Class information for:
Level 1: ETOPOSIDE//ETOPOSIDE PHOSPHATE//ORAL ETOPOSIDE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
10766 1037 32.8 68%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
489 3       CISPLATIN//STABILITY CONSTANTS//JOURNAL OF INORGANIC BIOCHEMISTRY 23107
1065 2             CISPLATIN//NEPHROTOXICITY//PLATINUMII COMPLEXES 9996
10766 1                   ETOPOSIDE//ETOPOSIDE PHOSPHATE//ORAL ETOPOSIDE 1037

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ETOPOSIDE authKW 631926 20% 10% 205
2 ETOPOSIDE PHOSPHATE authKW 327273 2% 65% 17
3 ORAL ETOPOSIDE authKW 168694 2% 30% 19
4 LIMITED SAMPLING MODEL authKW 128007 1% 43% 10
5 CARBOPLATIN authKW 127929 10% 4% 106
6 TENIPOSIDE authKW 112206 2% 21% 18
7 CALVERT FORMULA authKW 103048 1% 50% 7
8 CANCER CHEMOTHERAPY AND PHARMACOLOGY journal 91646 15% 2% 151
9 PEDIAT PHARMACOKINET THER EUT address 70419 2% 15% 16
10 HLTH SCI CLIN PHARM address 67298 0% 57% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 16494 64% 0% 668
2 Pharmacology & Pharmacy 4486 39% 0% 405
3 Hematology 131 4% 0% 44
4 Medical Laboratory Technology 106 2% 0% 20
5 Toxicology 71 3% 0% 34
6 Transplantation 42 2% 0% 18
7 Pediatrics 36 3% 0% 32
8 Chemistry, Analytical 34 4% 0% 42
9 Biochemical Research Methods 13 2% 0% 23
10 Chemistry, Medicinal 10 2% 0% 18

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEDIAT PHARMACOKINET THER EUT 70419 2% 15% 16
2 HLTH SCI CLIN PHARM 67298 0% 57% 4
3 ROSWELL PK MEM MED 66248 0% 75% 3
4 PHARMACEUT 332 N LAUDERDALE 52997 0% 60% 3
5 PEDIAT PHARMACOKINET THER EUT PEDIAT 52573 0% 36% 5
6 PHARMACEUT EVALUAT 1 36798 0% 25% 5
7 ABT MED INFORMAT BIOMATH 29444 0% 100% 1
8 BONE MARROW TRANSPLANTAT PROGRAM MED 29444 0% 100% 1
9 CLIN PHARMACOL GRP TRANSLAT SUPPORT CORE 29444 0% 100% 1
10 CLIN PHARMACOL TOXICOL BRANCHWOODMONT OFF 29444 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER CHEMOTHERAPY AND PHARMACOLOGY 91646 15% 2% 151
2 CANCER TREATMENT REPORTS 11986 3% 1% 30
3 JOURNAL OF CLINICAL ONCOLOGY 6486 6% 0% 60
4 SEMINARS IN ONCOLOGY 6119 3% 1% 33
5 CANCER TREATMENT REVIEWS 5444 2% 1% 19
6 ANTI-CANCER DRUGS 3579 2% 1% 20
7 EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY 3494 1% 1% 15
8 CLINICAL PHARMACOKINETICS 3176 2% 1% 16
9 BULLETIN DU CANCER 2240 2% 0% 18
10 INVESTIGATIONAL NEW DRUGS 2238 1% 1% 14

