Class information for:
Level 2: TGF BETA//SMAD//ENDOGLIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1072 9938 45.9 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
27 3       DEVELOPMENTAL BIOLOGY//DEVELOPMENT//AGR2 109777
1072 2             TGF BETA//SMAD//ENDOGLIN 9938
1117 1                   SMAD//SMAD4//TGF BETA 2843
1881 1                   TGF BETA RECEPTORS//TRANSFORMING GROWTH FACTOR BETA//TGF BETA 2445
12726 1                   BONE MORPHOGENETIC PROTEIN 9//BMP9//BONE MORPHOGENETIC PROTEIN 885
14371 1                   ENDOGLIN//CD105//TRC105 774
19200 1                   LTBP//ALPHA V BETA 6//INTEGRIN ALPHA V BETA 6 517
20430 1                   PROXIMAL SYMPHALANGISM//SYMPHALANGISM//NOG 461
20882 1                   TGFB1//T869C//TGFBR1 442
21816 1                   GFAP GENE PROMOTER//TGF BETA 1 TRANSGENIC MICE//PHENOTYPE INDUCTION 404
22102 1                   GREMLIN//GREMLIN 1//CRIM1 393
24524 1                   ADVENTITIAL FIBROBLASTS//CAROTID ARTERY RESTENOSIS//ADVENTITIA 309
29076 1                   MIIP//BETAGLYCAN//T BETA RIII 193
30129 1                   SERINE THREONINE KINASE RECEPTORS//ACTIVIN RECEPTOR 1//ACTR 1 174
35392 1                   RED FISIOPATOL ENFERMEDADES HEPAT//ANTI APOPTOTIC SIGNALLING//BIOQUIM BIOL MOL MIXTO 98

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 TGF BETA authKW 540319 10% 17% 1009
2 SMAD authKW 365134 4% 31% 381
3 ENDOGLIN authKW 327675 2% 51% 210
4 TRANSFORMING GROWTH FACTOR BETA authKW 290731 6% 16% 603
5 TGF BETA RECEPTORS authKW 190761 1% 53% 118
6 SMAD4 authKW 168319 2% 36% 152
7 TGF BETA 1 authKW 150081 4% 14% 355
8 SMAD7 authKW 138921 1% 40% 112
9 CD105 authKW 126363 1% 44% 93
10 CELL REGULAT CARCINOGENESIS address 105427 1% 32% 107

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Cell Biology 21160 25% 0% 2455
2 Oncology 18028 23% 0% 2321
3 Biochemistry & Molecular Biology 8618 27% 0% 2721
4 Developmental Biology 2833 4% 0% 373
5 Genetics & Heredity 2329 8% 0% 768
6 Medicine, Research & Experimental 1152 5% 0% 516
7 Pathology 1102 4% 0% 365
8 Immunology 723 6% 0% 596
9 Biophysics 651 4% 0% 404
10 Hematology 412 3% 0% 279

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL REGULAT CARCINOGENESIS 105427 1% 32% 107
2 DEV SIGNALLING 61635 0% 57% 35
3 FUTURE PROGRAM 47155 0% 59% 26
4 AFFILIATED ZHONGNAN HOSP 28823 0% 72% 13
5 LEHRSTUHL PHYSIOL CHEM 2 24661 0% 54% 15
6 STEM CELL BIOL THER Y 23809 0% 52% 15
7 NEWCASTLE BOWEL CANC ABORAT 18424 0% 100% 6
8 CLIN DIAGNOST MED 17759 0% 64% 9
9 CHEMOPREVENT 17224 0% 18% 32
10 AFFILIATED SOUTHWEST HOSP 17050 0% 56% 10

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYTOKINE & GROWTH FACTOR REVIEWS 12805 1% 7% 58
2 CANCER RESEARCH 6483 3% 1% 297
3 GROWTH FACTORS 6423 0% 5% 41
4 JOURNAL OF CELLULAR PHYSIOLOGY 6358 1% 1% 147
5 ONCOGENE 5704 2% 1% 188
6 JOURNAL OF BIOLOGICAL CHEMISTRY 5308 6% 0% 549
7 CELL GROWTH & DIFFERENTIATION 4336 0% 3% 45
8 JOURNAL OF CELLULAR BIOCHEMISTRY 2172 1% 1% 82
9 EXPERIMENTAL CELL RESEARCH 2011 1% 1% 95
10 CELLULAR SIGNALLING 1671 1% 1% 50

