Class information for:
Level 1: GENE DELIVERY//POLYETHYLENIMINE//POLYPLEX

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
168 4046 46.3 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
227 3       MICRORNA//MIRNA//GENE DELIVERY 49432
476 2             GENE DELIVERY//CELL PENETRATING PEPTIDE//CATIONIC LIPID 15822
168 1                   GENE DELIVERY//POLYETHYLENIMINE//POLYPLEX 4046

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GENE DELIVERY authKW 1759962 21% 27% 849
2 POLYETHYLENIMINE authKW 1238997 11% 38% 432
3 POLYPLEX authKW 1124174 6% 65% 230
4 NON VIRAL GENE DELIVERY authKW 568438 4% 44% 171
5 NON VIRAL VECTOR authKW 548137 6% 30% 241
6 CATIONIC POLYMER authKW 277038 3% 31% 118
7 TRANSFECTION authKW 232356 8% 9% 332
8 PEI authKW 208663 2% 29% 97
9 TRANSFECTION EFFICIENCY authKW 206238 2% 33% 84
10 NON VIRAL authKW 173837 2% 31% 75

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Materials Science, Biomaterials 43034 17% 1% 694
2 Engineering, Biomedical 7601 11% 0% 457
3 Pharmacology & Pharmacy 6880 26% 0% 1036
4 Chemistry, Multidisciplinary 6132 27% 0% 1085
5 Polymer Science 5096 14% 0% 578
6 Medicine, Research & Experimental 4461 13% 0% 538
7 Biotechnology & Applied Microbiology 3208 13% 0% 531
8 Biochemistry & Molecular Biology 2343 23% 0% 946
9 Chemistry, Organic 2259 12% 0% 489
10 Nanoscience & Nanotechnology 1867 8% 0% 329

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SYST BASED DRUG 154253 1% 66% 31
2 CLIN VASC REGENERAT 120937 1% 70% 23
3 CONTROLLED CHEM DELIVERY 120685 1% 29% 55
4 PHARMACEUT BIOPHARM 112694 2% 23% 64
5 CHEM BIOL PHARMACEUT CHEM 111940 1% 46% 32
6 CHIM GENET 108189 1% 46% 31
7 BIOMED POLYMERS 102967 3% 13% 109
8 PHARMACEUT PHARMACEUT CHEM 101153 3% 11% 117
9 DIS BIOL INTEGRAT MED 53572 2% 10% 69
10 TRANSLAT TISSUE ENGN 52117 1% 22% 31

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CONTROLLED RELEASE 111768 8% 4% 332
2 BIOCONJUGATE CHEMISTRY 83460 6% 5% 235
3 JOURNAL OF GENE MEDICINE 64823 3% 8% 110
4 BIOMATERIALS 39600 7% 2% 281
5 BIOMACROMOLECULES 37437 5% 3% 183
6 GENE THERAPY 24896 3% 3% 114
7 MOLECULAR PHARMACEUTICS 22881 2% 3% 98
8 MACROMOLECULAR BIOSCIENCE 20919 2% 4% 75
9 JOURNAL OF DRUG TARGETING 10641 1% 3% 47
10 INTERNATIONAL JOURNAL OF NANOMEDICINE 8100 1% 2% 59

