Class information for:
Level 2: BRADYKININ//KININS//FACTOR XII

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1619 7044 35.3 66%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
315 3       ALLERGY//MAST CELLS//BRADYKININ 39886
1619 2             BRADYKININ//KININS//FACTOR XII 7044
881 1                   BRADYKININ//KININS//B 2 RECEPTOR 2991
3705 1                   FACTOR XII//FACTOR XI//FACTOR XI DEFICIENCY 1927
5927 1                   KALLISTATIN//KALLIKREIN//TISSUE KALLIKREIN 1557
25729 1                   ACTIVATION OF CARBOXYLIC GROUP//AMINONAPHTHALENESULFONAMIDES//FLUOROMETRIC ENZYME ASSAY 274
33820 1                   HUMAN URINARY KALLIDINOGENASE SK 827//1 5 BRADYKININ//353 TRIIODOTHYRONINE CLINICAL STUDIES RESPONSE TO GLUCOSE INGESTION 119
35066 1                   HOTEL DIEU HEMATOL//PYRUVIC AND LACTIC ACIDS//ELECTRODE ADSORPTION 102
36741 1                   TRANSMEMBRANE CA2 GRADIENT//STIMULATORY GTP BINDING PROTEIN//STIMULATORY GTP BINDING PROTEIN GS 74

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 BRADYKININ authKW 1333906 14% 31% 1000
2 KININS authKW 554543 3% 52% 244
3 FACTOR XII authKW 448727 2% 66% 158
4 KININOGEN authKW 416704 2% 58% 165
5 KALLIKREIN KININ SYSTEM authKW 381928 2% 64% 138
6 FACTOR XI authKW 366360 2% 69% 122
7 KALLIKREIN authKW 361721 4% 33% 252
8 B 2 RECEPTOR authKW 352551 2% 75% 109
9 BRADYKININ RECEPTOR authKW 345882 2% 63% 127
10 BRADYKININ B 2 RECEPTOR authKW 343943 2% 71% 112

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Peripheral Vascular Diseases 12505 13% 0% 910
2 Hematology 11231 13% 0% 901
3 Pharmacology & Pharmacy 9307 23% 0% 1615
4 Biochemistry & Molecular Biology 3918 23% 0% 1622
5 Physiology 1869 7% 0% 462
6 Medicine, Research & Experimental 1289 6% 0% 436
7 Endocrinology & Metabolism 724 5% 0% 364
8 Immunology 662 7% 0% 460
9 Biophysics 497 4% 0% 294
10 Chemistry, Medicinal 346 3% 0% 202

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SOL SHERRY THROMBOSIS 136450 2% 28% 113
2 GRP PHARMACOCHIM RECEPTEURS 23588 0% 78% 7
3 U388 21697 0% 26% 19
4 MOL BIOL PEPTIDE HORMONES GRP 17332 0% 100% 4
5 UROL CHIYODA KU 17332 0% 100% 4
6 AMALIA BIRON THROMBOSIS HEMOSTASIS 17128 0% 23% 17
7 KENT HAEMOPHILIA 16036 0% 37% 10
8 GRP PEPTIDE BIOCHEM 13864 0% 80% 4
9 RECH RHUMATOL IMMUNOL 13464 0% 10% 31
10 HYPERTENS ATHEROSCLEROSIS SECT 12981 0% 25% 12

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IMMUNOPHARMACOLOGY 86404 2% 12% 163
2 HYPERTENSION 12100 3% 2% 181
3 BRITISH JOURNAL OF PHARMACOLOGY 12053 3% 1% 225
4 BIOLOGICAL CHEMISTRY 11072 1% 3% 91
5 THROMBOSIS RESEARCH 10064 2% 2% 156
6 THROMBOSIS AND HAEMOSTASIS 7252 2% 1% 131
7 BLOOD COAGULATION & FIBRINOLYSIS 5465 1% 2% 65
8 INTERNATIONAL IMMUNOPHARMACOLOGY 4933 1% 2% 71
9 EUROPEAN JOURNAL OF PHARMACOLOGY 4552 3% 1% 177
10 JOURNAL OF THROMBOSIS AND HAEMOSTASIS 4288 1% 2% 63

