Class information for:
Level 1: HIGH DOSE METHOTREXATE//7 HYDROXYMETHOTREXATE//METHOTREXATE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15824 690 25.9 55%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
316 3       RHEUMATOLOGY//RHEUMATOID ARTHRITIS//RHEUMATOL 39766
1684 2             METHOTREXATE//FOLATE RECEPTOR//REDUCED FOLATE CARRIER 6769
15824 1                   HIGH DOSE METHOTREXATE//7 HYDROXYMETHOTREXATE//METHOTREXATE 690

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HIGH DOSE METHOTREXATE authKW 664077 6% 34% 44
2 7 HYDROXYMETHOTREXATE authKW 592761 3% 56% 24
3 METHOTREXATE authKW 421710 33% 4% 225
4 GLUCARPIDASE authKW 402297 1% 91% 10
5 CARBOXYPEPTIDASE G2 authKW 262819 2% 42% 14
6 METHOTREXATE TOXICITY authKW 158033 1% 36% 10
7 2 4 DIAMINO N 10 METHYLPTEROIC ACID authKW 88506 0% 100% 2
8 DAMPA authKW 88506 0% 100% 2
9 ELIMINATION DELAY authKW 88506 0% 100% 2
10 LD METHOTREXATE authKW 88506 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 3639 38% 0% 263
2 Pharmacology & Pharmacy 2033 33% 0% 226
3 Medical Laboratory Technology 1244 7% 0% 50
4 Chemistry, Analytical 1059 18% 0% 123
5 Hematology 939 12% 0% 82
6 Pediatrics 603 11% 0% 76
7 Biochemical Research Methods 289 8% 0% 53
8 Toxicology 91 4% 0% 29
9 Electrochemistry 37 3% 0% 18
10 Medicine, Research & Experimental 11 3% 0% 19

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARM PHARMACOKINET THER EUT DRUG MONITOR 88506 0% 100% 2
2 ANALYT MOL TOXICOL 44253 0% 100% 1
3 BIOMED CHEM NEOLEK RUDOLFA WEIGLA 12 44253 0% 100% 1
4 CHEM SCI BIOCHEM DIAGNOST 44253 0% 100% 1
5 CHILEAN PEDIAT ONCOL GRP 44253 0% 100% 1
6 CHIM VERTE CATALYSE CGCC CCVC 44253 0% 100% 1
7 CLIN PHARMACOKINET PHARMACODYNAM SECT 44253 0% 100% 1
8 CLIN PHARMACOL ROOM PHARM 44253 0% 100% 1
9 CLIN PHARMCOTHER Y 44253 0% 100% 1
10 DEPHEMATOL HEMATOONCOL 44253 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER CHEMOTHERAPY AND PHARMACOLOGY 18224 8% 1% 55
2 PEDIATRIC HEMATOLOGY AND ONCOLOGY 10523 3% 1% 22
3 THERAPEUTIC DRUG MONITORING 6239 3% 1% 23
4 CANCER DRUG DELIVERY 6096 1% 3% 4
5 JOURNAL OF ONCOLOGY PHARMACY PRACTICE 5361 1% 2% 5
6 CANCER TREATMENT REPORTS 3374 2% 1% 13
7 PEDIATRIC BLOOD & CANCER 2485 2% 0% 16
8 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 1597 3% 0% 21
9 RECENT RESULTS IN CANCER RESEARCH 1343 1% 1% 4
10 JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS 985 1% 0% 9