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GENE DELIVERY 1759962 21% 27% 849 Search GENE+DELIVERY Search GENE+DELIVERY
2 POLYETHYLENIMINE 1238997 11% 38% 432 Search POLYETHYLENIMINE Search POLYETHYLENIMINE
3 POLYPLEX 1124174 6% 65% 230 Search POLYPLEX Search POLYPLEX
4 NON VIRAL GENE DELIVERY 568438 4% 44% 171 Search NON+VIRAL+GENE+DELIVERY Search NON+VIRAL+GENE+DELIVERY
5 NON VIRAL VECTOR 548137 6% 30% 241 Search NON+VIRAL+VECTOR Search NON+VIRAL+VECTOR
6 CATIONIC POLYMER 277038 3% 31% 118 Search CATIONIC+POLYMER Search CATIONIC+POLYMER
7 TRANSFECTION 232356 8% 9% 332 Search TRANSFECTION Search TRANSFECTION
8 PEI 208663 2% 29% 97 Search PEI Search PEI
9 TRANSFECTION EFFICIENCY 206238 2% 33% 84 Search TRANSFECTION+EFFICIENCY Search TRANSFECTION+EFFICIENCY
10 NON VIRAL 173837 2% 31% 75 Search NON+VIRAL Search NON+VIRAL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LACHELT, U , WAGNER, E , (2015) NUCLEIC ACID THERAPEUTICS USING POLYPLEXES: A JOURNEY OF 50 YEARS (AND BEYOND).CHEMICAL REVIEWS. VOL. 115. ISSUE 19. P. 11043 -11078 293 57% 55
2 MINTZER, MA , SIMANEK, EE , (2009) NONVIRAL VECTORS FOR GENE DELIVERY.CHEMICAL REVIEWS. VOL. 109. ISSUE 2. P. 259 -302 199 38% 1074
3 PACK, DW , HOFFMAN, AS , PUN, S , STAYTON, PS , (2005) DESIGN AND DEVELOPMENT OF POLYMERS FOR GENE DELIVERY.NATURE REVIEWS DRUG DISCOVERY. VOL. 4. ISSUE 7. P. 581-593 109 66% 1261
4 NEU, M , FISCHER, D , KISSEL, T , (2005) RECENT ADVANCES IN RATIONAL GENE TRANSFER VECTOR DESIGN BASED ON POLY(ETHYLENE IMINE) AND ITS DERIVATIVES.JOURNAL OF GENE MEDICINE. VOL. 7. ISSUE 8. P. 992-1009 120 79% 537
5 LI, L , WEI, YQ , GONG, CY , (2015) POLYMERIC NANOCARRIERS FOR NON-VIRAL GENE DELIVERY.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY. VOL. 11. ISSUE 5. P. 739 -770 166 59% 16
6 WAGNER, E , (2014) POLYMERS FOR NUCLEIC ACID TRANSFER-AN OVERVIEW.NONVIRAL VECTORS FOR GENE THERAPY LIPID- AND POLYMER-BASED GENE TRANSFER. VOL. 88. ISSUE . P. 231 -261 149 77% 11
7 YUE, YN , WU, C , (2013) PROGRESS AND PERSPECTIVES IN DEVELOPING POLYMERIC VECTORS FOR IN VITRO GENE DELIVERY.BIOMATERIALS SCIENCE. VOL. 1. ISSUE 2. P. 152-170 144 67% 58
8 WONG, SY , PELET, JM , PUTNAM, D , (2007) POLYMER SYSTEMS FOR GENE DELIVERY-PAST, PRESENT, AND FUTURE.PROGRESS IN POLYMER SCIENCE. VOL. 32. ISSUE 8-9. P. 799 -837 172 57% 247
9 LUNGWITZ, U , BREUNIG, M , BLUNK, T , GOPFERICH, A , (2005) POLYETHYLENIMINE-BASED NON-VIRAL GENE DELIVERY SYSTEMS.EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. VOL. 60. ISSUE 2. P. 247-266 128 65% 504
10 WAGNER, E , KLOECKNER, J , (2006) GENE DELIVERY USING POLYMER THERAPEUTICS.POLYMER THERAPEUTICS I: POLYMERS AS DRUGS, CONJUGATES AND GENE DELIVERY SYSTEMS. VOL. 192. ISSUE . P. 135 -173 141 78% 89

Classes with closest relation at Level 1


Rank Class id link
1 29308 PCL FILM//PELGE//POLYD L LACTIDE CO GLYCOLIDE
2 2198 CATIONIC LIPID//CATIONIC LIPOSOMES//LIPOPLEX
3 21247 MRNA DELIVERY//LIPIDOID//MRNA VACCINE
4 26051 CALCIUM PHOSPHATE NANOPARTICLES//CHARGE CONVERSIONAL POLYMER//NANOTECHNOL DRUG DELIVERY
5 36948 NANOMED TAIWAN//PRONECTIN//ENHANCED GENE EXPRESSION
6 16206 GENE MED GRP//GENEMED GRP//EXPT TREATMENT CYST FIBROSIS
7 4363 CHITOSAN//CHITOSAN NANOPARTICLES//TRIPOLYPHOSPHATE
8 18301 NAKED PLASMID DNA//HYDRODYNAMICS BASED TRANSFECTION//HYDRODYNAMIC GENE DELIVERY
9 3239 GEN BIOPHYS//DENDRIMERS//PAMAM DENDRIMER
10 13044 GENE ACTIVATED MATRIX//SKELETAL BIOTECH//SOLID PHASE DELIVERY

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