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 BRADYKININ 1333906 14% 31% 1000 Search BRADYKININ Search BRADYKININ
2 KININS 554543 3% 52% 244 Search KININS Search KININS
3 FACTOR XII 448727 2% 66% 158 Search FACTOR+XII Search FACTOR+XII
4 KININOGEN 416704 2% 58% 165 Search KININOGEN Search KININOGEN
5 KALLIKREIN KININ SYSTEM 381928 2% 64% 138 Search KALLIKREIN+KININ+SYSTEM Search KALLIKREIN+KININ+SYSTEM
6 FACTOR XI 366360 2% 69% 122 Search FACTOR+XI Search FACTOR+XI
7 KALLIKREIN 361721 4% 33% 252 Search KALLIKREIN Search KALLIKREIN
8 B 2 RECEPTOR 352551 2% 75% 109 Search B+2+RECEPTOR Search B+2+RECEPTOR
9 BRADYKININ RECEPTOR 345882 2% 63% 127 Search BRADYKININ+RECEPTOR Search BRADYKININ+RECEPTOR
10 BRADYKININ B 2 RECEPTOR 343943 2% 71% 112 Search BRADYKININ+B+2+RECEPTOR Search BRADYKININ+B+2+RECEPTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LEEB-LUNDBERG, LMF , MARCEAU, F , MULLER-ESTERL, W , PETTIBONE, DJ , ZURAW, BL , (2005) INTERNATIONAL UNION OF PHARMACOLOGY. XLV. CLASSIFICATION OF THE KININ RECEPTOR FAMILY: FROM MOLECULAR MECHANISMS TO PATHOPHYSIOLOGICAL CONSEQUENCES.PHARMACOLOGICAL REVIEWS. VOL. 57. ISSUE 1. P. 27-77 384 76% 515
2 BHOOLA, KD , FIGUEROA, CD , WORTHY, K , (1992) BIOREGULATION OF KININS - KALLIKREINS, KININOGENS, AND KININASES.PHARMACOLOGICAL REVIEWS. VOL. 44. ISSUE 1. P. 1-80 422 71% 1497
3 COUTURE, R , BLAES, N , GIROLAMI, JP , (2014) KININ RECEPTORS IN VASCULAR BIOLOGY AND PATHOLOGY.CURRENT VASCULAR PHARMACOLOGY. VOL. 12. ISSUE 2. P. 223 -248 250 70% 14
4 FARKAS, S , ELES, J , (2011) THE THERAPEUTIC POTENTIAL OF BRADYKININ B-1 RECEPTOR ANTAGONISTS IN CHRONIC PAIN.DRUGS OF THE FUTURE. VOL. 36. ISSUE 4. P. 301-319 189 91% 2
5 MARCEAU, F , HESS, JF , BACHVAROV, DR , (1998) THE B-1 RECEPTORS FOR KININS.PHARMACOLOGICAL REVIEWS. VOL. 50. ISSUE 3. P. 357 -386 172 81% 437
6 COLMAN, RW , SCHMAIER, AH , (1997) CONTACT SYSTEM: A VASCULAR BIOLOGY MODULATOR WITH ANTICOAGULANT, PROFIBRINOLYTIC, ANTIADHESIVE, AND PROINFLAMMATORY ATTRIBUTES.BLOOD. VOL. 90. ISSUE 10. P. 3819 -3843 186 81% 325
7 CALIXTO, JB , MEDEIROS, R , FERNANDES, ES , FERREIRA, J , CABRINI, DA , CAMPOS, MM , (2004) KININ B-1 RECEPTORS: KEY G-PROTEIN-COUPLED RECEPTORS AND THEIR ROLE IN INFLAMMATORY AND PAINFUL PROCESSES.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 143. ISSUE 7. P. 803-818 133 82% 152
8 HALL, JM , (1992) BRADYKININ RECEPTORS - PHARMACOLOGICAL PROPERTIES AND BIOLOGICAL ROLES.PHARMACOLOGY & THERAPEUTICS. VOL. 56. ISSUE 2. P. 131-190 185 71% 397
9 JOSEPH, K , KAPLAN, AP , (2005) FORMATION OF BRADYKININ: A MAJOR CONTRIBUTOR TO THE INNATE INFLAMMATORY RESPONSE.ADVANCES IN IMMUNOLOGY, VOL 86. VOL. 86. ISSUE . P. 159 -208 140 80% 82
10 HE, R , CHEN, D , HE, SL , (2012) FACTOR XI: HEMOSTASIS, THROMBOSIS, AND ANTITHROMBOSIS.THROMBOSIS RESEARCH. VOL. 129. ISSUE 5. P. 541-550 117 83% 17

Classes with closest relation at Level 2


Rank Class id link
1 3090 HEREDITARY ANGIOEDEMA//C1 INHIBITOR//ANGIOEDEMA
2 3458 MASPIN//TAFI//THROMBIN ACTIVATABLE FIBRINOLYSIS INHIBITOR
3 85 ANGIOTENSIN II//RENIN ANGIOTENSIN SYSTEM//ANGIOTENSIN
4 637 TISSUE FACTOR//THROMBOMODULIN//PROTEIN C
5 1415 DIPEPTIDYL PEPTIDASE IV//CD26//AMINOPEPTIDASE
6 4096 HISTIDINE RICH GLYCOPROTEIN//HRG//SODIUM TETRAHYDROBORATE
7 1744 CATHEPSIN//CATHEPSIN K//CATHEPSIN B
8 2253 RENAL DENERVATION//RESISTANT HYPERTENSION//RENAL SYMPATHETIC DENERVATION
9 2517 PROTEASE ACTIVATED RECEPTOR//THROMBIN//THROMBIN RECEPTOR
10 3536 EVOLUTIONARY IMMUNOBIOL//PERITONEAL INFLAMMATION//ZYMOSAN

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