Class information for:
Level 1: NETWORK PHARMACOLOGY//DRUG REPOSITIONING//SYSTEMS PHARMACOLOGY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
6856 1436 50.5 82%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
90 3       MATHEMATICAL & COMPUTATIONAL BIOLOGY//BIOINFORMATICS//BMC BIOINFORMATICS 77178
868 2             BMC BIOINFORMATICS//MATHEMATICAL & COMPUTATIONAL BIOLOGY//BIOINFORMATICS 11572
6856 1                   NETWORK PHARMACOLOGY//DRUG REPOSITIONING//SYSTEMS PHARMACOLOGY 1436

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NETWORK PHARMACOLOGY authKW 541597 3% 58% 44
2 DRUG REPOSITIONING authKW 347173 4% 31% 53
3 SYSTEMS PHARMACOLOGY authKW 263051 2% 35% 35
4 POLYPHARMACOLOGY authKW 245083 3% 27% 42
5 DRUG TARGET INTERACTION authKW 228668 2% 49% 22
6 SYST COHORT address 114810 1% 60% 9
7 DRUG REPURPOSING authKW 101179 2% 18% 26
8 DRUG TARGET INTERACTION PREDICTION authKW 85050 0% 100% 4
9 COMPUTATIONAL PHARMACOLOGY authKW 85046 0% 67% 6
10 DRUG TARGET NETWORK authKW 85046 0% 67% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Mathematical & Computational Biology 21512 23% 0% 324
2 Biochemical Research Methods 5043 20% 0% 291
3 Chemistry, Medicinal 2967 14% 0% 201
4 Biotechnology & Applied Microbiology 2629 19% 0% 274
5 Computer Science, Interdisciplinary Applications 2034 11% 0% 153
6 Integrative & Complementary Medicine 1886 5% 0% 65
7 Pharmacology & Pharmacy 1590 21% 0% 305
8 Multidisciplinary Sciences 784 4% 0% 60
9 Computer Science, Information Systems 713 6% 0% 91
10 Biochemistry & Molecular Biology 685 22% 0% 312

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SYST COHORT 114810 1% 60% 9
2 CHEMOGENOM 71750 1% 38% 9
3 SYST COHORTHIGASHI KU 66442 0% 63% 5
4 INFOCLOUD GRP 63788 0% 100% 3
5 MULTISCALE MED SCI 63782 0% 50% 6
6 NCI MODELING CANC DEV 53151 0% 50% 5
7 BIOINFORMAT DRUG DESIGN GRP 45975 1% 14% 15
8 TRANSLAT BIOINFORMAT CANC SYST BIOL 44291 0% 42% 5
9 EBIOL GRP 42525 0% 100% 2
10 MOL LIB INFORMAT 42525 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CHEMINFORMATICS 34165 2% 7% 24
2 DRUG DISCOVERY TODAY 21599 3% 2% 50
3 MOLECULAR INFORMATICS 20917 2% 4% 22
4 JOURNAL OF CHEMICAL INFORMATION AND MODELING 19156 4% 2% 53
5 BIOINFORMATICS 15367 6% 1% 88
6 MOLECULAR BIOSYSTEMS 13167 3% 2% 41
7 NATURE REVIEWS DRUG DISCOVERY 11972 2% 2% 23
8 BMC SYSTEMS BIOLOGY 10351 2% 2% 28
9 BMC BIOINFORMATICS 9784 4% 1% 59
10 BRIEFINGS IN BIOINFORMATICS 7801 1% 2% 16

