Class information for:
Level 1: CANDESARTAN CILEXETIL//ANGIOTENSIN II RECEPTOR ANTAGONIST//LOSARTAN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
4516 1774 31.7 72%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
57 3       ANGIOTENSIN II//HYPERTENSION//PERIPHERAL VASCULAR DISEASES 89232
85 2             ANGIOTENSIN II//RENIN ANGIOTENSIN SYSTEM//ANGIOTENSIN 27105
4516 1                   CANDESARTAN CILEXETIL//ANGIOTENSIN II RECEPTOR ANTAGONIST//LOSARTAN 1774

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANDESARTAN CILEXETIL authKW 665009 5% 47% 82
2 ANGIOTENSIN II RECEPTOR ANTAGONIST authKW 612670 7% 29% 122
3 LOSARTAN authKW 395726 12% 11% 209
4 FIMASARTAN authKW 352553 1% 79% 26
5 ANGIOTENSIN II ANTAGONIST authKW 339384 3% 35% 56
6 IRBESARTAN authKW 333890 5% 22% 87
7 EPROSARTAN authKW 312883 2% 45% 40
8 VALSARTAN authKW 185072 5% 12% 89
9 AT1 RECEPTOR ANTAGONIST authKW 149646 2% 24% 36
10 ANGIOTENSIN II RECEPTOR BLOCKER authKW 148948 4% 12% 71

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 9585 43% 0% 768
2 Peripheral Vascular Diseases 8543 21% 0% 368
3 Chemistry, Medicinal 4141 15% 0% 263
4 Cardiac & Cardiovascular System 1055 11% 0% 190
5 Chemistry, Organic 751 11% 0% 191
6 Medicine, General & Internal 185 6% 0% 114
7 Toxicology 85 3% 0% 51
8 Medicine, Research & Experimental 76 4% 0% 65
9 Urology & Nephrology 21 2% 0% 32
10 Primary Health Care 10 0% 0% 6

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SMITHKLINE BEECHAM CLIN PHARMACOL UNIT 68836 0% 50% 8
2 HYPERTENS VASC MED 63508 1% 15% 24
3 KOTOBUKI S 38723 0% 75% 3
4 BIOORGAN SCI 5 34422 0% 100% 2
5 PATHOPHYSIOL MED TEACHING 34422 0% 100% 2
6 OKLAHOMA CARDIOVASC HYPERTENS 25029 0% 36% 4
7 CARDIOL HYPERTENS UNIT 22947 0% 67% 2
8 STARNBERG HOSP 21506 0% 25% 5
9 ASAN SCI CARDIOL 17211 0% 100% 1
10 BIOCOCCA S GERARDO HOSP 17211 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF HUMAN HYPERTENSION 24978 4% 2% 73
2 BLOOD PRESSURE 24244 2% 4% 37
3 AMERICAN JOURNAL OF HYPERTENSION 14219 4% 1% 70
4 JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM 13201 1% 3% 26
5 CLINICAL THERAPEUTICS 8967 3% 1% 51
6 JOURNAL OF HYPERTENSION 7915 4% 1% 67
7 CLINICAL DRUG INVESTIGATION 7530 2% 1% 31
8 CARDIOVASCULAR DRUG REVIEWS 6900 1% 3% 13
9 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 6732 4% 1% 66
10 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 6182 5% 0% 96

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CANDESARTAN CILEXETIL 665009 5% 47% 82 Search CANDESARTAN+CILEXETIL Search CANDESARTAN+CILEXETIL
2 ANGIOTENSIN II RECEPTOR ANTAGONIST 612670 7% 29% 122 Search ANGIOTENSIN+II+RECEPTOR+ANTAGONIST Search ANGIOTENSIN+II+RECEPTOR+ANTAGONIST
3 LOSARTAN 395726 12% 11% 209 Search LOSARTAN Search LOSARTAN
4 FIMASARTAN 352553 1% 79% 26 Search FIMASARTAN Search FIMASARTAN
5 ANGIOTENSIN II ANTAGONIST 339384 3% 35% 56 Search ANGIOTENSIN+II+ANTAGONIST Search ANGIOTENSIN+II+ANTAGONIST
6 IRBESARTAN 333890 5% 22% 87 Search IRBESARTAN Search IRBESARTAN
7 EPROSARTAN 312883 2% 45% 40 Search EPROSARTAN Search EPROSARTAN
8 VALSARTAN 185072 5% 12% 89 Search VALSARTAN Search VALSARTAN
9 AT1 RECEPTOR ANTAGONIST 149646 2% 24% 36 Search AT1+RECEPTOR+ANTAGONIST Search AT1+RECEPTOR+ANTAGONIST
10 ANGIOTENSIN II RECEPTOR BLOCKER 148948 4% 12% 71 Search ANGIOTENSIN+II+RECEPTOR+BLOCKER Search ANGIOTENSIN+II+RECEPTOR+BLOCKER

