Class information for:
Level 1: TRANSFORMING GROWTH FACTOR ALPHA//TGF ALPHA//TGF ALPHA ASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5515 1612 36.6 76%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
317 3       HER2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA 39408
1648 2             EPIDERMAL GROWTH FACTOR//HB EGF//TRANSFORMING GROWTH FACTOR ALPHA 6893
5515 1                   TRANSFORMING GROWTH FACTOR ALPHA//TGF ALPHA//TGF ALPHA ASE 1612

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TRANSFORMING GROWTH FACTOR ALPHA authKW 262190 5% 16% 86
2 TGF ALPHA authKW 150532 4% 12% 64
3 TGF ALPHA ASE authKW 56822 0% 100% 3
4 EGF RECEPTOR authKW 47929 3% 5% 49
5 EPIDERMAL GROWTH FACTOR RECEPTOR authKW 46978 6% 3% 96
6 ANTI TGF ALPHA ANTIBODY authKW 37882 0% 100% 2
7 COGNATE PEPTIDE SUBSTRATE authKW 37882 0% 100% 2
8 EGF RECEPTOR ANTIBODY authKW 37882 0% 100% 2
9 PREPROTGF ALPHA authKW 37882 0% 100% 2
10 TUMOR IMMUNOL BIOL BLDG 10 ROOM 5B39 address 37882 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 11662 44% 0% 713
2 Cell Biology 1748 18% 0% 295
3 Biochemistry & Molecular Biology 845 23% 0% 363
4 Pathology 776 7% 0% 110
5 CYTOLOGY & HISTOLOGY 340 1% 0% 12
6 Physiology 128 4% 0% 66
7 Endocrinology & Metabolism 106 4% 0% 71
8 Obstetrics & Gynecology 86 3% 0% 49
9 Biophysics 82 4% 0% 60
10 Dermatology 58 2% 0% 32

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TUMOR IMMUNOL BIOL BLDG 10 ROOM 5B39 37882 0% 100% 2
2 QCF CANC UNIT 25253 0% 67% 2
3 NANOSSENSO 24349 0% 43% 3
4 100 ST 18941 0% 100% 1
5 BANTING CLIN BIOCHEMROOM 414 18941 0% 100% 1
6 BIOTECHNOL CELLULES EUCARYOTES 18941 0% 100% 1
7 CANC EXPTL THER EUT BIOPHYS 18941 0% 100% 1
8 CIBA CORNING DIAGNOST 18941 0% 100% 1
9 CLIN ENDOCRINOL INTERNAL MED 18941 0% 100% 1
10 CLIN TEACHING SECT 18941 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER RESEARCH 8470 8% 0% 133
2 EKSPERIMENTALNAYA ONKOLOGIYA 5495 1% 2% 19
3 BREAST CANCER RESEARCH AND TREATMENT 4128 2% 1% 40
4 JOURNAL OF CELLULAR PHYSIOLOGY 3422 3% 0% 43
5 INTERFERON Y BIOTECNOLOGIA 2702 0% 7% 2
6 CELL GROWTH & DIFFERENTIATION 2613 1% 1% 14
7 JOURNAL OF CELLULAR BIOCHEMISTRY 2405 2% 0% 34
8 BRITISH JOURNAL OF CANCER 2368 3% 0% 48
9 INTERNATIONAL JOURNAL OF CANCER 2276 3% 0% 50
10 ANTICANCER RESEARCH 1604 3% 0% 41

