Class information for:
Level 2: GENE DELIVERY//CELL PENETRATING PEPTIDE//CATIONIC LIPID

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
476 15822 45.7 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
227 3       MICRORNA//MIRNA//GENE DELIVERY 49432
476 2             GENE DELIVERY//CELL PENETRATING PEPTIDE//CATIONIC LIPID 15822
168 1                   GENE DELIVERY//POLYETHYLENIMINE//POLYPLEX 4046
385 1                   SIRNA//RNA INTERFERENCE//RNAI 3552
2061 1                   CELL PENETRATING PEPTIDE//PROTEIN TRANSDUCTION DOMAIN//PROTEIN TRANSDUCTION 2370
2198 1                   CATIONIC LIPID//CATIONIC LIPOSOMES//LIPOPLEX 2326
3573 1                   DNA VACCINE//DNA IMMUNIZATION//DNA VACCINATION 1955
18301 1                   NAKED PLASMID DNA//HYDRODYNAMICS BASED TRANSFECTION//HYDRODYNAMIC GENE DELIVERY 557
21247 1                   MRNA DELIVERY//LIPIDOID//MRNA VACCINE 427
26051 1                   CALCIUM PHOSPHATE NANOPARTICLES//CHARGE CONVERSIONAL POLYMER//NANOTECHNOL DRUG DELIVERY 264
29308 1                   PCL FILM//PELGE//POLYD L LACTIDE CO GLYCOLIDE 189
32650 1                   SCIENTIST//DISTANT TRANSFECTION//DNA RETARDATION TRANSFECTION 136

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 GENE DELIVERY authKW 1061760 8% 42% 1305
2 CELL PENETRATING PEPTIDE authKW 782176 4% 62% 660
3 CATIONIC LIPID authKW 509846 2% 68% 388
4 SIRNA authKW 469916 7% 23% 1066
5 NON VIRAL VECTOR authKW 417180 3% 52% 416
6 POLYETHYLENIMINE authKW 379150 3% 42% 473
7 POLYPLEX authKW 352999 2% 72% 255
8 CATIONIC LIPOSOMES authKW 345728 2% 50% 362
9 TRANSFECTION authKW 305024 5% 21% 753
10 LIPOPLEX authKW 303201 1% 67% 234

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Medicine, Research & Experimental 27003 16% 1% 2567
2 Materials Science, Biomaterials 22443 6% 1% 1018
3 Biotechnology & Applied Microbiology 15473 14% 0% 2277
4 Biochemistry & Molecular Biology 15234 29% 0% 4518
5 Pharmacology & Pharmacy 14121 19% 0% 3066
6 Genetics & Heredity 7490 10% 0% 1631
7 Chemistry, Multidisciplinary 6155 15% 0% 2428
8 Biophysics 4097 7% 0% 1087
9 Engineering, Biomedical 3531 4% 0% 679
10 Biochemical Research Methods 2901 5% 0% 861

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SYST BASED DRUG 44652 0% 70% 33
2 PHARMACEUT BIOPHARM 43802 0% 29% 79
3 CONTROLLED CHEM DELIVERY 40403 0% 33% 63
4 MOL DESIGN PHARMACEUT 37303 0% 41% 47
5 CHIM GENET 37260 0% 54% 36
6 PHARMACEUT PHARMACEUT CHEM 35793 1% 14% 138
7 BIOMED POLYMERS 35567 1% 15% 127
8 ANTIVIRAL GENE THER Y UNIT 32713 0% 57% 30
9 CLIN VASC REGENERAT 30892 0% 70% 23
10 CHEM BIOL PHARMACEUT CHEM 28578 0% 46% 32

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CONTROLLED RELEASE 106229 4% 9% 642
2 JOURNAL OF GENE MEDICINE 86790 2% 18% 252
3 BIOCONJUGATE CHEMISTRY 73684 3% 9% 438
4 GENE THERAPY 63705 2% 9% 361
5 MOLECULAR THERAPY 46272 2% 8% 293
6 MOLECULAR PHARMACEUTICS 33178 1% 7% 234
7 JOURNAL OF DRUG TARGETING 21390 1% 8% 132
8 BIOMATERIALS 21366 3% 3% 413
9 BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 18316 2% 4% 246
10 HUMAN GENE THERAPY 17217 1% 5% 174

