Class information for:
Level 2: RESTRICTION ENDONUCLEASE//BIOTECHNIQUES//RESTRICTION MODIFICATION SYSTEM

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1609 7100 27.9 71%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
33 3       JOURNAL OF BACTERIOLOGY//MICROBIOLOGY//MOLECULAR MICROBIOLOGY 107033
1609 2             RESTRICTION ENDONUCLEASE//BIOTECHNIQUES//RESTRICTION MODIFICATION SYSTEM 7100
784 1                   RESTRICTION ENDONUCLEASE//RESTRICTION MODIFICATION SYSTEM//RESTRICTION MODIFICATION 3079
12652 1                   PLASMID PURIFICATION//PLASMID DNA//SUPERCOILED PLASMID DNA 891
12753 1                   T VECTOR//TA CLONING//GENE SYNTHESIS 883
15387 1                   MEGAPRIMER//MULTIPLE SITE DIRECTED MUTAGENESIS//OVERLAP EXTENSION 715
21162 1                   NOTI LINKING CLONES//NOTI LINKING AND JUMPING CLONES//NOTL LINKING CLONES 430
21956 1                   GENOME WALKING//FALSE POSITIVE EXCLUSION//UNKNOWN FLANKING SEQUENCES 399
22511 1                   GC RICH DNA//HOT START//AU GOLD NANOPARTICLES 379
33383 1                   SPEL 6//AND PLASMIDS//ASSEMBLY OF DNA FRAGMENTS 125
35141 1                   CALLIGONUM COMOSUM//CALLIGONUM//CALLIGONUM SPECIES 102
35472 1                   ANALYTICAL PITFALLS//ARTEFACTUAL RESULTS OF LABORATORY TESTS//AUTOMATED BLOOD COUNTERS 97

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 RESTRICTION ENDONUCLEASE authKW 274358 2% 39% 163
2 BIOTECHNIQUES journal 251022 8% 10% 595
3 RESTRICTION MODIFICATION SYSTEM authKW 217896 1% 65% 78
4 RESTRICTION MODIFICATION authKW 201451 1% 63% 75
5 NUCLEIC ACIDS RESEARCH journal 140170 16% 3% 1135
6 DNA PROT INTERACT UNIT address 91321 1% 51% 42
7 ISOSCHIZOMER authKW 89526 0% 77% 27
8 PLASMID PURIFICATION authKW 80017 0% 85% 22
9 RESTRICTION ENZYME authKW 73626 1% 28% 61
10 PLASMID DNA authKW 71672 2% 13% 129

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Biochemistry & Molecular Biology 43539 64% 0% 4520
2 Biochemical Research Methods 25234 20% 0% 1447
3 Genetics & Heredity 6831 14% 0% 995
4 Biotechnology & Applied Microbiology 5495 13% 0% 922
5 Microbiology 1166 7% 0% 481
6 Chemistry, Analytical 981 7% 0% 464
7 Biophysics 709 5% 0% 336
8 Cell Biology 206 5% 0% 352
9 Biology 25 1% 0% 91
10 Virology 2 1% 0% 48

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DNA PROT INTERACT UNIT 91321 1% 51% 42
2 BIOINFORMAT PROT ENGN 28408 0% 19% 35
3 NIPPONKO KU 21494 0% 100% 5
4 PROGRAM BIOPHYS BIOCHEM 20013 0% 27% 17
5 CICS UBI INVEST CIENCIAS SAUDE 19954 0% 39% 12
6 BIOPHYS S 19615 0% 24% 19
7 KEY HORMONE DEV 17910 0% 83% 5
8 ABT BIOPHYS BIOCHEM VERFAHREN 13755 0% 80% 4
9 IBBS BIOPHYS S 13430 0% 63% 5
10 ABT STRUKTURANAL 12896 0% 100% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 BIOTECHNIQUES 251022 8% 10% 595
2 NUCLEIC ACIDS RESEARCH 140170 16% 3% 1135
3 GENE 54410 7% 3% 497
4 PCR-METHODS AND APPLICATIONS 17676 0% 16% 26
5 ANALYTICAL BIOCHEMISTRY 16019 4% 1% 265
6 GENE ANALYSIS TECHNIQUES 14330 0% 19% 18
7 MOLECULAR BIOTECHNOLOGY 12263 1% 4% 73
8 MOLECULAR BIOLOGY 11112 2% 2% 111
9 JOURNAL OF MOLECULAR BIOLOGY 7364 3% 1% 204
10 ACS SYNTHETIC BIOLOGY 5998 0% 5% 28

