Class information for:
Level 1: STAPHYLOCOCCAL NUCLEASE//THERMODYNAMIC MOLECULAR SWITCH//T4 LYSOZYME

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15175 727 39.6 72%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
219 3       PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS//PROTEIN FOLDING//PROTEIN STRUCTURE PREDICTION 50409
1067 2             ANGIOGENIN//RIBONUCLEASE//MOLTEN GLOBULE 9981
15175 1                   STAPHYLOCOCCAL NUCLEASE//THERMODYNAMIC MOLECULAR SWITCH//T4 LYSOZYME 727

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STAPHYLOCOCCAL NUCLEASE authKW 938531 7% 43% 52
2 THERMODYNAMIC MOLECULAR SWITCH authKW 210003 1% 100% 5
3 T4 LYSOZYME authKW 178477 2% 25% 17
4 INNATE TEMPERATURE INVARIANT ENTHALPY authKW 168002 1% 100% 4
5 PROTEIN STABILITY authKW 131511 12% 4% 88
6 PLANCK BENZINGER THERMAL WORK FUNCTION authKW 126002 0% 100% 3
7 SEQUENCE DUPLICATION authKW 111999 1% 67% 4
8 N TERMINAL FRAGMENT authKW 95990 1% 29% 8
9 BARLEY CHYMOTRYPSIN INHIBITOR 2 authKW 84001 0% 100% 2
10 CA2 BINDING TO authKW 84001 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 7572 81% 0% 591
2 Biophysics 1751 18% 0% 134
3 Biochemical Research Methods 281 7% 0% 54
4 Genetics & Heredity 15 3% 0% 25
5 Mathematics, Interdisciplinary Applications 15 2% 0% 11
6 Biology 10 2% 0% 13
7 Chemistry, Physical 9 6% 0% 43
8 Mathematical & Computational Biology 9 1% 0% 7
9 Biotechnology & Applied Microbiology 8 3% 0% 22
10 Chemistry, Multidisciplinary 3 5% 0% 35

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHYS 1229 55999 0% 67% 2
2 BIOCALORIMETRY 51439 1% 18% 7
3 ANAT HISTOL FORENS MED ORTHOPAED S IENZA 42001 0% 100% 1
4 BASS MOLEC BIOPHYS BIOCHEM 42001 0% 100% 1
5 CIENCIAS BIOCOMP 42001 0% 100% 1
6 NANO BIOMEMD MEMS TECHNOL 42001 0% 100% 1
7 SERV BIOPHYS MOL CELLULAIRE 42001 0% 100% 1
8 HOWARD HUGHES MED MOLEC BIOL 27998 0% 33% 2
9 CHEM BIOL UNIT 22269 2% 5% 11
10 AG PARASKEVI ATTIKIS 20999 0% 50% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROTEINS-STRUCTURE FUNCTION AND GENETICS 24186 2% 4% 16
2 PROTEIN SCIENCE 22499 8% 1% 58
3 BIOCHEMISTRY 14166 18% 0% 134
4 PROTEIN ENGINEERING 13513 4% 1% 27
5 JOURNAL OF MOLECULAR BIOLOGY 12391 11% 0% 83
6 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 11571 6% 1% 42
7 FOLDING & DESIGN 3789 1% 2% 4
8 ADVANCES IN PROTEIN CHEMISTRY 2047 1% 1% 4
9 BIOPHYSICAL CHEMISTRY 1655 2% 0% 13
10 PROTEIN AND PEPTIDE LETTERS 1046 1% 0% 8

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 STAPHYLOCOCCAL NUCLEASE 938531 7% 43% 52 Search STAPHYLOCOCCAL+NUCLEASE Search STAPHYLOCOCCAL+NUCLEASE
2 THERMODYNAMIC MOLECULAR SWITCH 210003 1% 100% 5 Search THERMODYNAMIC+MOLECULAR+SWITCH Search THERMODYNAMIC+MOLECULAR+SWITCH
3 T4 LYSOZYME 178477 2% 25% 17 Search T4+LYSOZYME Search T4+LYSOZYME
4 INNATE TEMPERATURE INVARIANT ENTHALPY 168002 1% 100% 4 Search INNATE+TEMPERATURE+INVARIANT+ENTHALPY Search INNATE+TEMPERATURE+INVARIANT+ENTHALPY
5 PROTEIN STABILITY 131511 12% 4% 88 Search PROTEIN+STABILITY Search PROTEIN+STABILITY
6 PLANCK BENZINGER THERMAL WORK FUNCTION 126002 0% 100% 3 Search PLANCK+BENZINGER+THERMAL+WORK+FUNCTION Search PLANCK+BENZINGER+THERMAL+WORK+FUNCTION
7 SEQUENCE DUPLICATION 111999 1% 67% 4 Search SEQUENCE+DUPLICATION Search SEQUENCE+DUPLICATION
8 N TERMINAL FRAGMENT 95990 1% 29% 8 Search N+TERMINAL+FRAGMENT Search N+TERMINAL+FRAGMENT
9 BARLEY CHYMOTRYPSIN INHIBITOR 2 84001 0% 100% 2 Search BARLEY+CHYMOTRYPSIN+INHIBITOR+2 Search BARLEY+CHYMOTRYPSIN+INHIBITOR+2
10 CA2 BINDING TO 84001 0% 100% 2 Search CA2+BINDING+TO Search CA2+BINDING+TO

