Class information for:
Level 1: PLASMID PURIFICATION//PLASMID DNA//SUPERCOILED PLASMID DNA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12652 891 24.9 67%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
33 3       JOURNAL OF BACTERIOLOGY//MICROBIOLOGY//MOLECULAR MICROBIOLOGY 107033
1609 2             RESTRICTION ENDONUCLEASE//BIOTECHNIQUES//RESTRICTION MODIFICATION SYSTEM 7100
12652 1                   PLASMID PURIFICATION//PLASMID DNA//SUPERCOILED PLASMID DNA 891

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PLASMID PURIFICATION authKW 581254 2% 81% 21
2 PLASMID DNA authKW 564068 14% 13% 128
3 SUPERCOILED PLASMID DNA authKW 461730 2% 84% 16
4 ALKALINE LYSIS authKW 231649 1% 52% 13
5 PLASMID DNA PURIFICATION authKW 213519 1% 69% 9
6 PDNA VACCINES authKW 171347 1% 100% 5
7 PLASMID DNA PRODUCTION authKW 171347 1% 100% 5
8 CICS UBI INVEST CIENCIAS SAUDE address 159172 1% 39% 12
9 PRE MIR 29 authKW 137078 0% 100% 4
10 SMALL DNA LIGANDS authKW 137078 0% 100% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemical Research Methods 9650 35% 0% 310
2 Biotechnology & Applied Microbiology 4584 31% 0% 275
3 Chemistry, Analytical 3115 26% 0% 232
4 Biochemistry & Molecular Biology 1722 38% 0% 340
5 Engineering, Chemical 232 8% 0% 72
6 Genetics & Heredity 147 7% 0% 60
7 Medicine, Research & Experimental 55 4% 0% 37
8 Food Science & Technology 26 3% 0% 28
9 Pharmacology & Pharmacy 24 6% 0% 52
10 Polymer Science 10 3% 0% 23

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CICS UBI INVEST CIENCIAS SAUDE 159172 1% 39% 12
2 INVEST CIENCIAS SAUDE 92497 2% 15% 18
3 CICS 79561 3% 9% 26
4 ADV BIOCHEM ENGN 70918 3% 7% 31
5 AGROMICROBIAL OURCES PLICAT MOA 68539 0% 100% 2
6 BIOPHARMACEUT PROD DEV US 68539 0% 100% 2
7 PROC DEV UK 68539 0% 100% 2
8 VIRAL IMMUNOTHER EUT IMMUNOTHER EUT 68539 0% 100% 2
9 ENGN BIOL QUIM 67845 3% 6% 31
10 CHAIR FERMENTAT ENGN 60919 0% 44% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOTECHNIQUES 62378 12% 2% 105
2 BIOPHARM INTERNATIONAL 11048 1% 2% 13
3 ANALYTICAL BIOCHEMISTRY 9060 8% 0% 70
4 GENE ANALYSIS TECHNIQUES 8823 1% 5% 5
5 BIOPHARM-THE TECHNOLOGY & BUSINESS OF BIOPHARMACEUTICALS 8558 1% 5% 5
6 BIOSEPARATION 5423 1% 3% 6
7 BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY 5267 2% 1% 18
8 BIOTECHNOLOGY AND BIOENGINEERING 5118 5% 0% 42
9 JOURNAL OF BIOTECHNOLOGY 4032 3% 0% 28
10 JOURNAL OF CHROMATOGRAPHY A 3650 6% 0% 54

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PLASMID PURIFICATION 581254 2% 81% 21 Search PLASMID+PURIFICATION Search PLASMID+PURIFICATION
2 PLASMID DNA 564068 14% 13% 128 Search PLASMID+DNA Search PLASMID+DNA
3 SUPERCOILED PLASMID DNA 461730 2% 84% 16 Search SUPERCOILED+PLASMID+DNA Search SUPERCOILED+PLASMID+DNA
4 ALKALINE LYSIS 231649 1% 52% 13 Search ALKALINE+LYSIS Search ALKALINE+LYSIS
5 PLASMID DNA PURIFICATION 213519 1% 69% 9 Search PLASMID+DNA+PURIFICATION Search PLASMID+DNA+PURIFICATION
6 PDNA VACCINES 171347 1% 100% 5 Search PDNA+VACCINES Search PDNA+VACCINES
7 PLASMID DNA PRODUCTION 171347 1% 100% 5 Search PLASMID+DNA+PRODUCTION Search PLASMID+DNA+PRODUCTION
8 PRE MIR 29 137078 0% 100% 4 Search PRE+MIR+29 Search PRE+MIR+29
9 SMALL DNA LIGANDS 137078 0% 100% 4 Search SMALL+DNA+LIGANDS Search SMALL+DNA+LIGANDS
10 SUPERCOILED 122388 1% 71% 5 Search SUPERCOILED Search SUPERCOILED

