Class information for:
Level 2: ANGIOTENSIN II//RENIN ANGIOTENSIN SYSTEM//ANGIOTENSIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
85 27105 37.1 72%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
57 3       ANGIOTENSIN II//HYPERTENSION//PERIPHERAL VASCULAR DISEASES 89232
85 2             ANGIOTENSIN II//RENIN ANGIOTENSIN SYSTEM//ANGIOTENSIN 27105
857 1                   SODIUM APPETITE//SUBFORNICAL ORGAN//THIRST 3002
1245 1                   CAS 89396 94 1//TA 6366//IMIDAPRIL 2764
1401 1                   ANGIOTENSINOGEN//ANGIOTENSIN CONVERTING ENZYME//ANGIOTENSIN CONVERTING ENZYME GENE 2679
2699 1                   AT2 RECEPTOR//ANGIOTENSIN II RECEPTOR//ANGIOTENSIN RECEPTORS 2169
3425 1                   PRORENIN//RENIN//JUXTAGLOMERULAR CELLS 1986
4516 1                   CANDESARTAN CILEXETIL//ANGIOTENSIN II RECEPTOR ANTAGONIST//LOSARTAN 1774
6313 1                   ANGIOTENSIN 1 7//ANGIOTENSIN CONVERTING ENZYME 2//MAS RECEPTOR 1501
8798 1                   ANGIOTENSIN CONVERTING ENZYME//ANGIOTENSIN I CONVERTING ENZYME//CD143 1215
9376 1                   ALISKIREN//PRORENIN RECEPTOR//DIRECT RENIN INHIBITOR 1161
10106 1                   ANGIOTENSINOGEN//ADRENAL RENIN//HIGH MOLECULAR WEIGHT ANGIOTENSINOGEN 1091
11902 1                   ANGIOTENSIN II//VASC RENAL PATHOL//ARTERIAL ANTIGEN 946
11979 1                   TELMISARTAN//AZILSARTAN//AZILSARTAN MEDOXOMIL 940
12504 1                   ANGIOTENSIN IV//AT4 RECEPTOR//INSULIN REGULATED AMINOPEPTIDASE 901
14427 1                   ZOFENOPRIL//RAMIPRILAT//CAPTOPRIL 770
15547 1                   HYPERTENS RENAL EXCELLENCE//URINARY ANGIOTENSINOGEN//RENAL EXCELLENCE 706
15903 1                   RENIN INHIBITOR//KETOPIPERAZINE//REMIKIREN 684
17384 1                   INHIBITORS OF ANGIOTENSINOGEN CONVERTING ENZYME//ACE ID//AGTR1 GENE 602
20530 1                   CANDESARTAN//MALIGNANT STROKE PRONE SPONTANEOUSLY HYPERTENSIVE RAT//INTRAMURAL PROGRAMS 456
21720 1                   TOAC//CHIRAL NITROXIDES//SPIN LABELLED AMINO ACIDS 408
26050 1                   UNITE PHYSIOL INTEGREE//PITHED SHR//PREJUNCTIONAL INTERACTION 264
28636 1                   COLD INDUCED HYPERTENSION//AT1 RECEPTOR ANTISENSE//HYPERTENSION 2K1C 202
29435 1                   TGRMREN227//ENOS KNOCK OUT MICE//TRANSGENIC RATS TGR 186
29713 1                   OCULAR RENIN ANGIOTENSIN SYSTEM//REN 2 RAT//S PHARMACOL MOL BIOL 181
29762 1                   GONDA GOLD MIED VASC SURG//ATHEROSCLERSSIS//BARE METAL STENT IMPLANTATION 180
30346 1                   AT1A MRNA//ABCB4 KNOCKOUT//ANGIOTENSIN ANG 1 7 170
30542 1                   ESCOLA PROF LUIZ C ELO//ANGIOTENSIN II TYPE IA RECEPTOR//ANGIOTENSIN II TYPE IA RECEPTOR ANTAGONIST 167

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 ANGIOTENSIN II authKW 814436 9% 31% 2384
2 RENIN ANGIOTENSIN SYSTEM authKW 797176 6% 43% 1636
3 ANGIOTENSIN authKW 520886 4% 39% 1205
4 ANGIOTENSINOGEN authKW 484056 2% 72% 599
5 ANGIOTENSIN CONVERTING ENZYME authKW 448507 4% 39% 1025
6 ANGIOTENSIN 1 7 authKW 443337 2% 87% 455
7 RENIN authKW 333403 3% 36% 824
8 LOSARTAN authKW 299479 3% 38% 712
9 AT2 RECEPTOR authKW 244665 1% 83% 261
10 JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM journal 224428 2% 48% 419

