Class information for:
Level 1: MOL MED GENE THER Y UNIT//ADENOVIRUS//HELPER DEPENDENT ADENOVIRAL VECTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6997 1418 43.4 85%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
419 3       ADENOVIRUS//MERKEL CELL CARCINOMA//GENE THERAPY 28518
564 2             GENE THERAPY//ADENOVIRUS//HUMAN GENE THERAPY 14456
6997 1                   MOL MED GENE THER Y UNIT//ADENOVIRUS//HELPER DEPENDENT ADENOVIRAL VECTOR 1418

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL MED GENE THER Y UNIT address 393648 2% 63% 29
2 ADENOVIRUS authKW 299224 19% 5% 265
3 HELPER DEPENDENT ADENOVIRAL VECTOR authKW 204146 1% 59% 16
4 HELPER DEPENDENT ADENOVIRUS authKW 201855 1% 63% 15
5 GUTLESS authKW 174411 1% 90% 9
6 HUMAN GENE THERAPY journal 167455 11% 5% 161
7 HELPER DEPENDENT authKW 165629 1% 77% 10
8 ADENOVIRUS VECTOR authKW 149934 4% 11% 61
9 GENE THERAPY journal 115684 10% 4% 145
10 GUTLESS ADENOVIRUS authKW 107662 0% 100% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Medicine, Research & Experimental 14201 37% 0% 531
2 Biotechnology & Applied Microbiology 13554 41% 0% 588
3 Genetics & Heredity 10846 37% 0% 519
4 Virology 4644 14% 0% 200
5 Biochemistry & Molecular Biology 705 22% 0% 313
6 Biochemical Research Methods 182 5% 0% 67
7 Immunology 144 7% 0% 95
8 Transplantation 131 2% 0% 34
9 Neurosciences 112 8% 0% 111
10 Cell Biology 77 6% 0% 84

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL MED GENE THER Y UNIT 393648 2% 63% 29
2 MT STATES MED 48446 0% 75% 3
3 MOL CELLULAR ENGN 45962 1% 11% 19
4 MEDGENE THER EUT 43065 0% 100% 2
5 NEUROMUSCULAR GRP 33671 1% 12% 13
6 LIBIN GENE THER Y UNIT 32296 0% 50% 3
7 FERMENTAT CELL CULTURE 31315 0% 36% 4
8 HUMAN GENE THER Y 24919 2% 4% 28
9 ABT F MOL MED VIROL 21532 0% 100% 1
10 ANIM MED SURG SECT 21532 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN GENE THERAPY 167455 11% 5% 161
2 GENE THERAPY 115684 10% 4% 145
3 MOLECULAR THERAPY 32308 5% 2% 73
4 JOURNAL OF GENE MEDICINE 16637 2% 2% 33
5 CURRENT GENE THERAPY 5635 1% 2% 12
6 JOURNAL OF VIROLOGY 5536 7% 0% 102
7 HUMAN GENE THERAPY METHODS 3233 0% 3% 5
8 CURRENT OPINION IN MOLECULAR THERAPEUTICS 1980 1% 1% 9
9 CANCER GENE THERAPY 1561 1% 1% 12
10 CYTOTECHNOLOGY 1200 1% 1% 11

