Class information for:
Level 1: PROTEIN SWITCH//CIRCULAR PERMUTATION//BIOMED ST PAU IIB SANTPAU

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
25675 275 38.5 81%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
219 3       PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS//PROTEIN FOLDING//PROTEIN STRUCTURE PREDICTION 50409
1067 2             ANGIOGENIN//RIBONUCLEASE//MOLTEN GLOBULE 9981
25675 1                   PROTEIN SWITCH//CIRCULAR PERMUTATION//BIOMED ST PAU IIB SANTPAU 275

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROTEIN SWITCH authKW 639563 4% 48% 12
2 CIRCULAR PERMUTATION authKW 543841 8% 21% 23
3 BIOMED ST PAU IIB SANTPAU address 355318 1% 80% 4
4 ONCOGENESIS ANTITUMOR DRUG GRP address 307482 2% 46% 6
5 DOMAIN INSERTION authKW 231322 2% 42% 5
6 ALTERNATE FRAME FOLDING authKW 222075 1% 100% 2
7 BIOMED ST PAU IIB STPAU address 222075 1% 100% 2
8 PERMUTEIN authKW 222075 1% 100% 2
9 REDUNDANT AND DELETED RESIDUES authKW 222075 1% 100% 2
10 ARTIFICIAL VIRUSES authKW 222071 1% 50% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 995 50% 0% 138
2 Biotechnology & Applied Microbiology 377 17% 0% 46
3 Biophysics 194 11% 0% 29
4 Biochemical Research Methods 101 7% 0% 20
5 Chemistry, Multidisciplinary 81 14% 0% 38
6 Water Resources 76 5% 0% 14
7 Nanoscience & Nanotechnology 49 5% 0% 15
8 Chemistry, Medicinal 19 3% 0% 9
9 Cell Biology 9 5% 0% 14
10 Medicine, Research & Experimental 8 3% 0% 9

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOMED ST PAU IIB SANTPAU 355318 1% 80% 4
2 ONCOGENESIS ANTITUMOR DRUG GRP 307482 2% 46% 6
3 BIOMED ST PAU IIB STPAU 222075 1% 100% 2
4 BIOTECNOL BIOMED 210167 13% 5% 35
5 INTER PROGRAM BIOMOL SCI ENGN 144187 4% 13% 10
6 BIOL FONAMENTAL 137818 4% 10% 12
7 BIOSENSORS NANOMACHINES 118434 1% 27% 4
8 AUSTRALIAN BIOENGN NANOTECLMOL 111037 0% 100% 1
9 BIOCHEM FUNDAMENTAL PL MOL EVOLUT 111037 0% 100% 1
10 BIOCHIM GENET MOL BACTERIENNE 111037 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROTEIN ENGINEERING DESIGN & SELECTION 3839 2% 1% 6
2 PROTEIN SCIENCE 3455 5% 0% 14
3 ACS SYNTHETIC BIOLOGY 1788 1% 1% 3
4 GROUND WATER 1408 2% 0% 6
5 NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE 1379 1% 0% 4
6 PROTEIN ENGINEERING 1220 2% 0% 5
7 BIOTECHNOLOGY AND BIOENGINEERING 756 3% 0% 9
8 TRENDS IN BIOTECHNOLOGY 720 1% 0% 4
9 CHEMBIOCHEM 616 2% 0% 5
10 MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT 608 0% 1% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PROTEIN SWITCH 639563 4% 48% 12 Search PROTEIN+SWITCH Search PROTEIN+SWITCH
2 CIRCULAR PERMUTATION 543841 8% 21% 23 Search CIRCULAR+PERMUTATION Search CIRCULAR+PERMUTATION
3 DOMAIN INSERTION 231322 2% 42% 5 Search DOMAIN+INSERTION Search DOMAIN+INSERTION
4 ALTERNATE FRAME FOLDING 222075 1% 100% 2 Search ALTERNATE+FRAME+FOLDING Search ALTERNATE+FRAME+FOLDING
5 PERMUTEIN 222075 1% 100% 2 Search PERMUTEIN Search PERMUTEIN
6 REDUNDANT AND DELETED RESIDUES 222075 1% 100% 2 Search REDUNDANT+AND+DELETED+RESIDUES Search REDUNDANT+AND+DELETED+RESIDUES
7 ARTIFICIAL VIRUSES 222071 1% 50% 4 Search ARTIFICIAL+VIRUSES Search ARTIFICIAL+VIRUSES
8 ALLOSTERIC BIOSENSOR 111037 0% 100% 1 Search ALLOSTERIC+BIOSENSOR Search ALLOSTERIC+BIOSENSOR
9 ALLOSTERIC PROTEIN SWITCHES 111037 0% 100% 1 Search ALLOSTERIC+PROTEIN+SWITCHES Search ALLOSTERIC+PROTEIN+SWITCHES
10 AMPEROMETRY OF 4 AMINOPHENOL 111037 0% 100% 1 Search AMPEROMETRY+OF+4+AMINOPHENOL Search AMPEROMETRY+OF+4+AMINOPHENOL

