Class information for:
Level 1: AMYLOID PRECURSOR PROTEIN//BETA AMYLOID PRECURSOR PROTEIN//ALZHEIMERS DISEASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1430 2670 46.4 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
49 3       ALZHEIMERS DISEASE//AMYOTROPHIC LATERAL SCLEROSIS//DEMENTIA 92146
35 2             ALZHEIMERS DISEASE//AMYLOID PRECURSOR PROTEIN//TAU 32531
1430 1                   AMYLOID PRECURSOR PROTEIN//BETA AMYLOID PRECURSOR PROTEIN//ALZHEIMERS DISEASE 2670

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMYLOID PRECURSOR PROTEIN authKW 612288 11% 18% 293
2 BETA AMYLOID PRECURSOR PROTEIN authKW 483703 4% 36% 116
3 ALZHEIMERS DISEASE authKW 232390 35% 2% 933
4 BETA AMYLOID authKW 166408 7% 7% 196
5 AMYLOID BETA PROTEIN authKW 111594 3% 11% 92
6 SENILE PLAQUES authKW 109216 3% 13% 76
7 BETA A4 authKW 82320 0% 60% 12
8 AMYLOID BETA A4 PROTEIN PRECURSOR authKW 80042 0% 100% 7
9 BETA PROTEIN authKW 77551 1% 32% 21
10 A4CT authKW 68608 0% 100% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Neurosciences 26529 57% 0% 1533
2 Geriatrics & Gerontology 3910 7% 0% 180
3 Biochemistry & Molecular Biology 3539 33% 0% 869
4 Pathology 3359 11% 0% 282
5 Clinical Neurology 2114 14% 0% 361
6 Biophysics 990 8% 0% 213
7 Cell Biology 212 7% 0% 178
8 Medicine, Research & Experimental 167 4% 0% 111
9 Genetics & Heredity 32 3% 0% 80
10 Medicine, General & Internal 18 3% 0% 82

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FISHER ALZHEIMER 30490 0% 67% 4
2 PSYCHIAT MOL NEUROGENET 25982 0% 45% 5
3 MED BIOCHEM ALZHEIMERS DIS GRP 22869 0% 100% 2
4 NEUROBIOL AGING GERONTOL 22869 0% 100% 2
5 ST MARYS HOSP MED BIOCHEM 22869 0% 100% 2
6 CREAT INITIAT ALZHEIMERS DEMENTIA 21512 0% 24% 8
7 PSYCHIATMRC 223 20580 0% 60% 3
8 NS KLINE 14698 0% 43% 3
9 TRANSDUCAO SINAIS 11903 0% 21% 5
10 AFFILIATED YANTAI YUHUANGDING HOSP QINGDAO 11435 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROBIOLOGY OF AGING 32451 5% 2% 128
2 MOLECULAR BRAIN RESEARCH 14168 3% 2% 75
3 AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS 11381 1% 4% 28
4 ALZHEIMERS REPORTS 10229 0% 8% 11
5 NEURODEGENERATION 9897 0% 7% 12
6 ACTA NEUROPATHOLOGICA 9802 3% 1% 71
7 NEUROSCIENCE LETTERS 8105 6% 0% 150
8 AMYLOID-INTERNATIONAL JOURNAL OF EXPERIMENTAL AND CLINICAL INVESTIGATION 7616 0% 17% 4
9 JOURNAL OF NEUROCHEMISTRY 6143 4% 1% 107
10 MOLECULAR AND CHEMICAL NEUROPATHOLOGY 5545 1% 3% 16

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AMYLOID PRECURSOR PROTEIN 612288 11% 18% 293 Search AMYLOID+PRECURSOR+PROTEIN Search AMYLOID+PRECURSOR+PROTEIN
2 BETA AMYLOID PRECURSOR PROTEIN 483703 4% 36% 116 Search BETA+AMYLOID+PRECURSOR+PROTEIN Search BETA+AMYLOID+PRECURSOR+PROTEIN
3 ALZHEIMERS DISEASE 232390 35% 2% 933 Search ALZHEIMERS+DISEASE Search ALZHEIMERS+DISEASE
4 BETA AMYLOID 166408 7% 7% 196 Search BETA+AMYLOID Search BETA+AMYLOID
5 AMYLOID BETA PROTEIN 111594 3% 11% 92 Search AMYLOID+BETA+PROTEIN Search AMYLOID+BETA+PROTEIN
6 SENILE PLAQUES 109216 3% 13% 76 Search SENILE+PLAQUES Search SENILE+PLAQUES
7 BETA A4 82320 0% 60% 12 Search BETA+A4 Search BETA+A4
8 AMYLOID BETA A4 PROTEIN PRECURSOR 80042 0% 100% 7 Search AMYLOID+BETA+A4+PROTEIN+PRECURSOR Search AMYLOID+BETA+A4+PROTEIN+PRECURSOR
9 BETA PROTEIN 77551 1% 32% 21 Search BETA+PROTEIN Search BETA+PROTEIN
10 A4CT 68608 0% 100% 6 Search A4CT Search A4CT

