Class information for:
Level 1: HB EGF//AMPHIREGULIN//HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
13756 815 44.9 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
1648 2             EPIDERMAL GROWTH FACTOR//HB EGF//TRANSFORMING GROWTH FACTOR ALPHA 6893
13756 1                   HB EGF//AMPHIREGULIN//HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR 815

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HB EGF authKW 2575916 17% 51% 136
2 AMPHIREGULIN authKW 829009 9% 29% 76
3 HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR authKW 610210 4% 53% 31
4 HEPARIN BINDING EGF LIKE GROWTH FACTOR authKW 557367 3% 55% 27
5 BETACELLULIN authKW 391602 3% 37% 28
6 EGF FAMILY authKW 280975 2% 50% 15
7 EPIREGULIN authKW 269716 3% 30% 24
8 CRM197 authKW 257777 2% 40% 17
9 LIVER METASTASIS GRP address 203974 1% 78% 7
10 PERINATAL PEDIAT SURG address 156104 1% 83% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 1421 23% 0% 184
2 Oncology 1305 22% 0% 180
3 Biochemistry & Molecular Biology 762 28% 0% 230
4 Biophysics 260 7% 0% 61
5 Endocrinology & Metabolism 245 8% 0% 64
6 Developmental Biology 161 3% 0% 26
7 Dermatology 131 4% 0% 29
8 Gastroenterology & Hepatology 80 4% 0% 31
9 Physiology 74 4% 0% 35
10 Urology & Nephrology 56 3% 0% 26

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LIVER METASTASIS GRP 203974 1% 78% 7
2 PERINATAL PEDIAT SURG 156104 1% 83% 5
3 PROTEOMED PROM 119887 0% 80% 4
4 CELL GROWTH TUMOR REGULAT 111061 2% 23% 13
5 NEPHROLMED N S3223 74931 0% 100% 2
6 PEDIAT SURG PERINATAL 74931 0% 100% 2
7 PERINATAL NATIONWIDE CHILDRENS H 74931 0% 100% 2
8 CENT ADV MOL MED 57358 1% 22% 7
9 EHIME NIKON BIOIMAGING CORE 56195 0% 50% 3
10 PROTEO MED PROM 49952 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GROWTH FACTORS 18835 2% 3% 20
2 JOURNAL OF CELLULAR PHYSIOLOGY 1180 2% 0% 18
3 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 1114 6% 0% 46
4 TRANSGENICS 984 0% 3% 1
5 JOURNAL OF BIOLOGICAL CHEMISTRY 839 7% 0% 61
6 ANTICANCER RESEARCH 833 3% 0% 21
7 JOURNAL OF INVESTIGATIVE DERMATOLOGY 776 2% 0% 15
8 JOURNAL OF PEDIATRIC SURGERY 652 2% 0% 16
9 JOURNAL OF SURGICAL RESEARCH 585 2% 0% 13
10 INTERNATIONAL JOURNAL OF CANCER 573 2% 0% 18