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 PUCCI, F , BOURGEAS, R , ROOMAN, M , (2016) HIGH-QUALITY THERMODYNAMIC DATA ON THE STABILITY CHANGES OF PROTEINS UPON SINGLE-SITE MUTATIONS.JOURNAL OF PHYSICAL AND CHEMICAL REFERENCE DATA. VOL. 45. ISSUE 2. P. - 79 31% 0
2 FUNAHASHI, J , TAKANO, K , YUTANI, K , (2001) ARE THE PARAMETERS OF VARIOUS STABILIZATION FACTORS ESTIMATED FROM MUTANT HUMAN LYSOZYMES COMPATIBLE WITH OTHER PROTEINS?.PROTEIN ENGINEERING. VOL. 14. ISSUE 2. P. 127 -134 40 75% 35
3 BAASE, WA , LIU, LJ , TRONRUD, DE , MATTHEWS, BW , (2010) LESSONS FROM THE LYSOZYME OF PHAGE T4.PROTEIN SCIENCE. VOL. 19. ISSUE 4. P. 631-641 34 55% 67
4 ZHANG, HJ , HUANG, S , FENG, YM , GUO, P , JING, GZ , (2005) EFFECT OF N-TERMINAL DELETIONS ON THE FOLDABILITY, STABILITY, AND ACTIVITY OF STAPHYLOCOCCAL NUCLEASE.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 441. ISSUE 2. P. 123-131 27 87% 8
5 HU, HY , WU, MC , FANG, HJ , FORREST, MD , HU, CK , TSONG, TY , CHEN, HM , (2010) THE ROLE OF TRYPTOPHAN IN STAPHYLOCOCCAL NUCLEASE STABILITY.BIOPHYSICAL CHEMISTRY. VOL. 151. ISSUE 3. P. 170-177 21 88% 6
6 TALLA, D , STITES, WE , (2013) THE FLUORESCENCE DETECTED GUANIDINE HYDROCHLORIDE EQUILIBRIUM DENATURATION OF WILD-TYPE STAPHYLOCOCCAL NUCLEASE DOES NOT FIT A THREE-STATE UNFOLDING MODEL.BIOCHIMIE. VOL. 95. ISSUE 7. P. 1386-1393 19 86% 0
7 BYRNE, MP , STITES, WE , (2007) THERMAL DENATURATIONS OF STAPHYLOCOCCAL NUCLEASE WILD-TYPE AND MUTANTS MONITORED BY FLUORESCENCE AND CIRCULAR DICHROISM ARE SIMILAR: LACK OF EVIDENCE FOR OTHER THAN A TWO STATE THERMAL DENATURATION.BIOPHYSICAL CHEMISTRY. VOL. 125. ISSUE 2-3. P. 490 -496 24 75% 2
8 TAKANO, K , YAMAGATA, Y , YUTANI, K , (2003) BURIED WATER MOLECULES CONTRIBUTE TO THE CONFORMATIONAL STABILITY OF A PROTEIN.PROTEIN ENGINEERING. VOL. 16. ISSUE 1. P. 5 -9 27 69% 44
9 CHEN, JM , STITES, WE , (2001) ENERGETICS OF SIDE CHAIN PACKING IN STAPHYLOCOCCAL NUCLEASE ASSESSED BY SYSTEMATIC DOUBLE MUTANT CYCLES.BIOCHEMISTRY. VOL. 40. ISSUE 46. P. 14004-14011 31 66% 26
10 LOLADZE, VV , ERMOLENKO, DN , MAKHATADZE, GI , (2002) THERMODYNAMIC CONSEQUENCES OF BURIAL OF POLAR AND NON-POLAR AMINO ACID RESIDUES IN THE PROTEIN INTERIOR.JOURNAL OF MOLECULAR BIOLOGY. VOL. 320. ISSUE 2. P. 343-357 45 41% 64

Classes with closest relation at Level 1


Rank Class id link
1 16095 BPTI//BAKER CHEM CHEM BIOL//BOVINE PANCREATIC TRYPSIN INHIBITOR
2 26332 CYSTEINE BONDING STATE//DISULFIDE CONNECTIVITY PREDICTION//MEDIUM AND LONG RANGE
3 12643 PSYCHROPHILE//COLD ADAPTATION//THERMOPHILIC PROTEIN
4 37505 14 RESIDUE PEPTIDES//AMIDE TO E OLEFIN MUTATION//AMIDE TO ESTER MUTATION
5 7436 ALPHA HELIX//ALPHA HELIX STABILITY//N CAP
6 5455 MOLTEN GLOBULE//ALPHA LACTALBUMIN//APOMYOGLOBIN
7 23925 WATERMAP//CAMBRIDGE MOL THER EUT PROGRAMME//PROTEIN HYDRATION
8 21813 THERMOLYSIN//NEUTRAL PROTEASE//HALOPHILICITY
9 573 PROTEIN FOLDING//PHI VALUE//FOLDING RATE
10 15112 ALPHA SARCIN//RIBOTOXIN//RIBONUCLEASE T1

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