Class information for:
Level 2: PEPT1//ORGANIC CATION TRANSPORTER//OATP1B1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1155 9490 40.1 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
230 3       P GLYCOPROTEIN//FMO3//TRIMETHYLAMINURIA 49374
1155 2             PEPT1//ORGANIC CATION TRANSPORTER//OATP1B1 9490
1901 1                   BIOPHARMACEUTICS CLASSIFICATION SYSTEM//ORAL ABSORPTION//CACO 2 2436
3077 1                   ORGANIC CATION TRANSPORTER//ORGANIC ANION TRANSPORTER//ORGANIC CATION TRANSPORT 2072
5456 1                   OATP1B1//SLCO1B1//OATP 1621
7903 1                   PEPT1//PEPT2//PEPTIDE TRANSPORTER 1315
7913 1                   MICRODIALYSIS//MICRODIALYSIS SAMPLING//RELATIVE RECOVERY 1314
20325 1                   LOGBB//BLOOD BRAIN PARTITIONING//PAMPA BBB 466
30937 1                   INNER BLOOD RETINAL BARRIER//PROTON COUPLED ORGANIC CATION ANTIPORTER//RETINAL CAPILLARY ENDOTHELIAL CELLS 161
34850 1                   CEFADROXIL INTESTINAL ABSORPTION//CAS 50370 12 2//QUINOLONE ANTIMICROBIAL AGENT 105

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEPT1 authKW 333387 1% 76% 137
2 ORGANIC CATION TRANSPORTER authKW 248951 2% 54% 143
3 OATP1B1 authKW 235620 1% 81% 91
4 MOL PHARMACOKINET address 214110 1% 57% 116
5 ORGANIC ANION TRANSPORTER authKW 205732 1% 51% 126
6 SLCO1B1 authKW 171324 1% 73% 73
7 PEPTIDE TRANSPORTER authKW 165504 1% 59% 87
8 CACO 2 authKW 161719 3% 20% 257
9 BIOPHARMACEUTICS CLASSIFICATION SYSTEM authKW 161119 1% 73% 69
10 PEPT2 authKW 159456 1% 90% 55

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pharmacology & Pharmacy 109291 62% 1% 5867
2 Chemistry, Medicinal 7796 9% 0% 867
3 Physiology 3024 7% 0% 672
4 Chemistry, Multidisciplinary 2536 13% 0% 1265
5 Toxicology 1044 4% 0% 372
6 Medicine, Research & Experimental 886 5% 0% 455
7 Biochemistry & Molecular Biology 510 11% 0% 1040
8 Chemistry, Analytical 471 5% 0% 436
9 Biochemical Research Methods 359 3% 0% 289
10 Urology & Nephrology 337 3% 0% 239

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL PHARMACOKINET 214110 1% 57% 116
2 PHARMSAKYO KU 77207 0% 65% 37
3 PROV PHARMACOKINET TRANSPORT 53658 0% 76% 22
4 SUGIYAMA 47817 0% 55% 27
5 KYOTO UNIV HOSP 46969 1% 28% 53
6 RIKEN INNOVAT 46228 0% 55% 26
7 ABT VEGETAT PHYSIOL PATHOPHYSIOL 40482 0% 55% 23
8 PHARMACEUT 37524 6% 2% 592
9 UPJOHN CLIN PHARMACOL 35162 0% 58% 19
10 MOL NUTR UNIT 34529 1% 20% 55

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACEUTICAL RESEARCH 118616 6% 7% 544
2 DRUG METABOLISM AND DISPOSITION 90623 5% 6% 461
3 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 69826 3% 8% 277
4 MOLECULAR PHARMACEUTICS 57552 3% 8% 238
5 JOURNAL OF PHARMACEUTICAL SCIENCES 56869 5% 4% 447
6 DRUG METABOLISM AND PHARMACOKINETICS 35172 1% 12% 89
7 AAPS JOURNAL 29422 1% 9% 102
8 DISSOLUTION TECHNOLOGIES 28936 0% 21% 43
9 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 26034 4% 2% 417
10 BIOPHARMACEUTICS & DRUG DISPOSITION 14912 1% 5% 95

