Class information for:
Level 1: RAD P53//RECOMBINANT ADENOVIRUS P53//ADENOVIRAL MEDIATED INTERFERON ALPHA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
16830 633 40.5 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
419 3       ADENOVIRUS//MERKEL CELL CARCINOMA//GENE THERAPY 28518
564 2             GENE THERAPY//ADENOVIRUS//HUMAN GENE THERAPY 14456
16830 1                   RAD P53//RECOMBINANT ADENOVIRUS P53//ADENOVIRAL MEDIATED INTERFERON ALPHA 633

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RAD P53 authKW 241189 1% 100% 5
2 RECOMBINANT ADENOVIRUS P53 authKW 241189 1% 100% 5
3 ADENOVIRAL MEDIATED INTERFERON ALPHA authKW 192951 1% 100% 4
4 P53 GENE THERAPY authKW 173651 1% 60% 6
5 GENE THERAPY authKW 117139 30% 1% 187
6 B7 1 COSTIMULATORY MOLECULE authKW 108534 0% 75% 3
7 P53 ADENOVIRUS authKW 108534 0% 75% 3
8 SECT THORAC MOL ONCOL address 107244 2% 17% 13
9 AD5CMV P53 authKW 96476 0% 100% 2
10 ADENOVIRAL MEDIATED INTERFERON ALPHA TREATMENT authKW 96476 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 7677 57% 0% 358
2 Medicine, Research & Experimental 2789 25% 0% 160
3 Genetics & Heredity 1689 22% 0% 141
4 Biotechnology & Applied Microbiology 1525 22% 0% 137
5 Urology & Nephrology 49 3% 0% 21
6 Obstetrics & Gynecology 38 3% 0% 20
7 Radiology, Nuclear Medicine & Medical Imaging 29 4% 0% 25
8 Gastroenterology & Hepatology 24 3% 0% 17
9 Cell Biology 20 5% 0% 32
10 Biochemistry & Molecular Biology 20 10% 0% 61

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SECT THORAC MOL ONCOL 107244 2% 17% 13
2 UNIT 0018 5 96476 0% 100% 2
3 GENET MOL CARDIOL LIM13 72354 0% 50% 3
4 BEIJING PRINTED ELECT ENGN TECHNOL 48238 0% 100% 1
5 BIOTECHNOL BIOASSAYS 48238 0% 100% 1
6 CANC 338 48238 0% 100% 1
7 CANC SAO PAULO MED 48238 0% 100% 1
8 CANV MED BIOPHYS 48238 0% 100% 1
9 CLIN MOL MED MOL DIAGNOST 48238 0% 100% 1
10 DUKE THORAC ONCOL PROGRAM 48238 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER GENE THERAPY 94679 10% 3% 62
2 HUMAN GENE THERAPY 6974 3% 1% 22
3 TUMOR TARGETING 6650 0% 7% 2
4 GENE THERAPY 2750 2% 0% 15
5 CLINICAL CANCER RESEARCH 2337 4% 0% 27
6 MOLECULAR THERAPY 2280 2% 0% 13
7 CURRENT OPINION IN MOLECULAR THERAPEUTICS 1977 1% 1% 6
8 ANTI-CANCER DRUGS 1462 2% 0% 10
9 INTERNATIONAL JOURNAL OF ONCOLOGY 1273 3% 0% 16
10 CHINESE JOURNAL OF CANCER RESEARCH 1187 1% 1% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RAD P53 241189 1% 100% 5 Search RAD+P53 Search RAD+P53
2 RECOMBINANT ADENOVIRUS P53 241189 1% 100% 5 Search RECOMBINANT+ADENOVIRUS+P53 Search RECOMBINANT+ADENOVIRUS+P53
3 ADENOVIRAL MEDIATED INTERFERON ALPHA 192951 1% 100% 4 Search ADENOVIRAL+MEDIATED+INTERFERON+ALPHA Search ADENOVIRAL+MEDIATED+INTERFERON+ALPHA
4 P53 GENE THERAPY 173651 1% 60% 6 Search P53+GENE+THERAPY Search P53+GENE+THERAPY
5 GENE THERAPY 117139 30% 1% 187 Search GENE+THERAPY Search GENE+THERAPY
6 B7 1 COSTIMULATORY MOLECULE 108534 0% 75% 3 Search B7+1+COSTIMULATORY+MOLECULE Search B7+1+COSTIMULATORY+MOLECULE
7 P53 ADENOVIRUS 108534 0% 75% 3 Search P53+ADENOVIRUS Search P53+ADENOVIRUS
8 AD5CMV P53 96476 0% 100% 2 Search AD5CMV+P53 Search AD5CMV+P53
9 ADENOVIRAL MEDIATED INTERFERON ALPHA TREATMENT 96476 0% 100% 2 Search ADENOVIRAL+MEDIATED+INTERFERON+ALPHA+TREATMENT Search ADENOVIRAL+MEDIATED+INTERFERON+ALPHA+TREATMENT
10 PCLPG 96476 0% 100% 2 Search PCLPG Search PCLPG

