Class information for:
Level 2: ENDOTHELIUM//NITRIC OXIDE//NADPH OXIDASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
197 21389 42.1 82%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
57 3       ANGIOTENSIN II//HYPERTENSION//PERIPHERAL VASCULAR DISEASES 89232
197 2             ENDOTHELIUM//NITRIC OXIDE//NADPH OXIDASE 21389
2397 1                   NADPH OXIDASE//NOX4//NOX1 2259
3828 1                   ENDOTHELIUM DERIVED RELAXING FACTOR//EDRF//N G NITRO L ARGININE 1899
4046 1                   FLOW MEDIATED DILATION//ENDOTHELIAL FUNCTION//FLOW MEDIATED DILATATION 1857
4550 1                   VASCULAR HYPERTROPHY//SPONTANEOUSLY HYPERTENSIVE RATS//SMALL ARTERIES 1767
4694 1                   ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR//EDHF//ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR EDHF 1742
4838 1                   NORMAL PATHOL PHYSIOL//NITRIC OXIDE//L NAME 1717
7582 1                   L ARGININE//HYPERCHOLESTEROLEMIA//REGENERATED ENDOTHELIUM 1351
8162 1                   EXERCISE HYPEREMIA//MUSCLE BLOOD FLOW//HUMAN CARDIOVASC PHYSIOL 1285
9930 1                   PHYSIOL MORPHOL//RAT AORTAE//DIABETES 1106
10907 1                   NUTRITIVE FLOW//NON NUTRITIVE FLOW//INSULIN TRANSPORT 1026
11184 1                   NOS3//ENOS GENE//ENDOTHELIAL NITRIC OXIDE SYNTHASE 1002
12971 1                   MYOGENIC RESPONSE//MYOGENIC TONE//MICROVASC BIOL GRP 868
17432 1                   LOCAL BLOOD FLOW CONTROL//CAPILLARY RAREFACTION//HYPERTENSION VOLUME DEPENDENT 599
18382 1                   HUMAN FOREARM VASCULATURE//CGP 48369//ENDOTHELIUM 554
19372 1                   DALTON CARDIOVASC//DIABET CARDIOVASC BIOL PROGRAM//DIABET CARDIOVASC HLTH 508
20328 1                   REYNOLDS OKLAHOMA AGING//VASCULAR AGING//DONALD W REYNOLDS GERIATR MED 466
20641 1                   MOL CARDIOBIOL PROGRAM//CARDIOVASC HYPERTENS//ENDOTHELIAL NITRIC OXIDE SYNTHASE 451
20881 1                   ENDOTHELIUM DEPENDENT CONTRACTION//ENDOTHELIUM DERIVED CONTRACTING FACTOR//THROMBOXANE PROSTANOID RECEPTOR 442
25295 1                   ENDOTHELIAL RESPONSES//POSTJUNCTIONAL ALPHA ADRENOCEPTORS//AD TAT MEMBRANO MECHANISMS 285
28494 1                   RODENT MODELS OF OBESITY//RODENT MODELS OF METABOLIC SYNDROME//REGULATION OF SKELETAL MUSCLE BLOOD FLOW 205

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 ENDOTHELIUM authKW 490608 10% 16% 2188
2 NITRIC OXIDE authKW 319340 14% 8% 3023
3 NADPH OXIDASE authKW 278775 4% 24% 822
4 ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR authKW 242069 1% 62% 275
5 ENDOTHELIUM DERIVED RELAXING FACTOR authKW 209413 2% 40% 368
6 ENDOTHELIAL FUNCTION authKW 188690 3% 21% 646
7 PERIPHERAL VASCULAR DISEASES WoSSC 184655 27% 2% 5881
8 EDHF authKW 156582 1% 62% 177
9 VASODILATION authKW 145694 2% 20% 510
10 FLOW MEDIATED DILATION authKW 135222 1% 42% 224