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 NAIK, P , MURUMKAR, P , GIRIDHAR, R , YADAV, MR , (2010) ANGIOTENSIN II RECEPTOR TYPE 1 (AT(1)) SELECTIVE NONPEPTIDIC ANTAGONISTS-A PERSPECTIVE.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 18. ISSUE 24. P. 8418 -8456 193 75% 39
2 MICHEL, MC , FOSTER, C , BRUNNER, HR , LIU, LS , (2013) A SYSTEMATIC COMPARISON OF THE PROPERTIES OF CLINICALLY USED ANGIOTENSIN II TYPE 1 RECEPTOR ANTAGONISTS.PHARMACOLOGICAL REVIEWS. VOL. 65. ISSUE 2. P. 809-848 191 42% 64
3 WEXLER, RR , GREENLEE, WJ , IRVIN, JD , GOLDBERG, MR , PRENDERGAST, K , SMITH, RD , TIMMERMANS, PBMWM , (1996) NONPEPTIDE ANGIOTENSIN II RECEPTOR ANTAGONISTS: THE NEXT GENERATION IN ANTIHYPERTENSIVE THERAPY.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 39. ISSUE 3. P. 625 -656 139 70% 242
4 ISRAILI, ZH , (2000) CLINICAL PHARMACOKINETICS OF ANGIOTENSIN II (AT(1)) RECEPTOR BLOCKERS IN HYPERTENSION.JOURNAL OF HUMAN HYPERTENSION. VOL. 14. ISSUE . P. S73 -S86 79 78% 126
5 DINA, R , JAFARI, M , (2000) ANGIOTENSIN II-RECEPTOR ANTAGONISTS: AN OVERVIEW.AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY. VOL. 57. ISSUE 13. P. 1231 -1241 58 87% 38
6 YANG, RR , LUO, ZQ , LIU, Y , SUN, M , ZHENG, L , CHEN, YY , LI, YP , WANG, H , CHEN, LZ , WU, M , ET AL (2016) DRUG INTERACTIONS WITH ANGIOTENSIN RECEPTOR BLOCKERS: ROLE OF HUMAN CYTOCHROMES P450.CURRENT DRUG METABOLISM. VOL. 17. ISSUE 7. P. 681 -691 54 63% 0
7 CONLIN, PR , SPENCE, JD , WILLIAMS, B , RIBEIRO, AB , SAITO, I , BENEDICT, C , BUNT, AMG , (2000) ANGIOTENSIN II ANTAGONISTS FOR HYPERTENSION: ARE THERE DIFFERENCES IN EFFICACY?.AMERICAN JOURNAL OF HYPERTENSION. VOL. 13. ISSUE 4. P. 418 -426 42 91% 108
8 SICA, DA , GEHR, TWB , GHOSH, S , (2005) CLINICAL PHARMACOKINETICS OF LOSARTAN.CLINICAL PHARMACOKINETICS. VOL. 44. ISSUE 8. P. 797-814 59 59% 54
9 CSAJKA, C , BUCLIN, T , BRUNNER, HR , BIOLLAZ, J , (1997) PHARMACOKINETIC-PHARMACODYNAMIC PROFILE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS.CLINICAL PHARMACOKINETICS. VOL. 32. ISSUE 1. P. 1-29 56 78% 58
10 HERAN, BS , WONG, MMY , HERAN, IK , WRIGHT, JM , (2008) BLOOD PRESSURE LOWERING EFFICACY OF ANGIOTENSIN RECEPTOR BLOCKERS FOR PRIMARY HYPERTENSION.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 4. P. - 43 69% 23

Classes with closest relation at Level 1


Rank Class id link
1 26050 UNITE PHYSIOL INTEGREE//PITHED SHR//PREJUNCTIONAL INTERACTION
2 25829 COUGH//24 HOUR MONITORING OF ARTERIAL PRESSURE//ACE II INHIBITOR
3 2699 AT2 RECEPTOR//ANGIOTENSIN II RECEPTOR//ANGIOTENSIN RECEPTORS
4 21720 TOAC//CHIRAL NITROXIDES//SPIN LABELLED AMINO ACIDS
5 7760 HYDROCHLOROTHIAZIDE//AMLODIPINE BESYLATE//LOSARTAN POTASSIUM
6 11979 TELMISARTAN//AZILSARTAN//AZILSARTAN MEDOXOMIL
7 4584 PROTEINURIA//ANGIOTENSIN RECEPTOR BLOCKER//DUAL BLOCKADE
8 61 HYPERTENSION//ISOLATED SYSTOLIC HYPERTENSION//BLOOD PRESSURE CONTROL
9 15903 RENIN INHIBITOR//KETOPIPERAZINE//REMIKIREN
10 26108 BIOCHEM TECHNOL SCI TECHNOL//GPR35//RESONANT WAVEGUIDE GRATING BIOSENSOR

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