Class information for:
Level 1: TUMOR ASSOCIATED MACROPHAGES//TUMOUR ASSOCIATED MACROPHAGES//MACROPHAGE POLARIZATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5955 1552 55.2 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
578 3       CHEMOKINES//CXCR4//MACROPHAGE MIGRATION INHIBITORY FACTOR 16225
546 2             CHEMOKINES//CXCR4//CHEMOKINE RECEPTOR 14674
5955 1                   TUMOR ASSOCIATED MACROPHAGES//TUMOUR ASSOCIATED MACROPHAGES//MACROPHAGE POLARIZATION 1552

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TUMOR ASSOCIATED MACROPHAGES authKW 1586415 13% 40% 204
2 TUMOUR ASSOCIATED MACROPHAGES authKW 310459 2% 48% 33
3 MACROPHAGE POLARIZATION authKW 197485 3% 20% 51
4 TUMOR ASSOCIATED MACROPHAGES TAMS authKW 174850 1% 44% 20
5 M2 MACROPHAGES authKW 168476 2% 24% 35
6 CD204 authKW 103486 1% 48% 11
7 MACROPHAGES authKW 90464 21% 1% 323
8 CD163 authKW 85438 2% 13% 34
9 M2 POLARIZED MACROPHAGES authKW 78693 0% 100% 4
10 STUDY REPROD BIOL WOMENS HLTH address 72623 1% 31% 12

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 7731 37% 0% 576
2 Immunology 6724 32% 0% 500
3 Cell Biology 1629 18% 0% 280
4 Pathology 542 6% 0% 92
5 Medicine, Research & Experimental 492 8% 0% 120
6 Hematology 399 6% 0% 88
7 Respiratory System 43 2% 0% 31
8 Biochemistry & Molecular Biology 29 9% 0% 135
9 Materials Science, Biomaterials 19 1% 0% 13
10 Multidisciplinary Sciences 14 1% 0% 12

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STUDY REPROD BIOL WOMENS HLTH 72623 1% 31% 12
2 MYELOID CELL IMMUNOL 63725 1% 20% 16
3 MACROPHAGES ENDOTHELIAL CELLS GRP 59019 0% 100% 3
4 REPROD BIOL WOMENS HLTH 54643 0% 56% 5
5 ANGIOGENESIS TUMOR TARGETING UNIT 50352 1% 32% 8
6 INNATE IMMUN TOLERANCE 44964 0% 57% 4
7 HUMAN INNATE IMMUN 39346 0% 100% 2
8 LUNG CANCCANC HOSPTIANJIN LUNG CANC 39346 0% 100% 2
9 TUMOR INFLAMMAT ANGIOGENESIS 39346 0% 100% 2
10 DEV MOL BIOL 28546 2% 4% 36

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ONCOIMMUNOLOGY 10853 1% 2% 23
2 IMMUNOBIOLOGY 5910 2% 1% 31
3 ONCOTARGET 3041 3% 0% 44
4 JOURNAL OF LEUKOCYTE BIOLOGY 3028 2% 0% 33
5 CANCER CELL 2499 1% 1% 14
6 NATURE REVIEWS IMMUNOLOGY 2216 1% 1% 11
7 FRONTIERS IN IMMUNOLOGY 2165 1% 1% 18
8 IMMUNITY 2040 1% 1% 19
9 CANCER SCIENCE 1585 1% 0% 17
10 NATURE IMMUNOLOGY 1484 1% 1% 13

