Class information for:
Level 1: UREA SYNTHESIS//HEPATIC AMINO NITROGEN CONVERSION//N ACETYLGLUTAMATE DEGRADATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
19398 507 33.9 45%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
630 3       HEPATIC ENCEPHALOPATHY//ASYMMETRIC DIMETHYLARGININE//HYPERAMMONEMIA 13067
1445 2             HEPATIC ENCEPHALOPATHY//HYPERAMMONEMIA//MINIMAL HEPATIC ENCEPHALOPATHY 7828
19398 1                   UREA SYNTHESIS//HEPATIC AMINO NITROGEN CONVERSION//N ACETYLGLUTAMATE DEGRADATION 507

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UREA SYNTHESIS authKW 626324 5% 40% 26
2 HEPATIC AMINO NITROGEN CONVERSION authKW 361359 1% 100% 6
3 N ACETYLGLUTAMATE DEGRADATION authKW 240906 1% 100% 4
4 N ACETYLGLUTAMATE SYNTHESIS authKW 240906 1% 100% 4
5 PEDIAT CHILD DEV REHABIL MED METAB DIS address 120453 0% 100% 2
6 N ACETYLGLUTAMATE authKW 115814 1% 38% 5
7 2 N 15GLUTAMINE authKW 60226 0% 100% 1
8 5 N 15GLUTAMINE GLUTAMINE CYCLE authKW 60226 0% 100% 1
9 66 H 2 GLUCOSE authKW 60226 0% 100% 1
10 ABRAMSON CHILD DEV address 60226 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 1624 48% 0% 241
2 Gastroenterology & Hepatology 722 12% 0% 61
3 Biophysics 430 11% 0% 58
4 Nutrition & Dietetics 331 7% 0% 37
5 Medicine, Research & Experimental 247 9% 0% 47
6 Endocrinology & Metabolism 96 7% 0% 33
7 Physiology 88 6% 0% 28
8 Medicine, General & Internal 34 6% 0% 28
9 Education, Scientific Disciplines 20 1% 0% 6
10 Cell Biology 17 5% 0% 26

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEDIAT CHILD DEV REHABIL MED METAB DIS 120453 0% 100% 2
2 ABRAMSON CHILD DEV 60226 0% 100% 1
3 CHILD DEV MOL DIS PEDIAT 60226 0% 100% 1
4 MED CHILD DEV REHABIL MED 60226 0% 100% 1
5 MED HEPATOL A 60226 0% 100% 1
6 NUMICO 60226 0% 100% 1
7 NUTR FOOD SCI NISHI KU 60226 0% 100% 1
8 PEDIAT CHILD DEV MOL DIS 60226 0% 100% 1
9 PEDIAT CHILD DEV REHABIL MED 60226 0% 100% 1
10 PHYSIOL CHEM HOPPE SEYLER STR 1 60226 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEMICAL JOURNAL 3785 8% 0% 43
2 EUROPEAN JOURNAL OF BIOCHEMISTRY 2031 5% 0% 26
3 JOURNAL OF HEPATOLOGY 2013 3% 0% 16
4 CLINICAL NUTRITION 2009 2% 0% 10
5 BIOCHEMICAL EDUCATION 1874 1% 1% 4
6 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 1596 2% 0% 9
7 ISI ATLAS OF SCIENCE-BIOCHEMISTRY 1002 0% 2% 1
8 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 1000 3% 0% 17
9 BIOCHIMICA ET BIOPHYSICA ACTA 986 4% 0% 22
10 HEPATOLOGY 975 3% 0% 14

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 UREA SYNTHESIS 626324 5% 40% 26 Search UREA+SYNTHESIS Search UREA+SYNTHESIS
2 HEPATIC AMINO NITROGEN CONVERSION 361359 1% 100% 6 Search HEPATIC+AMINO+NITROGEN+CONVERSION Search HEPATIC+AMINO+NITROGEN+CONVERSION
3 N ACETYLGLUTAMATE DEGRADATION 240906 1% 100% 4 Search N+ACETYLGLUTAMATE+DEGRADATION Search N+ACETYLGLUTAMATE+DEGRADATION
4 N ACETYLGLUTAMATE SYNTHESIS 240906 1% 100% 4 Search N+ACETYLGLUTAMATE+SYNTHESIS Search N+ACETYLGLUTAMATE+SYNTHESIS
5 N ACETYLGLUTAMATE 115814 1% 38% 5 Search N+ACETYLGLUTAMATE Search N+ACETYLGLUTAMATE
6 2 N 15GLUTAMINE 60226 0% 100% 1 Search 2+N+15GLUTAMINE Search 2+N+15GLUTAMINE
7 5 N 15GLUTAMINE GLUTAMINE CYCLE 60226 0% 100% 1 Search 5+N+15GLUTAMINE+GLUTAMINE+CYCLE Search 5+N+15GLUTAMINE+GLUTAMINE+CYCLE
8 66 H 2 GLUCOSE 60226 0% 100% 1 Search 66+H+2+GLUCOSE Search 66+H+2+GLUCOSE
9 ACETYLGLUTAMATE SYNTHETASE 60226 0% 100% 1 Search ACETYLGLUTAMATE+SYNTHETASE Search ACETYLGLUTAMATE+SYNTHETASE
10 ACID BASE EQUILIBRIUM METABOLIC ACIDOSIS RESPIRATORY ACIDOSIS PH 60226 0% 100% 1 Search ACID+BASE+EQUILIBRIUM+METABOLIC+ACIDOSIS+RESPIRATORY+ACIDOSIS+PH Search ACID+BASE+EQUILIBRIUM+METABOLIC+ACIDOSIS+RESPIRATORY+ACIDOSIS+PH