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RESTRICTION ENDONUCLEASE 274358 2% 39% 163 Search RESTRICTION+ENDONUCLEASE Search RESTRICTION+ENDONUCLEASE
2 RESTRICTION MODIFICATION SYSTEM 217896 1% 65% 78 Search RESTRICTION+MODIFICATION+SYSTEM Search RESTRICTION+MODIFICATION+SYSTEM
3 RESTRICTION MODIFICATION 201451 1% 63% 75 Search RESTRICTION+MODIFICATION Search RESTRICTION+MODIFICATION
4 ISOSCHIZOMER 89526 0% 77% 27 Search ISOSCHIZOMER Search ISOSCHIZOMER
5 PLASMID PURIFICATION 80017 0% 85% 22 Search PLASMID+PURIFICATION Search PLASMID+PURIFICATION
6 RESTRICTION ENZYME 73626 1% 28% 61 Search RESTRICTION+ENZYME Search RESTRICTION+ENZYME
7 PLASMID DNA 71672 2% 13% 129 Search PLASMID+DNA Search PLASMID+DNA
8 DNA METHYLTRANSFERASE 65625 1% 14% 106 Search DNA+METHYLTRANSFERASE Search DNA+METHYLTRANSFERASE
9 SITE SPECIFIC ENDONUCLEASE 61400 0% 71% 20 Search SITE+SPECIFIC+ENDONUCLEASE Search SITE+SPECIFIC+ENDONUCLEASE
10 T VECTOR 59153 0% 81% 17 Search T+VECTOR Search T+VECTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 PINGOUD, A , WILSON, GG , WENDE, W , (2014) TYPE II RESTRICTION ENDONUCLEASES-A HISTORICAL PERSPECTIVE AND MORE.NUCLEIC ACIDS RESEARCH. VOL. 42. ISSUE 12. P. 7489 -7527 306 82% 26
2 LOENEN, WAM , DRYDEN, DTF , RALEIGH, EA , WILSON, GG , (2014) TYPE I RESTRICTION ENZYMES AND THEIR RELATIVES.NUCLEIC ACIDS RESEARCH. VOL. 42. ISSUE 1. P. 20 -44 167 83% 31
3 MCCLELLAND, M , NELSON, M , RASCHKE, E , (1994) EFFECT OF SITE-SPECIFIC MODIFICATION ON RESTRICTION ENDONUCLEASES AND DNA MODIFICATION METHYLTRANSFERASES.NUCLEIC ACIDS RESEARCH. VOL. 22. ISSUE 17. P. 3640-3659 270 84% 276
4 KESSLER, C , MANTA, V , (1990) SPECIFICITY OF RESTRICTION ENDONUCLEASES AND DNA MODIFICATION METHYLTRANSFERASES - A REVIEW.GENE. VOL. 92. ISSUE 1-2. P. 1-248 382 82% 112
5 MADHUSOODANAN, UK , RAO, DN , (2010) DIVERSITY OF DNA METHYLTRANSFERASES THAT RECOGNIZE ASYMMETRIC TARGET SEQUENCES.CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 45. ISSUE 2. P. 125 -145 155 90% 11
6 NELSON, M , RASCHKE, E , MCCLELLAND, M , (1993) EFFECT OF SITE-SPECIFIC METHYLATION ON RESTRICTION ENDONUCLEASES AND DNA MODIFICATION METHYLTRANSFERASES.NUCLEIC ACIDS RESEARCH. VOL. 21. ISSUE 13. P. 3139-3154 246 84% 62
7 PINGOUD, A , FUXREITER, M , PINGOUD, V , WENDE, W , (2005) TYPE II RESTRICTION ENDONUCLEASES: STRUCTURE AND MECHANISM.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 62. ISSUE 6. P. 685-707 141 74% 275
8 LOENEN, WAM , DRYDEN, DTF , RALEIGH, EA , WILSON, GG , MURRAY, NE , (2014) HIGHLIGHTS OF THE DNA CUTTERS: A SHORT HISTORY OF THE RESTRICTION ENZYMES.NUCLEIC ACIDS RESEARCH. VOL. 42. ISSUE 1. P. 3 -19 121 70% 39
9 PINGOUD, A , JELTSCH, A , (2001) STRUCTURE AND FUNCTION OF TYPE II RESTRICTION ENDONUCLEASES.NUCLEIC ACIDS RESEARCH. VOL. 29. ISSUE 18. P. 3705-3727 135 77% 357
10 RAO, DN , SAHA, S , KRISHNAMURTHY, V , (2000) ATP-DEPENDENT RESTRICTION ENZYMES.PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY, VOL 64. VOL. 64. ISSUE . P. 1 -63 168 88% 27

Classes with closest relation at Level 2


Rank Class id link
1 3063 DNA TRANSPOSITION//PHAGE MU//TRANSPOSASE
2 3958 COMPUTER APPLICATIONS IN THE BIOSCIENCES//ADAPTIVE WEIGHTED LEAST SQUARES//AMBIGRAM
3 3655 RESIDUAL DNA//AFFINITY RESINS//NONSPECIFIC BINDING PROTEINS
4 2924 SAGE//SERIAL ANALYSIS OF GENE EXPRESSION//DIFFERENTIAL DISPLAY
5 2350 BACILLUS SUBTILIS//SPORULATION//JOURNAL OF BACTERIOLOGY
6 371 RNA POLYMERASE//HFQ//JOURNAL OF BACTERIOLOGY
7 160 WERNER SYNDROME//DNA POLYMERASE//DNA REPAIR
8 959 BACTERIOPHAGE//PHAGE THERAPY//ENDOLYSIN
9 1714 MOLECULAR BEACON//MUTATION DETECTION//SEQUENCING BY HYBRIDIZATION
10 1115 GENOME EDITING//CRISPR CAS9//CRISPR

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