Class information for:
Level 1: CANC CAMPAIGN MED ONCOL UNIT//HTGF ALPHA//2ND SITE MUTATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
26980 240 35.0 69%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
1648 2             EPIDERMAL GROWTH FACTOR//HB EGF//TRANSFORMING GROWTH FACTOR ALPHA 6893
26980 1                   CANC CAMPAIGN MED ONCOL UNIT//HTGF ALPHA//2ND SITE MUTATION 240

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANC CAMPAIGN MED ONCOL UNIT address 169639 1% 67% 2
2 HTGF ALPHA authKW 169639 1% 67% 2
3 2ND SITE MUTATION authKW 127231 0% 100% 1
4 3RD DISULFIDE LOOP authKW 127231 0% 100% 1
5 7 HYDROXY 1 2 3 4 TETRAHYDROISOQUINOLINE 3 CARBOXYLIC ACID authKW 127231 0% 100% 1
6 AFFINITY FUSION PROTEIN authKW 127231 0% 100% 1
7 ANGIOGENIC CYTOKINES PEPTIDES authKW 127231 0% 100% 1
8 AROMATIC CLUSTER OF HUMAN EGF authKW 127231 0% 100% 1
9 ASN32 OF HUMAN EGF authKW 127231 0% 100% 1
10 ASSISTED MODEL BUILDING WITH ENERGY REFINEMENT authKW 127231 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 2027 74% 0% 177
2 Biophysics 306 14% 0% 33
3 Biotechnology & Applied Microbiology 157 12% 0% 29
4 Biochemical Research Methods 150 9% 0% 22
5 Cell Biology 105 13% 0% 30
6 CYTOLOGY & HISTOLOGY 15 0% 0% 1
7 Biology 14 3% 0% 7
8 Endocrinology & Metabolism 13 4% 0% 10
9 Chemistry, Analytical 6 4% 0% 9
10 Chemistry, Applied 2 2% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANC CAMPAIGN MED ONCOL UNIT 169639 1% 67% 2
2 CNRS INSERM BIOCHIM STRUCT 127231 0% 100% 1
3 GRP REC DINFORMAT BIOMED 127231 0% 100% 1
4 PROTEIN STRUCT FUNCT DYNAM 127231 0% 100% 1
5 HERITAGE MED 713 81786 1% 21% 3
6 BIOL ESTRUCT COMPUTAC 63614 0% 50% 1
7 CHIRON S 42409 0% 33% 1
8 BIOTECNOL BIOMED VICENT VILLAR PALASI 31806 0% 25% 1
9 CRC MED ONCOL UNIT 25445 0% 20% 1
10 OAK RIDGE BIOMED SCI 23129 1% 9% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOPHARM-JOURNAL OF VETERINARY PHARMACY 16960 1% 7% 2
2 INTERFERON Y BIOTECNOLOGIA 4542 0% 4% 1
3 INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH 3241 3% 0% 8
4 PROTEIN ENGINEERING 2017 3% 0% 6
5 BIOCHEMISTRY 1594 11% 0% 26
6 GROWTH FACTORS 1436 1% 0% 3
7 JOURNAL OF BIOTECHNOLOGY 935 3% 0% 7
8 ACTA BIOCHIMICA ET BIOPHYSICA SINICA 739 2% 0% 4
9 JOURNAL OF CELLULAR BIOCHEMISTRY 349 2% 0% 5
10 BIOTECHNOLOGY TECHNIQUES 343 1% 0% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HTGF ALPHA 169639 1% 67% 2 Search HTGF+ALPHA Search HTGF+ALPHA
2 2ND SITE MUTATION 127231 0% 100% 1 Search 2ND+SITE+MUTATION Search 2ND+SITE+MUTATION
3 3RD DISULFIDE LOOP 127231 0% 100% 1 Search 3RD+DISULFIDE+LOOP Search 3RD+DISULFIDE+LOOP
4 7 HYDROXY 1 2 3 4 TETRAHYDROISOQUINOLINE 3 CARBOXYLIC ACID 127231 0% 100% 1 Search 7+HYDROXY+1+2+3+4+TETRAHYDROISOQUINOLINE+3+CARBOXYLIC+ACID Search 7+HYDROXY+1+2+3+4+TETRAHYDROISOQUINOLINE+3+CARBOXYLIC+ACID
5 AFFINITY FUSION PROTEIN 127231 0% 100% 1 Search AFFINITY+FUSION+PROTEIN Search AFFINITY+FUSION+PROTEIN
6 ANGIOGENIC CYTOKINES PEPTIDES 127231 0% 100% 1 Search ANGIOGENIC+CYTOKINES+PEPTIDES Search ANGIOGENIC+CYTOKINES+PEPTIDES
7 AROMATIC CLUSTER OF HUMAN EGF 127231 0% 100% 1 Search AROMATIC+CLUSTER+OF+HUMAN+EGF Search AROMATIC+CLUSTER+OF+HUMAN+EGF
8 ASN32 OF HUMAN EGF 127231 0% 100% 1 Search ASN32+OF+HUMAN+EGF Search ASN32+OF+HUMAN+EGF
9 ASSISTED MODEL BUILDING WITH ENERGY REFINEMENT 127231 0% 100% 1 Search ASSISTED+MODEL+BUILDING+WITH+ENERGY+REFINEMENT Search ASSISTED+MODEL+BUILDING+WITH+ENERGY+REFINEMENT
10 B LOOP FRAGMENT 127231 0% 100% 1 Search B+LOOP+FRAGMENT Search B+LOOP+FRAGMENT