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MEIJER, AJ , LAMERS, WH , CHAMULEAU, RAFM , (1990) NITROGEN-METABOLISM AND ORNITHINE CYCLE FUNCTION.PHYSIOLOGICAL REVIEWS. VOL. 70. ISSUE 3. P. 701-748 96 27% 354
2 NISSIM, I , YUDKOFF, M , BROSNAN, JT , (1996) REGULATION OF [N-15]UREA SYNTHESIS FROM [5-N-15]GLUTAMINE - ROLE OF PH, HORMONES, AND PYRUVATE.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 271. ISSUE 49. P. 31234-31242 29 76% 24
3 HAUSSINGER, D , (1990) NITROGEN-METABOLISM IN LIVER - STRUCTURAL AND FUNCTIONAL-ORGANIZATION AND PHYSIOLOGICAL RELEVANCE.BIOCHEMICAL JOURNAL. VOL. 267. ISSUE 2. P. 281-290 42 48% 217
4 HAUSSINGER, D , (1998) HEPATIC GLUTAMINE TRANSPORT AND METABOLISM.ADVANCES IN ENZYMOLOGY, VOL 72. VOL. 72. ISSUE . P. 43-+ 53 34% 48
5 THOMSEN, KL , GRONBK, H , DAHLERUP, JF , AAGAARD, NK , CHRISTENSEN, LA , AGNHOLT, J , FRYSTYK, J , VILSTRUP, H , (2014) PREDNISOLONE BUT NOT INFLIXIMAB AGGRAVATES THE UPREGULATED HEPATIC NITROGEN ELIMINATION IN PATIENTS WITH ACTIVE INFLAMMATORY BOWEL DISEASE.INFLAMMATORY BOWEL DISEASES. VOL. 20. ISSUE 1. P. 7-13 21 50% 1
6 GLAVIND, E , AAGAARD, NK , GRONBAEK, H , MOLLER, HJ , ORNTOFT, NW , VILSTRUP, H , THOMSEN, KL , (2016) ALCOHOLIC HEPATITIS MARKEDLY DECREASES THE CAPACITY FOR UREA SYNTHESIS.PLOS ONE. VOL. 11. ISSUE 7. P. - 18 51% 0
7 CALDOVIC, L , TUCHMAN, M , (2003) N-ACETYLGLUTAMATE AND ITS CHANGING ROLE THROUGH EVOLUTION.BIOCHEMICAL JOURNAL. VOL. 372. ISSUE . P. 279-290 32 36% 69
8 CALDOVIC, L , LOPEZ, GY , HASKINS, N , PANGLAO, M , SHI, DS , MORIZONO, H , TUCHMAN, M , (2006) BIOCHEMICAL PROPERTIES OF RECOMBINANT HUMAN AND MOUSE N-ACETYLGLUTAMATE SYNTHASE.MOLECULAR GENETICS AND METABOLISM. VOL. 87. ISSUE 3. P. 226-232 17 63% 18
9 THOMSEN, KL , (2013) REGULATION OF UREA SYNTHESIS DURING THE ACUTE PHASE RESPONSE IN RATS.DANISH MEDICAL JOURNAL. VOL. 60. ISSUE 4. P. - 26 36% 0
10 NIELSEN, SS , GROFTE, T , GRONBAEK, H , TYGSTRUP, N , VILSTRUP, H , (2007) OPPOSITE EFFECTS ON REGULATION OF UREA SYNTHESIS BY EARLY AND LATE URAEMIA IN RATS.CLINICAL NUTRITION. VOL. 26. ISSUE 2. P. 245-251 17 61% 3

Classes with closest relation at Level 1


Rank Class id link
1 11094 METABOLIC ZONATION//LIVER ZONATION//HEPATOCYTE HETEROGENEITY
2 12192 SYSTEM A//SYSTEM N//ASC SYSTEM
3 4786 ORNITHINE TRANSCARBAMYLASE DEFICIENCY//HYPERAMMONEMIA//UREA CYCLE DISORDERS
4 11808 ADRENERGIC RECEPTOR BINDING//OTTAWA CARLETON BIOL BIOL//ADENOSINE 3 5 MONOPHOSPHATE CAMP
5 20634 CELL VOLUME//INTRACELLULAR WATER SPACE//ANISOTONICITY
6 35213 L GLUTAMINASE//MICROCOCCUS LUTEUS K 3//GLUTAMINASE
7 22069 ARGININE REPRESSOR//ARGININE REPRESSOR PROTEIN//ARGR
8 20728 OLEOYL ESTRONE//ZUCKER FA FA RAT//ESPECIAL RECERCA NUTR CIENCIA ALIMENTS
9 3173 GLUTAMINE//GLUTAMINE DIPEPTIDES//ALANYL GLUTAMINE
10 17345 ORNITHINE UREA CYCLE//OPSANUS BETA//GULF TOADFISH

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