Class information for:
Level 1: APOLIPOPROTEIN E//APOE//APOLIPOPROTEIN E4

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1446 2660 49.1 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
49 3       ALZHEIMERS DISEASE//AMYOTROPHIC LATERAL SCLEROSIS//DEMENTIA 92146
35 2             ALZHEIMERS DISEASE//AMYLOID PRECURSOR PROTEIN//TAU 32531
1446 1                   APOLIPOPROTEIN E//APOE//APOLIPOPROTEIN E4 2660

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 APOLIPOPROTEIN E authKW 2686461 33% 27% 882
2 APOE authKW 735062 11% 22% 295
3 APOLIPOPROTEIN E4 authKW 245271 2% 46% 46
4 ALZHEIMERS DISEASE authKW 191638 32% 2% 846
5 APOLIPOPROTEIN E APOE authKW 109595 1% 29% 33
6 APOE4 authKW 96719 1% 30% 28
7 APOE EPSILON 4 ALLELE authKW 77558 1% 48% 14
8 APOLIPOPROTEIN E GENOTYPE authKW 75955 1% 28% 24
9 APOE GENOTYPE authKW 75290 1% 21% 32
10 491 A T POLYMORPHISM authKW 70299 0% 88% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Neurosciences 20322 51% 0% 1349
2 Clinical Neurology 12489 30% 0% 809
3 Geriatrics & Gerontology 7382 9% 0% 244
4 Psychiatry 1806 10% 0% 275
5 Gerontology 883 3% 0% 67
6 Pathology 461 4% 0% 117
7 Biochemistry & Molecular Biology 414 15% 0% 393
8 Neuroimaging 319 2% 0% 40
9 Psychology 169 2% 0% 59
10 Genetics & Heredity 163 5% 0% 126

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOSEPH KATHLEEN BRYAN ALZHEIMERS DIS 42477 1% 19% 20
2 GLADSTONE NEUROL DIS 35406 1% 11% 27
3 BRYAN ALZHEIMERS DIS 32046 0% 31% 9
4 MULTIDISCIPLINARY NEUROPROTECT 30604 0% 67% 4
5 HOPE NEUROL DISORDERS NEUROL 26231 0% 57% 4
6 SIR JAMES MCCUSKER ALZHEIMERS UNIT 25823 0% 75% 3
7 STUDY NERVOUS SYST INJURY 24515 1% 11% 20
8 ANAL CLIN DR ECHEVARNE 22955 0% 100% 2
9 BIOCHEM GEN METAB 22955 0% 100% 2
10 BRYAN ARDC 22955 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ALZHEIMERS REPORTS 19103 1% 11% 15
2 NEUROBIOLOGY OF AGING 13310 3% 1% 82
3 JOURNAL OF ALZHEIMERS DISEASE 12698 3% 2% 71
4 DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 12335 2% 2% 45
5 NEUROLOGY 7523 4% 1% 119
6 MOLECULAR NEURODEGENERATION 6630 1% 3% 18
7 NEUROSCIENCE LETTERS 6173 5% 0% 131
8 AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS 3340 1% 2% 14
9 ALZHEIMERS & DEMENTIA 3030 1% 2% 15
10 ALZHEIMER DISEASE & ASSOCIATED DISORDERS 2922 1% 1% 19

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 APOLIPOPROTEIN E 2686461 33% 27% 882 Search APOLIPOPROTEIN+E Search APOLIPOPROTEIN+E
2 APOE 735062 11% 22% 295 Search APOE Search APOE
3 APOLIPOPROTEIN E4 245271 2% 46% 46 Search APOLIPOPROTEIN+E4 Search APOLIPOPROTEIN+E4
4 ALZHEIMERS DISEASE 191638 32% 2% 846 Search ALZHEIMERS+DISEASE Search ALZHEIMERS+DISEASE
5 APOLIPOPROTEIN E APOE 109595 1% 29% 33 Search APOLIPOPROTEIN+E+APOE Search APOLIPOPROTEIN+E+APOE
6 APOE4 96719 1% 30% 28 Search APOE4 Search APOE4
7 APOE EPSILON 4 ALLELE 77558 1% 48% 14 Search APOE+EPSILON+4+ALLELE Search APOE+EPSILON+4+ALLELE
8 APOLIPOPROTEIN E GENOTYPE 75955 1% 28% 24 Search APOLIPOPROTEIN+E+GENOTYPE Search APOLIPOPROTEIN+E+GENOTYPE
9 APOE GENOTYPE 75290 1% 21% 32 Search APOE+GENOTYPE Search APOE+GENOTYPE
10 491 A T POLYMORPHISM 70299 0% 88% 7 Search 491+A+T+POLYMORPHISM Search 491+A+T+POLYMORPHISM