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 GENE DELIVERY 1061760 8% 42% 1305 Search GENE+DELIVERY Search GENE+DELIVERY
2 CELL PENETRATING PEPTIDE 782176 4% 62% 660 Search CELL+PENETRATING+PEPTIDE Search CELL+PENETRATING+PEPTIDE
3 CATIONIC LIPID 509846 2% 68% 388 Search CATIONIC+LIPID Search CATIONIC+LIPID
4 SIRNA 469916 7% 23% 1066 Search SIRNA Search SIRNA
5 NON VIRAL VECTOR 417180 3% 52% 416 Search NON+VIRAL+VECTOR Search NON+VIRAL+VECTOR
6 POLYETHYLENIMINE 379150 3% 42% 473 Search POLYETHYLENIMINE Search POLYETHYLENIMINE
7 POLYPLEX 352999 2% 72% 255 Search POLYPLEX Search POLYPLEX
8 CATIONIC LIPOSOMES 345728 2% 50% 362 Search CATIONIC+LIPOSOMES Search CATIONIC+LIPOSOMES
9 TRANSFECTION 305024 5% 21% 753 Search TRANSFECTION Search TRANSFECTION
10 LIPOPLEX 303201 1% 67% 234 Search LIPOPLEX Search LIPOPLEX

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MINTZER, MA , SIMANEK, EE , (2009) NONVIRAL VECTORS FOR GENE DELIVERY.CHEMICAL REVIEWS. VOL. 109. ISSUE 2. P. 259 -302 316 60% 1074
2 LACHELT, U , WAGNER, E , (2015) NUCLEIC ACID THERAPEUTICS USING POLYPLEXES: A JOURNEY OF 50 YEARS (AND BEYOND).CHEMICAL REVIEWS. VOL. 115. ISSUE 19. P. 11043 -11078 339 66% 55
3 COPOLOVICI, DM , LANGEL, K , ERISTE, E , LANGEL, U , (2014) CELL-PENETRATING PEPTIDES: DESIGN, SYNTHESIS, AND APPLICATIONS.ACS NANO. VOL. 8. ISSUE 3. P. 1972 -1994 154 71% 144
4 BECHARA, C , SAGAN, S , (2013) CELL-PENETRATING PEPTIDES: 20 YEARS LATER, WHERE DO WE STAND?.FEBS LETTERS. VOL. 587. ISSUE 12. P. 1693 -1702 140 85% 174
5 YIN, H , KANASTY, RL , ELTOUKHY, AA , VEGAS, AJ , DORKIN, JR , ANDERSON, DG , (2014) NON-VIRAL VECTORS FOR GENE-BASED THERAPY.NATURE REVIEWS GENETICS. VOL. 15. ISSUE 8. P. 541 -555 99 67% 382
6 ZHI, DF , ZHANG, SB , CUI, SH , ZHAO, YA , WANG, YH , ZHAO, DF , (2013) THE HEADGROUP EVOLUTION OF CATIONIC LIPIDS FOR GENE DELIVERY.BIOCONJUGATE CHEMISTRY. VOL. 24. ISSUE 4. P. 487 -519 180 79% 69
7 BAJAJ, A , BHATTACHARYA, S , (2009) ADVANCES IN GENE DELIVERY THROUGH MOLECULAR DESIGN OF CATIONIC LIPIDS.CHEMICAL COMMUNICATIONS. VOL. . ISSUE 31. P. 4632 -4656 200 75% 154
8 PASSIRANI, C , VONARBOURG, A , CLAVREUL, A , BENOIT, JP , MORILLE, M , (2008) PROGRESS IN DEVELOPING CATIONIC VECTORS FOR NON-VIRAL SYSTEMIC GENE THERAPY AGAINST CANCER.BIOMATERIALS. VOL. 29. ISSUE 24-25. P. 3477 -3496 175 62% 420
9 YUE, YN , WU, C , (2013) PROGRESS AND PERSPECTIVES IN DEVELOPING POLYMERIC VECTORS FOR IN VITRO GENE DELIVERY.BIOMATERIALS SCIENCE. VOL. 1. ISSUE 2. P. 152-170 165 76% 58
10 NEU, M , FISCHER, D , KISSEL, T , (2005) RECENT ADVANCES IN RATIONAL GENE TRANSFER VECTOR DESIGN BASED ON POLY(ETHYLENE IMINE) AND ITS DERIVATIVES.JOURNAL OF GENE MEDICINE. VOL. 7. ISSUE 8. P. 992-1009 130 86% 537

Classes with closest relation at Level 2


Rank Class id link
1 3055 PIRNA//PIWI//PIWI INTERACTING RNA
2 147 SOLID LIPID NANOPARTICLES//POLYMERIC MICELLES//LIPOSOMES
3 564 GENE THERAPY//ADENOVIRUS//HUMAN GENE THERAPY
4 2441 ELECTROPORATION//ELECTROCHEMOTHERAPY//ELECTROPERMEABILIZATION
5 2904 PROTEIN CORONA//BIONANO INTERACT//CARRIER ERYTHROCYTES
6 962 DENDRIMERS//HYPERBRANCHED POLYMER//HYPERBRANCHED
7 1240 CHITOSAN//CHITIN//CHITOSANASE
8 1525 ADJUVANT//ISCOM//VACCINE
9 3012 MANNOSE RECEPTOR//ENDO180//ASIALOGLYCOPROTEIN RECEPTOR
10 389 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//OLIGONUCLEOTIDES//PEPTIDE NUCLEIC ACID

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