Class information for:
Level 1: PYRIMIDINE BIOSYNTHESIS//DIHYDROOROTASE//CARBAMOYL PHOSPHATE SYNTHETASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8448 1252 37.4 56%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
630 3       HEPATIC ENCEPHALOPATHY//ASYMMETRIC DIMETHYLARGININE//HYPERAMMONEMIA 13067
1445 2             HEPATIC ENCEPHALOPATHY//HYPERAMMONEMIA//MINIMAL HEPATIC ENCEPHALOPATHY 7828
8448 1                   PYRIMIDINE BIOSYNTHESIS//DIHYDROOROTASE//CARBAMOYL PHOSPHATE SYNTHETASE 1252

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PYRIMIDINE BIOSYNTHESIS authKW 395639 3% 43% 38
2 DIHYDROOROTASE authKW 380749 2% 71% 22
3 CARBAMOYL PHOSPHATE SYNTHETASE authKW 361399 3% 44% 34
4 ASPARTATE TRANSCARBAMYLASE authKW 322507 2% 58% 23
5 ASPARTATE TRANSCARBAMOYLASE authKW 250110 2% 51% 20
6 ASPARTATE CARBAMOYLTRANSFERASE authKW 228966 1% 72% 13
7 CARBAMOYLTRANSFERASE authKW 170713 1% 100% 7
8 CPS1 DEFICIENCY authKW 170713 1% 100% 7
9 CARBAMOYL PHOSPHATE authKW 159617 1% 55% 12
10 ARGININE BIOSYNTHESIS authKW 143641 1% 33% 18

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 10589 74% 0% 924
2 Biophysics 1397 13% 0% 162
3 Microbiology 869 12% 0% 153
4 Biochemical Research Methods 228 5% 0% 68
5 Genetics & Heredity 198 7% 0% 83
6 Biology 84 3% 0% 38
7 Cell Biology 48 5% 0% 67
8 Crystallography 42 2% 0% 28
9 Biotechnology & Applied Microbiology 36 4% 0% 48
10 Parasitiology 5 1% 0% 9