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MATTSON, MP , (1997) CELLULAR ACTIONS OF BETA-AMYLOID PRECURSOR PROTEIN AND ITS SOLUBLE AND FIBRILLOGENIC DERIVATIVES.PHYSIOLOGICAL REVIEWS. VOL. 77. ISSUE 4. P. 1081-1132 256 47% 648
2 PANEGYRES, PK , (2001) THE FUNCTIONS OF THE AMYLOID PRECURSOR PROTEIN GENE.REVIEWS IN THE NEUROSCIENCES. VOL. 12. ISSUE 1. P. 1 -39 281 61% 27
3 LEBLANC, A , (1994) THE ROLE OF BETA-AMYLOID PEPTIDE IN ALZHEIMERS-DISEASE.METABOLIC BRAIN DISEASE. VOL. 9. ISSUE 1. P. 3-31 169 85% 4
4 SELKOE, DJ , (1994) NORMAL AND ABNORMAL BIOLOGY OF THE BETA-AMYLOID PRECURSOR PROTEIN.ANNUAL REVIEW OF NEUROSCIENCE. VOL. 17. ISSUE . P. 489-517 89 78% 711
5 GREENBERG, BD , SAVAGE, MJ , HOWLAND, DS , ALI, SM , SIEDLAK, SL , PERRY, G , SIMAN, R , SCOTT, RW , (1996) APP TRANSGENESIS: APPROACHES TOWARD THE DEVELOPMENT OF ANIMAL MODELS FOR ALZHEIMER DISEASE NEUROPATHOLOGY.NEUROBIOLOGY OF AGING. VOL. 17. ISSUE 2. P. 153 -171 184 63% 30
6 CHECLER, F , (1995) PROCESSING OF THE BETA-AMYLOID PRECURSOR PROTEIN AND ITS REGULATION IN ALZHEIMERS-DISEASE.JOURNAL OF NEUROCHEMISTRY. VOL. 65. ISSUE 4. P. 1431 -1444 96 88% 321
7 MILLS, J , REINER, PB , (1999) REGULATION OF AMYLOID PRECURSOR PROTEIN CLEAVAGE.JOURNAL OF NEUROCHEMISTRY. VOL. 72. ISSUE 2. P. 443 -460 131 57% 180
8 COUGHLAN, CM , BREEN, KC , (2000) FACTORS INFLUENCING THE PROCESSING AND FUNCTION OF THE AMYLOID BETA PRECURSOR PROTEIN - A POTENTIAL THERAPEUTIC TARGET IN ALZHEIMER'S DISEASE?.PHARMACOLOGY & THERAPEUTICS. VOL. 86. ISSUE 2. P. 111 -144 203 42% 36
9 SUH, YH , (1997) AN ETIOLOGICAL ROLE OF AMYLOIDOGENIC CARBOXYL-TERMINAL FRAGMENTS OF THE BETA-AMYLOID PRECURSOR PROTEIN IN ALZHEIMER'S DISEASE.JOURNAL OF NEUROCHEMISTRY. VOL. 68. ISSUE 5. P. 1781 -1791 102 87% 40
10 PANEGYRES, PK , (1997) THE AMYLOID PRECURSOR PROTEIN GENE: A NEUROPEPTIDE GENE WITH DIVERSE FUNCTIONS IN THE CENTRAL NERVOUS SYSTEM.NEUROPEPTIDES. VOL. 31. ISSUE 6. P. 523 -535 124 73% 16

Classes with closest relation at Level 1


Rank Class id link
1 9210 FE65//AMYLOID PRECURSOR PROTEIN//APP
2 30760 ACIDIC OLIGOSACCHARIDE SUGAR CHAIN//HEPARIN DERIVED OLIGOSACCHARIDE//NEUROPATHOL S
3 18624 APP RATIO//CONFORMATIONALLY ALTERED P53//GERIATR MEDKFC
4 14129 NEUROFIBRILLARY TANGLES//SENILE PLAQUES//BETA A4 DEPOSITS
5 22032 ALPHA 1 ANTICHYMOTRYPSIN//ALPHA1 ANTICHYMOTRYPSIN POLYMORPHISM//SERUM ALPHA1 ANTICHYMOTRYPSIN
6 20963 GLUTAMINYL CYCLASE//INTRANEURONAL A BETA//PYROGLUTAMATE
7 17503 ANGULAR HOMEOSTASIS//RELATIVE INFORMANTS//FAMILIAL ALZHEIMER
8 22367 CELLULAR NEUROSCI NEURODEGENERAT REPAIR PROGRAM//AMYLOID BETA PEPTIDE 25 35//AMYLOID BETA PROTEIN OLIGOMERS
9 1390 PRESENILIN//GAMMA SECRETASE//PRESENILIN 1
10 34202 I EM NEURODEGENERAT BRAIN//NEONATE INFANT PATHOL//POSTISCHEMIC DEMENTIA

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