Class information for:
Level 1: HERPES SIMPLEX VIRUS VECTOR//W ROXBURY VA HOSP//HELPER VIRUS FREE PACKAGING

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
25514 279 44.7 83%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
220 3       CYTOMEGALOVIRUS//VIROLOGY//JOURNAL OF VIROLOGY 50388
545 2             VIROLOGY//JOURNAL OF VIROLOGY//PSEUDORABIES VIRUS 14689
25514 1                   HERPES SIMPLEX VIRUS VECTOR//W ROXBURY VA HOSP//HELPER VIRUS FREE PACKAGING 279

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HERPES SIMPLEX VIRUS VECTOR authKW 1519597 7% 73% 19
2 W ROXBURY VA HOSP address 1474628 6% 84% 16
3 HELPER VIRUS FREE PACKAGING authKW 437782 1% 100% 4
4 HSV AMPLICON authKW 383052 3% 50% 7
5 HSV 1 AMPLICON VECTORS authKW 250157 1% 57% 4
6 GLUTAMATERGIC NEURON SPECIFIC EXPRESSION authKW 246251 1% 75% 3
7 NEUROFILAMENT PROMOTER authKW 246251 1% 75% 3
8 HERPES SIMPLEX VIRUS TYPE 1 VECTORS authKW 218891 1% 100% 2
9 HSV 1 AMPLICON VIRAL VECTOR authKW 218891 1% 100% 2
10 HSV 1 BASED AMPLICONS authKW 218891 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biotechnology & Applied Microbiology 1432 31% 0% 86
2 Medicine, Research & Experimental 1210 25% 0% 70
3 Neurosciences 1170 38% 0% 107
4 Genetics & Heredity 1021 26% 0% 72
5 Virology 945 14% 0% 40
6 Biochemical Research Methods 232 10% 0% 29
7 Biochemistry & Molecular Biology 107 20% 0% 56
8 CYTOLOGY & HISTOLOGY 13 0% 0% 1
9 Cell Biology 11 5% 0% 15
10 Behavioral Sciences 2 1% 0% 3

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 W ROXBURY VA HOSP 1474628 6% 84% 16
2 CELLULAR BIOL NEUROSCI PROF EDUARDO DE ROB 145926 1% 67% 2
3 GILBERT 113998 2% 21% 5
4 MOL NEUROONCOL S 113998 2% 21% 5
5 BIOL MOL CELLULEDIFFERENT CELL CYCLE GRPU 109445 0% 100% 1
6 BNBCB 109445 0% 100% 1
7 BRAIN FUNCT GENOMJOINT NEUROPATHOGEN 109445 0% 100% 1
8 CENT PREVENT TREATMENT TUMOR 109445 0% 100% 1
9 CMCG 109445 0% 100% 1
10 CNR INESE MINIST EDUC 109445 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN GENE THERAPY 15878 8% 1% 22
2 CURRENT GENE THERAPY 9772 3% 1% 7
3 MOLECULAR THERAPY 7892 6% 0% 16
4 GENE THERAPY 7145 6% 0% 16
5 MOLECULAR BRAIN RESEARCH 1955 3% 0% 9
6 JOURNAL OF VIROLOGICAL METHODS 1258 3% 0% 9
7 JOURNAL OF GENE MEDICINE 1239 1% 0% 4
8 BIOTECHNIQUES 1144 3% 0% 8
9 JOURNAL OF NEUROSCIENCE METHODS 940 3% 0% 8
10 BRAIN RESEARCH 903 7% 0% 20

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HERPES SIMPLEX VIRUS VECTOR 1519597 7% 73% 19 Search HERPES+SIMPLEX+VIRUS+VECTOR Search HERPES+SIMPLEX+VIRUS+VECTOR
2 HELPER VIRUS FREE PACKAGING 437782 1% 100% 4 Search HELPER+VIRUS+FREE+PACKAGING Search HELPER+VIRUS+FREE+PACKAGING
3 HSV AMPLICON 383052 3% 50% 7 Search HSV+AMPLICON Search HSV+AMPLICON
4 HSV 1 AMPLICON VECTORS 250157 1% 57% 4 Search HSV+1+AMPLICON+VECTORS Search HSV+1+AMPLICON+VECTORS
5 GLUTAMATERGIC NEURON SPECIFIC EXPRESSION 246251 1% 75% 3 Search GLUTAMATERGIC+NEURON+SPECIFIC+EXPRESSION Search GLUTAMATERGIC+NEURON+SPECIFIC+EXPRESSION
6 NEUROFILAMENT PROMOTER 246251 1% 75% 3 Search NEUROFILAMENT+PROMOTER Search NEUROFILAMENT+PROMOTER
7 HERPES SIMPLEX VIRUS TYPE 1 VECTORS 218891 1% 100% 2 Search HERPES+SIMPLEX+VIRUS+TYPE+1+VECTORS Search HERPES+SIMPLEX+VIRUS+TYPE+1+VECTORS
8 HSV 1 AMPLICON VIRAL VECTOR 218891 1% 100% 2 Search HSV+1+AMPLICON+VIRAL+VECTOR Search HSV+1+AMPLICON+VIRAL+VECTOR
9 HSV 1 BASED AMPLICONS 218891 1% 100% 2 Search HSV+1+BASED+AMPLICONS Search HSV+1+BASED+AMPLICONS
10 NEUROFILAMENT HEAVY GENE PROMOTER 218891 1% 100% 2 Search NEUROFILAMENT+HEAVY+GENE+PROMOTER Search NEUROFILAMENT+HEAVY+GENE+PROMOTER

