Class information for:
Level 1: NEUREGULIN//NEUREGULIN 1//ERBB4

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4433 1786 50.2 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
652 2             HER2//TRASTUZUMAB//HER 2 NEU 13568
4433 1                   NEUREGULIN//NEUREGULIN 1//ERBB4 1786

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUREGULIN authKW 2184752 14% 53% 243
2 NEUREGULIN 1 authKW 1925987 9% 72% 156
3 ERBB4 authKW 1471743 8% 63% 137
4 ERBB3 authKW 828038 6% 47% 103
5 HEREGULIN authKW 756587 5% 49% 90
6 NRG1 authKW 466125 3% 49% 56
7 HER3 authKW 415761 3% 41% 60
8 ERBB RECEPTORS authKW 411625 4% 35% 68
9 HER4 authKW 268030 2% 56% 28
10 ERBB authKW 242193 4% 22% 64

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 5006 28% 0% 508
2 Cell Biology 3127 23% 0% 404
3 Neurosciences 2970 25% 0% 451
4 Biochemistry & Molecular Biology 1573 28% 0% 492
5 Psychiatry 639 8% 0% 140
6 Genetics & Heredity 550 9% 0% 154
7 Developmental Biology 144 2% 0% 39
8 Physiology 80 3% 0% 60
9 Pathology 77 3% 0% 46
10 Cardiac & Cardiovascular System 54 4% 0% 63

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MORPHOL IMAGING CORE 61052 0% 71% 5
2 INTER ADV STUDIES NEUROSCI 54703 0% 80% 4
3 HILLER ALS 34191 0% 100% 2
4 WHITAKER CARDIOVASC MOL ST S PONSE 34191 0% 100% 2
5 SECT MOL NEUROBIOL 34187 0% 50% 4
6 FUJIAN TRANSPLANT BIOL 30769 0% 60% 3
7 MOL NEUROBIOL SECT 25415 1% 9% 16
8 NEUROBIOL PATHOL PHYS MED REHABIL 22792 0% 67% 2
9 PROGRAM DEV NEUROBIOL 21755 1% 12% 11
10 ABO UNIV 17095 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOGENE 5372 4% 0% 76
2 JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA 3992 1% 2% 12
3 MOLECULAR PSYCHIATRY 2680 1% 1% 19
4 AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 2668 1% 1% 17
5 BREAST CANCER RESEARCH 2245 1% 1% 17
6 GROWTH FACTORS 1726 1% 1% 9
7 MOLECULAR AND CELLULAR NEUROSCIENCE 1541 1% 1% 16
8 CANCER JOURNAL FROM SCIENTIFIC AMERICAN 1219 0% 7% 1
9 JOURNAL OF NEUROSCIENCE 1043 3% 0% 47
10 JOURNAL OF BIOLOGICAL CHEMISTRY 961 6% 0% 99

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NEUREGULIN 2184752 14% 53% 243 Search NEUREGULIN Search NEUREGULIN
2 NEUREGULIN 1 1925987 9% 72% 156 Search NEUREGULIN+1 Search NEUREGULIN+1
3 ERBB4 1471743 8% 63% 137 Search ERBB4 Search ERBB4
4 ERBB3 828038 6% 47% 103 Search ERBB3 Search ERBB3
5 HEREGULIN 756587 5% 49% 90 Search HEREGULIN Search HEREGULIN
6 NRG1 466125 3% 49% 56 Search NRG1 Search NRG1
7 HER3 415761 3% 41% 60 Search HER3 Search HER3
8 ERBB RECEPTORS 411625 4% 35% 68 Search ERBB+RECEPTORS Search ERBB+RECEPTORS
9 HER4 268030 2% 56% 28 Search HER4 Search HER4
10 ERBB 242193 4% 22% 64 Search ERBB Search ERBB