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ADENOVIRUS 299224 19% 5% 265 Search ADENOVIRUS Search ADENOVIRUS
2 HELPER DEPENDENT ADENOVIRAL VECTOR 204146 1% 59% 16 Search HELPER+DEPENDENT+ADENOVIRAL+VECTOR Search HELPER+DEPENDENT+ADENOVIRAL+VECTOR
3 HELPER DEPENDENT ADENOVIRUS 201855 1% 63% 15 Search HELPER+DEPENDENT+ADENOVIRUS Search HELPER+DEPENDENT+ADENOVIRUS
4 GUTLESS 174411 1% 90% 9 Search GUTLESS Search GUTLESS
5 HELPER DEPENDENT 165629 1% 77% 10 Search HELPER+DEPENDENT Search HELPER+DEPENDENT
6 ADENOVIRUS VECTOR 149934 4% 11% 61 Search ADENOVIRUS+VECTOR Search ADENOVIRUS+VECTOR
7 GUTLESS ADENOVIRUS 107662 0% 100% 5 Search GUTLESS+ADENOVIRUS Search GUTLESS+ADENOVIRUS
8 GENE THERAPY 102452 18% 2% 262 Search GENE+THERAPY Search GENE+THERAPY
9 ADENOVIRAL VECTOR 93350 4% 8% 55 Search ADENOVIRAL+VECTOR Search ADENOVIRAL+VECTOR
10 GUTLESS VECTORS 76899 0% 71% 5 Search GUTLESS+VECTORS Search GUTLESS+VECTORS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 DORMOND, E , PERRIER, M , KAMEN, A , (2009) FROM THE FIRST TO THE THIRD GENERATION ADENOVIRAL VECTOR: WHAT PARAMETERS ARE GOVERNING THE PRODUCTION YIELD?.BIOTECHNOLOGY ADVANCES. VOL. 27. ISSUE 2. P. 133-144 96 85% 21
2 PALMER, DJ , NG, P , (2005) HELPER-DEPENDENT ADENOVIRAL VECTORS FOR GENE THERAPY.HUMAN GENE THERAPY. VOL. 16. ISSUE 1. P. 1-16 75 84% 99
3 SEGURA, MM , ALBA, R , BOSCH, A , CHILLON, M , (2008) ADVANCES IN HELPER-DEPENDENT ADENOVIRAL VECTOR RESEARCH.CURRENT GENE THERAPY. VOL. 8. ISSUE 4. P. 222-235 94 65% 29
4 SILVA, AC , PEIXOTO, C , LUCAS, T , KUPPERS, C , CRUZ, PE , ALVES, PM , KOCHANEK, S , (2010) ADENOVIRUS VECTOR PRODUCTION AND PURIFICATION.CURRENT GENE THERAPY. VOL. 10. ISSUE 6. P. 437-455 91 62% 8
5 SCHAGEN, FHE , OSSEVOORT, M , TOES, REM , HOEBEN, RC , (2004) IMMUNE RESPONSES AGAINST ADENOVIRAL VECTORS AND THEIR TRANSGENE PRODUCTS: A REVIEW OF STRATEGIES FOR EVASION.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 50. ISSUE 1. P. 51-70 107 54% 60
6 ALBA, R , BOSCH, A , CHILLON, M , (2005) GUTLESS ADENOVIRUS: LAST-GENERATION ADENOVIRUS FOR GENE THERAPY.GENE THERAPY. VOL. 12. ISSUE . P. S18-S27 73 65% 103
7 COTS, D , BOSCH, A , CHILLON, M , (2013) HELPER DEPENDENT ADENOVIRUS VECTORS: PROGRESS AND FUTURE PROSPECTS.CURRENT GENE THERAPY. VOL. 13. ISSUE 5. P. 370-381 75 58% 4
8 PARKS, RJ , EVELEGH, CM , GRAHAM, FL , (1999) USE OF HELPER-DEPENDENT ADENOVIRAL VECTORS OF ALTERNATIVE SEROTYPES PERMITS REPEAT VECTOR ADMINISTRATION.GENE THERAPY. VOL. 6. ISSUE 9. P. 1565 -1573 60 87% 79
9 VETRINI, F , NG, P , (2011) LIVER-DIRECTED GENE THERAPY WITH HELPER-DEPENDENT ADENOVIRAL VECTORS: CURRENT STATE OF THE ART AND FUTURE CHALLENGES.CURRENT PHARMACEUTICAL DESIGN. VOL. 17. ISSUE 24. P. 2488-2499 72 52% 10
10 HITT, MM , GRAHAM, FL , (2000) ADENOVIRUS VECTORS FOR HUMAN GENE THERAPY.ADVANCES IN VIRUS RESEARCH, VOL 55. VOL. 55. ISSUE . P. 479-505 77 58% 51

Classes with closest relation at Level 1


Rank Class id link
1 3599 ADENOVIRUS//COXSACKIE ADENOVIRUS RECEPTOR//HUMAN GENE THER Y
2 16206 GENE MED GRP//GENEMED GRP//EXPT TREATMENT CYST FIBROSIS
3 25514 HERPES SIMPLEX VIRUS VECTOR//W ROXBURY VA HOSP//HELPER VIRUS FREE PACKAGING
4 25097 INSULIN GENE THERAPY//ENDOCRINOL METAB SECT 111//INSULIN STORAGE
5 9238 RESTENOSIS//GENE THERAPY//LOCAL DRUG DELIVERY
6 10370 PORCINE ADENOVIRUS//DEV GENOM GRP//NUCLEAR FACTOR I
7 3940 SUICIDE GENE THERAPY//CYTOSINE DEAMINASE//HERPES SIMPLEX VIRUS THYMIDINE KINASE
8 18301 NAKED PLASMID DNA//HYDRODYNAMICS BASED TRANSFECTION//HYDRODYNAMIC GENE DELIVERY
9 1257 ADENO ASSOCIATED VIRUS//AAV//POWELL GENE THER Y
10 3242 E1A//ADENOVIRUS E1A//E4ORF6

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