Class information for:
Level 2: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//OLIGONUCLEOTIDES//PEPTIDE NUCLEIC ACID

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
389 16949 35.1 76%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
183 3       APTAMER//G QUADRUPLEX//RIBOZYME 56307
389 2             NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//OLIGONUCLEOTIDES//PEPTIDE NUCLEIC ACID 16949
1458 1                   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//H PHOSPHONATES//BORANOPHOSPHATE 2652
2407 1                   ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT//ANTISENSE OLIGONUCLEOTIDES//ANTISENSE RESEARCH AND DEVELOPMENT 2255
3100 1                   TRIPLEX DNA//TRIPLEX//DNA TRIPLEX 2065
4600 1                   NUCLE ACID//SYNTHET BIOORGAN CHEM//NUCL ACID 1758
6706 1                   PEPTIDE NUCLEIC ACID//PNA//BIOMOL RECOGNIT 1453
9258 1                   OLIGONUCLEOTIDE PEPTIDE CONJUGATES//NUCLEOPEPTIDES//PEPTIDE OLIGONUCLEOTIDE CONJUGATE 1173
9408 1                   METAL MEDIATED BASE PAIRS//UNNATURAL BASE PAIRS//METALLO BASE PAIR 1158
9916 1                   NEWCAT//WOLFSON RAT STRUCT BASED DESIGN MOL DIAGNOST//CHEM BIOL PL CHEM 1107
13926 1                   BIOL MACROMOL STRUCT//SHEARED G CENTER DOT A PAIR//SHEARED A CENTER DOT C PAIR 804
17788 1                   NOVOSIBIRSK BIOORGAN CHEM//OLIGONUCLEOTIDE DERIVATIVES//PHOTOAFFINITY MODIFICATION 582
17844 1                   GILEAD IOCB//REVERSIBLE TERMINATOR//LIFE SCI SOLUT GRP 580
21062 1                   DNA ENCODED LIBRARY//DNA ENCODED CHEMICAL LIBRARY//TEMPLATED REACTIONS 435
23595 1                   4 THIOTHYMIDINE//ORGAN BIOMIMET CHEM//2 DEOXY 6 THIOGUANOSINE 341
24918 1                   TRANSCRIPTION FACTOR DECOY//DECOY//NF KAPPA B DECOY 297
28042 1                   CROSS LINKED DNA DUPLEXES//OLIGONUCLEOTIDE 3 PHOSPHOROTHIOATES//OLIGONUCLEOTIDE MODIFICATION 215
36765 1                   PROGRAM BIOCHEM CHEM//2 SELENOURIDINE TRIPHOSPHATE//3 5 O DIACETYL 5 AMINOMETHYL 2 DEOXYURIDINE 74

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS journal 498824 7% 24% 1137
2 OLIGONUCLEOTIDES authKW 392087 5% 28% 775
3 PEPTIDE NUCLEIC ACID authKW 312787 2% 56% 311
4 ANTISENSE authKW 155040 3% 20% 428
5 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT journal 154820 1% 48% 179
6 NUCLE ACID address 139486 1% 54% 145
7 TRIPLEX authKW 118043 1% 60% 109
8 PNA authKW 109238 1% 40% 153
9 NUCLEIC ACIDS RESEARCH journal 87873 8% 4% 1399
10 PHOSPHOROTHIOATE authKW 83085 1% 40% 117

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Chemistry, Organic 50797 26% 1% 4329
2 Biochemistry & Molecular Biology 48271 45% 0% 7651
3 Chemistry, Multidisciplinary 11525 19% 0% 3244
4 Chemistry, Medicinal 6650 7% 0% 1114
5 Biochemical Research Methods 3232 6% 0% 937
6 Biophysics 2344 5% 0% 907
7 Biotechnology & Applied Microbiology 763 4% 0% 744
8 Medicine, Research & Experimental 426 3% 0% 528
9 Pharmacology & Pharmacy 140 5% 0% 776
10 Chemistry, Analytical 51 2% 0% 408

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NUCLE ACID 139486 1% 54% 145
2 NUCL ACID 82066 0% 62% 74
3 SYNTHET BIOORGAN CHEM 53989 0% 100% 30
4 BIOMOL RECOGNIT 44680 0% 47% 53
5 NEWCAT 35840 0% 59% 34
6 NOVOSIBIRSK BIOORGAN CHEM 35197 0% 28% 71
7 GILEAD IOCB 34565 0% 62% 31
8 BIOORGAN CHEM 32850 2% 5% 371
9 BIOORGAN CHEM CHEM BIOL 31949 0% 44% 40
10 UMR 5625 18611 0% 28% 37

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 498824 7% 24% 1137
2 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT 154820 1% 48% 179
3 NUCLEIC ACIDS RESEARCH 87873 8% 4% 1399
4 BIOORGANICHESKAYA KHIMIYA 57887 2% 10% 325
5 ANTISENSE RESEARCH AND DEVELOPMENT 56760 0% 67% 47
6 NUCLEOSIDES & NUCLEOTIDES 45526 1% 20% 130
7 BIOCONJUGATE CHEMISTRY 28290 2% 6% 282
8 TETRAHEDRON LETTERS 17767 5% 1% 878
9 OLIGONUCLEOTIDES 17318 0% 19% 51
10 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS 15736 1% 5% 167