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 DIOGO, MM , QUEIROZ, JA , PRAZERES, DMF , (2005) CHROMATOGRAPHY OF PLASMID DNA.JOURNAL OF CHROMATOGRAPHY A. VOL. 1069. ISSUE 1. P. 3 -22 63 74% 111
2 SOUSA, F , PASSARINHA, L , QUEIROZ, JA , (2010) BIOMEDICAL APPLICATION OF PLASMID DNA IN GENE THERAPY: A NEW CHALLENGE FOR CHROMATOGRAPHY.BIOTECHNOLOGY AND GENETIC ENGINEERING REVIEWS, VOL 26. VOL. 26. ISSUE . P. 83-115 72 61% 2
3 XENOPOULOS, A , PATTNAIK, P , (2014) PRODUCTION AND PURIFICATION OF PLASMID DNA VACCINES: IS THERE SCOPE FOR FURTHER INNOVATION?.EXPERT REVIEW OF VACCINES. VOL. 13. ISSUE 12. P. 1537 -1551 46 82% 5
4 GHANEM, A , HEALEY, R , ADLY, FG , (2013) CURRENT TRENDS IN SEPARATION OF PLASMID DNA VACCINES: A REVIEW.ANALYTICA CHIMICA ACTA. VOL. 760. ISSUE . P. 1-15 51 66% 23
5 ZHANG, ML , HU, D , LIU, MR , KONG, X , (2010) APPLICATION OF ION EXCHANGE CHROMATOGRAPHY FOR PHARMACEUTICAL PLASMID ANALYSIS.PROGRESS IN CHEMISTRY. VOL. 22. ISSUE 2-3. P. 482-488 45 76% 2
6 FERREIRA, GNM , (2005) CHROMATOGRAPHIC APPROACHES IN THE PURIFICATION OF PLASMID DNA FOR THERAPY AND VACCINATION.CHEMICAL ENGINEERING & TECHNOLOGY. VOL. 28. ISSUE 11. P. 1285-1294 43 74% 25
7 PRAZERES, DMF , FERREIRA, GNM , (2004) DESIGN OF FLOWSHEETS FOR THE RECOVERY AND PURIFICATION OF PLASMIDS FOR GENE THERAPY AND DNA VACCINATION.CHEMICAL ENGINEERING AND PROCESSING. VOL. 43. ISSUE 5. P. 609-624 40 82% 24
8 ISLAS-LUGO, F , VEGA-ESTRADA, J , ALVIS, CA , ORTEGA-LOPEZ, J , MONTES-HORCASITAS, MD , (2016) DEVELOPING STRATEGIES TO INCREASE PLASMID DNA PRODUCTION IN ESCHERICHIA COLI DH5 ALPHA USING BATCH CULTURE.JOURNAL OF BIOTECHNOLOGY. VOL. 233. ISSUE . P. 66 -73 28 85% 0
9 EON-DUVAL, A , (2003) LARGE-SCALE MANUFACTURING OF PLASMID DNA FOR GENE THERAPY AND DNA VACCINATION - PART 1: THE SUITABILITY OF CURRENT TECHNIQUES TO PURIFY PLASMID WITHOUT ADDING RNASE.BIOPHARM INTERNATIONAL. VOL. 16. ISSUE 8. P. 48-+ 40 82% 4
10 SOUSA, F , PRAZERES, DMF , QUEIROZ, JA , (2008) AFFINITY CHROMATOGRAPHY APPROACHES TO OVERCOME THE CHALLENGES OF PURIFYING PLASMID DNA.TRENDS IN BIOTECHNOLOGY. VOL. 26. ISSUE 9. P. 518-525 42 60% 52

Classes with closest relation at Level 1


Rank Class id link
1 32620 CHEMICALLY MODIFIED LMW HEPARIN//ANTI FACTOR IIA ACTIVITY//CR CANCEROL
2 35525 ANCIENT GREEN COLOR YARN//BLUE COLORANT//CHINESE BROCADE
3 18301 NAKED PLASMID DNA//HYDRODYNAMICS BASED TRANSFECTION//HYDRODYNAMIC GENE DELIVERY
4 35472 ANALYTICAL PITFALLS//ARTEFACTUAL RESULTS OF LABORATORY TESTS//AUTOMATED BLOOD COUNTERS
5 21162 NOTI LINKING CLONES//NOTI LINKING AND JUMPING CLONES//NOTL LINKING CLONES
6 25445 ENDOTOXIN REMOVAL//HUMAN LIKE COLLAGEN//SHAANXI DE ABLE BIOMED MAT
7 21184 EXPANDED BED ADSORPTION//EXPANDED BED//FLUIDIZED BED ADSORPTION
8 24380 BACTERIOPHAGE LAMBDA DEVELOPMENT//LAMBDA PLASMIDS//COLIPHAGE LAMBDA
9 35141 CALLIGONUM COMOSUM//CALLIGONUM//CALLIGONUM SPECIES
10 25922 TUBE RADIAL DISTRIBUT PHENOMENON//TUBE RADIAL DISTRIBUTION PHENOMENON TRDP//SLALOM CHROMATOGRAPHY

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