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Peripheral Vascular Diseases 111875 19% 2% 5222
2 Pharmacology & Pharmacy 31490 22% 1% 5878
3 Physiology 30950 12% 1% 3363
4 Cardiac & Cardiovascular System 18105 11% 1% 3053
5 Endocrinology & Metabolism 8949 8% 1% 2212
6 Urology & Nephrology 7684 6% 1% 1525
7 Medicine, Research & Experimental 5067 6% 0% 1692
8 Neurosciences 2465 8% 0% 2220
9 Chemistry, Medicinal 1537 3% 0% 818
10 Biochemistry & Molecular Biology 852 10% 0% 2623

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HYPERTENS VASC DIS 55644 0% 48% 103
2 MOL CARDIOVASC BIOL PHARMACOL 41383 0% 60% 61
3 HYPERTENS RENAL EXCELLENCE 35707 0% 52% 61
4 HYPERTENS VASC 35147 0% 24% 131
5 RENAL EXCELLENCE 21166 0% 61% 31
6 PHYSIOL FUNCT GENOM 20041 0% 16% 115
7 PHYSIOL PATHOL 19202 0% 17% 102
8 U36 17913 0% 29% 56
9 CURRICULUM TEACHING MEMORY 17345 0% 86% 18
10 RECEPTOR SIGNAL TRANSDUCT 16555 0% 82% 18

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM 224428 2% 48% 419
2 HYPERTENSION 164435 5% 11% 1300
3 JOURNAL OF HYPERTENSION 85273 3% 9% 861
4 CLINICAL AND EXPERIMENTAL HYPERTENSION PART A-THEORY AND PRACTICE 72537 1% 22% 298
5 AMERICAN JOURNAL OF HYPERTENSION 34120 2% 7% 427
6 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 33896 2% 5% 583
7 JOURNAL OF HUMAN HYPERTENSION 20660 1% 7% 262
8 HYPERTENSION RESEARCH 19303 1% 8% 208
9 CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 17449 1% 5% 297
10 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 16294 1% 4% 361

