Class information for:
Level 1: METHOTREXATE//RHEUMATOID ARTHRITIS//METHOTREXATE POLYGLUTAMATES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3319 2010 36.2 73%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
316 3       RHEUMATOLOGY//RHEUMATOID ARTHRITIS//RHEUMATOL 39766
1684 2             METHOTREXATE//FOLATE RECEPTOR//REDUCED FOLATE CARRIER 6769
3319 1                   METHOTREXATE//RHEUMATOID ARTHRITIS//METHOTREXATE POLYGLUTAMATES 2010

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 METHOTREXATE authKW 1326212 34% 13% 681
2 RHEUMATOID ARTHRITIS authKW 261324 29% 3% 584
3 METHOTREXATE POLYGLUTAMATES authKW 168830 1% 65% 17
4 RHEUMATOLOGY WoSSC 163061 52% 1% 1036
5 JOURNAL OF RHEUMATOLOGY journal 76439 13% 2% 253
6 SUBCUTANEOUS METHOTREXATE authKW 63290 0% 83% 5
7 DMARDS authKW 52829 2% 10% 34
8 DISEASE MODIFYING ANTIRHEUMATIC DRUGS authKW 51154 2% 10% 33
9 MX 68 authKW 47465 0% 63% 5
10 CH 1504 authKW 45570 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Rheumatology 163061 52% 1% 1036
2 Dermatology 3302 10% 0% 204
3 Pharmacology & Pharmacy 888 15% 0% 292
4 Medicine, General & Internal 863 11% 0% 222
5 Immunology 55 4% 0% 90
6 Toxicology 33 2% 0% 41
7 Allergy 10 1% 0% 11
8 Geriatrics & Gerontology 9 1% 0% 13
9 Medicine, Research & Experimental 5 2% 0% 38
10 Respiratory System 5 1% 0% 21

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RHEUMATOL 29278 14% 1% 279
2 ADV TRAINING HLTH SCI TECHNOL 27118 0% 36% 5
3 MOL ONCOL GRP CI 22776 0% 25% 6
4 CLIN PHARMSHINAGAWA KU 20252 0% 67% 2
5 HIGHER HLTH SCI NORTH ISCS N 20252 0% 67% 2
6 ABORAT INT DRUG MONITORING 15190 0% 100% 1
7 ABT INNERE MED HAMATOL 5 15190 0% 100% 1
8 ALLERG SKIN DIS 15190 0% 100% 1
9 ALLGEMEINE KLIN POLIKLIN KINDERHEILKUNDE 15190 0% 100% 1
10 ANESTEZIYOL REANIMAYSON ANABILIM DALI 15190 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF RHEUMATOLOGY 76439 13% 2% 253
2 BRITISH JOURNAL OF RHEUMATOLOGY 34574 4% 3% 71
3 ARTHRITIS AND RHEUMATISM 26492 7% 1% 134
4 CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 26473 5% 2% 98
5 SEMINARS IN ARTHRITIS AND RHEUMATISM 12360 2% 2% 40
6 ZEITSCHRIFT FUR RHEUMATOLOGIE 11428 2% 2% 42
7 ANNALS OF THE RHEUMATIC DISEASES 9783 4% 1% 76
8 CLINICAL RHEUMATOLOGY 8238 3% 1% 54
9 RHEUMATIC DISEASE CLINICS OF NORTH AMERICA 5837 1% 2% 24
10 AKTUELLE RHEUMATOLOGIE 5612 1% 2% 21

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 METHOTREXATE 1326212 34% 13% 681 Search METHOTREXATE Search METHOTREXATE
2 RHEUMATOID ARTHRITIS 261324 29% 3% 584 Search RHEUMATOID+ARTHRITIS Search RHEUMATOID+ARTHRITIS
3 METHOTREXATE POLYGLUTAMATES 168830 1% 65% 17 Search METHOTREXATE+POLYGLUTAMATES Search METHOTREXATE+POLYGLUTAMATES
4 SUBCUTANEOUS METHOTREXATE 63290 0% 83% 5 Search SUBCUTANEOUS+METHOTREXATE Search SUBCUTANEOUS+METHOTREXATE
5 DMARDS 52829 2% 10% 34 Search DMARDS Search DMARDS
6 DISEASE MODIFYING ANTIRHEUMATIC DRUGS 51154 2% 10% 33 Search DISEASE+MODIFYING+ANTIRHEUMATIC+DRUGS Search DISEASE+MODIFYING+ANTIRHEUMATIC+DRUGS
7 MX 68 47465 0% 63% 5 Search MX+68 Search MX+68
8 CH 1504 45570 0% 100% 3 Search CH+1504 Search CH+1504
9 THERAPEUTIC SEGMENT 45570 0% 100% 3 Search THERAPEUTIC+SEGMENT Search THERAPEUTIC+SEGMENT
10 LONGTERM TREATMENT 34716 0% 57% 4 Search LONGTERM+TREATMENT Search LONGTERM+TREATMENT