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 STRATTON, MM , LOH, SN , (2011) CONVERTING A PROTEIN INTO A SWITCH FOR BIOSENSING AND FUNCTIONAL REGULATION.PROTEIN SCIENCE. VOL. 20. ISSUE 1. P. 19 -29 28 35% 24
2 YU, Y , LUTZ, S , (2011) CIRCULAR PERMUTATION: A DIFFERENT WAY TO ENGINEER ENZYME STRUCTURE AND FUNCTION.TRENDS IN BIOTECHNOLOGY. VOL. 29. ISSUE 1. P. 18-25 26 34% 40
3 FERRAZ, RM , VERA, A , ARIS, A , VILLAVERDE, A , (2006) INSERTIONAL PROTEIN ENGINEERING FOR ANALYTICAL MOLECULAR SENSING.MICROBIAL CELL FACTORIES. VOL. 5. ISSUE . P. - 25 44% 11
4 BANALA, S , ARTS, R , APER, SJA , MERKX, M , (2013) NO WASHING, LESS WAITING: ENGINEERING BIOMOLECULAR REPORTERS FOR SINGLE-STEP ANTIBODY DETECTION IN SOLUTION.ORGANIC & BIOMOLECULAR CHEMISTRY. VOL. 11. ISSUE 44. P. 7642-7649 18 47% 4
5 KANWAR, M , WRIGHT, RC , DATE, A , TULLMAN, J , OSTERMEIER, M , (2013) PROTEIN SWITCH ENGINEERING BY DOMAIN INSERTION.METHODS IN PROTEIN DESIGN. VOL. 523. ISSUE . P. 369-388 12 67% 10
6 CAZORLA, D , FELIU, JX , FERRER-MIRALLES, N , VILLAVERDE, A , (2002) TAILORING MOLECULAR SENSING FOR PEPTIDE DISPLAYING ENGINEERED ENZYMES.BIOTECHNOLOGY LETTERS. VOL. 24. ISSUE 6. P. 469-477 16 70% 1
7 WANG, Q , WANG, Y , CHEN, GJ , (2016) INFLUENCE OF SECONDARY-STRUCTURE FOLDING ON THE MUTUALLY EXCLUSIVE FOLDING PROCESS OF GL5/I27 PROTEIN: EVIDENCE FROM MOLECULAR DYNAMICS SIMULATIONS.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 17. ISSUE 11. P. - 21 37% 0
8 GOLYNSKIY, MV , KOAY, MS , VINKENBORG, JL , MERKX, M , (2011) ENGINEERING PROTEIN SWITCHES: SENSORS, REGULATORS, AND SPARE PARTS FOR BIOLOGY AND BIOTECHNOLOGY.CHEMBIOCHEM. VOL. 12. ISSUE 3. P. 353-361 28 28% 23
9 PIERRE, B , SHAH, V , XIAO, J , KIM, JR , (2015) CONSTRUCTION OF A RANDOM CIRCULAR PERMUTATION LIBRARY USING AN ENGINEERED TRANSPOSON.ANALYTICAL BIOCHEMISTRY. VOL. 474. ISSUE . P. 16 -24 17 45% 1
10 FERRAZ, RM , ARIS, A , VILLAVERDE, A , (2006) ENHANCED MOLECULAR RECOGNITION SIGNAL IN ALLOSTERIC BIOSENSING BY PROPER SUBSTRATE SELECTION.BIOTECHNOLOGY AND BIOENGINEERING. VOL. 94. ISSUE 1. P. 193-199 12 80% 4

Classes with closest relation at Level 1


Rank Class id link
1 35810 BIFUNCTIONAL FUSION ENZYME//CELM2//END TO END FUSION
2 8564 PERIPLASMIC BINDING PROTEIN//BIOL BAKTERIENPHYSIOL//MALTOSE TRANSPORT
3 14228 BIMOLECULAR FLUORESCENCE COMPLEMENTATION//SPLIT UBIQUITIN//PROTEIN FRAGMENT COMPLEMENTATION ASSAY
4 10945 DIRECTED EVOLUTION//DNA SHUFFLING//RANDOM MUTAGENESIS
5 22175 HISTIDINE BIOSYNTHESIS//BETA ALPHA8 BARREL//INDOLE 3 GLYCEROL PHOSPHATE SYNTHASE
6 18905 REPEAT PROTEIN//FN3//ANKYRIN REPEAT
7 15175 STAPHYLOCOCCAL NUCLEASE//THERMODYNAMIC MOLECULAR SWITCH//T4 LYSOZYME
8 8575 DIHYDROFOLATE REDUCTASE//DHFR//10065 BARNES CANYON RD
9 15112 ALPHA SARCIN//RIBOTOXIN//RIBONUCLEASE T1
10 13291 COMPUTATIONAL PROTEIN DESIGN//PROTEIN DESIGN//DEAD END ELIMINATION

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