Class information for:
Level 2: GENE THERAPY//ADENOVIRUS//HUMAN GENE THERAPY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
564 14456 45.6 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
419 3       ADENOVIRUS//MERKEL CELL CARCINOMA//GENE THERAPY 28518
564 2             GENE THERAPY//ADENOVIRUS//HUMAN GENE THERAPY 14456
1181 1                   ONCOLYTIC VIRUS//ONCOLYTIC ADENOVIRUS//VIROTHERAPY 2800
1257 1                   ADENO ASSOCIATED VIRUS//AAV//POWELL GENE THER Y 2758
3599 1                   ADENOVIRUS//COXSACKIE ADENOVIRUS RECEPTOR//HUMAN GENE THER Y 1947
3940 1                   SUICIDE GENE THERAPY//CYTOSINE DEAMINASE//HERPES SIMPLEX VIRUS THYMIDINE KINASE 1877
6997 1                   MOL MED GENE THER Y UNIT//ADENOVIRUS//HELPER DEPENDENT ADENOVIRAL VECTOR 1418
9238 1                   RESTENOSIS//GENE THERAPY//LOCAL DRUG DELIVERY 1175
16206 1                   GENE MED GRP//GENEMED GRP//EXPT TREATMENT CYST FIBROSIS 667
16216 1                   IN UTERO TRANSPLANTATION//FETAL GENE THERAPY//CHILDRENS SURG SCI 666
16830 1                   RAD P53//RECOMBINANT ADENOVIRUS P53//ADENOVIRAL MEDIATED INTERFERON ALPHA 633
27919 1                   GENE THER Y SCI//RECOMBINANT SENDAI VIRUS//HVJ E 218
28833 1                   GENETIC RADIOTHERAPY//TNFERADE//CARG ELEMENTS 198
35297 1                   S GAL//3 D REGISTRATION AND RECONSTRUCTION//3 GALACTOSIDASE 99

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 GENE THERAPY authKW 889189 17% 17% 2465
2 ADENOVIRUS authKW 839051 10% 28% 1418
3 HUMAN GENE THERAPY journal 592987 7% 29% 968
4 ONCOLYTIC VIRUS authKW 494544 2% 70% 333
5 GENE THER Y address 435809 5% 28% 745
6 ADENO ASSOCIATED VIRUS authKW 411515 3% 41% 479
7 MOLECULAR THERAPY journal 371245 5% 22% 790
8 CANCER GENE THERAPY journal 349728 4% 29% 570
9 HUMAN GENE THER Y address 321335 2% 47% 321
10 ONCOLYTIC ADENOVIRUS authKW 293510 1% 75% 185

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Medicine, Research & Experimental 117028 34% 1% 4886
2 Biotechnology & Applied Microbiology 78999 32% 1% 4591
3 Genetics & Heredity 69751 29% 1% 4250
4 Virology 40457 13% 1% 1891
5 Oncology 19018 20% 0% 2927
6 Biochemistry & Molecular Biology 3260 17% 0% 2409
7 Hematology 1312 4% 0% 539
8 Cell Biology 930 6% 0% 901
9 Peripheral Vascular Diseases 567 3% 0% 379
10 Cardiac & Cardiovascular System 461 4% 0% 519

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENE THER Y 435809 5% 28% 745
2 HUMAN GENE THER Y 321335 2% 47% 321
3 CANC GENE THER Y GRP 156088 1% 70% 105
4 GENE THER Y PROGRAM 116244 1% 32% 172
5 POWELL GENE THER Y 98694 1% 38% 123
6 SAN DIEGO SCI 69551 0% 63% 52
7 CELLULAR MOL THER Y 59423 0% 46% 61
8 GENE TRANSFER REGULAT 53721 0% 58% 44
9 MOL MED GENE THER Y UNIT 44067 0% 67% 31
10 XINYUAN MED BIOTECHNOL 41501 0% 41% 48

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN GENE THERAPY 592987 7% 29% 968
2 GENE THERAPY 527254 7% 25% 989
3 MOLECULAR THERAPY 371245 5% 22% 790
4 CANCER GENE THERAPY 349728 4% 29% 570
5 JOURNAL OF GENE MEDICINE 114886 2% 20% 277
6 HUMAN GENE THERAPY METHODS 53633 0% 39% 65
7 CURRENT GENE THERAPY 46421 1% 20% 110
8 JOURNAL OF VIROLOGY 45841 6% 2% 939
9 MOLECULAR THERAPY-ONCOLYTICS 30116 0% 48% 30
10 CURRENT OPINION IN MOLECULAR THERAPEUTICS 23997 1% 11% 100

