Class information for:
Level 2: EPIDERMAL GROWTH FACTOR//HB EGF//TRANSFORMING GROWTH FACTOR ALPHA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1648 6893 39.9 76%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
1648 2             EPIDERMAL GROWTH FACTOR//HB EGF//TRANSFORMING GROWTH FACTOR ALPHA 6893
5087 1                   EGF RECEPTOR//COMPUTER PROGRAM FOR MACINTOSHTMII//DIMERIZATION ARM 1675
5515 1                   TRANSFORMING GROWTH FACTOR ALPHA//TGF ALPHA//TGF ALPHA ASE 1612
9806 1                   EPIDERMAL GROWTH FACTOR//PIGEON MILK//TRANSFORMING GROWTH FACTOR ALPHA 1118
11147 1                   RENAL HYPERTROPHY//URINARY IGF I//KIDNEY GROWTH 1004
13756 1                   HB EGF//AMPHIREGULIN//HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR 815
24202 1                   ASTROGLIAL CELL CULTURES//NEUROSTATIN//RUBAM QUIM AVANCADA CATALUNYA 320
26980 1                   CANC CAMPAIGN MED ONCOL UNIT//HTGF ALPHA//2ND SITE MUTATION 240
34628 1                   EGF POLYMORPHISM//EPIDERMAL GROWTH FACTOR POLYMORPHISMS//CRYPTOMPHALUS ASPERSA 109

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EPIDERMAL GROWTH FACTOR authKW 378325 7% 17% 499
2 HB EGF authKW 355570 2% 55% 147
3 TRANSFORMING GROWTH FACTOR ALPHA authKW 305434 3% 36% 192
4 EGF RECEPTOR authKW 149527 3% 19% 179
5 AMPHIREGULIN authKW 128295 1% 33% 87
6 TGF ALPHA authKW 123627 2% 23% 120
7 EGF authKW 108334 3% 12% 205
8 EPIDERMAL GROWTH FACTOR RECEPTOR authKW 86720 4% 7% 270
9 HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR authKW 76822 0% 54% 32
10 HEPARIN BINDING EGF LIKE GROWTH FACTOR authKW 75975 0% 59% 29

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Cell Biology 8191 19% 0% 1313
2 Biochemistry & Molecular Biology 6468 28% 0% 1948
3 Oncology 5758 17% 0% 1146
4 Endocrinology & Metabolism 2752 9% 0% 609
5 Physiology 2493 7% 0% 515
6 Gastroenterology & Hepatology 2040 6% 0% 411
7 Urology & Nephrology 1772 5% 0% 372
8 CYTOLOGY & HISTOLOGY 1493 1% 1% 52
9 Biophysics 1100 6% 0% 390
10 Pathology 385 3% 0% 195

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LIVER METASTASIS GRP 24105 0% 78% 7
2 PERINATAL PEDIAT SURG 18448 0% 83% 5
3 PROTEOMED PROM 14168 0% 80% 4
4 CELL GROWTH TUMOR REGULAT 13109 0% 23% 13
5 RUBAM QUIM AVANCADA CATALUNYA 9961 0% 75% 3
6 UNITAT PROLIFERACIO DIFERENCIACIO CELLULAR 9961 0% 75% 3
7 GF INGRASSIA HUMAN ANAT 8856 0% 100% 2
8 KARMANOS CANC BREAST CANC PROGRAM 8856 0% 100% 2
9 LOS ANGELES CTY HARBOR MED PERINATAL S 8856 0% 100% 2
10 MED HEMATOL ONCOL BIOL CHEM 8856 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GROWTH FACTORS 12759 1% 6% 48
2 JOURNAL OF CELLULAR PHYSIOLOGY 7015 2% 1% 128
3 ENDOCRINOLOGIA EXPERIMENTALIS 5914 0% 6% 21
4 JOURNAL OF BIOLOGICAL CHEMISTRY 4212 6% 0% 405
5 INTERFERON Y BIOTECNOLOGIA 3945 0% 18% 5
6 CANCER RESEARCH 3081 2% 0% 172
7 EXPERIMENTAL NEPHROLOGY 2865 0% 3% 19
8 AMERICAN JOURNAL OF PHYSIOLOGY 2724 2% 1% 128
9 JOURNAL OF CELLULAR BIOCHEMISTRY 2666 1% 1% 75
10 KIDNEY INTERNATIONAL 2373 1% 1% 91

