Class information for:
Level 1: INSULIN GENE THERAPY//ENDOCRINOL METAB SECT 111//INSULIN STORAGE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
25097 291 41.9 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
297 3       DIABETES//ISLET TRANSPLANTATION//BETA CELL 41297
457 2             BETA CELL//INSULIN SECRETION//PANCREATIC ISLETS 16005
25097 1                   INSULIN GENE THERAPY//ENDOCRINOL METAB SECT 111//INSULIN STORAGE 291

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INSULIN GENE THERAPY authKW 419728 1% 100% 4
2 ENDOCRINOL METAB SECT 111 address 314796 1% 100% 3
3 INSULIN STORAGE authKW 279816 1% 67% 4
4 GLUCOSE TRANSPORTER TYPE 2 GLUT2 authKW 209864 1% 100% 2
5 HUMAN INSULIN GENE authKW 167887 1% 40% 4
6 PANCREATIC SUBSTITUTE authKW 167887 1% 40% 4
7 ADENOVIRUS E3 GENES authKW 104932 0% 100% 1
8 ARTIFICIAL BETA CELLS authKW 104932 0% 100% 1
9 BK 32 PROJECT TEAM NANOBIOMAT CELL BASED IMP address 104932 0% 100% 1
10 CELL MECHANISM REGULAT address 104932 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Transplantation 2099 18% 0% 52
2 Medicine, Research & Experimental 1412 26% 0% 77
3 Endocrinology & Metabolism 919 22% 0% 65
4 Biotechnology & Applied Microbiology 776 23% 0% 66
5 Genetics & Heredity 588 20% 0% 57
6 Cell & Tissue Engineering 307 3% 0% 9
7 Immunology 200 14% 0% 41
8 Surgery 170 15% 0% 43
9 Biochemistry & Molecular Biology 120 21% 0% 60
10 Biophysics 106 8% 0% 23