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 OLIGONUCLEOTIDES 392087 5% 28% 775 Search OLIGONUCLEOTIDES Search OLIGONUCLEOTIDES
2 PEPTIDE NUCLEIC ACID 312787 2% 56% 311 Search PEPTIDE+NUCLEIC+ACID Search PEPTIDE+NUCLEIC+ACID
3 ANTISENSE 155040 3% 20% 428 Search ANTISENSE Search ANTISENSE
4 TRIPLEX 118043 1% 60% 109 Search TRIPLEX Search TRIPLEX
5 PNA 109238 1% 40% 153 Search PNA Search PNA
6 PHOSPHOROTHIOATE 83085 1% 40% 117 Search PHOSPHOROTHIOATE Search PHOSPHOROTHIOATE
7 ANTIGENE 82401 0% 78% 59 Search ANTIGENE Search ANTIGENE
8 ANTISENSE OLIGONUCLEOTIDES 81312 2% 17% 268 Search ANTISENSE+OLIGONUCLEOTIDES Search ANTISENSE+OLIGONUCLEOTIDES
9 TRIPLEX DNA 70673 0% 62% 63 Search TRIPLEX+DNA Search TRIPLEX+DNA
10 MODIFIED OLIGONUCLEOTIDES 62599 0% 55% 63 Search MODIFIED+OLIGONUCLEOTIDES Search MODIFIED+OLIGONUCLEOTIDES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BEAUCAGE, SL , IYER, RP , (1992) ADVANCES IN THE SYNTHESIS OF OLIGONUCLEOTIDES BY THE PHOSPHORAMIDITE APPROACH.TETRAHEDRON. VOL. 48. ISSUE 12. P. 2223-2311 389 91% 497
2 ROBLES, J , GRANDAS, A , PEDROSO, E , LUQUE, FJ , ERITJA, R , OROZCO, M , (2002) NUCLEIC ACID TRIPLE HELICES: STABILITY EFFECTS OF NUCLEOBASE MODIFICATIONS.CURRENT ORGANIC CHEMISTRY. VOL. 6. ISSUE 14. P. 1333 -1368 311 84% 33
3 UHLMANN, E , PEYMAN, A , (1990) ANTISENSE OLIGONUCLEOTIDES - A NEW THERAPEUTIC PRINCIPLE.CHEMICAL REVIEWS. VOL. 90. ISSUE 4. P. 543 -584 215 67% 1307
4 ABRAMOVA, TV , SILNIKOV, VN , (2011) SYNTHESIS AND PROPERTIES OF CARBOHYDRATE - PHOSPHATE BACKBONE-MODIFIED OLIGONUCLEOTIDE ANALOGUES AND NUCLEIC ACID MIMETICS.RUSSIAN CHEMICAL REVIEWS. VOL. 80. ISSUE 5. P. 429 -452 197 83% 4
5 DUCA, M , VEKHOFF, P , OUSSEDIK, K , HALBY, L , ARIMONDO, PB , (2008) THE TRIPLE HELIX: 50 YEARS LATER, THE OUTCOME.NUCLEIC ACIDS RESEARCH. VOL. 36. ISSUE 16. P. 5123 -5138 163 79% 169
6 BEAUCAGE, SL , IYER, RP , (1993) THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES BY THE PHOSPHORAMIDITE APPROACH AND THEIR APPLICATIONS.TETRAHEDRON. VOL. 49. ISSUE 28. P. 6123 -6194 320 62% 293
7 GHOSH, PK , KUMAR, P , GUPTA, KC , (2000) RECENT ADVANCES IN SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES.JOURNAL OF THE INDIAN CHEMICAL SOCIETY. VOL. 77. ISSUE 3. P. 109 -132 261 81% 10
8 PRASEUTH, D , GUIEYSSE, AL , HELENE, C , (1999) TRIPLE HELIX FORMATION AND THE ANTIGENE STRATEGY FOR SEQUENCE-SPECIFIC CONTROL OF GENE EXPRESSION.BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION. VOL. 1489. ISSUE 1. P. 181 -206 188 85% 233
9 HARI, Y , OBIKA, S , IMANISHI, T , (2012) TOWARDS THE SEQUENCE-SELECTIVE RECOGNITION OF DOUBLE-STRANDED DNA CONTAINING PYRIMIDINE-PURINE INTERRUPTIONS BY TRIPLEX-FORMING OLIGONUCLEOTIDES.EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. VOL. . ISSUE 15. P. 2875-2887 133 100% 17
10 TEO, YN , KOOL, ET , (2012) DNA-MULTICHROMOPHORE SYSTEMS.CHEMICAL REVIEWS. VOL. 112. ISSUE 7. P. 4221-4245 173 54% 132

Classes with closest relation at Level 2


Rank Class id link
1 2728 G QUADRUPLEX//QUADRUPLEX//G QUADRUPLEX DNA
2 793 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//NUCLEOSIDES//CARBOCYCLIC NUCLEOSIDES
3 1185 RIBOZYME//RNASE P//CATALYTIC RNA
4 1714 MOLECULAR BEACON//MUTATION DETECTION//SEQUENCING BY HYBRIDIZATION
5 1995 DNA ORIGAMI//DNA NANOTECHNOLOGY//DNA NANOSTRUCTURES
6 740 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS//SINGLE MOLECULE FORCE SPECTROSCOPY//Z DNA
7 3408 ADENYLATE KINASE//PHOSPHOGLYCERATE KINASE//CHIM STRUCT MACROMOL
8 4012 N PHOSPHORYL AMINO ACID//BIOORGAN PHOSPHORUS CHEM//PHOSPHOPEPTIDE SYNTHESIS
9 1989 ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES//ORIGIN OF LIFE//GENETIC CODE
10 3929 TRIVALINE//POLYNUCLEOTIDE ANALOGUE//ADENOSINE IMMOBILIZED SILICA

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