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 EPIDERMAL GROWTH FACTOR 378325 7% 17% 499 Search EPIDERMAL+GROWTH+FACTOR Search EPIDERMAL+GROWTH+FACTOR
2 HB EGF 355570 2% 55% 147 Search HB+EGF Search HB+EGF
3 TRANSFORMING GROWTH FACTOR ALPHA 305434 3% 36% 192 Search TRANSFORMING+GROWTH+FACTOR+ALPHA Search TRANSFORMING+GROWTH+FACTOR+ALPHA
4 EGF RECEPTOR 149527 3% 19% 179 Search EGF+RECEPTOR Search EGF+RECEPTOR
5 AMPHIREGULIN 128295 1% 33% 87 Search AMPHIREGULIN Search AMPHIREGULIN
6 TGF ALPHA 123627 2% 23% 120 Search TGF+ALPHA Search TGF+ALPHA
7 EGF 108334 3% 12% 205 Search EGF Search EGF
8 EPIDERMAL GROWTH FACTOR RECEPTOR 86720 4% 7% 270 Search EPIDERMAL+GROWTH+FACTOR+RECEPTOR Search EPIDERMAL+GROWTH+FACTOR+RECEPTOR
9 HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR 76822 0% 54% 32 Search HEPARIN+BINDING+EPIDERMAL+GROWTH+FACTOR+LIKE+GROWTH+FACTOR Search HEPARIN+BINDING+EPIDERMAL+GROWTH+FACTOR+LIKE+GROWTH+FACTOR
10 HEPARIN BINDING EGF LIKE GROWTH FACTOR 75975 0% 59% 29 Search HEPARIN+BINDING+EGF+LIKE+GROWTH+FACTOR Search HEPARIN+BINDING+EGF+LIKE+GROWTH+FACTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LEE, DC , FENTON, SE , BERKOWITZ, EA , HISSONG, MA , (1995) TRANSFORMING GROWTH-FACTOR-ALPHA - EXPRESSION, REGULATION, AND BIOLOGICAL-ACTIVITIES.PHARMACOLOGICAL REVIEWS. VOL. 47. ISSUE 1. P. 51-85 194 63% 150
2 JORGENSEN, PE , (1997) URINARY EPIDERMAL GROWTH FACTOR.DANISH MEDICAL BULLETIN. VOL. 44. ISSUE 2. P. 111-124 127 74% 0
3 URIBE, JM , BARRETT, KE , (1997) NONMITOGENIC ACTIONS OF GROWTH FACTORS: AN INTEGRATED VIEW OF THEIR ROLE IN INTESTINAL PHYSIOLOGY AND PATHOPHYSIOLOGY.GASTROENTEROLOGY. VOL. 112. ISSUE 1. P. 255 -268 109 77% 55
4 MODJTAHEDI, H , DEAN, C , (1994) THE RECEPTOR FOR EGF AND ITS LIGANDS - EXPRESSION, PROGNOSTIC VALUE AND TARGET FOR THERAPY IN CANCER (REVIEW).INTERNATIONAL JOURNAL OF ONCOLOGY. VOL. 4. ISSUE 2. P. 277-296 156 55% 120
5 BARNARD, JA , BEAUCHAMP, RD , RUSSELL, WE , DUBOIS, RN , COFFEY, RJ , (1995) EPIDERMAL GROWTH FACTOR-RELATED PEPTIDES AND THEIR RELEVANCE TO GASTROINTESTINAL PATHOPHYSIOLOGY.GASTROENTEROLOGY. VOL. 108. ISSUE 2. P. 564-580 108 66% 255
6 GROENEN, LC , NICE, EC , BURGESS, AW , (1994) STRUCTURE-FUNCTION-RELATIONSHIPS FOR THE EGF/TGF-ALPHA FAMILY OF MITOGENS.GROWTH FACTORS. VOL. 11. ISSUE 4. P. 235-257 102 76% 179
7 LEMMON, MA , SCHLESSINGER, J , FERGUSON, KM , (2014) THE EGFR FAMILY: NOT SO PROTOTYPICAL RECEPTOR TYROSINE KINASES.COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. VOL. 6. ISSUE 4. P. - 63 59% 51
8 CARPENTER, G , (1987) RECEPTORS FOR EPIDERMAL GROWTH-FACTOR AND OTHER POLYPEPTIDE MITOGENS.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 56. ISSUE . P. 881-914 114 49% 1239
9 KOVACS, E , ZORN, JA , HUANG, YJ , BARROS, T , KURIYAN, J , (2015) A STRUCTURAL PERSPECTIVE ON THE REGULATION OF THE EPIDERMAL GROWTH FACTOR RECEPTOR.ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84. VOL. 84. ISSUE . P. 739 -764 71 53% 21
10 TYNAN, CJ , LO SCHIAVO, V , ZANETTI-DOMINGUES, L , NEEDHAM, SR , ROBERTS, SK , HIRSCH, M , ROLFE, DJ , KOROVESIS, D , CLARKE, DT , MARTIN-FERNANDEZ, ML , (2016) A TALE OF THE EPIDERMAL GROWTH FACTOR RECEPTOR: THE QUEST FOR STRUCTURAL RESOLUTION ON CELLS.METHODS. VOL. 95. ISSUE . P. 86 -93 58 67% 3

Classes with closest relation at Level 2


Rank Class id link
1 652 HER2//TRASTUZUMAB//HER 2 NEU
2 2228 C MYB//B MYB//SRC
3 3948 SPROUTY//LRIG1//MIG 6
4 3998 AMINO ACID LOAD//ADRENAL X ZONE MORPHOLOGY//RINBACIN
5 1452 CHRONIC MYELOID LEUKEMIA//IMATINIB//NILOTINIB
6 1844 TREFOIL FACTOR//CDX2//LGR5
7 1927 FGF21//FIBROBLAST GROWTH FACTOR//FIBROBLAST GROWTH FACTOR 21
8 1552 INSULIN RECEPTOR//INSULIN DEGRADING ENZYME//INOSITOL PHOSPHOGLYCAN
9 1072 TGF BETA//SMAD//ENDOGLIN
10 2491 MAMMARY GLAND//JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA//MAMMARY STEM CELLS

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