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KIM, J , BASAK, JM , HOLTZMAN, DM , (2009) THE ROLE OF APOLIPOPROTEIN E IN ALZHEIMER'S DISEASE.NEURON. VOL. 63. ISSUE 3. P. 287-303 156 68% 469
2 LIU, CC , KANEKIYO, T , XU, HX , BU, GJ , (2013) APOLIPOPROTEIN E AND ALZHEIMER DISEASE: RISK, MECHANISMS AND THERAPY.NATURE REVIEWS NEUROLOGY. VOL. 9. ISSUE 2. P. 106-118 94 57% 314
3 HUANG, YD , MAHLEY, RW , (2014) APOLIPOPROTEIN E: STRUCTURE AND FUNCTION IN LIPID METABOLISM, NEUROBIOLOGY, AND ALZHEIMER'S DISEASES.NEUROBIOLOGY OF DISEASE. VOL. 72. ISSUE . P. 3 -12 101 72% 43
4 MAHLEY, RW , WEISGRABER, KH , HUANG, YD , (2006) APOLIPOPROTEIN E4: A CAUSATIVE FACTOR AND THERAPEUTIC TARGET IN NEUROPATHOLOGY INCLUDING ALZHEIMER'S DISEASE.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. VOL. 103. ISSUE 15. P. 5644-5651 99 64% 464
5 VERGHESE, PB , CASTELLANO, JM , HOLTZMAN, DM , (2011) APOLIPOPROTEIN E IN ALZHEIMER'S DISEASE AND OTHER NEUROLOGICAL DISORDERS.LANCET NEUROLOGY. VOL. 10. ISSUE 3. P. 241-252 92 56% 252
6 HUANG, YD , (2010) A BETA-INDEPENDENT ROLES OF APOLIPOPROTEIN E4 IN THE PATHOGENESIS OF ALZHEIMER'S DISEASE.TRENDS IN MOLECULAR MEDICINE. VOL. 16. ISSUE 6. P. 287-294 97 80% 47
7 DIBATTISTA, AM , HEINSINGER, NM , REBECK, GW , (2016) ALZHEIMER'S DISEASE GENETIC RISK FACTOR APOE-EPSILON 4 ALSO AFFECTS NORMAL BRAIN FUNCTION.CURRENT ALZHEIMER RESEARCH. VOL. 13. ISSUE 11. P. 1200 -1207 89 77% 1
8 TETER, B , (2000) APOLIPOPROTEIN E ISOTYPE-SPECIFIC EFFECTS IN NEURODEGENERATION.ALZHEIMERS REPORTS. VOL. 3. ISSUE 4. P. 199 -212 149 72% 6
9 HUANG, YD , (2006) APOLIPOPROTEIN E AND ALZHEIMER DISEASE.NEUROLOGY. VOL. 66. ISSUE . P. S79-S85 98 80% 67
10 DE CHAVES, EP , NARAYANASWAMI, V , (2008) APOLIPOPROTEIN E AND CHOLESTEROL IN AGING AND DISEASE IN THE BRAIN.FUTURE LIPIDOLOGY. VOL. 3. ISSUE 5. P. 505-530 153 50% 34

Classes with closest relation at Level 1


Rank Class id link
1 22032 ALPHA 1 ANTICHYMOTRYPSIN//ALPHA1 ANTICHYMOTRYPSIN POLYMORPHISM//SERUM ALPHA1 ANTICHYMOTRYPSIN
2 3171 APOLIPOPROTEIN E//LIPOPROTEIN GLOMERULOPATHY//TYPE III HYPERLIPOPROTEINEMIA
3 27709 NATIONAL ALZHEIMERS COORDINATING CENTER NACC//BRAIN INJURY DEMENTIA//PUBL POLICY ADVOCACY
4 11336 SORL1//TOMM40//PICALM
5 6474 24S HYDROXYCHOLESTEROL//CYP46//CYP46A1
6 17503 ANGULAR HOMEOSTASIS//RELATIVE INFORMANTS//FAMILIAL ALZHEIMER
7 12747 SECT ENDOCRINOL DIABET METAB MC 797//APOLIPOPROTEIN E//FAMILIAL DYSLIPOPROTEINEMIA
8 26436 APOLIPOPROTEIN D//APOLIPOPROTEIN D APOD//APOD
9 734 MILD COGNITIVE IMPAIRMENT//ALZHEIMERS DISEASE//AMYLOID IMAGING
10 26906 INT ALZHEIMER//HERPES SIMPLEX TYPE 1 VIRUS//HERPES SIMPLEX VIRUS TYPE 1 HSV1

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