Class information for:
Level 1: CATIONIC LIPID//CATIONIC LIPOSOMES//LIPOPLEX

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2198 2326 41.1 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
227 3       MICRORNA//MIRNA//GENE DELIVERY 49432
476 2             GENE DELIVERY//CELL PENETRATING PEPTIDE//CATIONIC LIPID 15822
2198 1                   CATIONIC LIPID//CATIONIC LIPOSOMES//LIPOPLEX 2326

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CATIONIC LIPID authKW 2376733 14% 56% 321
2 CATIONIC LIPOSOMES authKW 1628732 13% 41% 301
3 LIPOPLEX authKW 1154955 8% 50% 175
4 TRANSFECTION authKW 296030 12% 8% 284
5 GENE DELIVERY authKW 250550 10% 8% 243
6 LIPOFECTION authKW 194214 2% 27% 54
7 GRP QUIM COLOIDAL SUPRAMOL address 158448 1% 93% 13
8 NONVIRAL GENE DELIVERY address 147660 1% 75% 15
9 DOTAP authKW 141489 1% 37% 29
10 CEMCA address 132330 1% 46% 22

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biophysics 3659 15% 0% 352
2 Biochemistry & Molecular Biology 3241 33% 0% 773
3 Pharmacology & Pharmacy 2836 22% 0% 515
4 Medicine, Research & Experimental 1693 11% 0% 257
5 Chemistry, Multidisciplinary 1642 19% 0% 452
6 Chemistry, Medicinal 1272 8% 0% 177
7 Biotechnology & Applied Microbiology 1105 11% 0% 245
8 Materials Science, Biomaterials 1046 4% 0% 87
9 Chemistry, Organic 835 10% 0% 234
10 Genetics & Heredity 651 8% 0% 193

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GRP QUIM COLOIDAL SUPRAMOL 158448 1% 93% 13
2 NONVIRAL GENE DELIVERY 147660 1% 75% 15
3 CEMCA 132330 1% 46% 22
4 PREMED UNIT 119326 0% 91% 10
5 LIPID SCI TECHNOL 105433 1% 27% 30
6 IBISA SYNNANOVECT PLATFORM 93752 0% 71% 10
7 SERV GENET MOL HISTOCOMPATIBILITE 78756 0% 100% 6
8 WOLFSON GENE THER Y CHILDHOOD DIS 67205 1% 39% 13
9 NANOTECHNOL CHEM BIOL 62533 0% 53% 9
10 MEMBRANE CELL BIOL 60188 1% 27% 17

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 34375 6% 2% 128
2 JOURNAL OF LIPOSOME RESEARCH 25786 1% 6% 34
3 BIOCONJUGATE CHEMISTRY 17183 3% 2% 81
4 GENE THERAPY 15872 3% 2% 69
5 JOURNAL OF GENE MEDICINE 12727 2% 3% 37
6 JOURNAL OF CONTROLLED RELEASE 9569 3% 1% 74
7 JOURNAL OF DRUG TARGETING 8592 1% 2% 32
8 MOLECULAR PHARMACEUTICS 5345 2% 1% 36
9 INTERNATIONAL JOURNAL OF PHARMACEUTICS 2792 3% 0% 59
10 CHEMISTRY AND PHYSICS OF LIPIDS 2299 1% 1% 24

