Class information for:
Level 1: ADENO ASSOCIATED VIRUS//AAV//POWELL GENE THER Y

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1257 2758 48.1 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
419 3       ADENOVIRUS//MERKEL CELL CARCINOMA//GENE THERAPY 28518
564 2             GENE THERAPY//ADENOVIRUS//HUMAN GENE THERAPY 14456
1257 1                   ADENO ASSOCIATED VIRUS//AAV//POWELL GENE THER Y 2758

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADENO ASSOCIATED VIRUS authKW 1614193 15% 35% 414
2 AAV authKW 927837 8% 40% 210
3 POWELL GENE THER Y address 485170 4% 37% 119
4 GENE THER Y address 419605 12% 12% 319
5 CELLULAR MOL THER Y address 311983 2% 46% 61
6 AAV VECTORS authKW 264096 2% 47% 51
7 MOLECULAR THERAPY journal 232815 10% 8% 273
8 GENE THER Y PROGRAM address 223210 4% 19% 104
9 HUMAN GENE THERAPY journal 204180 9% 7% 248
10 HUMAN GENE THERAPY METHODS journal 173377 2% 31% 51

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Virology 36656 28% 0% 768
2 Medicine, Research & Experimental 32486 41% 0% 1117
3 Biotechnology & Applied Microbiology 24077 40% 0% 1095
4 Genetics & Heredity 21914 37% 0% 1028
5 Biochemistry & Molecular Biology 842 18% 0% 510
6 Hematology 429 5% 0% 127
7 Biochemical Research Methods 150 3% 0% 95
8 Cell Biology 76 5% 0% 135
9 Cell & Tissue Engineering 25 0% 0% 10
10 Neurosciences 12 4% 0% 114

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 POWELL GENE THER Y 485170 4% 37% 119
2 GENE THER Y 419605 12% 12% 319
3 CELLULAR MOL THER Y 311983 2% 46% 61
4 GENE THER Y PROGRAM 223210 4% 19% 104
5 CELLULAR MOL THER EUT 111227 1% 30% 34
6 UNC GENE THER Y 98611 1% 64% 14
7 GENET THER EUT 92450 1% 21% 39
8 EXCELLENCE REGENERAT HLTH BIOTECHNOL 85147 0% 77% 10
9 U649 72445 0% 55% 12
10 ABRAMSON 310A 55349 0% 100% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR THERAPY 232815 10% 8% 273
2 HUMAN GENE THERAPY 204180 9% 7% 248
3 HUMAN GENE THERAPY METHODS 173377 2% 31% 51
4 GENE THERAPY 125840 8% 5% 211
5 MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT 62230 1% 18% 32
6 JOURNAL OF VIROLOGY 53281 16% 1% 437
7 JOURNAL OF GENE MEDICINE 23745 2% 4% 55
8 CURRENT GENE THERAPY 23288 1% 6% 34
9 HUMAN GENE THERAPY CLINICAL DEVELOPMENT 8732 0% 10% 8
10 VIROLOGY 7460 4% 1% 113

