Class information for:
Level 1: 24S HYDROXYCHOLESTEROL//CYP46//CYP46A1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6474 1479 56.4 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
49 3       ALZHEIMERS DISEASE//AMYOTROPHIC LATERAL SCLEROSIS//DEMENTIA 92146
35 2             ALZHEIMERS DISEASE//AMYLOID PRECURSOR PROTEIN//TAU 32531
6474 1                   24S HYDROXYCHOLESTEROL//CYP46//CYP46A1 1479

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 24S HYDROXYCHOLESTEROL authKW 1248832 5% 86% 70
2 CYP46 authKW 460804 2% 89% 25
3 CYP46A1 authKW 422884 2% 79% 26
4 OXYSTEROLS authKW 341103 8% 14% 117
5 27 HYDROXYCHOLESTEROL authKW 304360 3% 36% 41
6 CHOLESTEROL 24S HYDROXYLASE authKW 289020 1% 100% 14
7 BRAIN CHOLESTEROL authKW 276010 1% 70% 19
8 CHOLESTEROL 24 HYDROXYLASE authKW 269750 1% 93% 14
9 24 HYDROXYCHOLESTEROL authKW 264240 1% 80% 16
10 CHOLESTEROL authKW 225075 29% 3% 427

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 7651 42% 0% 625
2 Geriatrics & Gerontology 4001 9% 0% 134
3 Clinical Neurology 1958 17% 0% 251
4 Biochemistry & Molecular Biology 1122 26% 0% 384
5 Psychiatry 302 6% 0% 92
6 Gerontology 286 2% 0% 29
7 Pharmacology & Pharmacy 237 10% 0% 147
8 Cell Biology 146 7% 0% 106
9 Biophysics 83 4% 0% 57
10 Nutrition & Dietetics 68 2% 0% 36

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ROBERTS NEURODEGENERAT DIS 167217 1% 90% 9
2 BIO NIEDERURSEL 69347 1% 20% 17
3 AGING NEUROBIOL PROGRAMME 64510 0% 63% 5
4 BEREZOV 61933 0% 100% 3
5 CLIN PATHOL MED GENET 55727 1% 30% 9
6 EXPT CLIN BIOMED SCI DSBSC 41289 0% 100% 2
7 RALPH MURIEL ROBERTS NEURODEGENERAT 41289 0% 100% 2
8 ZAFES BIO NIEDERURSEL 41289 0% 100% 2
9 METAB FITNESS 39107 0% 32% 6
10 LEGEL UW AGEING 37157 0% 60% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF ALZHEIMERS DISEASE 19225 4% 1% 65
2 CURRENT ALZHEIMER RESEARCH 5561 1% 2% 16
3 DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 4824 1% 1% 21
4 NEUROBIOLOGY OF AGING 4599 2% 1% 36
5 JOURNAL OF LIPID RESEARCH 4423 3% 1% 43
6 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 2746 1% 1% 19
7 MOLECULAR NEUROBIOLOGY 2673 1% 1% 17
8 NEURODEGENERATIVE DISEASES 2413 1% 1% 9
9 JOURNAL OF NEUROCHEMISTRY 2029 3% 0% 46
10 NEUROSCIENCE LETTERS 1522 3% 0% 49