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 GENE THERAPY 889189 17% 17% 2465 Search GENE+THERAPY Search GENE+THERAPY
2 ADENOVIRUS 839051 10% 28% 1418 Search ADENOVIRUS Search ADENOVIRUS
3 ONCOLYTIC VIRUS 494544 2% 70% 333 Search ONCOLYTIC+VIRUS Search ONCOLYTIC+VIRUS
4 ADENO ASSOCIATED VIRUS 411515 3% 41% 479 Search ADENO+ASSOCIATED+VIRUS Search ADENO+ASSOCIATED+VIRUS
5 ONCOLYTIC ADENOVIRUS 293510 1% 75% 185 Search ONCOLYTIC+ADENOVIRUS Search ONCOLYTIC+ADENOVIRUS
6 VIROTHERAPY 228758 1% 66% 164 Search VIROTHERAPY Search VIROTHERAPY
7 AAV 217550 2% 44% 233 Search AAV Search AAV
8 SUICIDE GENE THERAPY 161755 1% 61% 126 Search SUICIDE+GENE+THERAPY Search SUICIDE+GENE+THERAPY
9 ADENOVIRUS VECTOR 161003 1% 38% 202 Search ADENOVIRUS+VECTOR Search ADENOVIRUS+VECTOR
10 CYTOSINE DEAMINASE 157191 1% 59% 126 Search CYTOSINE+DEAMINASE Search CYTOSINE+DEAMINASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 COUGHLAN, L , ALBA, R , PARKER, AL , BRADSHAW, AC , MCNEISH, IA , NICKLIN, SA , BAKER, AH , (2010) TROPISM-MODIFICATION STRATEGIES FOR TARGETED GENE DELIVERY USING ADENOVIRAL VECTORS.VIRUSES-BASEL. VOL. 2. ISSUE 10. P. 2290 -2355 314 85% 34
2 MITCHELL, AM , NICOLSON, SC , WARISCHALK, JK , SAMULSKI, RJ , (2010) AAV'S ANATOMY: ROADMAP FOR OPTIMIZING VECTORS FOR TRANSLATIONAL SUCCESS.CURRENT GENE THERAPY. VOL. 10. ISSUE 5. P. 319 -340 199 75% 38
3 MATHIS, JM , STOFF-KHALILI, MA , CURIEL, DT , (2005) ONCOLYTIC ADENOVIRUSES - SELECTIVE RETARGETING TO TUMOR CELLS.ONCOGENE. VOL. 24. ISSUE 52. P. 7775-7791 201 84% 75
4 RUSSELL, SJ , PENG, KW , BELL, JC , (2012) ONCOLYTIC VIROTHERAPY.NATURE BIOTECHNOLOGY. VOL. 30. ISSUE 7. P. 658 -670 110 70% 331
5 AHI, YS , BANGARI, DS , MITTAL, SK , (2011) ADENOVIRAL VECTOR IMMUNITY: ITS IMPLICATIONS AND CIRCUMVENTION STRATEGIES.CURRENT GENE THERAPY. VOL. 11. ISSUE 4. P. 307-320 178 81% 31
6 SAMULSKI, RJ , MUZYCZKA, N , (2014) AAV-MEDIATED GENE THERAPY FOR RESEARCH AND THERAPEUTIC PURPOSES.ANNUAL REVIEW OF VIROLOGY, VOL 1. VOL. 1. ISSUE . P. 427 -451 156 78% 27
7 BUNING, H , PERABO, L , COUTELLE, O , QUADT-HUMME, S , HALLEK, M , (2008) RECENT DEVELOPMENTS IN ADENO-ASSOCIATED VIRUS VECTOR TECHNOLOGY.JOURNAL OF GENE MEDICINE. VOL. 10. ISSUE 7. P. 717-733 154 91% 77
8 PESONEN, S , KANGASNIEMI, L , HEMININKI, A , (2011) ONCOLYTIC ADENOVIRUSES FOR THE TREATMENT OF HUMAN CANCER: FOCUS ON TRANSLATIONAL AND CLINICAL DATA.MOLECULAR PHARMACEUTICS. VOL. 8. ISSUE 1. P. 12 -28 163 80% 50
9 ZHANG, LM , TATSUYA, T , NISHIYAMA, Y , (2016) ONCOTARGET STRATEGIES FOR HERPES SIMPLEX VIRUS-1.CURRENT GENE THERAPY. VOL. 16. ISSUE 2. P. 130 -143 175 78% 0
10 BALAKRISHNAN, B , JAYANDHARAN, GR , (2014) BASIC BIOLOGY OF ADENO-ASSOCIATED VIRUS (AAV) VECTORS USED IN GENE THERAPY.CURRENT GENE THERAPY. VOL. 14. ISSUE 2. P. 86 -100 152 86% 9

Classes with closest relation at Level 2


Rank Class id link
1 2151 ADENOVIRUS//E1A//EPIDEMIC KERATOCONJUNCTIVITIS
2 476 GENE DELIVERY//CELL PENETRATING PEPTIDE//CATIONIC LIPID
3 636 ENDOGENOUS RETROVIRUS//RETROVIRUS//RETROVIRAL VECTOR
4 140 IMMUNOTHERAPY//DENDRITIC CELLS//CANCER IMMUNOLOGY IMMUNOTHERAPY
5 3470 CONVECTION ENHANCED DELIVERY//POLYANHYDRIDE//POLYESTER ANHYDRIDE
6 1115 GENOME EDITING//CRISPR CAS9//CRISPR
7 545 VIROLOGY//JOURNAL OF VIROLOGY//PSEUDORABIES VIRUS
8 1390 PARVOVIRUS B19//PORCINE CIRCOVIRUS TYPE 2//PARVOVIRUS
9 1804 ARTERIOGENESIS//COLLATERAL CIRCULATION//TRANSMYOCARDIAL LASER REVASCULARIZATION
10 1279 CANINE DISTEMPER VIRUS//MORBILLIVIRUS//SUBACUTE SCLEROSING PANENCEPHALITIS

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