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ADENO ASSOCIATED VIRUS 1614193 15% 35% 414 Search ADENO+ASSOCIATED+VIRUS Search ADENO+ASSOCIATED+VIRUS
2 AAV 927837 8% 40% 210 Search AAV Search AAV
3 AAV VECTORS 264096 2% 47% 51 Search AAV+VECTORS Search AAV+VECTORS
4 REP78 155666 1% 94% 15 Search REP78 Search REP78
5 ADENO ASSOCIATED VIRUS AAV 139948 1% 45% 28 Search ADENO+ASSOCIATED+VIRUS+AAV Search ADENO+ASSOCIATED+VIRUS+AAV
6 ADENO ASSOCIATED VIRUS TYPE 2 133626 0% 93% 13 Search ADENO+ASSOCIATED+VIRUS+TYPE+2 Search ADENO+ASSOCIATED+VIRUS+TYPE+2
7 ADENO ASSOCIATED VIRUS VECTOR 117244 1% 38% 28 Search ADENO+ASSOCIATED+VIRUS+VECTOR Search ADENO+ASSOCIATED+VIRUS+VECTOR
8 GENE THERAPY 115934 14% 3% 389 Search GENE+THERAPY Search GENE+THERAPY
9 RAAV 111574 1% 31% 33 Search RAAV Search RAAV
10 AAV SEROTYPES 78716 0% 89% 8 Search AAV+SEROTYPES Search AAV+SEROTYPES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 SAMULSKI, RJ , MUZYCZKA, N , (2014) AAV-MEDIATED GENE THERAPY FOR RESEARCH AND THERAPEUTIC PURPOSES.ANNUAL REVIEW OF VIROLOGY, VOL 1. VOL. 1. ISSUE . P. 427 -451 156 78% 27
2 BUNING, H , PERABO, L , COUTELLE, O , QUADT-HUMME, S , HALLEK, M , (2008) RECENT DEVELOPMENTS IN ADENO-ASSOCIATED VIRUS VECTOR TECHNOLOGY.JOURNAL OF GENE MEDICINE. VOL. 10. ISSUE 7. P. 717-733 153 91% 77
3 BALAKRISHNAN, B , JAYANDHARAN, GR , (2014) BASIC BIOLOGY OF ADENO-ASSOCIATED VIRUS (AAV) VECTORS USED IN GENE THERAPY.CURRENT GENE THERAPY. VOL. 14. ISSUE 2. P. 86 -100 151 85% 9
4 MITCHELL, AM , NICOLSON, SC , WARISCHALK, JK , SAMULSKI, RJ , (2010) AAV'S ANATOMY: ROADMAP FOR OPTIMIZING VECTORS FOR TRANSLATIONAL SUCCESS.CURRENT GENE THERAPY. VOL. 10. ISSUE 5. P. 319 -340 188 71% 38
5 DISMUKE, DJ , TENENBAUM, L , SAMULSKI, RJ , (2013) BIOSAFETY OF RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS.CURRENT GENE THERAPY. VOL. 13. ISSUE 6. P. 434-452 170 68% 20
6 MINGOZZI, F , HIGH, KA , (2013) IMMUNE RESPONSES TO AAV VECTORS: OVERCOMING BARRIERS TO SUCCESSFUL GENE THERAPY.BLOOD. VOL. 122. ISSUE 1. P. 23-36 103 78% 113
7 SCHULTZ, BR , CHAMBERLAIN, JS , (2008) RECOMBINANT ADENO-ASSOCIATED VIRUS TRANSDUCTION AND INTEGRATION.MOLECULAR THERAPY. VOL. 16. ISSUE 7. P. 1189 -1199 133 92% 64
8 WU, ZJ , ASOKAN, A , SAMULSKI, RJ , (2006) ADENO-ASSOCIATED VIRUS SEROTYPES: VECTOR TOOLKIT FOR HUMAN GENE THERAPY.MOLECULAR THERAPY. VOL. 14. ISSUE 3. P. 316-327 105 91% 333
9 HENCKAERTS, E , LINDEN, RM , (2010) ADENO-ASSOCIATED VIRUS: A KEY TO THE HUMAN GENOME?.FUTURE VIROLOGY. VOL. 5. ISSUE 5. P. 555-574 142 79% 23
10 GRIEGER, JC , SAMULSKI, RJ , (2012) ADENO-ASSOCIATED VIRUS VECTOROLOGY, MANUFACTURING, AND CLINICAL APPLICATIONS.METHODS IN ENZYMOLOGY, VOL 507: GENE TRANSFER VECTORS FOR CLINICAL APPLICATION. VOL. 507. ISSUE . P. 229-254 105 85% 61

Classes with closest relation at Level 1


Rank Class id link
1 9747 LEBER CONGENITAL AMAUROSIS//RPE65//LEBERS CONGENITAL AMAUROSIS
2 9946 DENSOVIRUS//ALEUTIAN MINK DISEASE VIRUS//U375
3 16206 GENE MED GRP//GENEMED GRP//EXPT TREATMENT CYST FIBROSIS
4 6997 MOL MED GENE THER Y UNIT//ADENOVIRUS//HELPER DEPENDENT ADENOVIRAL VECTOR
5 7211 FACTOR VIII//HEMOPHILIA A//FACTOR VIIIA
6 25514 HERPES SIMPLEX VIRUS VECTOR//W ROXBURY VA HOSP//HELPER VIRUS FREE PACKAGING
7 16462 MOL ORTHOPAED//EXPT ORTHOPAED//RAAV GENE TRANSFER
8 25097 INSULIN GENE THERAPY//ENDOCRINOL METAB SECT 111//INSULIN STORAGE
9 18301 NAKED PLASMID DNA//HYDRODYNAMICS BASED TRANSFECTION//HYDRODYNAMIC GENE DELIVERY
10 2246 LENTIVIRAL VECTOR//EXPT HEMATOL//RETROVIRAL VECTOR

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