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 TAZAWA, H , KAGAWA, S , FUJIWARA, T , (2013) ADVANCES IN ADENOVIRUS-MEDIATED P53 CANCER GENE THERAPY.EXPERT OPINION ON BIOLOGICAL THERAPY. VOL. 13. ISSUE 11. P. 1569-1583 50 51% 21
2 GABRILOVICH, DI , (2006) INGN 201 (ADVEXIN (R)): ADENOVIRAL P53 GENE THERAPY FOR CANCER.EXPERT OPINION ON BIOLOGICAL THERAPY. VOL. 6. ISSUE 8. P. 823-832 34 51% 35
3 HOROWITZ, J , (1999) ADENOVIRUS-MEDIATED P53 GENE THERAPY: OVERVIEW OF PRECLINICAL STUDIES AND POTENTIAL CLINICAL APPLICATIONS.CURRENT OPINION IN MOLECULAR THERAPEUTICS. VOL. 1. ISSUE 4. P. 500 -509 36 59% 46
4 NIELSEN, LL , MANEVAL, DC , (1998) P53 TUMOR SUPPRESSOR GENE THERAPY FOR CANCER.CANCER GENE THERAPY. VOL. 5. ISSUE 1. P. 52 -63 37 47% 151
5 CHEN, GX , ZHANG, S , HE, XH , LIU, SY , MA, C , ZOU, XP , (2014) CLINICAL UTILITY OF RECOMBINANT ADENOVIRAL HUMAN P53 GENE THERAPY: CURRENT PERSPECTIVES.ONCOTARGETS AND THERAPY. VOL. 7. ISSUE . P. 1901 -1909 28 39% 17
6 ROTH, JA , (2006) ADENOVIRUS P53 GENE THERAPY.EXPERT OPINION ON BIOLOGICAL THERAPY. VOL. 6. ISSUE 1. P. 55-61 25 49% 75
7 LIU, S , CHEN, P , HU, M , TAO, Y , CHEN, L , LIU, H , WANG, J , LUO, J , GAO, G , (2013) RANDOMIZED, CONTROLLED PHASE II STUDY OF POST-SURGERY RADIOTHERAPY COMBINED WITH RECOMBINANT ADENOVIRAL HUMAN P53 GENE THERAPY IN TREATMENT OF ORAL CANCER.CANCER GENE THERAPY. VOL. 20. ISSUE 6. P. 375-378 17 63% 7
8 VATTEMI, E , HARPER, M , CLAUDIO, PP , (2009) CONTUSUGENE LADENOVEC APOPTOSIS INDUCER CANCER GENE THERAPY.DRUGS OF THE FUTURE. VOL. 34. ISSUE 3. P. 183-188 23 53% 0
9 SWISHER, SG , ROTH, JA , NEMUNAITIS, J , LAWRENCE, DD , KEMP, BL , CARRASCO, CH , CONNORS, DG , EL-NAGGAR, AK , FOSSELLA, F , GLISSON, BS , ET AL (1999) ADENOVIRUS-MEDIATED P53 GENE TRANSFER IN ADVANCED NON-SMALL-CELL LUNG CANCER.JOURNAL OF THE NATIONAL CANCER INSTITUTE. VOL. 91. ISSUE 9. P. 763-771 19 54% 295
10 FUJIWARA, T , TANAKA, N , KANAZAWA, S , OHTANI, S , SAIJO, Y , NUKIWA, T , YOSHIMURA, K , SATO, T , ETO, Y , CHADA, S , ET AL (2006) MULTICENTER PHASE I STUDY OF REPEATED INTRATUMORAL DELIVERY OF ADENOVIRAL P53 IN PATIENTS WITH ADVANCED NON-SMALL-CELL LUNG CANCER.JOURNAL OF CLINICAL ONCOLOGY. VOL. 24. ISSUE 11. P. 1689-1699 18 58% 51

Classes with closest relation at Level 1


Rank Class id link
1 3940 SUICIDE GENE THERAPY//CYTOSINE DEAMINASE//HERPES SIMPLEX VIRUS THYMIDINE KINASE
2 1581 P53//P53 GENE//ONCOGENE
3 28833 GENETIC RADIOTHERAPY//TNFERADE//CARG ELEMENTS
4 1181 ONCOLYTIC VIRUS//ONCOLYTIC ADENOVIRUS//VIROTHERAPY
5 6997 MOL MED GENE THER Y UNIT//ADENOVIRUS//HELPER DEPENDENT ADENOVIRAL VECTOR
6 9064 P21//P21WAF1 CIP1//P21WAF1
7 30791 PUMA//PUMA GENE//P53 UPREGULATED MODULATOR OF APOPTOSIS PUMA
8 3599 ADENOVIRUS//COXSACKIE ADENOVIRUS RECEPTOR//HUMAN GENE THER Y
9 8010 MUTANT P53//PRIMA 1//CP 31398
10 35768 QUIESCENT CELL//BORON TRACEDRUG//MILD TEMPERATURE HYPERTHERMIA

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