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 GROENEN, LC , NICE, EC , BURGESS, AW , (1994) STRUCTURE-FUNCTION-RELATIONSHIPS FOR THE EGF/TGF-ALPHA FAMILY OF MITOGENS.GROWTH FACTORS. VOL. 11. ISSUE 4. P. 235-257 69 51% 179
2 MURRAY, MB , TADAKI, DK , CAMPION, SR , LAMERDIN, JA , SERPERSU, EH , BRADRICK, TD , NIYOGI, SK , (1998) STRUCTURE-FUNCTION ANALYSIS OF A CONSERVED AROMATIC CLUSTER IN THE N-TERMINAL DOMAIN OF HUMAN EPIDERMAL GROWTH FACTOR.PROTEIN ENGINEERING. VOL. 11. ISSUE 11. P. 1041 -1050 38 75% 6
3 CAMPION, SR , BIAMONTI, C , MONTELIONE, GT , NIYOGI, SK , (1993) THE ROLE OF ASPARAGINE-32 IN FORMING THE RECEPTOR-BINDING EPITOPE OF HUMAN EPIDERMAL GROWTH-FACTOR.PROTEIN ENGINEERING. VOL. 6. ISSUE 6. P. 651-659 21 100% 13
4 LESTER, CC , WANG, BY , WU, R , SCHERAGA, HA , (1995) STRUCTURE-FUNCTION STUDIES OF MEGF: PROBING THE TYPE I BETA-TURN BETWEEN RESIDUES 25 AND 26.JOURNAL OF PROTEIN CHEMISTRY. VOL. 14. ISSUE 8. P. 753-762 26 70% 0
5 MULLENBACH, GT , CHIU, CY , GYENES, A , BLANEY, J , ROSENBERG, S , MARLOWE, CK , BROWN, S , STRATTON-THOMAS, J , MONTELIONE, GT , GEORGE-NASCIMENTO, C , ET AL (1998) MODIFICATION OF A RECEPTOR-BINDING SURFACE OF EPIDERMAL GROWTH FACTOR (EGF): ANALOGS WITH ENHANCED RECEPTOR AFFINITY AT LOW PH OR AT NEUTRALITY.PROTEIN ENGINEERING. VOL. 11. ISSUE 6. P. 473 -480 31 52% 9
6 NANDAGOPAL, K , TADAKI, DK , LAMERDIN, JA , SERPERSU, EH , NIYOGI, SK , (1996) THE FUNCTIONAL IMPORTANCE OF LEU15 OF HUMAN EPIDERMAL GROWTH FACTOR IN RECEPTOR BINDING AND ACTIVATION.PROTEIN ENGINEERING. VOL. 9. ISSUE 9. P. 781-788 24 63% 8
7 TADAKI, DK , NIYOGI, SK , (1993) THE FUNCTIONAL IMPORTANCE OF HYDROPHOBICITY OF THE TYROSINE AT POSITION 13 OF HUMAN EPIDERMAL GROWTH-FACTOR IN RECEPTOR-BINDING.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 268. ISSUE 14. P. 10114-10119 20 77% 27
8 CAMPION, SR , NIYOGI, SK , (1994) INTERACTION OF EPIDERMAL GROWTH-FACTOR WITH ITS RECEPTOR.PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 49. VOL. 49. ISSUE . P. 353-383 37 39% 24
9 KOIDE, H , MUTO, Y , KASAI, H , HOSHI, K , TAKUSARI, H , KOHRI, K , TAKAHASHI, S , SASAKI, T , TSUKUMO, K , MIYAKE, T , ET AL (1992) RECOGNITION OF AN ANTIPARALLEL BETA-SHEET STRUCTURE OF HUMAN EPIDERMAL GROWTH-FACTOR BY ITS RECEPTOR - SITE-DIRECTED MUTAGENESIS STUDIES OF ALA-30 AND ASN-32.FEBS LETTERS. VOL. 302. ISSUE 1. P. 39-42 18 86% 10
10 ALEWOOD, D , NIELSEN, K , ALEWOOD, PF , CRAIK, DJ , ANDREWS, P , NERRIE, M , WHITE, S , DOMAGALA, T , WALKER, F , ROTHACKER, J , ET AL (2005) THE ROLE OF DISULFIDE BONDS IN THE STRUCTURE AND FUNCTION OF MURINE EPIDERMAL GROWTH FACTOR (MEGF).GROWTH FACTORS. VOL. 23. ISSUE 2. P. 97-110 27 36% 4

Classes with closest relation at Level 1


Rank Class id link
1 5087 EGF RECEPTOR//COMPUTER PROGRAM FOR MACINTOSHTMII//DIMERIZATION ARM
2 5515 TRANSFORMING GROWTH FACTOR ALPHA//TGF ALPHA//TGF ALPHA ASE
3 13756 HB EGF//AMPHIREGULIN//HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR
4 9806 EPIDERMAL GROWTH FACTOR//PIGEON MILK//TRANSFORMING GROWTH FACTOR ALPHA
5 28999 PHARM PHARMACEUT HIGASHINADA KU//MED HOSP PHARM CHUO KU//RHEGF
6 7907 DISTANCE GEOMETRY//JOURNAL OF MAGNETIC RESONANCE SERIES B//DGGTATACC2
7 34180 JWA//MOL CELL BIOL TOXICOL//TMEFF2
8 4433 NEUREGULIN//NEUREGULIN 1//ERBB4
9 11147 RENAL HYPERTROPHY//URINARY IGF I//KIDNEY GROWTH
10 26233 PLECTASIN//JIANGSU SUPERMOL MED MAT PLICAT//FUSION EXPRESSION

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