Class information for:
Level 1: EGF RECEPTOR//COMPUTER PROGRAM FOR MACINTOSHTMII//DIMERIZATION ARM

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5087 1675 44.4 80%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
1648 2             EPIDERMAL GROWTH FACTOR//HB EGF//TRANSFORMING GROWTH FACTOR ALPHA 6893
5087 1                   EGF RECEPTOR//COMPUTER PROGRAM FOR MACINTOSHTMII//DIMERIZATION ARM 1675

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EGF RECEPTOR authKW 94188 4% 7% 70
2 COMPUTER PROGRAM FOR MACINTOSHTMII authKW 36457 0% 100% 2
3 DIMERIZATION ARM authKW 36457 0% 100% 2
4 MED HEMATOL ONCOL BIOL CHEM address 36457 0% 100% 2
5 TKP PHOTON address 36457 0% 100% 2
6 TYROSINE KINASE INHIBITOR PD153035 authKW 36457 0% 100% 2
7 IMMUNOGENE authKW 36453 0% 50% 4
8 TOXICOPATHOL address 26240 0% 24% 6
9 ERBB PROTEINS authKW 24303 0% 67% 2
10 LIGAND INDUCED DIMERIZATION authKW 24303 0% 67% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 9177 38% 0% 640
2 Biochemistry & Molecular Biology 7816 56% 0% 942
3 CYTOLOGY & HISTOLOGY 1847 2% 0% 28
4 Biophysics 1362 11% 0% 188
5 Oncology 467 11% 0% 178
6 Physiology 201 5% 0% 80
7 Biology 132 3% 0% 54
8 Biochemical Research Methods 63 3% 0% 51
9 Mathematical & Computational Biology 43 1% 0% 21
10 Endocrinology & Metabolism 14 2% 0% 41

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MED HEMATOL ONCOL BIOL CHEM 36457 0% 100% 2
2 TKP PHOTON 36457 0% 100% 2
3 TOXICOPATHOL 26240 0% 24% 6
4 373 PLANTATION ST 18228 0% 100% 1
5 ANAT HISTOL EMBYOL 18228 0% 100% 1
6 BIOPHYS BIOPHYS CHEM HHMI 18228 0% 100% 1
7 BURGESS STRUCT BIOL 18228 0% 100% 1
8 CALIF QUANITAT BIOSCI 18228 0% 100% 1
9 CANC CANC CELL BIOL PROGRAM 18228 0% 100% 1
10 CANCER TREATMENT 18228 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF BIOLOGICAL CHEMISTRY 7271 15% 0% 249
2 JOURNAL OF CELLULAR PHYSIOLOGY 5413 3% 1% 55
3 EXPERIMENTAL CELL RESEARCH 3655 3% 0% 51
4 JOURNAL OF SUPRAMOLECULAR STRUCTURE AND CELLULAR BIOCHEMISTRY 2999 0% 4% 4
5 GROWTH FACTORS 2756 1% 1% 11
6 CELL REGULATION 2414 0% 3% 5
7 JOURNAL OF CELL BIOLOGY 1954 3% 0% 42
8 JOURNAL OF SUPRAMOLECULAR STRUCTURE 1858 0% 3% 3
9 BIOCHEMISTRY 1572 4% 0% 70
10 TSITOLOGIYA 1489 1% 1% 14

