIR PROGRAM//AMYLOID BETA PEPTIDE 25 35//AMYLOID BETA PROTEIN OLIGOMERS
2 18624 APP RATIO//CONFORMATIONALLY ALTERED P53//GERIATR MEDKFC
3 1390 PRESENILIN//GAMMA SECRETASE//PRESENILIN 1
4 7957 NEUROBIOLOGY OF AGING//AGING//GERIATRICS & GERONTOLOGY
5 12462 SK CHANNELS//APAMIN//AFTERHYPERPOLARIZATION
6 15879 EXCITOTOXICITY//RETINAL CELLS//CL DEPENDENT EXCITOTOXICITY
7 27975 MOL CELLULAR SIGNALING//TAT BH4//2 EPI 2 O ACETYLTHEVETIN BGHSC 74
8 31950 CLINICAL DEMENTIA//MENTAL IMPAIRMENTS NEUROL DISORDERS MIND//PHARMACONEUROIMMUNOL PROGRAM
9 10591 STUDY NEURODEGENERAT DIS//BURKE MED//MITOCHONDRIA
10 15452 HISTOL EMBRYOL NEUROCYTOL//KASTOR NEUROBIOL AGING S//NEUROBIOLOGY OF AGING

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