Class information for:
Level 1: PURINE BIOSYNTHESIS//ADENYLOSUCCINATE LYASE//ADENYLOSUCCINATE LYASE DEFICIENCY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14372 774 30.1 62%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
236 3       ADENOSINE//NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//ADENOSINE RECEPTORS 48331
1752 2             LESCH NYHAN SYNDROME//AMP DEAMINASE//LESCH NYHAN DISEASE 6485
14372 1                   PURINE BIOSYNTHESIS//ADENYLOSUCCINATE LYASE//ADENYLOSUCCINATE LYASE DEFICIENCY 774

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PURINE BIOSYNTHESIS authKW 791155 5% 53% 38
2 ADENYLOSUCCINATE LYASE authKW 688568 3% 73% 24
3 ADENYLOSUCCINATE LYASE DEFICIENCY authKW 554763 2% 94% 15
4 ADENYLOSUCCINATE SYNTHETASE authKW 443805 2% 75% 15
5 PURINE NUCLEOTIDE BIOSYNTHESIS authKW 262993 1% 67% 10
6 SUCCINYLADENOSINE authKW 197250 1% 100% 5
7 GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE authKW 193301 1% 70% 7
8 GART authKW 164373 1% 83% 5
9 INOSINE MONOPHOSPHATE CONTENT authKW 157800 1% 100% 4
10 ADENYLOSUCCINASE DEFICIENCY authKW 126238 1% 80% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 3907 58% 0% 451
2 Genetics & Heredity 769 14% 0% 110
3 Biophysics 537 10% 0% 81
4 Biochemical Research Methods 282 7% 0% 56
5 Microbiology 112 6% 0% 50
6 Crystallography 94 4% 0% 28
7 Medicine, Research & Experimental 61 5% 0% 35
8 Endocrinology & Metabolism 46 4% 0% 33
9 Medical Laboratory Technology 30 1% 0% 10
10 Chemistry, Medicinal 24 2% 0% 19

