Class information for:
Level 1: NMD//UPF1//NONSENSE MEDIATED MRNA DECAY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
10335 1072 52.1 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
153 3       BIOCHEMISTRY & MOLECULAR BIOLOGY//RIBOSOME//RNA 62593
156 2             NUCLEAR PORE COMPLEX//PRE MRNA SPLICING//SPLICEOSOME 22915
10335 1                   NMD//UPF1//NONSENSE MEDIATED MRNA DECAY 1072

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NMD authKW 1408991 8% 57% 87
2 UPF1 authKW 1249238 5% 88% 50
3 NONSENSE MEDIATED MRNA DECAY authKW 1029645 7% 47% 77
4 EXON JUNCTION COMPLEX authKW 721331 3% 77% 33
5 NONSENSE MEDIATED DECAY authKW 470799 4% 36% 46
6 PREMATURE TERMINATION CODON authKW 469755 3% 45% 37
7 Y14 authKW 328386 1% 82% 14
8 MRNA SURVEILLANCE authKW 322057 2% 54% 21
9 EJC authKW 291654 1% 64% 16
10 EDITH JOSEPH FI ER ENZYME INHIBITORS address 280435 1% 62% 16

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 6227 39% 0% 421
2 Biochemistry & Molecular Biology 5475 59% 0% 628
3 Genetics & Heredity 2011 19% 0% 203
4 Developmental Biology 538 5% 0% 52
5 Biophysics 196 6% 0% 64
6 Medicine, Research & Experimental 165 6% 0% 62
7 Biotechnology & Applied Microbiology 36 4% 0% 43
8 Mycology 30 1% 0% 9
9 Biology 27 2% 0% 23
10 Plant Sciences 25 4% 0% 41

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EDITH JOSEPH FI ER ENZYME INHIBITORS 280435 1% 62% 16
2 MOL MED PARTNERSHIP UNIT 147685 2% 23% 23
3 PEDIAT ONCOL HEMATOL IMMUNOL 79136 3% 10% 28
4 EXPT THER EUT INTERDISCIPLINARY ONCOL 56966 0% 100% 2
5 UMR8197 46 56966 0% 100% 2
6 GREGORY FLEMING JAMES CYST FIBROSIS 40035 1% 9% 16
7 UMR IMAGING BRAIN 37976 0% 67% 2
8 MED MOLEC GENET MICROBIOL 32359 0% 23% 5
9 MICROBIOL MOL BIODEF 32040 0% 38% 3
10 BEADLE E146 28483 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RNA-A PUBLICATION OF THE RNA SOCIETY 16284 3% 2% 27
2 RNA 15333 3% 1% 37
3 NATURE STRUCTURAL & MOLECULAR BIOLOGY 8200 2% 1% 25
4 GENES & DEVELOPMENT 5480 4% 1% 38
5 MOLECULAR CELL 4975 3% 1% 31
6 MOLECULAR AND CELLULAR BIOLOGY 4092 5% 0% 57
7 WILEY INTERDISCIPLINARY REVIEWS-RNA 3789 1% 2% 7
8 EMBO JOURNAL 2108 3% 0% 36
9 NUCLEIC ACIDS RESEARCH 2107 5% 0% 55
10 BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS 1725 1% 1% 8