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 TGF BETA 540319 10% 17% 1009 Search TGF+BETA Search TGF+BETA
2 SMAD 365134 4% 31% 381 Search SMAD Search SMAD
3 ENDOGLIN 327675 2% 51% 210 Search ENDOGLIN Search ENDOGLIN
4 TRANSFORMING GROWTH FACTOR BETA 290731 6% 16% 603 Search TRANSFORMING+GROWTH+FACTOR+BETA Search TRANSFORMING+GROWTH+FACTOR+BETA
5 TGF BETA RECEPTORS 190761 1% 53% 118 Search TGF+BETA+RECEPTORS Search TGF+BETA+RECEPTORS
6 SMAD4 168319 2% 36% 152 Search SMAD4 Search SMAD4
7 TGF BETA 1 150081 4% 14% 355 Search TGF+BETA+1 Search TGF+BETA+1
8 SMAD7 138921 1% 40% 112 Search SMAD7 Search SMAD7
9 CD105 126363 1% 44% 93 Search CD105 Search CD105
10 SMADS 104060 1% 36% 95 Search SMADS Search SMADS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 PARDALI, K , MOUSTAKAS, A , (2007) ACTIONS OF TGF-BETA AS TUMOR SUPPRESSOR AND PRO-METASTATIC FACTOR IN HUMAN CANCER.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1775. ISSUE 1. P. 21-62 296 64% 315
2 SHI, YG , MASSAGUE, J , (2003) MECHANISMS OF TGF-BETA SIGNALING FROM CELL MEMBRANE TO THE NUCLEUS.CELL. VOL. 113. ISSUE 6. P. 685 -700 107 80% 3115
3 DERYNCK, R , AKHURST, RJ , BALMAIN, A , (2001) TGF-BETA SIGNALING IN TUMOR SUPPRESSION AND CANCER PROGRESSION.NATURE GENETICS. VOL. 29. ISSUE 2. P. 117 -129 190 63% 1386
4 MASSAGUE, J , (1998) TGF-BETA SIGNAL TRANSDUCTION.ANNUAL REVIEW OF BIOCHEMISTRY. VOL. 67. ISSUE . P. 753 -791 155 55% 3145
5 FENG, XH , DERYNCK, R , (2005) SPECIFICITY AND VERSATILITY IN TGF-BETA SIGNALING THROUGH SMADS.ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY. VOL. 21. ISSUE . P. 659 -693 134 69% 1005
6 MASSAGUE, J , SEOANE, J , WOTTON, D , (2005) SMAD TRANSCRIPTION FACTORS.GENES & DEVELOPMENT. VOL. 19. ISSUE 23. P. 2783-2810 144 58% 1281
7 BERNABEU, C , LOPEZ-NOVOA, JM , QUINTANILLA, M , (2009) THE EMERGING ROLE OF TGF-BETA SUPERFAMILY CORECEPTORS IN CANCER.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. VOL. 1792. ISSUE 10. P. 954 -973 188 70% 103
8 KUBICZKOVA, L , SEDLARIKOVA, L , HAJEK, R , SEVCIKOVA, S , (2012) TGF-BETA - AN EXCELLENT SERVANT BUT A BAD MASTER.JOURNAL OF TRANSLATIONAL MEDICINE. VOL. 10. ISSUE . P. - 179 67% 59
9 LIU, F , (2003) RECEPTOR-REGULATED SMADS IN TGF-BETA SIGNALING.FRONTIERS IN BIOSCIENCE-LANDMARK. VOL. 8. ISSUE . P. S1280-S1303 207 79% 27
10 BROWN, KA , PIETENPOL, JA , MOSES, HL , (2007) A TALE OF TWO PROTEINS: DIFFERENTIAL ROLES AND REGULATION OF SMAD2 AND SMAD3 IN TGF-BETA SIGNALING.JOURNAL OF CELLULAR BIOCHEMISTRY. VOL. 101. ISSUE 1. P. 9-33 149 74% 183

Classes with closest relation at Level 2


Rank Class id link
1 2641 EPITHELIAL MESENCHYMAL TRANSITION//EMT//SNAIL
2 3126 PERIOSTIN//CONNECTIVE TISSUE GROWTH FACTOR//CTGF
3 3713 A20//LAPTM4B//WWP1
4 1648 EPIDERMAL GROWTH FACTOR//HB EGF//TRANSFORMING GROWTH FACTOR ALPHA
5 256 PLATELET RICH PLASMA//BONE REGENERATION//GUIDED TISSUE REGENERATION
6 1310 HEPATIC STELLATE CELLS//LIVER FIBROSIS//LIVER REGENERATION
7 2544 HEREDITARY HEMORRHAGIC TELANGIECTASIA//PULMONARY ARTERIOVENOUS MALFORMATION//HEMOPTYSIS
8 3175 ID 1//NRSF//ID1
9 2107 LYMPHANGIOGENESIS//VEGF C//PODOPLANIN
10 3037 KLF4//KRUPPEL LIKE FACTOR//GADD45

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