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Peripheral Vascular Diseases 184655 27% 2% 5881
2 Physiology 88926 23% 1% 4847
3 Cardiac & Cardiovascular System 63475 22% 1% 4736
4 Pharmacology & Pharmacy 15812 18% 0% 3830
5 Endocrinology & Metabolism 5059 7% 0% 1523
6 Hematology 4309 5% 0% 1095
7 Sport Sciences 3649 4% 0% 756
8 Medicine, Research & Experimental 2929 6% 0% 1183
9 Urology & Nephrology 1504 3% 0% 687
10 Cell Biology 622 5% 0% 1061

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 PHYSIOL MORPHOL 78486 0% 61% 90
2 NORMAL PATHOL PHYSIOL 38274 0% 26% 105
3 DALTON CARDIOVASC 34398 1% 16% 153
4 KARDIOVASKULARE PHYSIOL 29380 0% 44% 47
5 PHYSIOL 27666 8% 1% 1705
6 MED PHARMACOL PHYSIOL 26599 1% 15% 128
7 HUMAN VASC CONTROL 22810 0% 100% 16
8 HUMAN CARDIOVASC PHYSIOL 21990 0% 86% 18
9 HYPERTENS VASC 21000 0% 16% 90
10 ROCKIES FDN 17208 0% 93% 13

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HYPERTENSION 109728 4% 8% 944
2 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 103337 4% 8% 953
3 MICROCIRCULATION 44890 1% 17% 184
4 JOURNAL OF HYPERTENSION 43888 3% 6% 550
5 JOURNAL OF VASCULAR RESEARCH 42498 1% 16% 190
6 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 30029 2% 4% 487
7 BRITISH JOURNAL OF PHARMACOLOGY 28951 3% 3% 609
8 BLOOD VESSELS 26773 0% 22% 87
9 CIRCULATION RESEARCH 24524 2% 4% 422
10 MICROVASCULAR RESEARCH 19515 1% 7% 192