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NMD 1408991 8% 57% 87 Search NMD Search NMD
2 UPF1 1249238 5% 88% 50 Search UPF1 Search UPF1
3 NONSENSE MEDIATED MRNA DECAY 1029645 7% 47% 77 Search NONSENSE+MEDIATED+MRNA+DECAY Search NONSENSE+MEDIATED+MRNA+DECAY
4 EXON JUNCTION COMPLEX 721331 3% 77% 33 Search EXON+JUNCTION+COMPLEX Search EXON+JUNCTION+COMPLEX
5 NONSENSE MEDIATED DECAY 470799 4% 36% 46 Search NONSENSE+MEDIATED+DECAY Search NONSENSE+MEDIATED+DECAY
6 PREMATURE TERMINATION CODON 469755 3% 45% 37 Search PREMATURE+TERMINATION+CODON Search PREMATURE+TERMINATION+CODON
7 Y14 328386 1% 82% 14 Search Y14 Search Y14
8 MRNA SURVEILLANCE 322057 2% 54% 21 Search MRNA+SURVEILLANCE Search MRNA+SURVEILLANCE
9 EJC 291654 1% 64% 16 Search EJC Search EJC
10 NONSENSE MUTATIONS 273042 2% 46% 21 Search NONSENSE+MUTATIONS Search NONSENSE+MUTATIONS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 HUG, N , LONGMAN, D , CACERES, JF , (2016) MECHANISM AND REGULATION OF THE NONSENSE-MEDIATED DECAY PATHWAY.NUCLEIC ACIDS RESEARCH. VOL. 44. ISSUE 4. P. 1483 -1495 135 84% 13
2 HE, F , JACOBSON, A , (2015) NONSENSE-MEDIATED MRNA DECAY: DEGRADATION OF DEFECTIVE TRANSCRIPTS IS ONLY PART OF THE STORY.ANNUAL REVIEW OF GENETICS, VOL 49. VOL. 49. ISSUE . P. 339 -366 187 81% 13
3 KERVESTIN, S , JACOBSON, A , (2012) NMD: A MULTIFACETED RESPONSE TO PREMATURE TRANSLATIONAL TERMINATION.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 13. ISSUE 11. P. 700 -712 139 78% 218
4 KUROSAKI, T , MAQUAT, LE , (2016) NONSENSE-MEDIATED MRNA DECAY IN HUMANS AT A GLANCE.JOURNAL OF CELL SCIENCE. VOL. 129. ISSUE 3. P. 461 -467 118 91% 9
5 CHANG, YF , IMAM, JS , WILKINSON, ME , (2007) THE NONSENSE-MEDIATED DECAY RNA SURVEILLANCE PATHWAY.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 76. ISSUE . P. 51-74 130 81% 613
6 SCHWEINGRUBER, C , RUFENER, SC , ZUND, D , YAMASHITA, A , MUHLEMANN, O , (2013) NONSENSE-MEDIATED MRNA DECAY - MECHANISMS OF SUBSTRATE MRNA RECOGNITION AND DEGRADATION IN MAMMALIAN CELLS.BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS. VOL. 1829. ISSUE 6-7. P. 612-623 129 73% 126
7 KAROUSIS, ED , NASIF, S , MUHLEMANN, O , (2016) NONSENSE-MEDIATED MRNA DECAY: NOVEL MECHANISTIC INSIGHTS AND BIOLOGICAL IMPACT.WILEY INTERDISCIPLINARY REVIEWS-RNA. VOL. 7. ISSUE 5. P. 661 -682 146 84% 2
8 LYKKE-ANDERSEN, S , JENSEN, TH , (2015) NONSENSE-MEDIATED MRNA DECAY: AN INTRICATE MACHINERY THAT SHAPES TRANSCRIPTOMES.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 16. ISSUE 11. P. 665 -677 110 79% 43
9 LE HIR, H , SAULIERE, J , WANG, Z , (2016) THE EXON JUNCTION COMPLEX AS A NODE OF POST-TRANSCRIPTIONAL NETWORKS.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 17. ISSUE 1. P. - 120 67% 11
10 ISKEN, O , MAQUAT, LE , (2007) QUALITY CONTROL OF EUKARYOTIC MRNA: SAFEGUARDING CELLS FROM ABNORMAL MRNA FUNCTION.GENES & DEVELOPMENT. VOL. 21. ISSUE 15. P. 1833 -1856 155 63% 341

Classes with closest relation at Level 1


Rank Class id link
1 16463 MRNA EXPORT//NXF1//THO COMPLEX
2 6198 P BODIES//STRESS GRANULES//DECAPPING
3 17891 RRP6//MRNP BIOGENESIS METAB//DIS3
4 6806 TRANSLATION TERMINATION//RELEASE FACTOR//FRAMESHIFT
5 28145 INTRON MEDIATED ENHANCEMENT//INTRON//IME
6 14173 RIBOSOME PROFILING//UORF//UPSTREAM OPEN READING FRAME
7 785 SR PROTEINS//ALTERNATIVE SPLICING//POLYPYRIMIDINE TRACT BINDING PROTEIN
8 12218 RNA HELICASE//DEAD BOX PROTEIN//DEAD BOX
9 18779 TMRNA//TRANS TRANSLATION//SMPB
10 17872 EXON SKIPPING//MC LOCKWOOD MUSCULAR DYSTROPHY//NEUROMUSCULAR ALS

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