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ERFELIJKHEIDSLEER MICROBIOL 89780 1% 41% 9
2 BIOCHIM SIGNAUX REGULATEURS CELLULAI MOL 84093 1% 27% 13
3 UMR 7631 79739 1% 30% 11
4 DISCOVERY BIOCHEM CELL BIOL 78039 0% 80% 4
5 MERKERT CHEM 66758 4% 6% 46
6 STRUCT BASES GENOME INTEGR GRP 55740 0% 57% 4
7 CEAMER 48775 0% 100% 2
8 DYNAM EXP S EVOLUT GENOMES MICROORGANISME 48775 0% 100% 2
9 URA 1682 32516 0% 67% 2
10 GRP 739 27432 0% 38% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEMISTRY 8238 11% 0% 135
2 JOURNAL OF MOLECULAR BIOLOGY 5648 6% 0% 74
3 JOURNAL OF BIOLOGICAL CHEMISTRY 4289 13% 0% 166
4 JOURNAL OF BACTERIOLOGY 3936 6% 0% 74
5 EUROPEAN JOURNAL OF BIOCHEMISTRY 2548 4% 0% 46
6 PROTEIN SCIENCE 2201 2% 0% 24
7 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 1889 2% 0% 25
8 ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY 1670 0% 2% 3
9 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 1650 2% 0% 21
10 ADVANCES IN PHARMACOLOGY AND CHEMOTHERAPY 1353 0% 6% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PYRIMIDINE BIOSYNTHESIS 395639 3% 43% 38 Search PYRIMIDINE+BIOSYNTHESIS Search PYRIMIDINE+BIOSYNTHESIS
2 DIHYDROOROTASE 380749 2% 71% 22 Search DIHYDROOROTASE Search DIHYDROOROTASE
3 CARBAMOYL PHOSPHATE SYNTHETASE 361399 3% 44% 34 Search CARBAMOYL+PHOSPHATE+SYNTHETASE Search CARBAMOYL+PHOSPHATE+SYNTHETASE
4 ASPARTATE TRANSCARBAMYLASE 322507 2% 58% 23 Search ASPARTATE+TRANSCARBAMYLASE Search ASPARTATE+TRANSCARBAMYLASE
5 ASPARTATE TRANSCARBAMOYLASE 250110 2% 51% 20 Search ASPARTATE+TRANSCARBAMOYLASE Search ASPARTATE+TRANSCARBAMOYLASE
6 ASPARTATE CARBAMOYLTRANSFERASE 228966 1% 72% 13 Search ASPARTATE+CARBAMOYLTRANSFERASE Search ASPARTATE+CARBAMOYLTRANSFERASE
7 CARBAMOYLTRANSFERASE 170713 1% 100% 7 Search CARBAMOYLTRANSFERASE Search CARBAMOYLTRANSFERASE
8 CPS1 DEFICIENCY 170713 1% 100% 7 Search CPS1+DEFICIENCY Search CPS1+DEFICIENCY
9 CARBAMOYL PHOSPHATE 159617 1% 55% 12 Search CARBAMOYL+PHOSPHATE Search CARBAMOYL+PHOSPHATE
10 ARGININE BIOSYNTHESIS 143641 1% 33% 18 Search ARGININE+BIOSYNTHESIS Search ARGININE+BIOSYNTHESIS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 SHI, DS , ALLEWELL, NM , TUCHMAN, M , (2015) FROM GENOME TO STRUCTURE AND BACK AGAIN: A FAMILY PORTRAIT OF THE TRANSCARBAMYLASES.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 16. ISSUE 8. P. 18836 -18864 91 81% 2
2 LIPSCOMB, WN , (1994) ASPARTATE-TRANSCARBAMYLASE FROM ESCHERICHIA-COLI - ACTIVITY AND REGULATION.ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY, VOL 68. VOL. 68. ISSUE . P. 67-151 97 96% 151
3 KANTROWITZ, ER , (2012) ALLOSTERY AND COOPERATIVITY IN ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 519. ISSUE 2. P. 81 -90 52 96% 16
4 TURNBOUGH, CL , SWITZER, RL , (2008) REGULATION OF PYRIMIDINE BIOSYNTHETIC GENE EXPRESSION IN BACTERIA: REPRESSION WITHOUT REPRESSORS.MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS. VOL. 72. ISSUE 2. P. 266-300 82 55% 60
5 MARTINEZ, AI , PEREZ-ARELLANO, I , PEKKALA, S , BARCELONA, B , CERVERA, J , (2010) GENETIC, STRUCTURAL AND BIOCHEMICAL BASIS OF CARBAMOYL PHOSPHATE SYNTHETASE 1 DEFICIENCY.MOLECULAR GENETICS AND METABOLISM. VOL. 101. ISSUE 4. P. 311-323 72 64% 17
6 EVANS, DR , GUY, HI , (2002) ANALYSIS OF INTRADOMAIN SIGNALING IN THE MULTIFUNCTIONAL PROTEIN CAD USING NOVEL HYBRIDS AND CHIMERIC MOLECULES.STRUCTURES AND MECHANISMS: FROM ASHES TO ENZYMES. VOL. 827. ISSUE . P. 249 -269 60 100% 0
7 ALLEWELL, NM , (1989) ESCHERICHIA-COLI ASPARTATE TRANSCARBAMOYLASE - STRUCTURE, ENERGETICS, AND CATALYTIC AND REGULATORY MECHANISMS.ANNUAL REVIEW OF BIOPHYSICS AND BIOPHYSICAL CHEMISTRY. VOL. 18. ISSUE . P. 71-92 71 93% 65
8 SERRE, V , GUY, H , PENVERNE, B , LUX, M , ROTGERI, A , EVANS, D , HERVE, G , (1999) HALF OF SACCHAROMYCES CEREVISIAE CARBAMOYL PHOSPHATE SYNTHETASE PRODUCES AND CHANNELS CARBAMOYL PHOSPHATE TO THE FUSED ASPARTATE TRANSCARBAMOYLASE DOMAIN.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 274. ISSUE 34. P. 23794 -23801 46 96% 8
9 DIEZ-FERNANDEZ, C , MARTINEZ, AI , PEKKALA, S , BARCELONA, B , PEREZ-ARELLANO, I , GUADALAJARA, AM , SUMMAR, M , CERVERA, J , RUBIO, V , (2013) MOLECULAR CHARACTERIZATION OF CARBAMOYL-PHOSPHATE SYNTHETASE (CPS1) DEFICIENCY USING HUMAN RECOMBINANT CPS1 AS A KEY TOOL.HUMAN MUTATION. VOL. 34. ISSUE 8. P. 1149-1159 35 83% 3
10 GUY, HI , BOUVIER, A , EVANS, DR , (1997) THE SMALLEST CARBAMOYL-PHOSPHATE SYNTHETASE - A SINGLE CATALYTIC SUBDOMAIN CATALYZES ALL THREE PARTIAL REACTIONS.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 272. ISSUE 46. P. 29255-29262 50 93% 11

Classes with closest relation at Level 1


Rank Class id link
1 22069 ARGININE REPRESSOR//ARGININE REPRESSOR PROTEIN//ARGR
2 24160 ODCASE//OROTIDINE 5 MONOPHOSPHATE DECARBOXYLASE//MOL DESIGN PREFORMULAT
3 23401 CYCLOPENTENYL CYTOSINE//CTP SYNTHASE//CTP SYNTHETASE
4 34318 CIZ1//ENHANCER OF RUDIMENTARY//CW DOMAIN
5 17571 HYDANTOINASE//D HYDANTOINASE//DIHYDROPYRIMIDINASE
6 14372 PURINE BIOSYNTHESIS//ADENYLOSUCCINATE LYASE//ADENYLOSUCCINATE LYASE DEFICIENCY
7 19398 UREA SYNTHESIS//HEPATIC AMINO NITROGEN CONVERSION//N ACETYLGLUTAMATE DEGRADATION
8 15693 PHOSPHORIBOSYLTRANSFERASE//MOL PARASITOL DRUG DESIGN//PURINE SALVAGE
9 22175 HISTIDINE BIOSYNTHESIS//BETA ALPHA8 BARREL//INDOLE 3 GLYCEROL PHOSPHATE SYNTHASE
10 4786 ORNITHINE TRANSCARBAMYLASE DEFICIENCY//HYPERAMMONEMIA//UREA CYCLE DISORDERS

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