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HIGH DOSE METHOTREXATE 664077 6% 34% 44 Search HIGH+DOSE+METHOTREXATE Search HIGH+DOSE+METHOTREXATE
2 7 HYDROXYMETHOTREXATE 592761 3% 56% 24 Search 7+HYDROXYMETHOTREXATE Search 7+HYDROXYMETHOTREXATE
3 METHOTREXATE 421710 33% 4% 225 Search METHOTREXATE Search METHOTREXATE
4 GLUCARPIDASE 402297 1% 91% 10 Search GLUCARPIDASE Search GLUCARPIDASE
5 CARBOXYPEPTIDASE G2 262819 2% 42% 14 Search CARBOXYPEPTIDASE+G2 Search CARBOXYPEPTIDASE+G2
6 METHOTREXATE TOXICITY 158033 1% 36% 10 Search METHOTREXATE+TOXICITY Search METHOTREXATE+TOXICITY
7 2 4 DIAMINO N 10 METHYLPTEROIC ACID 88506 0% 100% 2 Search 2+4+DIAMINO+N+10+METHYLPTEROIC+ACID Search 2+4+DIAMINO+N+10+METHYLPTEROIC+ACID
8 DAMPA 88506 0% 100% 2 Search DAMPA Search DAMPA
9 ELIMINATION DELAY 88506 0% 100% 2 Search ELIMINATION+DELAY Search ELIMINATION+DELAY
10 LD METHOTREXATE 88506 0% 100% 2 Search LD+METHOTREXATE Search LD+METHOTREXATE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 SCOTT, JR , ZHOU, YM , CHENG, C , WARD, DA , SWANSON, HD , MOLINELLI, AR , STEWART, CF , NAVID, F , JEHA, S , RELLING, MV , ET AL (2015) COMPARABLE EFFICACY WITH VARYING DOSAGES OF GLUCARPIDASE IN PEDIATRIC ONCOLOGY PATIENTS.PEDIATRIC BLOOD & CANCER. VOL. 62. ISSUE 9. P. 1518 -1522 23 100% 2
2 WIDEMANN, BC , ADAMSON, PC , (2006) UNDERSTANDING AND MANAGING METHOTREXATE NEPHROTOXICITY.ONCOLOGIST. VOL. 11. ISSUE 6. P. 694-703 30 71% 171
3 SELESOVSKA, R , JANIKOVA-BANDZUCHOVA, L , CHYLKOVA, J , (2015) SENSITIVE VOLTAMMETRIC SENSOR BASED ON BORON-DOPED DIAMOND ELECTRODE FOR DETERMINATION OF THE CHEMOTHERAPEUTIC DRUG METHOTREXATE IN PHARMACEUTICAL AND BIOLOGICAL SAMPLES.ELECTROANALYSIS. VOL. 27. ISSUE 1. P. 42 -51 28 65% 5
4 RUBINO, FM , (2001) SEPARATION METHODS FOR METHOTREXATE, ITS STRUCTURAL ANALOGUES AND METABOLITES.JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 764. ISSUE 1-2. P. 217 -254 58 46% 44
5 PATTERSON, DM , LEE, SM , (2010) GLUCARPIDASE FOLLOWING HIGH-DOSE METHOTREXATE: UPDATE ON DEVELOPMENT.EXPERT OPINION ON BIOLOGICAL THERAPY. VOL. 10. ISSUE 1. P. 105-111 27 79% 10
6 WIDEMANN, BC , BALIS, FM , KIM, A , BORON, M , JAYAPRAKASH, N , SHALABI, A , O'BRIEN, M , EBY, M , COLE, DE , MURPHY, RF , ET AL (2010) GLUCARPIDASE, LEUCOVORIN, AND THYMIDINE FOR HIGH-DOSE METHOTREXATE-INDUCED RENAL DYSFUNCTION: CLINICAL AND PHARMACOLOGIC FACTORS AFFECTING OUTCOME.JOURNAL OF CLINICAL ONCOLOGY. VOL. 28. ISSUE 25. P. 3979-3986 22 92% 27
7 BLASCO, H , SILLY, S , TOURNAMILLE, JF , GYAN, E , SENECAL, D , ANDRE, V , COLOMBAT, P , LE GUELLEC, C , (2008) THE NEED FOR A BETTER DEFINITION OF THERAPEUTIC INDICATIONS OF CARBOXYPEPTIDASE IN DELAYED ELIMINATION OF METHOTREXATE.THERAPIE. VOL. 63. ISSUE 1. P. 19 -28 26 87% 2
8 DOMBROWSKY, E , JAYARAMAN, B , NARAYAN, M , BARRETT, JS , (2011) EVALUATING PERFORMANCE OF A DECISION SUPPORT SYSTEM TO IMPROVE METHOTREXATE PHARMACOTHERAPY IN CHILDREN AND YOUNG ADULTS WITH CANCER.THERAPEUTIC DRUG MONITORING. VOL. 33. ISSUE 1. P. 99-107 20 95% 11
9 CHLADKOVA, J , HAK, J , MARTINKOVA, J , CHLADEK, J , (2010) HIGH-DOSE METHOTREXATE IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA: 7-HYDROXYMETHOTREXATE SYSTEMIC EXPOSURE AND URINARY CONCENTRATIONS AT THE STEADY STATE CORRELATE WELL WITH THOSE OF METHOTREXATE.ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH. VOL. 60. ISSUE 12. P. 769-775 25 81% 0
10 CHRISTENSEN, AM , PAULEY, JL , MOLINELLI, AR , PANETTA, JC , WARD, DA , STEWART, CF , HOFFMAN, JM , HOWARD, SC , PUI, CH , PAPPO, AS , ET AL (2012) RESUMPTION OF HIGH-DOSE METHOTREXATE AFTER ACUTE KIDNEY INJURY AND GLUCARPIDASE USE IN PEDIATRIC ONCOLOGY PATIENTS.CANCER. VOL. 118. ISSUE 17. P. 4321 -4330 21 84% 9

Classes with closest relation at Level 1


Rank Class id link
1 26370 METHOTREXATE//INTESTINAL DAMAGE//ABSORPTIVE FUNCTION OF THE INTESTINE
2 2341 REDUCED FOLATE CARRIER//FOLYLPOLYGLUTAMATE SYNTHETASE//ANTIFOLATE
3 3319 METHOTREXATE//RHEUMATOID ARTHRITIS//METHOTREXATE POLYGLUTAMATES
4 6990 ACUTE LYMPHOBLASTIC LEUKEMIA//TESTICULAR RELAPSE//TESTICULAR LEUKEMIA
5 10766 ETOPOSIDE//ETOPOSIDE PHOSPHATE//ORAL ETOPOSIDE
6 7336 LATE EFFECTS//INTRATHECAL METHOTREXATE//COGNITIVE LATE EFFECTS
7 17643 ASAN FDN//AGROPHARMA//DA 125
8 7353 URIDINE PHOSPHORYLASE//5 PHENYLTHIOACYCLOURIDINE//LEUCOVORIN
9 2658 OSTEOSARCOMA//MUSCULOSKELETAL ONCOL//METASTATIC OSTEOSARCOMA
10 26433 6 MALEIMIDOCAPROYLHYDRAZONE DERIVATIVE OF DOXORUBICIN//METHOTREXATE ALBUMIN//256 CARCINOSARCOMA WALKER

Go to start page