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CATIONIC LIPID 2376733 14% 56% 321 Search CATIONIC+LIPID Search CATIONIC+LIPID
2 CATIONIC LIPOSOMES 1628732 13% 41% 301 Search CATIONIC+LIPOSOMES Search CATIONIC+LIPOSOMES
3 LIPOPLEX 1154955 8% 50% 175 Search LIPOPLEX Search LIPOPLEX
4 TRANSFECTION 296030 12% 8% 284 Search TRANSFECTION Search TRANSFECTION
5 GENE DELIVERY 250550 10% 8% 243 Search GENE+DELIVERY Search GENE+DELIVERY
6 LIPOFECTION 194214 2% 27% 54 Search LIPOFECTION Search LIPOFECTION
7 DOTAP 141489 1% 37% 29 Search DOTAP Search DOTAP
8 HELPER LIPID 123232 1% 72% 13 Search HELPER+LIPID Search HELPER+LIPID
9 DC CHOL 116931 1% 64% 14 Search DC+CHOL Search DC+CHOL
10 CATIONIC CHOLESTEROL 111178 1% 71% 12 Search CATIONIC+CHOLESTEROL Search CATIONIC+CHOLESTEROL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ZHI, DF , ZHANG, SB , CUI, SH , ZHAO, YA , WANG, YH , ZHAO, DF , (2013) THE HEADGROUP EVOLUTION OF CATIONIC LIPIDS FOR GENE DELIVERY.BIOCONJUGATE CHEMISTRY. VOL. 24. ISSUE 4. P. 487 -519 165 72% 69
2 BAJAJ, A , BHATTACHARYA, S , (2009) ADVANCES IN GENE DELIVERY THROUGH MOLECULAR DESIGN OF CATIONIC LIPIDS.CHEMICAL COMMUNICATIONS. VOL. . ISSUE 31. P. 4632 -4656 174 65% 154
3 JUNQUERA, E , AICART, E , (2014) CATIONIC LIPIDS AS TRANSFECTING AGENTS OF DNA IN GENE THERAPY.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 14. ISSUE 5. P. 649 -663 123 70% 23
4 ZHI, DF , ZHANG, SB , WANG, B , ZHAO, YN , YANG, BL , YU, SJ , (2010) TRANSFECTION EFFICIENCY OF CATIONIC LIPIDS WITH DIFFERENT HYDROPHOBIC DOMAINS IN GENE DELIVERY.BIOCONJUGATE CHEMISTRY. VOL. 21. ISSUE 4. P. 563 -577 90 85% 94
5 CARACCIOLO, G , AMENITSCH, H , (2012) CATIONIC LIPOSOME/DNA COMPLEXES: FROM STRUCTURE TO INTERACTIONS WITH CELLULAR MEMBRANES.EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. VOL. 41. ISSUE 10. P. 815 -829 94 82% 38
6 KARMALI, PP , CHAUDHURI, A , (2007) CATIONIC LIPOSOMES AS NON-VIRAL CARRIERS OF GENE MEDICINES: RESOLVED ISSUES, OPEN QUESTIONS, AND FUTURE PROMISES.MEDICINAL RESEARCH REVIEWS. VOL. 27. ISSUE 5. P. 696 -722 104 73% 166
7 KOYNOVA, R , TENCHOV, B , (2010) CATIONIC LIPIDS: MOLECULAR STRUCTURE/TRANSFECTION ACTIVITY RELATIONSHIPS AND INTERACTIONS WITH BIOMEMBRANES.NUCLEIC ACID TRANSFECTION. VOL. 296. ISSUE . P. 51-93 103 82% 13
8 SIMBERG, D , WEISMAN, S , TALMON, Y , BARENHOLZ, Y , (2004) DOTAP (AND OTHER CATIONIC LIPIDS): CHEMISTRY, BIOPHYSICS, AND TRANSFECTION.CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS. VOL. 21. ISSUE 4. P. 257 -317 127 68% 113
9 MADEIRA, C , LOURA, LMS , AIRES-BARROS, MR , PRIETO, M , (2011) FLUORESCENCE METHODS FOR LIPOPLEX CHARACTERIZATION.BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. VOL. 1808. ISSUE 11. P. 2694 -2705 97 84% 8
10 MA, BC , ZHANG, SB , JIANG, HM , ZHAO, BD , LV, HT , (2007) LIPOPLEX MORPHOLOGIES AND THEIR INFLUENCES ON TRANSFECTION EFFICIENCY IN GENE DELIVERY.JOURNAL OF CONTROLLED RELEASE. VOL. 123. ISSUE 3. P. 184 -194 81 82% 166

Classes with closest relation at Level 1


Rank Class id link
1 16206 GENE MED GRP//GENEMED GRP//EXPT TREATMENT CYST FIBROSIS
2 168 GENE DELIVERY//POLYETHYLENIMINE//POLYPLEX
3 21247 MRNA DELIVERY//LIPIDOID//MRNA VACCINE
4 31931 BAYERS JUNCTIONS//DNA MEMBRANE COMPLEXES//DNA MEMBRANE CONTACTS
5 32650 SCIENTIST//DISTANT TRANSFECTION//DNA RETARDATION TRANSFECTION
6 26932 IMMUNOPORATION//SINGLE DEAE GROUP//TANDEM DEAE GROUP
7 8956 DNA CONDENSATION//LIQUID CRYSTALLINE DISPERSIONS//HIGHER ORDER STRUCTURE OF DNA
8 12767 THERMOSENSITIVE LIPOSOMES//PH SENSITIVE LIPOSOMES//TEMPERATURE SENSITIVE LIPOSOMES
9 18301 NAKED PLASMID DNA//HYDRODYNAMICS BASED TRANSFECTION//HYDRODYNAMIC GENE DELIVERY
10 29308 PCL FILM//PELGE//POLYD L LACTIDE CO GLYCOLIDE

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