Class information for:
Level 1: CYCLOPENTENYL CYTOSINE//CTP SYNTHASE//CTP SYNTHETASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
23401 347 33.2 59%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
236 3       ADENOSINE//NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//ADENOSINE RECEPTORS 48331
2798 2             LEFLUNOMIDE//MIZORIBINE//DIHYDROOROTATE DEHYDROGENASE 3097
23401 1                   CYCLOPENTENYL CYTOSINE//CTP SYNTHASE//CTP SYNTHETASE 347

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYCLOPENTENYL CYTOSINE authKW 2036975 7% 93% 25
2 CTP SYNTHASE authKW 1949479 7% 92% 24
3 CTP SYNTHETASE authKW 1448172 7% 69% 24
4 CYTOOPHIDIUM authKW 967972 3% 100% 11
5 CYTIDINE TRIPHOSPHATE SYNTHETASE authKW 703980 2% 100% 8
6 CPEC authKW 625758 2% 89% 8
7 3 DEAZAURIDINE authKW 351990 1% 100% 4
8 CYTOOPHIDIA authKW 281590 1% 80% 4
9 CTPS authKW 263992 1% 100% 3
10 RODS AND RINGS authKW 263992 1% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 1090 30% 0% 104
2 Biochemistry & Molecular Biology 654 38% 0% 131
3 Pharmacology & Pharmacy 236 17% 0% 60
4 Biophysics 58 6% 0% 20
5 Cell Biology 39 7% 0% 26
6 Chemistry, Medicinal 35 4% 0% 13
7 Genetics & Heredity 33 5% 0% 19
8 Hematology 20 3% 0% 11
9 Biochemical Research Methods 15 3% 0% 11
10 Medicine, Research & Experimental 7 3% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ACTIVAT LYMPHOCYTAIRE SUSCEPTIBILITE EBV 87997 0% 100% 1
2 CRYSTALLOGR HIC STUDIES 87997 0% 100% 1
3 GENET METAB DISEMMA KINDERZIEKENHUIS AMC 87997 0% 100% 1
4 HEMATOLEMMA KINDERZIEKENHUIS AMC 87997 0% 100% 1
5 INTEGRATED PROT SCI CIPSM ADV STUDIES IA 87997 0% 100% 1
6 MED CHEM PHARMACOL DRUG DESIGN CHEM SECT 87997 0% 100% 1
7 MED EMMA KINDERZIEKENHUIS AMC 87997 0% 100% 1
8 PAEDIAT ONCOLEMMA KINDERZIEKENHUIS AMC 87997 0% 100% 1
9 PEDIATEMMA KINDERZIEKENHUIS AMC 87997 0% 100% 1
10 PLATEFORME VECTEURS VIRAUX TRANSFERT GENES 87997 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER TREATMENT REPORTS 14402 5% 1% 19
2 ADVANCES IN ENZYME REGULATION 5303 2% 1% 6
3 INVESTIGATIONAL NEW DRUGS 4159 3% 0% 11
4 JOURNAL OF GENETICS AND GENOMICS 3712 1% 1% 5
5 BIOCHEMICAL PHARMACOLOGY 1884 6% 0% 20
6 CANCER RESEARCH 1168 7% 0% 23
7 SOMATIC CELL AND MOLECULAR GENETICS 869 1% 0% 3
8 CANCER CLINICAL TRIALS 685 0% 1% 1
9 ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY 622 1% 0% 2
10 CHEMMEDCHEM 608 1% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CYCLOPENTENYL CYTOSINE 2036975 7% 93% 25 Search CYCLOPENTENYL+CYTOSINE Search CYCLOPENTENYL+CYTOSINE
2 CTP SYNTHASE 1949479 7% 92% 24 Search CTP+SYNTHASE Search CTP+SYNTHASE
3 CTP SYNTHETASE 1448172 7% 69% 24 Search CTP+SYNTHETASE Search CTP+SYNTHETASE
4 CYTOOPHIDIUM 967972 3% 100% 11 Search CYTOOPHIDIUM Search CYTOOPHIDIUM
5 CYTIDINE TRIPHOSPHATE SYNTHETASE 703980 2% 100% 8 Search CYTIDINE+TRIPHOSPHATE+SYNTHETASE Search CYTIDINE+TRIPHOSPHATE+SYNTHETASE
6 CPEC 625758 2% 89% 8 Search CPEC Search CPEC
7 3 DEAZAURIDINE 351990 1% 100% 4 Search 3+DEAZAURIDINE Search 3+DEAZAURIDINE
8 CYTOOPHIDIA 281590 1% 80% 4 Search CYTOOPHIDIA Search CYTOOPHIDIA
9 CTPS 263992 1% 100% 3 Search CTPS Search CTPS
10 RODS AND RINGS 263992 1% 100% 3 Search RODS+AND+RINGS Search RODS+AND+RINGS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 LIU, JL , (2016) THE CYTOOPHIDIUM AND ITS KIND: FILAMENTATION AND COMPARTMENTATION OF METABOLIC ENZYMES.ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 32. VOL. 32. ISSUE . P. 349 -372 58 66% 0
2 CHANG, YF , CARMAN, GM , (2008) CTP SYNTHETASE AND ITS ROLE IN PHOSPHOLIPID SYNTHESIS IN THE YEAST SACCHAROMYCES CEREVISIAE.PROGRESS IN LIPID RESEARCH. VOL. 47. ISSUE 5. P. 333-339 56 59% 18
3 VERSCHUUR, AC , (2007) CYTIDINE TRIPHOSPHATE SYNTHETASE (CTP SYNTHETASE) AS A DRUGGABLE TARGET IN CANCER.DRUGS OF THE FUTURE. VOL. 32. ISSUE 12. P. 1071-1080 47 75% 1
4 LUNN, FA , MACDONNELL, JE , BEARNE, SL , (2008) STRUCTURAL REQUIREMENTS FOR THE ACTIVATION OF ESCHERICHIA COLI CTP SYNTHASE BY THE ALLOSTERIC EFFECTOR GTP ARE STRINGENT, BUT REQUIREMENTS FOR INHIBITION ARE LAX.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 283. ISSUE 4. P. 2010-2020 37 90% 6
5 CHANG, YF , MARTIN, SS , BALDWIN, EP , CARMAN, GM , (2007) PHOSPHORYLATION OF HUMAN CTP SYNTHETASE 1 BY PROTEIN KINASE C - IDENTIFICATION OF SER(462) AND THR(455) AS MAJOR SITES OF PHOSPHORYLATION.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 282. ISSUE 24. P. 17613 -17622 43 70% 12
6 HABRIAN, C , CHANDRASEKHARA, A , SHAHRVINI, B , HUA, B , LEE, J , JESINGHAUS, R , BARRY, R , GITAI, Z , KOLLMAN, J , BALDWIN, EP , (2016) INHIBITION OF ESCHERICHIA COLI CTP SYNTHETASE BY NADH AND OTHER NICOTINAMIDES AND THEIR MUTUAL INTERACTIONS WITH CTP AND GTP.BIOCHEMISTRY. VOL. 55. ISSUE 39. P. 5554 -5565 34 71% 0
7 CHEN, KN , ZHANG, J , TASTAN, OY , DEUSSEN, ZA , SISWICK, MYY , LIU, JL , (2011) GLUTAMINE ANALOGS PROMOTE CYTOOPHIDIUM ASSEMBLY IN HUMAN AND DROSOPHILA CELLS.JOURNAL OF GENETICS AND GENOMICS. VOL. 38. ISSUE 9. P. 391 -402 26 84% 19
8 CHOI, MG , CARMAN, GM , (2007) PHOSPHORYLATION OF HUMAN CTP SYNTHETASE 1 BY PROTEIN KINASE A - IDENTIFICATION OF THR(455) AS A MAJOR SITE OF PHOSPHORYLATION.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 282. ISSUE 8. P. 5367 -5377 39 65% 6
9 NOREE, C , MONFORT, E , SHIAU, AK , WILHELM, JE , (2014) COMMON REGULATORY CONTROL OF CTP SYNTHASE ENZYME ACTIVITY AND FILAMENT FORMATION.MOLECULAR BIOLOGY OF THE CELL. VOL. 25. ISSUE 15. P. 2282 -2290 24 77% 14
10 LUNN, FA , MACLEOD, TJ , BEARNE, SL , (2008) MUTATIONAL ANALYSIS OF CONSERVED GLYCINE RESIDUES 142, 143 AND 146 REVEALS GLY(142) IS CRITICAL FOR TETRAMERIZATION OF CTP SYNTHASE FROM ESCHERICHIA COLI.BIOCHEMICAL JOURNAL. VOL. 412. ISSUE . P. 113-121 32 73% 10