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOSCI PLANT PHYSIOL 52599 0% 67% 2
2 BIOCHEM 1209 W CALIF 39450 0% 100% 1
3 BIOCHEM BIOPHYS MOLEC BIOL 39450 0% 100% 1
4 CENTRUM ANALYT CHEM MOL STRUKTUR 39450 0% 100% 1
5 COMPLESSO NUOVI IST BIOL 39450 0% 100% 1
6 DEDICNCYCH METABOL PORUCH 39450 0% 100% 1
7 EXCELLENCE STRUCT BIOL BIOCOMPUTING 39450 0% 100% 1
8 HOP NECTER ENFANTS MALADES 39450 0% 100% 1
9 LEHRSTUHL BIOCH 39450 0% 100% 1
10 LIB YANTAI 39450 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADVANCES IN COMPARATIVE PHYSIOLOGY AND BIOCHEMISTRY 7888 0% 20% 1
2 BIOCHEMISTRY 4673 10% 0% 80
3 ADVANCES IN PHARMACOLOGY AND CHEMOTHERAPY 2190 0% 6% 1
4 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS 2141 2% 0% 16
5 JOURNAL OF BIOLOGICAL CHEMISTRY 2018 12% 0% 90
6 JOURNAL OF CYCLIC NUCLEOTIDE RESEARCH 1730 0% 2% 2
7 JOURNAL OF INHERITED METABOLIC DISEASE 1452 2% 0% 13
8 SCREENING 1358 0% 3% 1
9 ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS 1276 1% 0% 10
10 NUCLEOSIDES & NUCLEOTIDES 941 1% 1% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PURINE BIOSYNTHESIS 791155 5% 53% 38 Search PURINE+BIOSYNTHESIS Search PURINE+BIOSYNTHESIS
2 ADENYLOSUCCINATE LYASE 688568 3% 73% 24 Search ADENYLOSUCCINATE+LYASE Search ADENYLOSUCCINATE+LYASE
3 ADENYLOSUCCINATE LYASE DEFICIENCY 554763 2% 94% 15 Search ADENYLOSUCCINATE+LYASE+DEFICIENCY Search ADENYLOSUCCINATE+LYASE+DEFICIENCY
4 ADENYLOSUCCINATE SYNTHETASE 443805 2% 75% 15 Search ADENYLOSUCCINATE+SYNTHETASE Search ADENYLOSUCCINATE+SYNTHETASE
5 PURINE NUCLEOTIDE BIOSYNTHESIS 262993 1% 67% 10 Search PURINE+NUCLEOTIDE+BIOSYNTHESIS Search PURINE+NUCLEOTIDE+BIOSYNTHESIS
6 SUCCINYLADENOSINE 197250 1% 100% 5 Search SUCCINYLADENOSINE Search SUCCINYLADENOSINE
7 GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE 193301 1% 70% 7 Search GLYCINAMIDE+RIBONUCLEOTIDE+TRANSFORMYLASE Search GLYCINAMIDE+RIBONUCLEOTIDE+TRANSFORMYLASE
8 GART 164373 1% 83% 5 Search GART Search GART
9 INOSINE MONOPHOSPHATE CONTENT 157800 1% 100% 4 Search INOSINE+MONOPHOSPHATE+CONTENT Search INOSINE+MONOPHOSPHATE+CONTENT
10 ADENYLOSUCCINASE DEFICIENCY 126238 1% 80% 4 Search ADENYLOSUCCINASE+DEFICIENCY Search ADENYLOSUCCINASE+DEFICIENCY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 JURECKA, A , ZIKANOVA, M , KMOCH, S , TYLKI-SZYMANSKA, A , (2015) ADENYLOSUCCINATE LYASE DEFICIENCY.JOURNAL OF INHERITED METABOLIC DISEASE. VOL. 38. ISSUE 2. P. 231 -242 57 89% 3
2 ZHANG, Y , MORAR, M , EALICK, SE , (2008) STRUCTURAL BIOLOGY OF THE PURINE BIOSYNTHETIC PATHWAY.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 65. ISSUE 23. P. 3699-3724 65 77% 61
3 SPIEGEL, EK , COLMAN, RF , PATTERSON, D , (2006) ADENYLOSUCCINATE LYASE DEFICIENCY.MOLECULAR GENETICS AND METABOLISM. VOL. 89. ISSUE 1-2. P. 19-31 43 72% 42
4 JURECKA, A , ZIKANOVA, M , TYLKI-SZYMANSKA, A , KRIJT, J , BOGDANSKA, A , GRADOWSKA, W , MULLEROVA, K , SYKUT-CEGIELSKA, J , KMOCH, S , PRONICKA, E , (2008) CLINICAL, BIOCHEMICAL AND MOLECULAR FINDINGS IN SEVEN POLISH PATIENTS WITH ADENYLOSUCCINATE LYASE DEFICIENCY.MOLECULAR GENETICS AND METABOLISM. VOL. 94. ISSUE 4. P. 435 -442 27 100% 15
5 JURECKA, A , ZIKANOVA, M , JURKIEWICZ, E , TYLKI-SZYMANSKA, A , (2014) ATTENUATED ADENYLOSUCCINATE LYASE DEFICIENCY: A REPORT OF ONE CASE AND A REVIEW OF THE LITERATURE.NEUROPEDIATRICS. VOL. 45. ISSUE 1. P. 50-55 22 100% 6
6 MEHROTRA, S , BALARAM, H , (2007) KINETIC CHARACTERIZATION OF ADENYLOSUCCINATE SYNTHETASE FROM THE THERMOPHILIC ARCHAEA METHANOCALDOCOCCUS JANNASCHII.BIOCHEMISTRY. VOL. 46. ISSUE 44. P. 12821 -12832 27 96% 6
7 RAY, SP , DUVAL, N , WILKINSON, TG , SHAHEEN, SE , GHOSH, K , PATTERSON, D , (2013) INHERENT PROPERTIES OF ADENYLOSUCCINATE LYASE COULD EXPLAIN S-ADO/SAICAR RATIO DUE TO HOMOZYGOUS R426H AND R303C MUTATIONS.BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS. VOL. 1834. ISSUE 8. P. 1545 -1553 28 74% 2
8 ZIKANOVA, M , KRIJT, J , SKOPOVA, V , KRIJT, M , BARESOVA, V , KMOCH, S , (2015) SCREENING FOR ADENYLOSUCCINATE LYASE DEFICIENCY USING TANDEM MASS SPECTROMETRY ANALYSIS OF SUCCINYLPURINES IN NEONATAL DRIED BLOOD SPOTS.CLINICAL BIOCHEMISTRY. VOL. 48. ISSUE 1-2. P. 2 -7 20 91% 2
9 CIARDO, F , SALERNO, C , CURATOLO, P , (2001) NEUROLOGIC ASPECTS OF ADENYLOSUCCINATE LYASE DEFICIENCY.JOURNAL OF CHILD NEUROLOGY. VOL. 16. ISSUE 5. P. 301 -308 30 86% 24
10 ZALKIN, H , DIXON, JE , (1992) DE-NOVO PURINE NUCLEOTIDE BIOSYNTHESIS.PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY. VOL. 42. ISSUE . P. 259-287 58 51% 86

Classes with closest relation at Level 1


Rank Class id link
1 24376 PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE//NUCLEOTIDE SYNTHESIS//PRPP SYNTHETASE
2 13841 SERINE HYDROXYMETHYLTRANSFERASE//THREONINE ALDOLASE//SHMT
3 15693 PHOSPHORIBOSYLTRANSFERASE//MOL PARASITOL DRUG DESIGN//PURINE SALVAGE
4 8448 PYRIMIDINE BIOSYNTHESIS//DIHYDROOROTASE//CARBAMOYL PHOSPHATE SYNTHETASE
5 19805 PERCHLORIC ACID SOLUBLE PROTEIN//THIAMINE BINDING PROTEIN//THIAMINE BIOSYNTHESIS
6 20729 PHO85//P I TRANSPORTER//PHO84
7 2341 REDUCED FOLATE CARRIER//FOLYLPOLYGLUTAMATE SYNTHETASE//ANTIFOLATE
8 22619 ASPARAGINE SYNTHETASE//ENERGY AND SILAGE MAIZE//ENSILAGED MAIZE
9 23401 CYCLOPENTENYL CYTOSINE//CTP SYNTHASE//CTP SYNTHETASE
10 23900 ASPARTASE//MALEATE CIS TRANS ISOMERASE//MALEATE HYDRATASE

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