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NETWORK PHARMACOLOGY 541597 3% 58% 44 Search NETWORK+PHARMACOLOGY Search NETWORK+PHARMACOLOGY
2 DRUG REPOSITIONING 347173 4% 31% 53 Search DRUG+REPOSITIONING Search DRUG+REPOSITIONING
3 SYSTEMS PHARMACOLOGY 263051 2% 35% 35 Search SYSTEMS+PHARMACOLOGY Search SYSTEMS+PHARMACOLOGY
4 POLYPHARMACOLOGY 245083 3% 27% 42 Search POLYPHARMACOLOGY Search POLYPHARMACOLOGY
5 DRUG TARGET INTERACTION 228668 2% 49% 22 Search DRUG+TARGET+INTERACTION Search DRUG+TARGET+INTERACTION
6 DRUG REPURPOSING 101179 2% 18% 26 Search DRUG+REPURPOSING Search DRUG+REPURPOSING
7 DRUG TARGET INTERACTION PREDICTION 85050 0% 100% 4 Search DRUG+TARGET+INTERACTION+PREDICTION Search DRUG+TARGET+INTERACTION+PREDICTION
8 COMPUTATIONAL PHARMACOLOGY 85046 0% 67% 6 Search COMPUTATIONAL+PHARMACOLOGY Search COMPUTATIONAL+PHARMACOLOGY
9 DRUG TARGET NETWORK 85046 0% 67% 6 Search DRUG+TARGET+NETWORK Search DRUG+TARGET+NETWORK
10 CHEMOGENOMICS 83631 2% 18% 22 Search CHEMOGENOMICS Search CHEMOGENOMICS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 LAVECCHIA, A , CERCHIA, C , (2016) IN SILICO METHODS TO ADDRESS POLYPHARMACOLOGY: CURRENT STATUS, APPLICATIONS AND FUTURE PERSPECTIVES.DRUG DISCOVERY TODAY. VOL. 21. ISSUE 2. P. 288 -298 46 54% 6
2 TANG, J , AITTOKALLIO, T , (2014) NETWORK PHARMACOLOGY STRATEGIES TOWARD MULTI-TARGET ANTICANCER THERAPIES: FROM COMPUTATIONAL MODELS TO EXPERIMENTAL DESIGN PRINCIPLES.CURRENT PHARMACEUTICAL DESIGN. VOL. 20. ISSUE 1. P. 23 -36 68 43% 15
3 CERETO-MASSAGUE, A , OJEDA, MJ , VALLS, C , MULERO, M , PUJADAS, G , GARCIA-VALLVE, S , (2015) TOOLS FOR IN SILICO TARGET FISHING.METHODS. VOL. 71. ISSUE . P. 98 -103 41 65% 12
4 PEREZ-NUENO, VI , (2015) USING QUANTITATIVE SYSTEMS PHARMACOLOGY FOR NOVEL DRUG DISCOVERY.EXPERT OPINION ON DRUG DISCOVERY. VOL. 10. ISSUE 12. P. 1315 -1331 56 55% 1
5 IVANOV, SM , LAGUNIN, AA , POROIKOV, VV , (2016) IN SILICO ASSESSMENT OF ADVERSE DRUG REACTIONS AND ASSOCIATED MECHANISMS.DRUG DISCOVERY TODAY. VOL. 21. ISSUE 1. P. 58 -71 48 49% 4
6 LI, J , ZHENG, S , CHEN, B , BUTTE, AJ , SWAMIDASS, SJ , LU, ZY , (2016) A SURVEY OF CURRENT TRENDS IN COMPUTATIONAL DRUG REPOSITIONING.BRIEFINGS IN BIOINFORMATICS. VOL. 17. ISSUE 1. P. 2 -12 36 46% 14
7 LE, DH , LE, L , (2016) SYSTEMS PHARMACOLOGY: A UNIFIED FRAMEWORK FOR PREDICTION OF DRUG-TARGET INTERACTIONS.CURRENT PHARMACEUTICAL DESIGN. VOL. 22. ISSUE 23. P. 3569 -3575 50 56% 1
8 WU, ZK , WANG, Y , CHEN, LN , (2013) NETWORK-BASED DRUG REPOSITIONING.MOLECULAR BIOSYSTEMS. VOL. 9. ISSUE 6. P. 1268 -1281 47 57% 35
9 CHEN, X , YAN, CC , ZHANG, XT , ZHANG, X , DAI, F , YIN, J , ZHANG, YD , (2016) DRUG-TARGET INTERACTION PREDICTION: DATABASES, WEB SERVERS AND COMPUTATIONAL MODELS.BRIEFINGS IN BIOINFORMATICS. VOL. 17. ISSUE 4. P. 696 -712 45 56% 2
10 MOUSAVIAN, Z , MASOUDI-NEJAD, A , (2014) DRUG-TARGET INTERACTION PREDICTION VIA CHEMOGENOMIC SPACE: LEARNING-BASED METHODS.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 10. ISSUE 9. P. 1273 -1287 41 69% 6

Classes with closest relation at Level 1


Rank Class id link
1 1013 LIFE SCI INFORMAT//B IT//LIMES PROGRAM UNIT CHEM BIOL MED CHEM
2 10975 GENE PRIORITIZATION//DISEASE GENE PREDICTION//HUMAN DISEASE NETWORK
3 21112 PAULLONES//ADV BIOINFORMAT SYST MED//NCI 60
4 16867 CLINICAL TRIAL RISK//DRUG DISCOVERY TODAY//TUFTS STUDY DRUG DEV
5 1353 JOURNAL OF CHEMICAL INFORMATION AND MODELING//VIRTUAL SCREENING//JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
6 9196 PROTEIN FUNCTION PREDICTION//COMPLEX SCI SOFTWARE//PHYLOGENETIC MOTIFS
7 4183 TEXT MIN//TEXT MINING//BIOMEDICAL TEXT MINING
8 681 PROTEIN INTERACTION NETWORK//PROTEIN PROTEIN INTERACTION NETWORK//ESSENTIAL PROTEINS
9 17618 TONGUE DIAGNOSIS//INFORMAT ACCESS SYNTH TCM DIAG 4//SUBOPTIMAL HEALTH STATUS
10 28572 CALCULATION OF BIOLOGICAL ACTIVITY//GAMMA BROMODYPNONE//3 AMINOISOCARBOSTYRYL

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