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 ANGIOTENSIN II 814436 9% 31% 2384 Search ANGIOTENSIN+II Search ANGIOTENSIN+II
2 RENIN ANGIOTENSIN SYSTEM 797176 6% 43% 1636 Search RENIN+ANGIOTENSIN+SYSTEM Search RENIN+ANGIOTENSIN+SYSTEM
3 ANGIOTENSIN 520886 4% 39% 1205 Search ANGIOTENSIN Search ANGIOTENSIN
4 ANGIOTENSINOGEN 484056 2% 72% 599 Search ANGIOTENSINOGEN Search ANGIOTENSINOGEN
5 ANGIOTENSIN CONVERTING ENZYME 448507 4% 39% 1025 Search ANGIOTENSIN+CONVERTING+ENZYME Search ANGIOTENSIN+CONVERTING+ENZYME
6 ANGIOTENSIN 1 7 443337 2% 87% 455 Search ANGIOTENSIN+1+7 Search ANGIOTENSIN+1+7
7 RENIN 333403 3% 36% 824 Search RENIN Search RENIN
8 LOSARTAN 299479 3% 38% 712 Search LOSARTAN Search LOSARTAN
9 AT2 RECEPTOR 244665 1% 83% 261 Search AT2+RECEPTOR Search AT2+RECEPTOR
10 PRORENIN 213475 1% 88% 217 Search PRORENIN Search PRORENIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 PAUL, M , MEHR, AP , KREUTZ, R , (2006) PHYSIOLOGY OF LOCAL RENIN-ANGIOTENSIN SYSTEMS.PHYSIOLOGICAL REVIEWS. VOL. 86. ISSUE 3. P. 747 -803 514 71% 689
2 DE GASPARO, M , CATT, KJ , INAGAMI, T , WRIGHT, JW , UNGER, T , (2000) INTERNATIONAL UNION OF PHARMACOLOGY. XXIII. THE ANGIOTENSIN II RECEPTORS.PHARMACOLOGICAL REVIEWS. VOL. 52. ISSUE 3. P. 415 -472 469 74% 1316
3 KARNIK, SS , UNAL, H , KEMP, JR , TIRUPULA, KC , EGUCHI, S , VANDERHEYDEN, PML , THOMAS, WG , (2015) INTERNATIONAL UNION OF BASIC AND CLINICAL PHARMACOLOGY. XCIX. ANGIOTENSIN RECEPTORS: INTERPRETERS OF PATHOPHYSIOLOGICAL ANGIOTENSINERGIC STIMULI.PHARMACOLOGICAL REVIEWS. VOL. 67. ISSUE 4. P. 754 -819 632 62% 11
4 JONES, ES , VINH, A , MCCARTHY, CA , GASPARI, TA , WIDDOP, RE , (2008) AT(2) RECEPTORS: FUNCTIONAL RELEVANCE IN CARDIOVASCULAR DISEASE.PHARMACOLOGY & THERAPEUTICS. VOL. 120. ISSUE 3. P. 292 -316 343 81% 112
5 MICHEL, MC , FOSTER, C , BRUNNER, HR , LIU, LS , (2013) A SYSTEMATIC COMPARISON OF THE PROPERTIES OF CLINICALLY USED ANGIOTENSIN II TYPE 1 RECEPTOR ANTAGONISTS.PHARMACOLOGICAL REVIEWS. VOL. 65. ISSUE 2. P. 809-848 320 70% 64
6 SANTOS, RAS , FERREIRA, AJ , VERANO-BRAGA, T , BADER, M , (2013) ANGIOTENSIN-CONVERTING ENZYME 2, ANGIOTENSIN-(1-7) AND MAS: NEW PLAYERS OF THE RENIN-ANGIOTENSIN SYSTEM.JOURNAL OF ENDOCRINOLOGY. VOL. 216. ISSUE 2. P. R1-R17 191 96% 108
7 SAAVEDRA, JM , (1992) BRAIN AND PITUITARY ANGIOTENSIN.ENDOCRINE REVIEWS. VOL. 13. ISSUE 2. P. 329-380 475 78% 336
8 MICHEL, MC , BRUNNER, HR , FOSTER, C , HUO, Y , (2016) ANGIOTENSIN II TYPE 1 RECEPTOR ANTAGONISTS IN ANIMAL MODELS OF VASCULAR, CARDIAC, METABOLIC AND RENAL DISEASE.PHARMACOLOGY & THERAPEUTICS. VOL. 164. ISSUE . P. 1 -81 496 47% 1
9 JIANG, F , YANG, JM , ZHANG, YT , DONG, M , WANG, SX , ZHANG, Q , LIU, FF , ZHANG, K , ZHANG, C , (2014) ANGIOTENSIN-CONVERTING ENZYME 2 AND ANGIOTENSIN 1-7: NOVEL THERAPEUTIC TARGETS.NATURE REVIEWS CARDIOLOGY. VOL. 11. ISSUE 7. P. 413 -426 196 96% 33
10 NAIK, P , MURUMKAR, P , GIRIDHAR, R , YADAV, MR , (2010) ANGIOTENSIN II RECEPTOR TYPE 1 (AT(1)) SELECTIVE NONPEPTIDIC ANTAGONISTS-A PERSPECTIVE.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 18. ISSUE 24. P. 8418 -8456 235 91% 39

Classes with closest relation at Level 2


Rank Class id link
1 2253 RENAL DENERVATION//RESISTANT HYPERTENSION//RENAL SYMPATHETIC DENERVATION
2 1343 ROSTRAL VENTROLATERAL MEDULLA//CAUDAL VENTROLATERAL MEDULLA//BARORECEPTORS
3 3090 HEREDITARY ANGIOEDEMA//C1 INHIBITOR//ANGIOEDEMA
4 1619 BRADYKININ//KININS//FACTOR XII
5 938 CARDIAC HYPERTROPHY//HYPERTROPHY//CARDIOTROPHIN 1
6 3903 KIKUCHI FUJIMOTO DISEASE//HISTIOCYTIC NECROTIZING LYMPHADENITIS//KIKUCHIS DISEASE
7 2418 HYDROCHLOROTHIAZIDE//CICLETANINE//TORASEMIDE
8 1330 SODIUM LITHIUM COUNTERTRANSPORT//SODIUM//SALT SENSITIVITY
9 524 MICROALBUMINURIA//CYSTATIN C//GLOMERULAR FILTRATION RATE
10 197 ENDOTHELIUM//NITRIC OXIDE//NADPH OXIDASE

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