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 ENDOTHELIUM 490608 10% 16% 2188 Search ENDOTHELIUM Search ENDOTHELIUM
2 NITRIC OXIDE 319340 14% 8% 3023 Search NITRIC+OXIDE Search NITRIC+OXIDE
3 NADPH OXIDASE 278775 4% 24% 822 Search NADPH+OXIDASE Search NADPH+OXIDASE
4 ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR 242069 1% 62% 275 Search ENDOTHELIUM+DERIVED+HYPERPOLARIZING+FACTOR Search ENDOTHELIUM+DERIVED+HYPERPOLARIZING+FACTOR
5 ENDOTHELIUM DERIVED RELAXING FACTOR 209413 2% 40% 368 Search ENDOTHELIUM+DERIVED+RELAXING+FACTOR Search ENDOTHELIUM+DERIVED+RELAXING+FACTOR
6 ENDOTHELIAL FUNCTION 188690 3% 21% 646 Search ENDOTHELIAL+FUNCTION Search ENDOTHELIAL+FUNCTION
7 EDHF 156582 1% 62% 177 Search EDHF Search EDHF
8 VASODILATION 145694 2% 20% 510 Search VASODILATION Search VASODILATION
9 FLOW MEDIATED DILATION 135222 1% 42% 224 Search FLOW+MEDIATED+DILATION Search FLOW+MEDIATED+DILATION
10 ENDOTHELIAL DYSFUNCTION 125585 3% 15% 588 Search ENDOTHELIAL+DYSFUNCTION Search ENDOTHELIAL+DYSFUNCTION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 VANHOUTTE, PM , SHIMOKAWA, H , FELETOU, M , TANG, EHC , (2017) ENDOTHELIAL DYSFUNCTION AND VASCULAR DISEASE - A 30TH ANNIVERSARY UPDATE.ACTA PHYSIOLOGICA. VOL. 219. ISSUE 1. P. 22 -96 318 33% 6
2 LASSEGUE, B , SAN MARTIN, A , GRIENDLING, KK , (2012) BIOCHEMISTRY, PHYSIOLOGY, AND PATHOPHYSIOLOGY OF NADPH OXIDASES IN THE CARDIOVASCULAR SYSTEM.CIRCULATION RESEARCH. VOL. 110. ISSUE 10. P. 1364 -1390 255 68% 250
3 GARLAND, CJ , DORA, KA , (2017) EDH: ENDOTHELIUM-DEPENDENT HYPERPOLARIZATION AND MICROVASCULAR SIGNALLING.ACTA PHYSIOLOGICA. VOL. 219. ISSUE 1. P. 152 -161 68 91% 7
4 BEDARD, K , KRAUSE, KH , (2007) THE NOX FAMILY OF ROS-GENERATING NADPH OXIDASES: PHYSIOLOGY AND PATHOPHYSIOLOGY.PHYSIOLOGICAL REVIEWS. VOL. 87. ISSUE 1. P. 245-313 253 28% 2431
5 VANHOUTTE, PM , SHIMOKAWA, H , TANG, EHC , FELETOU, M , (2009) ENDOTHELIAL DYSFUNCTION AND VASCULAR DISEASE.ACTA PHYSIOLOGICA. VOL. 196. ISSUE 2. P. 193 -222 211 51% 327
6 JOYNER, MJ , CASEY, DP , (2015) REGULATION OF INCREASED BLOOD FLOW (HYPEREMIA) TO MUSCLES DURING EXERCISE: A HIERARCHY OF COMPETING PHYSIOLOGICAL NEEDS.PHYSIOLOGICAL REVIEWS. VOL. 95. ISSUE 2. P. 549 -601 211 56% 18
7 KONIOR, A , SCHRAMM, A , CZESNIKIEWICZ-GUZIK, M , GUZIK, TJ , (2014) NADPH OXIDASES IN VASCULAR PATHOLOGY.ANTIOXIDANTS & REDOX SIGNALING. VOL. 20. ISSUE 17. P. 2794 -2814 143 69% 66
8 BROWN, DI , GRIENDLING, KK , (2009) NOX PROTEINS IN SIGNAL TRANSDUCTION.FREE RADICAL BIOLOGY AND MEDICINE. VOL. 47. ISSUE 9. P. 1239 -1253 136 68% 359
9 DRUMMOND, GR , SELEMIDIS, S , GRIENDLING, KK , SOBEY, CG , (2011) COMBATING OXIDATIVE STRESS IN VASCULAR DISEASE: NADPH OXIDASES AS THERAPEUTIC TARGETS.NATURE REVIEWS DRUG DISCOVERY. VOL. 10. ISSUE 6. P. 453 -471 131 60% 306
10 BRANDES, RP , WEISSMANN, N , SCHRODER, K , (2010) NADPH OXIDASES IN CARDIOVASCULAR DISEASE.FREE RADICAL BIOLOGY AND MEDICINE. VOL. 49. ISSUE 5. P. 687 -706 192 57% 110

Classes with closest relation at Level 2


Rank Class id link
1 2253 RENAL DENERVATION//RESISTANT HYPERTENSION//RENAL SYMPATHETIC DENERVATION
2 1933 SKIN BLOOD FLOW//SYMPATHETIC SKIN RESPONSE//EXERCISE PRESSOR REFLEX
3 295 NITRIC OXIDE//PEROXYNITRITE//NITRIC OXIDE-BIOLOGY AND CHEMISTRY
4 1243 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY//JOURNAL OF AUTONOMIC PHARMACOLOGY//BLOOD VESSELS
5 1078 ENDOTHELIN//ENDOTHELIN 1//ENDOTHELIN RECEPTORS
6 1804 ARTERIOGENESIS//COLLATERAL CIRCULATION//TRANSMYOCARDIAL LASER REVASCULARIZATION
7 1336 WALL SHEAR STRESS//SHEAR STRESS//JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
8 2078 ASYMMETRIC DIMETHYLARGININE//ARGINASE//ADMA
9 2821 NITRATE TOLERANCE//NITROGLYCERIN//ORGANIC NITRATES
10 2756 ANGIOGENESIS GRP//RSR13//OXYGEN TRANSPORT

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