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TRANSFORMING GROWTH FACTOR ALPHA 262190 5% 16% 86 Search TRANSFORMING+GROWTH+FACTOR+ALPHA Search TRANSFORMING+GROWTH+FACTOR+ALPHA
2 TGF ALPHA 150532 4% 12% 64 Search TGF+ALPHA Search TGF+ALPHA
3 TGF ALPHA ASE 56822 0% 100% 3 Search TGF+ALPHA+ASE Search TGF+ALPHA+ASE
4 EGF RECEPTOR 47929 3% 5% 49 Search EGF+RECEPTOR Search EGF+RECEPTOR
5 EPIDERMAL GROWTH FACTOR RECEPTOR 46978 6% 3% 96 Search EPIDERMAL+GROWTH+FACTOR+RECEPTOR Search EPIDERMAL+GROWTH+FACTOR+RECEPTOR
6 ANTI TGF ALPHA ANTIBODY 37882 0% 100% 2 Search ANTI+TGF+ALPHA+ANTIBODY Search ANTI+TGF+ALPHA+ANTIBODY
7 COGNATE PEPTIDE SUBSTRATE 37882 0% 100% 2 Search COGNATE+PEPTIDE+SUBSTRATE Search COGNATE+PEPTIDE+SUBSTRATE
8 EGF RECEPTOR ANTIBODY 37882 0% 100% 2 Search EGF+RECEPTOR+ANTIBODY Search EGF+RECEPTOR+ANTIBODY
9 PREPROTGF ALPHA 37882 0% 100% 2 Search PREPROTGF+ALPHA Search PREPROTGF+ALPHA
10 DENSITY DEPENDENT GROWTH INHIBITION 34091 0% 60% 3 Search DENSITY+DEPENDENT+GROWTH+INHIBITION Search DENSITY+DEPENDENT+GROWTH+INHIBITION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LEE, DC , FENTON, SE , BERKOWITZ, EA , HISSONG, MA , (1995) TRANSFORMING GROWTH-FACTOR-ALPHA - EXPRESSION, REGULATION, AND BIOLOGICAL-ACTIVITIES.PHARMACOLOGICAL REVIEWS. VOL. 47. ISSUE 1. P. 51-85 158 51% 150
2 KLIJN, JGM , BERNS, PMJJ , SCHMITZ, PIM , FOEKENS, JA , (1992) THE CLINICAL-SIGNIFICANCE OF EPIDERMAL GROWTH-FACTOR RECEPTOR (EGF-R) IN HUMAN BREAST-CANCER - A REVIEW ON 5232 PATIENTS.ENDOCRINE REVIEWS. VOL. 13. ISSUE 1. P. 3-17 54 68% 482
3 MODJTAHEDI, H , DEAN, C , (1994) THE RECEPTOR FOR EGF AND ITS LIGANDS - EXPRESSION, PROGNOSTIC VALUE AND TARGET FOR THERAPY IN CANCER (REVIEW).INTERNATIONAL JOURNAL OF ONCOLOGY. VOL. 4. ISSUE 2. P. 277-296 114 40% 120
4 MOSKAL, TL , HUANG, SA , ELLIS, LM , FRITSCHE, HA , CHAKRABARTY, S , (1995) SERUM LEVELS OF TRANSFORMING GROWTH-FACTOR-ALPHA IN GASTROINTESTINAL CANCER-PATIENTS.CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION. VOL. 4. ISSUE 2. P. 127-131 54 89% 41
5 PHYLCHENKOV, AA , (1993) TRANSFORMING GROWTH-FACTOR-ALPHA IN ONCOLOGY - CURRENT STATUS AND FUTURE-PROSPECTS.EKSPERIMENTALNAYA ONKOLOGIYA. VOL. 15. ISSUE 4. P. 3-19 96 57% 1
6 DERYNCK, R , (1992) THE PHYSIOLOGY OF TRANSFORMING GROWTH-FACTOR-ALPHA.ADVANCES IN CANCER RESEARCH. VOL. 58. ISSUE . P. 27-52 60 61% 257
7 FOX, SB , HARRIS, AL , (1997) THE EPIDERMAL GROWTH FACTOR RECEPTOR IN BREAST CANCER.JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA. VOL. 2. ISSUE 2. P. 131-141 57 58% 52
8 STROMBERG, K , COLLINS, TJ , GORDON, AW , JACKSON, CL , JOHNSON, GR , (1992) TRANSFORMING GROWTH FACTOR-ALPHA ACTS AS AN AUTOCRINE GROWTH-FACTOR IN OVARIAN-CARCINOMA CELL-LINES.CANCER RESEARCH. VOL. 52. ISSUE 2. P. 341-347 48 77% 84
9 SANDGREN, EP , LUETTEKE, NC , PALMITER, RD , BRINSTER, RL , LEE, DC , (1990) OVEREXPRESSION OF TGF-ALPHA IN TRANSGENIC MICE - INDUCTION OF EPITHELIAL HYPERPLASIA, PANCREATIC METAPLASIA, AND CARCINOMA OF THE BREAST.CELL. VOL. 61. ISSUE 6. P. 1121-1135 41 59% 601
10 BATES, SE , DAVIDSON, NE , VALVERIUS, EM , FRETER, CE , DICKSON, RB , TAM, JP , KUDLOW, JE , LIPPMAN, ME , SALOMON, DS , (1988) EXPRESSION OF TRANSFORMING GROWTH FACTOR-ALPHA AND ITS MESSENGER RIBONUCLEIC-ACID IN HUMAN-BREAST CANCER - ITS REGULATION BY ESTROGEN AND ITS POSSIBLE FUNCTIONAL-SIGNIFICANCE.MOLECULAR ENDOCRINOLOGY. VOL. 2. ISSUE 6. P. 543-555 35 76% 349

Classes with closest relation at Level 1


Rank Class id link
1 26980 CANC CAMPAIGN MED ONCOL UNIT//HTGF ALPHA//2ND SITE MUTATION
2 5087 EGF RECEPTOR//COMPUTER PROGRAM FOR MACINTOSHTMII//DIMERIZATION ARM
3 35653 MD ANDERSON CANC MED//BIOSSCI TECHNOL//DIFFERENTIATION INDUCING EFFECT
4 9806 EPIDERMAL GROWTH FACTOR//PIGEON MILK//TRANSFORMING GROWTH FACTOR ALPHA
5 13756 HB EGF//AMPHIREGULIN//HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR
6 34628 EGF POLYMORPHISM//EPIDERMAL GROWTH FACTOR POLYMORPHISMS//CRYPTOMPHALUS ASPERSA
7 37223 DIPARTIMENTO CARDIO TORACO VASCOLARE//ENVIRONM GENET ENVIRONM HLTH//IL17A SIGNALING PATHWAY
8 24202 ASTROGLIAL CELL CULTURES//NEUROSTATIN//RUBAM QUIM AVANCADA CATALUNYA
9 1881 TGF BETA RECEPTORS//TRANSFORMING GROWTH FACTOR BETA//TGF BETA
10 4440 NIMOTUZUMAB//CETUXIMAB//EGFR

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