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 RAU, R , HERBORN, G , (2004) BENEFIT AND RISK OF METHOTREXATE TREATMENT IN RHEUMATOID ARTHRITIS.CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. VOL. 22. ISSUE 5. P. S83-S94 124 75% 29
2 BANNWARTH, B , LABAT, L , MORIDE, Y , SCHAEVERBEKE, T , (1994) METHOTREXATE IN RHEUMATOID-ARTHRITIS - AN UPDATE.DRUGS. VOL. 47. ISSUE 1. P. 25-50 119 87% 122
3 ROMAO, VC , LIMA, A , BERNARDES, M , CANHAO, H , FONSECA, JE , (2014) THREE DECADES OF LOW-DOSE METHOTREXATE IN RHEUMATOID ARTHRITIS: CAN WE PREDICT TOXICITY?.IMMUNOLOGIC RESEARCH. VOL. 60. ISSUE 2-3. P. 289 -310 98 63% 4
4 RAU, R , (1994) METHOTREXATE TREATMENT OF RHEUMATOID-ARTHRITIS 1994 - AN OVERVIEW.ZEITSCHRIFT FUR RHEUMATOLOGIE. VOL. 53. ISSUE 4. P. 199-229 125 84% 12
5 VERDIER, MC , TRIBUT, O , BODEAU, S , RIHOUEY, D , BENTUE-FERRER, D , (2011) LEVEL OF EVIDENCE FOR THERAPEUTIC DRUG MONITORING OF LOW DOSE METHOTREXATE IN INFLAMMATORY DISEASES.THERAPIE. VOL. 66. ISSUE 1. P. 63 -72 71 88% 1
6 CRONSTEIN, BN , (2005) LOW-DOSE METHOTREXATE: A MAINSTAY IN THE TREATMENT OF RHEUMATOID ARTHRITIS.PHARMACOLOGICAL REVIEWS. VOL. 57. ISSUE 2. P. 163-172 81 64% 240
7 WEST, SG , (1997) METHOTREXATE HEPATOTOXICITY.RHEUMATIC DISEASE CLINICS OF NORTH AMERICA. VOL. 23. ISSUE 4. P. 883-& 99 84% 59
8 CHEN, YH , ZOU, K , SUN, JH , YANG, Y , LIU, G , (2017) ARE GENE POLYMORPHISMS RELATED TO TREATMENT OUTCOMES OF METHOTREXATE IN PATIENTS WITH RHEUMATOID ARTHRITIS? A SYSTEMATIC REVIEW AND META-ANALYSIS.PHARMACOGENOMICS. VOL. 18. ISSUE 2. P. 175 -195 66 80% 0
9 VISSER, K , VAN DER HEIJDE, DMFM , (2009) RISK AND MANAGEMENT OF LIVER TOXICITY DURING METHOTREXATE TREATMENT IN RHEUMATOID AND PSORIATIC ARTHRITIS: A SYSTEMATIC REVIEW OF THE LITERATURE.CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. VOL. 27. ISSUE 6. P. 1017-1025 59 87% 41
10 COLEBATCH, AN , MARKS, JL , EDWARDS, CJ , (2011) SAFETY OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS, INCLUDING ASPIRIN AND PARACETAMOL (ACETAMINOPHEN) IN PEOPLE RECEIVING METHOTREXATE FOR INFLAMMATORY ARTHRITIS (RHEUMATOID ARTHRITIS, ANKYLOSING SPONDYLITIS, PSORIATIC ARTHRITIS, OTHER SPONDYLOARTHRITIS).COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 11. P. - 84 60% 12

Classes with closest relation at Level 1


Rank Class id link
1 19906 TENIDAP//SULFASALAZINE//SULPHASALAZINE
2 15824 HIGH DOSE METHOTREXATE//7 HYDROXYMETHOTREXATE//METHOTREXATE
3 33973 MDR I//RHEUMATOLOTA KU//BIOLOGIC AGENT THERAPY
4 661 RHEUMATOID ARTHRITIS//RHEUMATOLOGY//EARLY RHEUMATOID ARTHRITIS
5 26370 METHOTREXATE//INTESTINAL DAMAGE//ABSORPTIVE FUNCTION OF THE INTESTINE
6 22983 STEROID DEPENDENT ASTHMA//STEROID RESISTANT ASTHMA//ACUTE AIRWAY REACTION
7 27988 RELATIVE DRUG POTENCIES//ATLANTIC LATERAL SKULL BASE CLIN//ATP CONSUMING PROCESSES
8 14378 IMMUNODEFICIENCY ASSOCIATED LYMPHOPROLIFERATIVE DISORDERS//LYMPHOPROLIFERATIVE DISORDERS//METHOTREXATE
9 1141 RHEUMATOID ARTHRITIS//ABATACEPT//TOCILIZUMAB
10 14312 EXTRA ARTICULAR MANIFESTATIONS//RHEUMATOID VASCULITIS//INTERSTITIAL LUNG DISEASE

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