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MEI, L , NAVE, KA , (2014) NEUREGULIN-ERBB SIGNALING IN THE NERVOUS SYSTEM AND NEUROPSYCHIATRIC DISEASES.NEURON. VOL. 83. ISSUE 1. P. 27 -49 165 57% 65
2 MEI, L , XIONG, WC , (2008) NEUREGULIN 1 IN NEURAL DEVELOPMENT, SYNAPTIC PLASTICITY AND SCHIZOPHRENIA.NATURE REVIEWS NEUROSCIENCE. VOL. 9. ISSUE 6. P. 437 -452 127 65% 451
3 DENG, C , PAN, B , ENGEL, M , HUANG, XF , (2013) NEUREGULIN-1 SIGNALLING AND ANTIPSYCHOTIC TREATMENT POTENTIAL THERAPEUTIC TARGETS IN A SCHIZOPHRENIA CANDIDATE SIGNALLING PATHWAY.PSYCHOPHARMACOLOGY. VOL. 226. ISSUE 2. P. 201 -215 112 74% 21
4 SITHANANDAM, G , ANDERSON, LM , (2008) THE ERBB3 RECEPTOR IN CANCER AND CANCER GENE THERAPY.CANCER GENE THERAPY. VOL. 15. ISSUE 7. P. 413 -448 184 44% 107
5 CARPENTER, G , (2003) ERBB-4: MECHANISM OF ACTION AND BIOLOGY.EXPERIMENTAL CELL RESEARCH. VOL. 284. ISSUE 1. P. 66-77 115 78% 150
6 BREULEUX, M , (2007) ROLE OF HEREGULIN IN HUMAN CANCER.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 64. ISSUE 18. P. 2358 -2377 140 64% 43
7 FALLS, DL , (2003) NEUREGULINS: FUNCTIONS, FORMS, AND SIGNALING STRATEGIES.EXPERIMENTAL CELL RESEARCH. VOL. 284. ISSUE 1. P. 14-30 100 60% 602
8 MOSTAID, MS , LLOYD, D , LIBERG, B , SUNDRAM, S , PEREIRA, A , PANTELIS, C , KARL, T , WEICKERT, CS , EVERALL, IP , BOUSMAN, CA , (2016) NEUREGULIN-1 AND SCHIZOPHRENIA IN THE GENOME-WIDE ASSOCIATION STUDY ERA.NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. VOL. 68. ISSUE . P. 387 -409 105 60% 2
9 PARODI, EM , KUHN, B , (2014) SIGNALLING BETWEEN MICROVASCULAR ENDOTHELIUM AND CARDIOMYOCYTES THROUGH NEUREGULIN.CARDIOVASCULAR RESEARCH. VOL. 102. ISSUE 2. P. 194 -204 96 63% 16
10 ODIETE, O , HILL, MF , SAWYER, DB , (2012) NEUREGULIN IN CARDIOVASCULAR DEVELOPMENT AND DISEASE.CIRCULATION RESEARCH. VOL. 111. ISSUE 10. P. 1376 -1385 66 71% 63

Classes with closest relation at Level 1


Rank Class id link
1 30546 NUCLEAR EGFR//EGFR FAMILY RECEPTORS//P TYR
2 36294 EBP1//ERBB3 BINDING PROTEIN 1//PA2G4
3 5180 C ERBB 2//HER 2 NEU//P185
4 13756 HB EGF//AMPHIREGULIN//HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR
5 2563 TRASTUZUMAB//LAPATINIB//PERTUZUMAB
6 19622 DISC1//DISRUPTED IN SCHIZOPHRENIA 1//FEZ1
7 5087 EGF RECEPTOR//COMPUTER PROGRAM FOR MACINTOSHTMII//DIMERIZATION ARM
8 8120 SCHWANN CELL//MYELINATION//SCHWANN CELL PRECURSORS
9 35026 M1B PROSTATE CANCER//BIOMARKER EPIDERMAL GROWTH FACTOR RECEPTOR EGFR//C ERB B 2 NEU GENE
10 26980 CANC CAMPAIGN MED ONCOL UNIT//HTGF ALPHA//2ND SITE MUTATION

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