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 EGF RECEPTOR 94188 4% 7% 70 Search EGF+RECEPTOR Search EGF+RECEPTOR
2 COMPUTER PROGRAM FOR MACINTOSHTMII 36457 0% 100% 2 Search COMPUTER+PROGRAM+FOR+MACINTOSHTMII Search COMPUTER+PROGRAM+FOR+MACINTOSHTMII
3 DIMERIZATION ARM 36457 0% 100% 2 Search DIMERIZATION+ARM Search DIMERIZATION+ARM
4 TYROSINE KINASE INHIBITOR PD153035 36457 0% 100% 2 Search TYROSINE+KINASE+INHIBITOR+PD153035 Search TYROSINE+KINASE+INHIBITOR+PD153035
5 IMMUNOGENE 36453 0% 50% 4 Search IMMUNOGENE Search IMMUNOGENE
6 ERBB PROTEINS 24303 0% 67% 2 Search ERBB+PROTEINS Search ERBB+PROTEINS
7 LIGAND INDUCED DIMERIZATION 24303 0% 67% 2 Search LIGAND+INDUCED+DIMERIZATION Search LIGAND+INDUCED+DIMERIZATION
8 ERBB 22734 1% 7% 19 Search ERBB Search ERBB
9 EPIDERMAL GROWTH FACTOR RECEPTOR 21325 4% 2% 66 Search EPIDERMAL+GROWTH+FACTOR+RECEPTOR Search EPIDERMAL+GROWTH+FACTOR+RECEPTOR
10 EGFR 19305 5% 1% 76 Search EGFR Search EGFR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KOVACS, E , ZORN, JA , HUANG, YJ , BARROS, T , KURIYAN, J , (2015) A STRUCTURAL PERSPECTIVE ON THE REGULATION OF THE EPIDERMAL GROWTH FACTOR RECEPTOR.ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84. VOL. 84. ISSUE . P. 739 -764 70 52% 21
2 LEMMON, MA , (2009) LIGAND-INDUCED ERBB RECEPTOR DIMERIZATION.EXPERIMENTAL CELL RESEARCH. VOL. 315. ISSUE 4. P. 638-648 63 69% 99
3 LEMMON, MA , SCHLESSINGER, J , FERGUSON, KM , (2014) THE EGFR FAMILY: NOT SO PROTOTYPICAL RECEPTOR TYROSINE KINASES.COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. VOL. 6. ISSUE 4. P. - 60 57% 51
4 TYNAN, CJ , LO SCHIAVO, V , ZANETTI-DOMINGUES, L , NEEDHAM, SR , ROBERTS, SK , HIRSCH, M , ROLFE, DJ , KOROVESIS, D , CLARKE, DT , MARTIN-FERNANDEZ, ML , (2016) A TALE OF THE EPIDERMAL GROWTH FACTOR RECEPTOR: THE QUEST FOR STRUCTURAL RESOLUTION ON CELLS.METHODS. VOL. 95. ISSUE . P. 86 -93 57 66% 3
5 WALKER, F , ROTHACKER, J , HENDERSON, C , NICE, EC , CATIMEL, B , ZHANG, HH , SCOTT, AM , BAILEY, MF , ORCHARD, SG , ADAMS, TE , ET AL (2012) LIGAND BINDING INDUCES A CONFORMATIONAL CHANGE IN EPIDERMAL GROWTH FACTOR RECEPTOR DIMERS.GROWTH FACTORS. VOL. 30. ISSUE 6. P. 394-409 66 73% 6
6 ARKHIPOV, A , SHAN, YB , DAS, R , ENDRES, NF , EASTWOOD, MP , WEMMER, DE , KURIYAN, J , SHAW, DE , (2013) ARCHITECTURE AND MEMBRANE INTERACTIONS OF THE EGF RECEPTOR.CELL. VOL. 152. ISSUE 3. P. 557 -569 32 76% 163
7 BESSMAN, NJ , FREED, DM , LEMMON, MA , (2014) PUTTING TOGETHER STRUCTURES OF EPIDERMAL GROWTH FACTOR RECEPTORS.CURRENT OPINION IN STRUCTURAL BIOLOGY. VOL. 29. ISSUE . P. 95 -101 40 82% 14
8 KASZUBA, K , GRZYBEK, M , ORLOWSKI, A , DANNE, R , ROG, T , SIMONS, K , COSKUN, U , VATTULAINEN, I , (2015) N-GLYCOSYLATION AS DETERMINANT OF EPIDERMAL GROWTH FACTOR RECEPTOR CONFORMATION IN MEMBRANES.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. VOL. 112. ISSUE 14. P. 4334 -4339 37 66% 24
9 VALLEY, CC , ARNDT-JOVIN, DJ , KAREDLA, N , STEINKAMP, MP , CHIZHIK, AI , HLAVACEK, WS , WILSON, BS , LIDKE, KA , LIDKE, DS , (2015) ENHANCED DIMERIZATION DRIVES LIGAND-INDEPENDENT ACTIVITY OF MUTANT EPIDERMAL GROWTH FACTOR RECEPTOR IN LUNG CANCER.MOLECULAR BIOLOGY OF THE CELL. VOL. 26. ISSUE 22. P. 4087 -4099 51 59% 4
10 CARPENTER, G , (1987) RECEPTORS FOR EPIDERMAL GROWTH-FACTOR AND OTHER POLYPEPTIDE MITOGENS.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 56. ISSUE . P. 881-914 89 38% 1239

Classes with closest relation at Level 1


Rank Class id link
1 26980 CANC CAMPAIGN MED ONCOL UNIT//HTGF ALPHA//2ND SITE MUTATION
2 5515 TRANSFORMING GROWTH FACTOR ALPHA//TGF ALPHA//TGF ALPHA ASE
3 25822 V ERBB//HD3 CELLS//CANC SCI PK
4 30546 NUCLEAR EGFR//EGFR FAMILY RECEPTORS//P TYR
5 4433 NEUREGULIN//NEUREGULIN 1//ERBB4
6 29090 MIG 6//ACK1//RALT
7 26851 TSITOLOGIYA//CYTOLOGY & HISTOLOGY//CALCIUM PROTEIN KINASE C
8 13756 HB EGF//AMPHIREGULIN//HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR
9 4440 NIMOTUZUMAB//CETUXIMAB//EGFR
10 24850 TYRPHOSTIN//AG957//INOSTAMYCIN

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