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PEPT1 333387 1% 76% 137 Search PEPT1 Search PEPT1
2 ORGANIC CATION TRANSPORTER 248951 2% 54% 143 Search ORGANIC+CATION+TRANSPORTER Search ORGANIC+CATION+TRANSPORTER
3 OATP1B1 235620 1% 81% 91 Search OATP1B1 Search OATP1B1
4 ORGANIC ANION TRANSPORTER 205732 1% 51% 126 Search ORGANIC+ANION+TRANSPORTER Search ORGANIC+ANION+TRANSPORTER
5 SLCO1B1 171324 1% 73% 73 Search SLCO1B1 Search SLCO1B1
6 PEPTIDE TRANSPORTER 165504 1% 59% 87 Search PEPTIDE+TRANSPORTER Search PEPTIDE+TRANSPORTER
7 CACO 2 161719 3% 20% 257 Search CACO+2 Search CACO+2
8 BIOPHARMACEUTICS CLASSIFICATION SYSTEM 161119 1% 73% 69 Search BIOPHARMACEUTICS+CLASSIFICATION+SYSTEM Search BIOPHARMACEUTICS+CLASSIFICATION+SYSTEM
9 PEPT2 159456 1% 90% 55 Search PEPT2 Search PEPT2
10 MICRODIALYSIS 159305 6% 8% 594 Search MICRODIALYSIS Search MICRODIALYSIS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ROTH, M , OBAIDAT, A , HAGENBUCH, B , (2012) OATPS, OATS AND OCTS: THE ORGANIC ANION AND CATION TRANSPORTERS OF THE SLCO AND SLC22A GENE SUPERFAMILIES.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 165. ISSUE 5. P. 1260 -1287 236 81% 134
2 WRIGHT, SH , DANTZLER, WH , (2004) MOLECULAR AND CELLULAR PHYSIOLOGY OF RENAL ORGANIC CATION AND ANION TRANSPORT.PHYSIOLOGICAL REVIEWS. VOL. 84. ISSUE 3. P. 987-1049 352 69% 234
3 BRANDSCH, M , KNUTTER, I , BOSSE-DOENECKE, E , (2008) PHARMACEUTICAL AND PHARMACOLOGICAL IMPORTANCE OF PEPTIDE TRANSPORTERS.JOURNAL OF PHARMACY AND PHARMACOLOGY. VOL. 60. ISSUE 5. P. 543-585 228 89% 95
4 BURCKHARDT, G , (2012) DRUG TRANSPORT BY ORGANIC ANION TRANSPORTERS (OATS).PHARMACOLOGY & THERAPEUTICS. VOL. 136. ISSUE 1. P. 106 -130 195 84% 78
5 VANWERT, AL , GIONFRIDDO, MR , SWEET, DH , (2010) ORGANIC ANION TRANSPORTERS: DISCOVERY, PHARMACOLOGY, REGULATION AND ROLES IN PATHOPHYSIOLOGY.BIOPHARMACEUTICS & DRUG DISPOSITION. VOL. 31. ISSUE 1. P. 1-71 205 82% 86
6 PELIS, RM , WRIGHT, SH , (2011) RENAL TRANSPORT OF ORGANIC ANIONS AND CATIONS.COMPREHENSIVE PHYSIOLOGY. VOL. 1. ISSUE 4. P. 1795-1835 282 63% 11
7 NIEMI, M , PASANEN, MK , NEUVONEN, PJ , (2011) ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B1: A GENETICALLY POLYMORPHIC TRANSPORTER OF MAJOR IMPORTANCE FOR HEPATIC DRUG UPTAKE.PHARMACOLOGICAL REVIEWS. VOL. 63. ISSUE 1. P. 157-181 153 70% 234
8 KLAASSEN, CD , ALEKSUNES, LM , (2010) XENOBIOTIC, BILE ACID, AND CHOLESTEROL TRANSPORTERS: FUNCTION AND REGULATION.PHARMACOLOGICAL REVIEWS. VOL. 62. ISSUE 1. P. 1 -96 355 29% 293
9 GIACOMINI, KM , HUANG, SM , TWEEDIE, DJ , BENET, LZ , BROUWER, KLR , CHU, XY , DAHLIN, A , EVERS, R , FISCHER, V , HILLGREN, KM , ET AL (2010) MEMBRANE TRANSPORTERS IN DRUG DEVELOPMENT.NATURE REVIEWS DRUG DISCOVERY. VOL. 9. ISSUE 3. P. 215 -236 113 55% 1007
10 RIEDMAIER, AE , NIES, AT , SCHAEFFELER, E , SCHWAB, M , (2012) ORGANIC ANION TRANSPORTERS AND THEIR IMPLICATIONS IN PHARMACOTHERAPY.PHARMACOLOGICAL REVIEWS. VOL. 64. ISSUE 3. P. 421 -449 166 81% 27

Classes with closest relation at Level 2


Rank Class id link
1 747 P GLYCOPROTEIN//MULTIDRUG RESISTANCE//MDR1
2 1171 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM
3 2404 HUMMINGBIRDS//SGLT1//NA ATPASE
4 1694 MUCOADHESION//THIOMERS//ABSORPTION ENHANCER
5 1019 BILE ACIDS//FARNESOID X RECEPTOR//CHOLESTASIS
6 1787 NANOEMULSION//MICROEMULSION//POLYHIPE
7 2409 BLOOD BRAIN BARRIER//CEREBROLYSIN//TYR MIF 1
8 157 DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY//SOLID DISPERSION//INTERNATIONAL JOURNAL OF PHARMACEUTICS
9 2899 OCULAR DRUG DELIVERY//OPHTHALMIC DRUG DELIVERY//OCULAR DELIVERY
10 3716 CARBOXYLESTERASE//DRUG METAB BIOPHARMACEUT//CES2

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