CACTUS - Contrast Agent for CT and Ultrasound: manufacturing and characterization
Description (background and methods)
Initial phase of the project adressed the possibility to introduce Iodine-consisting particles in the polymer shell of gasholdning microbubbles.
The second phase of the project assessed the posibility to combine gas filled MBs, currently used as an ultrasound contrast agent, with gold nanoparticles that are used as a preclinical contrast agent for computer tomography (CT). Size destributioin, enchansement in sonographic and CT image were determined.
(Preliminary) results and publications
- Chen H, Larsson D, Zhao Y[A1] , Janerot-Sjöberg B, Colarieti-Tosti M, Grishenkov D[A2] Polymer Microbubbles as Dual Modal Contrast Agent for Ultrasound and Computed Tomography, In preparation.
Collaborations
- Division of Functional Imaging and Technology | Dept. of Clinical Science, Intervention and Technology (CLINTEC) | Karolinska Institutet
- Dept. of Clinical Physiology | Karolinska University Hospital | C1-88 Huddinge
Thesis projects
Hongjian Chen, Towards the Development of the Dual Modal Contrast Agent for Computed Tomography and Ultrasound diva-link
Contact person
Contributors