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ETOPOSIDE 631926 20% 10% 205 Search ETOPOSIDE Search ETOPOSIDE
2 ETOPOSIDE PHOSPHATE 327273 2% 65% 17 Search ETOPOSIDE+PHOSPHATE Search ETOPOSIDE+PHOSPHATE
3 ORAL ETOPOSIDE 168694 2% 30% 19 Search ORAL+ETOPOSIDE Search ORAL+ETOPOSIDE
4 LIMITED SAMPLING MODEL 128007 1% 43% 10 Search LIMITED+SAMPLING+MODEL Search LIMITED+SAMPLING+MODEL
5 CARBOPLATIN 127929 10% 4% 106 Search CARBOPLATIN Search CARBOPLATIN
6 TENIPOSIDE 112206 2% 21% 18 Search TENIPOSIDE Search TENIPOSIDE
7 CALVERT FORMULA 103048 1% 50% 7 Search CALVERT+FORMULA Search CALVERT+FORMULA
8 CALVERT 66248 0% 75% 3 Search CALVERT Search CALVERT
9 ETOPOSIDE DOSAGE 58889 0% 100% 2 Search ETOPOSIDE+DOSAGE Search ETOPOSIDE+DOSAGE
10 PIPERINE ANALOGUE 58889 0% 100% 2 Search PIPERINE+ANALOGUE Search PIPERINE+ANALOGUE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 TOFFOLI, G , CORONA, G , BASSO, B , BOIOCCHI, M , (2004) PHARMACOKINETIC OPTIMISATION OF TREATMENT WITH ORAL ETOPOSIDE.CLINICAL PHARMACOKINETICS. VOL. 43. ISSUE 7. P. 441-466 107 73% 38
2 SIMON, A , NAGEL, D , KITCHEN, BJ , BODE, U , (1997) CLINICAL RELEVANCE OF ETOPOSIDE (VP-16) PHARMACOKINETICS IN CHILDREN AND ADULTS.INTERNATIONAL JOURNAL OF PEDIATRIC HEMATOLOGY/ONCOLOGY. VOL. 4. ISSUE 4. P. 401-414 78 77% 1
3 REZONJA, R , KNEZ, L , CUFER, T , MRHAR, A , (2013) ORAL TREATMENT WITH ETOPOSIDE IN SMALL CELL LUNG CANCER - DILEMMAS AND SOLUTIONS.RADIOLOGY AND ONCOLOGY. VOL. 47. ISSUE 1. P. 1-13 53 55% 6
4 WURTHWEIN, G , BOOS, J , (2001) SIMULATION TOOL FOR SCHEDULE-DEPENDENT ETOPOSIDE EXPOSURE BASED ON PHARMACOKINETIC FINDINGS PUBLISHED IN THE LITERATURE.ANTI-CANCER DRUGS. VOL. 12. ISSUE 2. P. 151 -158 47 89% 1
5 HOLTHUIS, JJM , (1988) ETOPOSIDE AND TENIPOSIDE - BIOANALYSIS, METABOLISM AND CLINICAL PHARMACOKINETICS.PHARMACEUTISCH WEEKBLAD-SCIENTIFIC EDITION. VOL. 10. ISSUE 3. P. 101-116 62 93% 37
6 CLARK, PI , SLEVIN, ML , (1987) THE CLINICAL-PHARMACOLOGY OF ETOPOSIDE AND TENIPOSIDE.CLINICAL PHARMACOKINETICS. VOL. 12. ISSUE 4. P. 223-252 66 69% 177
7 CHEN, CL , RAWWAS, J , SORRELL, A , EDDY, L , UCKUN, FM , (2001) BIOAVAILABILITY AND PHARMACOKINETIC FEATURES OF ETOPOSIDE IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS.LEUKEMIA & LYMPHOMA. VOL. 42. ISSUE 3. P. 317 -327 41 79% 10
8 LEE, KH , WANG, HK , (1995) ANTITUMOR AGENTS .165. CURRENT STATUS OF BIOANALYSIS OF ETOPOSIDE AND RELATED COMPOUNDS.JOURNAL OF FOOD AND DRUG ANALYSIS. VOL. 3. ISSUE 4. P. 209-232 49 72% 3
9 LOWIS, SP , NEWELL, DR , (1996) ETOPOSIDE FOR THE TREATMENT OF PAEDIATRIC TUMOURS: WHAT IS THE BEST WAY TO GIVE IT?.EUROPEAN JOURNAL OF CANCER. VOL. 32A. ISSUE 13. P. 2291-2297 42 78% 9
10 WURTHWEIN, G , KRUMPELMANN, S , TILLMANN, B , REAL, E , SCHULZE-WESTHOFF, P , JURGENS, H , BOOS, J , (1999) POPULATION PHARMACOKINETIC APPROACH TO COMPARE ORAL AND I.V. ADMINISTRATION OF ETOPOSIDE.ANTI-CANCER DRUGS. VOL. 10. ISSUE 9. P. 807-814 32 89% 11

Classes with closest relation at Level 1


Rank Class id link
1 8392 PODOPHYLLOTOXIN//DEOXYPODOPHYLLOTOXIN//PODOPHYLLUM HEXANDRUM
2 20934 CHEMOTHERAPY DOSING//DOSE BANDING//GRANULOCYTE MACROPHAGE PROGENITOR CELLS CFU GM
3 22427 CISPLATIN AQUATED SPECIES//MONOHYDRATED CISPLATIN//PLASMA ULTRAFILTRATES
4 15824 HIGH DOSE METHOTREXATE//7 HYDROXYMETHOTREXATE//METHOTREXATE
5 1350 SMALL CELL LUNG CANCER//AMRUBICIN//PROPHYLACTIC CRANIAL IRRADIATION
6 3335 CISPLATIN//NEPHROTOXICITY//CISPLATIN NEPHROTOXICITY
7 8111 IDARUBICIN//IDARUBICINOL//MODIFIED ANTIBIOT
8 1615 OVARIAN CANCER//RECURRENT OVARIAN CANCER//PEGYLATED LIPOSOMAL DOXORUBICIN
9 34581 MENOGARIL//DNA UNWINDING ACTIVITY//N O O TRIANGULAR PHARMACOPHORE
10 6772 IFOSFAMIDE//MESNA//TROFOSFAMIDE

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