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 24S HYDROXYCHOLESTEROL 1248832 5% 86% 70 Search 24S+HYDROXYCHOLESTEROL Search 24S+HYDROXYCHOLESTEROL
2 CYP46 460804 2% 89% 25 Search CYP46 Search CYP46
3 CYP46A1 422884 2% 79% 26 Search CYP46A1 Search CYP46A1
4 OXYSTEROLS 341103 8% 14% 117 Search OXYSTEROLS Search OXYSTEROLS
5 27 HYDROXYCHOLESTEROL 304360 3% 36% 41 Search 27+HYDROXYCHOLESTEROL Search 27+HYDROXYCHOLESTEROL
6 CHOLESTEROL 24S HYDROXYLASE 289020 1% 100% 14 Search CHOLESTEROL+24S+HYDROXYLASE Search CHOLESTEROL+24S+HYDROXYLASE
7 BRAIN CHOLESTEROL 276010 1% 70% 19 Search BRAIN+CHOLESTEROL Search BRAIN+CHOLESTEROL
8 CHOLESTEROL 24 HYDROXYLASE 269750 1% 93% 14 Search CHOLESTEROL+24+HYDROXYLASE Search CHOLESTEROL+24+HYDROXYLASE
9 24 HYDROXYCHOLESTEROL 264240 1% 80% 16 Search 24+HYDROXYCHOLESTEROL Search 24+HYDROXYCHOLESTEROL
10 CHOLESTEROL 225075 29% 3% 427 Search CHOLESTEROL Search CHOLESTEROL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MOUTINHO, M , NUNES, MJ , RODRIGUES, E , (2016) CHOLESTEROL 24-HYDROXYLASE: BRAIN CHOLESTEROL METABOLISM AND BEYOND.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1861. ISSUE 12. P. 1911 -1920 107 84% 0
2 SOLOMON, A , KIVIPELTO, M , (2009) CHOLESTEROL-MODIFYING STRATEGIES FOR ALZHEIMER'S DISEASE.EXPERT REVIEW OF NEUROTHERAPEUTICS. VOL. 9. ISSUE 5. P. 695-709 80 77% 21
3 STEPHENSON, NE , CROWE, SF , (2016) STATIN USE, AGEING, AND COGNITION: A REVIEW.AUSTRALIAN PSYCHOLOGIST. VOL. 51. ISSUE 3. P. 188 -205 71 74% 0
4 RICHARDSON, K , SCHOEN, M , FRENCH, B , UMSCHEID, CA , MITCHELL, MD , ARNOLD, SE , HEIDENREICH, PA , RADER, DJ , DEGOMA, EM , (2013) STATINS AND COGNITIVE FUNCTION.ANNALS OF INTERNAL MEDICINE. VOL. 159. ISSUE 10. P. 688 -+ 53 74% 78
5 LEONI, V , CACCIA, C , (2013) 24S-HYDROXYCHOLESTEROL IN PLASMA: A MARKER OF CHOLESTEROL TURNOVER IN NEURODEGENERATIVE DISEASES.BIOCHIMIE. VOL. 95. ISSUE 3. P. 595 -612 91 52% 26
6 FONSECA, ACRG , RESENDE, R , OLIVEIRA, CR , PEREIRA, CMF , (2010) CHOLESTEROL AND STATINS IN ALZHEIMER'S DISEASE: CURRENT CONTROVERSIES.EXPERIMENTAL NEUROLOGY. VOL. 223. ISSUE 2. P. 282-293 102 50% 43
7 MENDOZA-OLIVA, A , ZEPEDA, A , ARIAS, C , (2014) THE COMPLEX ACTIONS OF STATINS IN BRAIN AND THEIR RELEVANCE FOR ALZHEIMER'S DISEASE TREATMENT: AN ANALYTICAL REVIEW.CURRENT ALZHEIMER RESEARCH. VOL. 11. ISSUE 9. P. 817 -833 96 52% 3
8 SWIGER, KJ , MANALAC, RJ , BLUMENTHAL, RS , MD, MJB , MARTIN, SS , (2013) STATINS AND COGNITION: A SYSTEMATIC REVIEW AND META-ANALYSIS OF SHORT- AND LONG-TERM COGNITIVE EFFECTS.MAYO CLINIC PROCEEDINGS. VOL. 88. ISSUE 11. P. 1213-1221 43 90% 58
9 SCHREURS, BG , (2010) THE EFFECTS OF CHOLESTEROL ON LEARNING AND MEMORY.NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. VOL. 34. ISSUE 8. P. 1366 -1379 101 48% 32
10 LEONI, V , CACCIA, C , (2015) THE IMPAIRMENT OF CHOLESTEROL METABOLISM IN HUNTINGTON DISEASE.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1851. ISSUE 8. P. 1095 -1105 66 59% 12

Classes with closest relation at Level 1


Rank Class id link
1 19923 HLTH FAMILY STUDIES//CHOLESTEROL//ALICIA KOPLOWITZ FDN FELLOWSHIP
2 1446 APOLIPOPROTEIN E//APOE//APOLIPOPROTEIN E4
3 7709 VASCULAR RISK FACTORS//BRAIN HYPOPERFUSION//HOP BROCA
4 10090 LIVER X RECEPTOR//LXR//T0901317
5 15692 STATINS//GRP COGNIT DECLINE DEGENERAT VASC DISORDERS//GRP PHARMACOL CEREBRAL I EMIA
6 36199 CC MM//HLTH ENVIRONM CYSMA//CAMPUS EXCELLENCE INT CEIA3
7 9039 CEREBROTENDINOUS XANTHOMATOSIS//CHOLESTEROL 7 ALPHA HYDROXYLASE//STEROL 27 HYDROXYLASE
8 5179 OXYSTEROLS//CHOLESTEROL OXIDES//CHOLESTEROL OXIDATION PRODUCTS
9 6069 NIEMANN PICK DISEASE TYPE C//NIEMANN PICK TYPE C//NIEMANN PICK DISEASE
10 10482 SMITH LEMLI OPITZ SYNDROME//7 DEHYDROCHOLESTEROL//CHONDRODYSPLASIA PUNCTATA

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