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TUMOR ASSOCIATED MACROPHAGES 1586415 13% 40% 204 Search TUMOR+ASSOCIATED+MACROPHAGES Search TUMOR+ASSOCIATED+MACROPHAGES
2 TUMOUR ASSOCIATED MACROPHAGES 310459 2% 48% 33 Search TUMOUR+ASSOCIATED+MACROPHAGES Search TUMOUR+ASSOCIATED+MACROPHAGES
3 MACROPHAGE POLARIZATION 197485 3% 20% 51 Search MACROPHAGE+POLARIZATION Search MACROPHAGE+POLARIZATION
4 TUMOR ASSOCIATED MACROPHAGES TAMS 174850 1% 44% 20 Search TUMOR+ASSOCIATED+MACROPHAGES+TAMS Search TUMOR+ASSOCIATED+MACROPHAGES+TAMS
5 M2 MACROPHAGES 168476 2% 24% 35 Search M2+MACROPHAGES Search M2+MACROPHAGES
6 CD204 103486 1% 48% 11 Search CD204 Search CD204
7 MACROPHAGES 90464 21% 1% 323 Search MACROPHAGES Search MACROPHAGES
8 CD163 85438 2% 13% 34 Search CD163 Search CD163
9 M2 POLARIZED MACROPHAGES 78693 0% 100% 4 Search M2+POLARIZED+MACROPHAGES Search M2+POLARIZED+MACROPHAGES
10 M1 MACROPHAGES 63448 1% 32% 10 Search M1+MACROPHAGES Search M1+MACROPHAGES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 QIAN, BZ , POLLARD, JW , (2010) MACROPHAGE DIVERSITY ENHANCES TUMOR PROGRESSION AND METASTASIS.CELL. VOL. 141. ISSUE 1. P. 39 -51 55 44% 1125
2 RUFFELL, B , COUSSENS, LM , (2015) MACROPHAGES AND THERAPEUTIC RESISTANCE IN CANCER.CANCER CELL. VOL. 27. ISSUE 4. P. 462 -472 58 48% 86
3 DE PALMA, M , LEWIS, CE , (2013) MACROPHAGE REGULATION OF TUMOR RESPONSES TO ANTICANCER THERAPIES.CANCER CELL. VOL. 23. ISSUE 3. P. 277 -286 48 62% 220
4 NOY, R , POLLARD, JW , (2014) TUMOR-ASSOCIATED MACROPHAGES: FROM MECHANISMS TO THERAPY.IMMUNITY. VOL. 41. ISSUE 1. P. 49 -61 49 40% 304
5 LAOUI, D , VAN OVERMEIRE, E , DE BAETSELIER, P , VAN GINDERACHTER, JA , RAES, G , (2014) FUNCTIONAL RELATIONSHIP BETWEEN TUMOR-ASSOCIATED MACROPNAGES AND MACROPNAGE COLONY-STIMULATING FACTOR AS CONTRIBUTORS TO CANCER PROGRESSION.FRONTIERS IN IMMUNOLOGY. VOL. 5. ISSUE . P. - 70 57% 27
6 TAKEYA, M , KOMOHARA, Y , (2016) ROLE OF TUMOR-ASSOCIATED MACROPHAGES IN HUMAN MALIGNANCIES: FRIEND OR FOE?.PATHOLOGY INTERNATIONAL. VOL. 66. ISSUE 9. P. 491 -505 76 55% 1
7 KEIRSSE, J , LAOUI, D , MOVAHEDI, K , VAN OVERMEIRE, E , VAN GINDERACHTER, JA , LAHMAR, Q , (2016) TISSUE-RESIDENT VERSUS MONOCYTE-DERIVED MACROPHAGES IN THE TUMOR MICROENVIRONMENT.BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER. VOL. 1865. ISSUE 1. P. 23 -34 74 43% 6
8 MANTOVANI, A , ALLAVENA, P , (2015) THE INTERACTION OF ANTICANCER THERAPIES WITH TUMOR-ASSOCIATED MACROPHAGES.JOURNAL OF EXPERIMENTAL MEDICINE. VOL. 212. ISSUE 4. P. 435 -445 47 48% 66
9 BISWAS, SK , ALLAVENA, P , MANTOVANI, A , (2013) TUMOR-ASSOCIATED MACROPHAGES: FUNCTIONAL DIVERSITY, CLINICAL SIGNIFICANCE, AND OPEN QUESTIONS.SEMINARS IN IMMUNOPATHOLOGY. VOL. 35. ISSUE 5. P. 585-600 64 49% 76
10 MURRAY, PJ , ALLEN, JE , BISWAS, SK , FISHER, EA , GILROY, DW , GOERDT, S , GORDON, S , HAMILTON, JA , IVASHKIV, LB , LAWRENCE, T , ET AL (2014) MACROPHAGE ACTIVATION AND POLARIZATION: NOMENCLATURE AND EXPERIMENTAL GUIDELINES.IMMUNITY. VOL. 41. ISSUE 1. P. 14 -20 24 55% 494

Classes with closest relation at Level 1


Rank Class id link
1 35950 CCL18//CC CHEMOKINE LIGAND 18//NIR1
2 7415 MYELOID DERIVED SUPPRESSOR CELLS//MDSC//MYELOID DERIVED SUPPRESSOR CELLS MDSC
3 18471 MONOCYTE SUBSETS//CD14CD16 MONOCYTES//CD14CD16
4 6447 CSF 1//MACROPHAGE COLONY STIMULATING FACTOR//M CSF
5 20081 MUCOSAL INFLAMMAT PROGRAM//INFLAMMATION AND INNATE IMMUNITY//HEPATIC OXYGEN CONSUMPTION
6 7432 BB 10010//CCL2//LEUKOTACTIN 1
7 18604 MISSISSIPPI HEART//CARDIOVASC SCI SECT//WILF FAMILY CARDIOVASC
8 4080 REGULATORY T CELLS//FOXP3//TUMOR INFILTRATING LYMPHOCYTES
9 20921 BASAL CELL CARCINOMA CELLS//NIJMEGEN MOL LIFE SCI 278//SILTUXIMAB
10 7275 CANCER ASSOCIATED FIBROBLASTS//JEFFERSON STEM CELL BIOL REGENERAT MED//MANCHESTER BREAST

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