Class information for:
Level 2: CHEMOKINES//CXCR4//CHEMOKINE RECEPTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
546 14674 45.1 91%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
578 3       CHEMOKINES//CXCR4//MACROPHAGE MIGRATION INHIBITORY FACTOR 16225
546 2             CHEMOKINES//CXCR4//CHEMOKINE RECEPTOR 14674
1531 1                   CXCR4//CXCL12//CXCR7 2610
5955 1                   TUMOR ASSOCIATED MACROPHAGES//TUMOUR ASSOCIATED MACROPHAGES//MACROPHAGE POLARIZATION 1552
7041 1                   INTERLEUKIN 8//CXCR2 ANTAGONIST//CXCR2 1412
7432 1                   BB 10010//CCL2//LEUKOTACTIN 1 1368
10205 1                   CXCR3//CXCL10//CXCL9 1082
14765 1                   CXCR2//INTERLEUKIN 8//CXCL5 751
14960 1                   CHEMOKINES//CHEMOKINE RECEPTOR//EXPT CLIN NEUROL 739
15178 1                   MONOCYTE CHEMOATTRACTANT PROTEIN 1//MCP 1//MCP 1 POLYMORPHISM 727
15536 1                   TARC//THYMUS AND ACTIVATION REGULATED CHEMOKINE//CCR4 707
16001 1                   FRACTALKINE//CX3CR1//CX3CL1 678
16547 1                   CCL20//CCR6//CCL21 648
18490 1                   CHEMOKINE STRUCTURE//LYMPHOTACTIN//CYTOKINE RECEPTOR INTERACTIONS 549
19733 1                   CCR2 ANTAGONIST//CCR2//CCR1 491
21331 1                   CXCL4//CTAP III//CXCL4L1 423
21780 1                   DARC//DUFFY BLOOD GROUP//DUFFY ANTIGEN 406
28577 1                   CXCL16//CXCR6//SR PSOX 204
32453 1                   CXCL14//DBC2//BRAK 139
35324 1                   CHEMOKINE LIKE FACTOR 1//CMTM3//CKLF1 99
35950 1                   CCL18//CC CHEMOKINE LIGAND 18//NIR1 89

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 CHEMOKINES authKW 1324507 17% 26% 2503
2 CXCR4 authKW 628196 5% 40% 748
3 CHEMOKINE RECEPTOR authKW 531279 4% 39% 652
4 CXCL12 authKW 307642 2% 51% 288
5 FRACTALKINE authKW 268772 1% 66% 196
6 CXCR7 authKW 233661 1% 85% 132
7 CXCR3 authKW 198000 1% 55% 173
8 TUMOR ASSOCIATED MACROPHAGES authKW 196526 2% 43% 221
9 SDF 1 authKW 159210 1% 39% 197
10 CX3CR1 authKW 123589 1% 50% 118

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Immunology 43818 27% 1% 3977
2 Oncology 15078 18% 0% 2667
3 Cell Biology 9423 15% 0% 2146
4 Hematology 8210 8% 0% 1165
5 Medicine, Research & Experimental 4126 7% 0% 1080
6 Biochemistry & Molecular Biology 3902 18% 0% 2586
7 Pathology 1873 4% 0% 570
8 Rheumatology 1025 2% 0% 268
9 Peripheral Vascular Diseases 806 3% 0% 433
10 Chemistry, Medicinal 588 3% 0% 392

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 MOL PREVENT MED 39712 1% 22% 88
2 MOL BIOREGULAT 22182 0% 28% 38
3 THEODOR KOCHER 20230 0% 17% 59
4 HUMAN DIS GENOM 19758 0% 22% 44
5 IMMUNOL 16441 6% 1% 822
6 CHEMOKINE BIOL 11697 0% 43% 13
7 WALTHER ONCOL 10756 0% 9% 57
8 MED SURG MATERNAL PEDIAT ADULT SCI 10517 0% 56% 9
9 CHEMOKINE GRP 9256 0% 64% 7
10 PATHOL 9063 10% 0% 1520

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF IMMUNOLOGY 21558 5% 1% 762
2 JOURNAL OF LEUKOCYTE BIOLOGY 19487 2% 4% 258
3 CYTOKINE 18325 1% 5% 199
4 JOURNAL OF NEUROIMMUNOLOGY 7063 1% 2% 154
5 BLOOD 4508 2% 1% 287
6 EUROPEAN JOURNAL OF IMMUNOLOGY 4495 1% 1% 174
7 JOURNAL OF EXPERIMENTAL MEDICINE 4282 1% 1% 164
8 JOURNAL OF INTERFERON AND CYTOKINE RESEARCH 3556 0% 3% 63
9 AMERICAN JOURNAL OF PATHOLOGY 3116 1% 1% 143
10 EUROPEAN CYTOKINE NETWORK 2981 0% 4% 38