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HB EGF 2575916 17% 51% 136 Search HB+EGF Search HB+EGF
2 AMPHIREGULIN 829009 9% 29% 76 Search AMPHIREGULIN Search AMPHIREGULIN
3 HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR 610210 4% 53% 31 Search HEPARIN+BINDING+EPIDERMAL+GROWTH+FACTOR+LIKE+GROWTH+FACTOR Search HEPARIN+BINDING+EPIDERMAL+GROWTH+FACTOR+LIKE+GROWTH+FACTOR
4 HEPARIN BINDING EGF LIKE GROWTH FACTOR 557367 3% 55% 27 Search HEPARIN+BINDING+EGF+LIKE+GROWTH+FACTOR Search HEPARIN+BINDING+EGF+LIKE+GROWTH+FACTOR
5 BETACELLULIN 391602 3% 37% 28 Search BETACELLULIN Search BETACELLULIN
6 EGF FAMILY 280975 2% 50% 15 Search EGF+FAMILY Search EGF+FAMILY
7 EPIREGULIN 269716 3% 30% 24 Search EPIREGULIN Search EPIREGULIN
8 CRM197 257777 2% 40% 17 Search CRM197 Search CRM197
9 HEPARIN BINDING EPIDERMAL GROWTH FACTOR 104056 1% 28% 10 Search HEPARIN+BINDING+EPIDERMAL+GROWTH+FACTOR Search HEPARIN+BINDING+EPIDERMAL+GROWTH+FACTOR
10 MEMBRANE ANCHORED GROWTH FACTOR 84295 0% 75% 3 Search MEMBRANE+ANCHORED+GROWTH+FACTOR Search MEMBRANE+ANCHORED+GROWTH+FACTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 BERASAIN, C , AVILA, MA , (2014) AMPHIREGULIN.SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. VOL. 28. ISSUE . P. 31 -41 72 43% 27
2 TAYLOR, SR , MARKESBERY, MG , HARDING, PA , (2014) HEPARIN-BINDING EPIDERMAL GROWTH FACTOR-LIKE GROWTH FACTOR (HB-EGF) AND PROTEOLYTIC PROCESSING BY A DISINTEGRIN AND METALLOPROTEINASES (ADAM): A REGULATOR OF SEVERAL PATHWAYS.SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. VOL. 28. ISSUE . P. 22 -30 64 45% 4
3 WILLMARTH, NE , ETHIER, SP , (2008) AMPHIREGULIN AS A NOVEL TARGET FOR BREAST CANCER THERAPY.JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA. VOL. 13. ISSUE 2. P. 171 -179 54 59% 20
4 HARRIS, RC , CHUNG, E , COFFEY, RJ , (2003) EGF RECEPTOR LIGANDS.EXPERIMENTAL CELL RESEARCH. VOL. 284. ISSUE 1. P. 2 -13 52 46% 413
5 BUSSER, B , SANCEY, L , BRAMBILLA, E , COLL, JL , HURBIN, A , (2011) THE MULTIPLE ROLES OF AMPHIREGULIN IN HUMAN CANCER.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1816. ISSUE 2. P. 119-131 64 36% 67
6 MIYAMOTO, S , YAGI, H , YOTSUMOTO, F , KAWARABAYASHI, T , MEKADA, E , (2006) HEPARIN-BINDING EPIDERMAL GROWTH FACTOR-LIKE GROWTH FACTOR AS A NOVEL TARGETING MOLECULE FOR CANCER THERAPY.CANCER SCIENCE. VOL. 97. ISSUE 5. P. 341-347 42 62% 87
7 SATO, S , KAMADA, H , WATANABE, T , TSUJI, I , FAN, JH , (2013) IDENTIFICATION OF THE CANCER CELL PROLIFERATION AND SURVIVAL FUNCTIONS OF PROHB-EGF BY USING AN ANTI-HB-EGF ANTIBODY.PLOS ONE. VOL. 8. ISSUE 1. P. - 31 79% 3
8 SATO, S , DRAKE, AW , TSUJI, I , FAN, JH , (2012) A POTENT ANTI-HB-EGF MONOCLONAL ANTIBODY INHIBITS CANCER CELL PROLIFERATION AND MULTIPLE ANGIOGENIC ACTIVITIES OF HB-EGF.PLOS ONE. VOL. 7. ISSUE 12. P. - 36 62% 10
9 RAAB, G , KLAGSBRUN, M , (1997) HEPARIN-BINDING EGF-LIKE GROWTH FACTOR.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1333. ISSUE 3. P. F179 -F199 64 43% 188
10 SUZUKI, K , MIZUSHIMA, H , ABE, H , IWAMOTO, R , NAKAMURA, H , MEKADA, E , (2015) IDENTIFICATION OF DIPHTHERIA TOXIN R DOMAIN MUTANTS WITH ENHANCED INHIBITORY ACTIVITY AGAINST HB-EGF.JOURNAL OF BIOCHEMISTRY. VOL. 157. ISSUE 5. P. 331 -343 31 67% 0

Classes with closest relation at Level 1


Rank Class id link
1 26980 CANC CAMPAIGN MED ONCOL UNIT//HTGF ALPHA//2ND SITE MUTATION
2 24202 ASTROGLIAL CELL CULTURES//NEUROSTATIN//RUBAM QUIM AVANCADA CATALUNYA
3 22222 CRIPTO 1//CRIPTO//TUMOR GROWTH TOR SECT
4 4433 NEUREGULIN//NEUREGULIN 1//ERBB4
5 6862 ADAM17//ADAM12//ADAM
6 5515 TRANSFORMING GROWTH FACTOR ALPHA//TGF ALPHA//TGF ALPHA ASE
7 37223 DIPARTIMENTO CARDIO TORACO VASCOLARE//ENVIRONM GENET ENVIRONM HLTH//IL17A SIGNALING PATHWAY
8 16892 GENISTEIN INHIBITION//TYROSINE KINASE//ANGIOTENSIN II
9 5087 EGF RECEPTOR//COMPUTER PROGRAM FOR MACINTOSHTMII//DIMERIZATION ARM
10 28999 PHARM PHARMACEUT HIGASHINADA KU//MED HOSP PHARM CHUO KU//RHEGF

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