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ENDOCRINOL METAB SECT 111 314796 1% 100% 3
2 BK 32 PROJECT TEAM NANOBIOMAT CELL BASED IMP 104932 0% 100% 1
3 CELL MECHANISM REGULAT 104932 0% 100% 1
4 CLIN SCI H4 748 104932 0% 100% 1
5 CRANIO IAL MESENCHYMAL BIOL PROGRAMELI EDY 104932 0% 100% 1
6 DIABET RANGOS 5102 104932 0% 100% 1
7 EMORY ENGN LIVING TISSUES GTEC 104932 0% 100% 1
8 ENDOCRINOL DIABET LIPIDS INTERNAL MED 104932 0% 100% 1
9 ENDOCRINOL METAB LIPIDSATLANTA VA MED 104932 0% 100% 1
10 ENDOCRINOL METAB PEDIATUPMC 104932 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF GENE MEDICINE 9021 4% 1% 11
2 GENE THERAPY 6849 5% 0% 16
3 HUMAN GENE THERAPY 4518 4% 0% 12
4 DEUTSCHE ZEITSCHRIFT FUR PHILOSOPHIE 3388 2% 1% 5
5 CURRENT GENE THERAPY 3056 1% 1% 4
6 TRANSPLANTATION PROCEEDINGS 2495 11% 0% 31
7 JOURNAL OF MOLECULAR ENDOCRINOLOGY 2452 2% 0% 7
8 MOLECULAR THERAPY 2386 3% 0% 9
9 MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT 2302 1% 1% 2
10 CELL TRANSPLANTATION 1926 2% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 INSULIN GENE THERAPY 419728 1% 100% 4 Search INSULIN+GENE+THERAPY Search INSULIN+GENE+THERAPY
2 INSULIN STORAGE 279816 1% 67% 4 Search INSULIN+STORAGE Search INSULIN+STORAGE
3 GLUCOSE TRANSPORTER TYPE 2 GLUT2 209864 1% 100% 2 Search GLUCOSE+TRANSPORTER+TYPE+2+GLUT2 Search GLUCOSE+TRANSPORTER+TYPE+2+GLUT2
4 HUMAN INSULIN GENE 167887 1% 40% 4 Search HUMAN+INSULIN+GENE Search HUMAN+INSULIN+GENE
5 PANCREATIC SUBSTITUTE 167887 1% 40% 4 Search PANCREATIC+SUBSTITUTE Search PANCREATIC+SUBSTITUTE
6 ADENOVIRUS E3 GENES 104932 0% 100% 1 Search ADENOVIRUS+E3+GENES Search ADENOVIRUS+E3+GENES
7 ARTIFICIAL BETA CELLS 104932 0% 100% 1 Search ARTIFICIAL+BETA+CELLS Search ARTIFICIAL+BETA+CELLS
8 CHO CHINESE HAMSTER OVARY CELL LINE 104932 0% 100% 1 Search CHO+CHINESE+HAMSTER+OVARY+CELL+LINE Search CHO+CHINESE+HAMSTER+OVARY+CELL+LINE
9 CONCANAVALIN A GLYCOGEN 104932 0% 100% 1 Search CONCANAVALIN+A+GLYCOGEN Search CONCANAVALIN+A+GLYCOGEN
10 EMOTIONALISATION 104932 0% 100% 1 Search EMOTIONALISATION Search EMOTIONALISATION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 OLSON, DE , THULE, PM , (2008) GENE TRANSFER TO INDUCE INSULIN PRODUCTION FOR THE TREATMENT OF DIABETES MELLITUS.EXPERT OPINION ON DRUG DELIVERY. VOL. 5. ISSUE 9. P. 967-977 48 53% 3
2 SANLIOGLU, AD , ALTUNBAS, HA , BALCI, MK , GRIFFITH, TS , SANLIOGLU, S , (2012) INSULIN GENE THERAPY FROM DESIGN TO BETA CELL GENERATION.EXPERT REVIEWS IN MOLECULAR MEDICINE. VOL. 14. ISSUE . P. - 32 49% 2
3 OH, TK , LI, MZ , KIM, ST , (2006) GENE THERAPY FOR DIABETES MELLITUS IN RATS BY INTRAMUSCULAR INJECTION OF LENTIVIRUS CONTAINING INSULIN GENE.DIABETES RESEARCH AND CLINICAL PRACTICE. VOL. 71. ISSUE 3. P. 233 -240 20 74% 15
4 OLSON, DE , PAVEGLIO, SA , HUEY, PU , PORTER, MH , THULE, PM , (2003) GLUCOSE-RESPONSIVE HEPATIC INSULIN GENE THERAPY OF SPONTANEOUSLY DIABETIC BB/WOR RATS.HUMAN GENE THERAPY. VOL. 14. ISSUE 15. P. 1401-1413 24 60% 31
5 PARK, YM , WOO, SA , LEE, GT , KO, JY , LEE, Y , ZHAO, ZS , KIM, HJ , AHN, CW , CHA, BS , KIM, KS , ET AL (2005) SAFETY AND EFFICACY OF ADENO-ASSOCIATED VIRAL VECTOR-MEDIATED INSULIN GENE TRANSFER VIA PORTAL VEIN TO THE LIVERS OF STREPTOZOTOCIN-INDUCED DIABETIC SPRAGUE-DAWLEY RATS.JOURNAL OF GENE MEDICINE. VOL. 7. ISSUE 5. P. 621-629 21 57% 12
6 NETT, PC , SOLLINGER, HW , ALAM, T , (2003) HEPATIC INSULIN GENE THERAPY IN INSULIN-DEPENDENT DIABETES MELLITUS.AMERICAN JOURNAL OF TRANSPLANTATION. VOL. 3. ISSUE 10. P. 1197-1203 36 35% 9
7 YASUTOMI, K , ITOKAWA, Y , ASADA, H , KISHIDA, T , CUI, FD , OHASHI, S , GOJO, S , UEDA, Y , KUBO, T , YAMAGISHI, H , ET AL (2003) INTRAVASCULAR INSULIN GENE DELIVERY AS POTENTIAL THERAPEUTIC INTERVENTION IN DIABETES MELLITUS.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. VOL. 310. ISSUE 3. P. 897-903 20 63% 13
8 COTUGNO, G , POLLOCK, R , FORMISANO, P , LINHER, K , BEGUINOT, F , AURICCHIO, A , (2004) PHARMACOLOGICAL REGULATION OF THE INSULIN RECEPTOR SIGNALING PATHWAY MIMICS INSULIN ACTION IN CELLS TRANSDUCED WITH VIRAL VECTORS.HUMAN GENE THERAPY. VOL. 15. ISSUE 11. P. 1101-1108 20 61% 1
9 LIU, YY , JIA, W , WANKE, IE , MURUVE, DA , XIAO, HP , WONG, NCW , (2013) GLUCOSE REGULATES SECRETION OF EXOGENOUSLY EXPRESSED INSULIN FROM HEPG2 CELLS IN VITRO AND IN A MOUSE MODEL OF DIABETES MELLITUS IN VIVO.JOURNAL OF MOLECULAR ENDOCRINOLOGY. VOL. 50. ISSUE 3. P. 337-346 17 55% 0
10 HSU, PYJ , KOTIN, RM , YANG, YW , (2008) GLUCOSE- AND METABOLICALLY REGULATED HEPATIC INSULIN GENE THERAPY FOR DIABETES.PHARMACEUTICAL RESEARCH. VOL. 25. ISSUE 6. P. 1460-1468 19 53% 8

Classes with closest relation at Level 1


Rank Class id link
1 10494 GLUCOKINASE//GLUCOKINASE ACTIVATOR//GLUCOKINASE REGULATORY PROTEIN
2 585 INSULIN PRODUCING CELLS//PDX1//PDX 1
3 6997 MOL MED GENE THER Y UNIT//ADENOVIRUS//HELPER DEPENDENT ADENOVIRAL VECTOR
4 19466 E2A GENE//RAT INSULIN II GENE//UNITE DIABETOL CLIN
5 2440 FURIN//CARBOXYPEPTIDASE E//PROHORMONE CONVERTASE
6 20705 PROINSULIN//INTACT PROINSULIN//TRUE INSULIN
7 7605 PANDER//FAM3B//BIOCHEM IMMUNE SYST
8 382 ISLET TRANSPLANTATION//ISLET ISOLATION//CLIN ISLET TRANSPLANT PROGRAM
9 24507 C PEPTIDE//PROINSULIN C PEPTIDE//SECT CLIN PHYSIOL
10 12692 CHREBP//CARBOHYDRATE RESPONSE ELEMENT BINDING PROTEIN CHREBP//CARBOHYDRATE RESPONSE ELEMENT BINDING PROTEIN

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