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class		 LCSH search Wikipedia search
1 CHEMOKINES 1324507 17% 26% 2503 Search CHEMOKINES Search CHEMOKINES
2 CXCR4 628196 5% 40% 748 Search CXCR4 Search CXCR4
3 CHEMOKINE RECEPTOR 531279 4% 39% 652 Search CHEMOKINE+RECEPTOR Search CHEMOKINE+RECEPTOR
4 CXCL12 307642 2% 51% 288 Search CXCL12 Search CXCL12
5 FRACTALKINE 268772 1% 66% 196 Search FRACTALKINE Search FRACTALKINE
6 CXCR7 233661 1% 85% 132 Search CXCR7 Search CXCR7
7 CXCR3 198000 1% 55% 173 Search CXCR3 Search CXCR3
8 TUMOR ASSOCIATED MACROPHAGES 196526 2% 43% 221 Search TUMOR+ASSOCIATED+MACROPHAGES Search TUMOR+ASSOCIATED+MACROPHAGES
9 SDF 1 159210 1% 39% 197 Search SDF+1 Search SDF+1
10 CX3CR1 123589 1% 50% 118 Search CX3CR1 Search CX3CR1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BACHELERIE, F , BEN-BARUCH, A , BURKHARDT, AM , COMBADIERE, C , FARBER, JM , GRAHAM, GJ , HORUK, R , SPARRE-ULRICH, AH , LOCATI, M , LUSTER, AD , ET AL (2014) INTERNATIONAL UNION OF PHARMACOLOGY. LXXXIX. UPDATE ON THE EXTENDED FAMILY OF CHEMOKINE RECEPTORS AND INTRODUCING A NEW NOMENCLATURE FOR ATYPICAL CHEMOKINE RECEPTORS.PHARMACOLOGICAL REVIEWS. VOL. 66. ISSUE 1. P. 1 -79 533 50% 94
2 BAGGIOLINI, M , DEWALD, B , MOSER, B , (1994) INTERLEUKIN-8 AND RELATED CHEMOTACTIC CYTOKINES - CXC AND CC CHEMOKINES.ADVANCES IN IMMUNOLOGY, VOL 55. VOL. 55. ISSUE . P. 97 -179 290 66% 2016
3 ROLLINS, BJ , (1997) CHEMOKINES.BLOOD. VOL. 90. ISSUE 3. P. 909-928 199 75% 2036
4 ZHOU, Y , YAO, XH , BIAN, XW , WANG, JM , ZHOU, JM , XIANG, Y , YOSHIMURA, T , CHEN, KQ , GONG, WH , HUANG, J , (2014) THE ROLE OF CHEMOATTRACTANT RECEPTORS IN SHAPING THE TUMOR MICROENVIRONMENT.BIOMED RESEARCH INTERNATIONAL. VOL. . ISSUE . P. - 295 61% 6
5 AZAD, BB , NIMMAGADDA, S , CHATTERJEE, S , (2014) THE INTRICATE ROLE OF CXCR4 IN CANCER.EMERGING APPLICATIONS OF MOLECULAR IMAGING TO ONCOLOGY. VOL. 124. ISSUE . P. 31 -82 195 74% 39
6 WHITE, GE , IQBAL, AJ , GREAVES, DR , (2013) CC CHEMOKINE RECEPTORS AND CHRONIC INFLAMMATION-THERAPEUTIC OPPORTUNITIES AND PHARMACOLOGICAL CHALLENGES.PHARMACOLOGICAL REVIEWS. VOL. 65. ISSUE 1. P. 47-89 240 59% 62
7 VANDERCAPPELLEN, J , VAN DAMME, J , STRUYF, S , (2008) THE ROLE OF CXC CHEMOKINES AND THEIR RECEPTORS IN CANCER.CANCER LETTERS. VOL. 267. ISSUE 2. P. 226-244 154 84% 266
8 BAGGIOLINI, M , DEWALD, B , MOSER, B , (1997) HUMAN CHEMOKINES: AN UPDATE.ANNUAL REVIEW OF IMMUNOLOGY. VOL. 15. ISSUE . P. 675-705 134 75% 1677
9 VELA, M , ARIS, M , LLORENTE, M , GARCIA-SANZ, J , KREMER, L , (2015) CHEMOKINE RECEPTOR-SPECIFIC ANTIBODIES IN CANCER IMMUNOTHERAPY: ACHIEVEMENTS AND CHALLENGES.FRONTIERS IN IMMUNOLOGY. VOL. 6. ISSUE . P. - 179 71% 14
10 NIBBS, RJB , GRAHAM, GJ , (2013) IMMUNE REGULATION BY ATYPICAL CHEMOKINE RECEPTORS.NATURE REVIEWS IMMUNOLOGY. VOL. 13. ISSUE 11. P. 815 -829 152 84% 51

Classes with closest relation at Level 2


Rank Class id link
1 2107 LYMPHANGIOGENESIS//VEGF C//PODOPLANIN
2 1367 DENDRITIC CELLS//DC SIGN//LANGERHANS CELLS
3 3435 MACROPHAGE MIGRATION INHIBITORY FACTOR//MIF//MACROPHAGE MIGRATION INHIBITORY FACTOR MIF
4 2683 NEUTROPHIL EXTRACELLULAR TRAPS//SEVERE CONGENITAL NEUTROPENIA//NETOSIS
5 1852 INTERLEUKIN 1//INTERLEUKIN 1 RECEPTOR ANTAGONIST//POLYMORPHISM
6 821 SELECTINS//ADHESION MOLECULES//E SELECTIN
7 140 IMMUNOTHERAPY//DENDRITIC CELLS//CANCER IMMUNOLOGY IMMUNOTHERAPY
8 1534 OXIDIZED LDL//ATHEROSCLEROSIS//LOX 1
9 1321 INTERLEUKIN 12//CD23//INTERLEUKIN 4
10 1133 INTERLEUKIN 18//IL 33//IL 18

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