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 CUCHET, D , POTEL, C , THOMAS, J , EPSTEIN, AL , (2007) HSV-1 AMPLICON VECTORS: A PROMISING AND VERSATILE TOOL FOR GENE DELIVERY.EXPERT OPINION ON BIOLOGICAL THERAPY. VOL. 7. ISSUE 7. P. 975-995 70 45% 23
2 EPSTEIN, AL , (2009) HSV-1-DERIVED AMPLICON VECTORS: RECENT TECHNOLOGICAL IMPROVEMENTS AND REMAINING DIFFICULTIES - A REVIEW.MEMORIAS DO INSTITUTO OSWALDO CRUZ. VOL. 104. ISSUE 3. P. 399 -410 43 52% 14
3 EPSTEIN, AL , (2005) HSV-1-BASED AMPLICON VECTORS: DESIGN AND APPLICATIONS.GENE THERAPY. VOL. 12. ISSUE . P. S154-S158 28 70% 18
4 DE SILVA, S , BOWERS, WJ , (2009) HERPES VIRUS AMPLICON VECTORS.VIRUSES-BASEL. VOL. 1. ISSUE 3. P. 594-629 50 33% 9
5 CAO, HY , ZHANG, GR , GELLER, AI , (2011) ANTIBODY-MEDIATED TARGETED GENE TRANSFER OF HELPER VIRUS-FREE HSV-1 VECTORS TO RAT NEOCORTICAL NEURONS THAT CONTAIN EITHER NMDA RECEPTOR 2B OR 2A SUBUNITS.BRAIN RESEARCH. VOL. 1415. ISSUE . P. 127-135 27 48% 1
6 OEHMIG, A , FRAEFEL, C , BREAKEFIELD, XO , (2004) UPDATE ON HERPESVIRUS AMPLICON VECTORS.MOLECULAR THERAPY. VOL. 10. ISSUE 4. P. 630-643 45 32% 35
7 CUCHER, D , EPSTEIN, AL , (2008) FURTHER IMPROVEMENTS IN THE TECHNOLOGY OF HSV-1-BASED AMPLICON VECTORS - HJ FEDEROFF & WJ BOWERS: WO2007143681.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 18. ISSUE 7. P. 797-804 23 53% 0
8 JERUSALINSKY, D , BAEZ, MV , EPSTEIN, AL , (2012) HERPES SIMPLEX VIRUS TYPE 1-BASED AMPLICON VECTORS FOR FUNDAMENTAL RESEARCH IN NEUROSCIENCES AND GENE THERAPY OF NEUROLOGICAL DISEASES.JOURNAL OF PHYSIOLOGY-PARIS. VOL. 106. ISSUE 1-2. P. 2-11 33 32% 7
9 KASAI, K , SAEKI, Y , (2006) DNA-BASED METHODS TO PREPARE HELPER VIRUS-FREE HERPES AMPLICON VECTORS AND VERSATILE DESIGN OF AMPLICON VECTOR PLASMIDS.CURRENT GENE THERAPY. VOL. 6. ISSUE 3. P. 303 -314 26 48% 3
10 ZHANG, GR , ZHAO, H , CAO, HY , GELLER, AI , (2012) OVEREXPRESSION OF EITHER LYSINE-SPECIFIC DEMETHYLASE-1 OR CLOCK, BUT NOT CO-REST, IMPROVES LONG-TERM EXPRESSION FROM A MODIFIED NEUROFILAMENT PROMOTER, IN A HELPER VIRUS-FREE HSV-1 VECTOR SYSTEM.BRAIN RESEARCH. VOL. 1436. ISSUE . P. 157-167 23 46% 1

Classes with closest relation at Level 1


Rank Class id link
1 5791 MARJORIE B KOVLER VIRAL ONCOL S//ICP27//ICP0
2 6997 MOL MED GENE THER Y UNIT//ADENOVIRUS//HELPER DEPENDENT ADENOVIRAL VECTOR
3 13160 ICP8//UL9//ALKALINE NUCLEASE
4 1734 NEUROBIOL VACCINE DEV//HERPES SIMPLEX KERATITIS//LATENCY ASSOCIATED TRANSCRIPT
5 24340 HUMAN ARTIFICIAL CHROMOSOME//REGENERAT MED BIOFUNCT//CHROMOSOME ENGN
6 3831 GDNF//GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR//NEURTURIN
7 1181 ONCOLYTIC VIRUS//ONCOLYTIC ADENOVIRUS//VIROTHERAPY
8 1257 ADENO ASSOCIATED VIRUS//AAV//POWELL GENE THER Y
9 8740 CRE RECOMBINASE//TET SYSTEM//RTTA
10 9988 BCL 2//ROBERT S DOW NEUROBIOL S//EOSINOPHILIC NEURON

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