Classes with closest relation at Level 1


Rank Class id link
1 10938 TIAZOFURIN//IMPDH//BENZAMIDE RIBOSIDE
2 8448 PYRIMIDINE BIOSYNTHESIS//DIHYDROOROTASE//CARBAMOYL PHOSPHATE SYNTHETASE
3 7353 URIDINE PHOSPHORYLASE//5 PHENYLTHIOACYCLOURIDINE//LEUCOVORIN
4 22052 DCMP HYDROXYMETHYLASE//ACTIVE OXYGEN QUENCHING//ADENINE PHOSPHORIBOSYLTRANFERASE
5 24160 ODCASE//OROTIDINE 5 MONOPHOSPHATE DECARBOXYLASE//MOL DESIGN PREFORMULAT
6 14071 RUTGERS LIPID//LIPIN//LIPIN 1
7 14372 PURINE BIOSYNTHESIS//ADENYLOSUCCINATE LYASE//ADENYLOSUCCINATE LYASE DEFICIENCY
8 10382 GAMMA GLUTAMYL TRANSPEPTIDASE//GAMMA GLUTAMYLTRANSFERASE//GAMMA GLUTAMYL TRANSFERASE
9 8385 GEMCITABINE//DEOXYCYTIDINE KINASE//HENT1
10 18144 NADP MALIC ENZYME//MALIC ENZYME//OXIDATIVE DECARBOXYLASE

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